Unglycosylated Soluble SARS-CoV-2 Receptor Binding Domain (RBD) Produced in E. coli Combined with the Army Liposomal Formulation Containing QS21 (ALFQ) Elicits Neutralizing Antibodies against Mismatched Variants
Balasubramaniyam, Arasu, Ryan, Emma, Brown, Dallas, Hamza, Therwa, Harrison, William, Gan, Michael, Sankhala, Rajeshwer S, Chen, Wei-Hung, Martinez, Elizabeth J, Jensen, Jaime L, Dussupt, Vincent, Mendez-Rivera, Letzibeth, Mayer, Sandra, King, Jocelyn, Michael, Nelson L, Regules, Jason, Krebs, Shelly, Rao, Mangala, Matyas, Gary R, Joyce, M Gordon, Batchelor, Adrian H, Gromowski, Gregory D, Dutta, Sheetij
Published in Vaccines (Basel) (25.12.2022)
Published in Vaccines (Basel) (25.12.2022)
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Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity
Jensen, Jaime L, Sankhala, Rajeshwer S, Dussupt, Vincent, Bai, Hongjun, Hajduczki, Agnes, Lal, Kerri G, Chang, William C, Martinez, Elizabeth J, Peterson, Caroline E, Golub, Emily S, Rees, Phyllis A, Mendez-Rivera, Letzibeth, Zemil, Michelle, Kavusak, Erin, Mayer, Sandra V, Wieczorek, Lindsay, Kannan, Shruthi, Doranz, Benjamin J, Davidson, Edgar, Yang, Eun Sung, Zhang, Yi, Chen, Man, Choe, Misook, Wang, Lingshu, Gromowski, Gregory D, Koup, Richard A, Michael, Nelson L, Polonis, Victoria R, Rolland, Morgane, Modjarrad, Kayvon, Krebs, Shelly J, Joyce, M Gordon
Published in Journal of virology (27.07.2023)
Published in Journal of virology (27.07.2023)
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Journal Article
Ad26.COV2.S and SARS-CoV-2 spike protein ferritin nanoparticle vaccine protect against SARS-CoV-2 Omicron BA.5 challenge in macaques
Yu, Jingyou, Thomas, Paul V., Sciacca, Michaela, Wu, Cindy, Liu, Jinyan, He, Xuan, Miller, Jessica, Hachmann, Nicole P., Surve, Nehalee, McMahan, Katherine, Jacob-Dolan, Catherine, Powers, Olivia, Hall, Kevin, Barrett, Julia, Hope, David, Mazurek, Camille R., Murdza, Tetyana, Chang, William C., Golub, Emily, Rees, Phyllis A., Peterson, Caroline E., Hajduczki, Agnes, Chen, Wei-Hung, Martinez, Elizabeth J., Hussin, Elizabeth, Lange, Camille, Gong, Hua, Matyas, Gary R., Rao, Mangala, Suthar, Mehul, Boursiquot, Mona, Cook, Anthony, Pessaint, Laurent, Lewis, Mark G., Andersen, Hanne, Bolton, Diane L., Michael, Nelson L., Joyce, M. Gordon, Modjarrad, Kayvon, Barouch, Dan H.
Published in Cell reports. Medicine (18.04.2023)
Published in Cell reports. Medicine (18.04.2023)
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Protection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN
Yu, Jingyou, Thomas, Paul V, McMahan, Katherine, Jacob-Dolan, Catherine, Liu, Jinyan, He, Xuan, Hope, David, Martinez, Elizabeth J, Chen, Wei-Hung, Sciacca, Michaela, Hachmann, Nicole P, Lifton, Michelle, Miller, Jessica, Powers, Olivia C, Hall, Kevin, Wu, Cindy, Barrett, Julia, Swafford, Isabella, Currier, Jeffrey R, King, Jocelyn, Corbitt, Courtney, Chang, William C, Golub, Emily, Rees, Phyllis A, Peterson, Caroline E, Hajduczki, Agnes, Hussin, Elizabeth, Lange, Camille, Gong, Hua, Matyas, Gary R, Rao, Mangala, Paquin-Proulx, Dominic, Gromowski, Gregory D, Lewis, Mark G, Andersen, Hanne, Davis-Gardner, Meredith, Suthar, Mehul S, Michael, Nelson L, Bolton, Diane L, Joyce, M Gordon, Modjarrad, Kayvon, Barouch, Dan H
Published in Science advances (25.11.2022)
Published in Science advances (25.11.2022)
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SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity
Joyce, M. Gordon, Chen, Wei-Hung, Sankhala, Rajeshwer S., Hajduczki, Agnes, Thomas, Paul V., Choe, Misook, Martinez, Elizabeth J., Chang, William C., Peterson, Caroline E., Morrison, Elaine B., Smith, Clayton, Chen, Rita E., Ahmed, Aslaa, Wieczorek, Lindsay, Anderson, Alexander, Case, James Brett, Li, Yifan, Oertel, Therese, Rosado, Lorean, Ganesh, Akshaya, Whalen, Connor, Carmen, Joshua M., Mendez-Rivera, Letzibeth, Karch, Christopher P., Gohain, Neelakshi, Villar, Zuzana, McCurdy, David, Beck, Zoltan, Kim, Jiae, Shrivastava, Shikha, Jobe, Ousman, Dussupt, Vincent, Molnar, Sebastian, Tran, Ursula, Kannadka, Chandrika B., Soman, Sandrine, Kuklis, Caitlin, Zemil, Michelle, Khanh, Htet, Wu, Weimin, Cole, Matthew A., Duso, Debra K., Kummer, Larry W., Lang, Tricia J., Muncil, Shania E., Currier, Jeffrey R., Krebs, Shelly J., Polonis, Victoria R., Rajan, Saravanan, McTamney, Patrick M., Esser, Mark T., Reiley, William W., Rolland, Morgane, de Val, Natalia, Diamond, Michael S., Gromowski, Gregory D., Matyas, Gary R., Rao, Mangala, Michael, Nelson L., Modjarrad, Kayvon
Published in Cell reports (Cambridge) (21.12.2021)
Published in Cell reports (Cambridge) (21.12.2021)
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Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations
Dussupt, Vincent, Sankhala, Rajeshwer S, Mendez-Rivera, Letzibeth, Townsley, Samantha M, Schmidt, Fabian, Wieczorek, Lindsay, Lal, Kerri G, Donofrio, Gina C, Tran, Ursula, Jackson, Nathaniel D, Zaky, Weam I, Zemil, Michelle, Tritsch, Sarah R, Chen, Wei-Hung, Martinez, Elizabeth J, Ahmed, Aslaa, Choe, Misook, Chang, William C, Hajduczki, Agnes, Jian, Ningbo, Peterson, Caroline E, Rees, Phyllis A, Rutkowska, Magdalena, Slike, Bonnie M, Selverian, Christopher N, Swafford, Isabella, Teng, I-Ting, Thomas, Paul V, Zhou, Tongqing, Smith, Clayton J, Currier, Jeffrey R, Kwong, Peter D, Rolland, Morgane, Davidson, Edgar, Doranz, Benjamin J, Mores, Christopher N, Hatziioannou, Theodora, Reiley, William W, Bieniasz, Paul D, Paquin-Proulx, Dominic, Gromowski, Gregory D, Polonis, Victoria R, Michael, Nelson L, Modjarrad, Kayvon, Joyce, M Gordon, Krebs, Shelly J
Published in Nature immunology (01.12.2021)
Published in Nature immunology (01.12.2021)
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Journal Article
Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques
King, Hannah A D, Joyce, M Gordon, Lakhal-Naouar, Ines, Ahmed, Aslaa, Cincotta, Camila Macedo, Subra, Caroline, Peachman, Kristina K, Hack, Holly R, Chen, Rita E, Thomas, Paul V, Chen, Wei-Hung, Sankhala, Rajeshwer S, Hajduczki, Agnes, Martinez, Elizabeth J, Peterson, Caroline E, Chang, William C, Choe, Misook, Smith, Clayton, Headley, Jarrett A, Elyard, Hanne A, Cook, Anthony, Anderson, Alexander, Wuertz, Kathryn McGuckin, Dong, Ming, Swafford, Isabella, Case, James B, Currier, Jeffrey R, Lal, Kerri G, Amare, Mihret F, Dussupt, Vincent, Molnar, Sebastian, Daye, Sharon P, Zeng, Xiankun, Barkei, Erica K, Alfson, Kendra, Staples, Hilary M, Carrion, Ricardo, Krebs, Shelly J, Paquin-Proulx, Dominic, Karasavvas, Nicos, Polonis, Victoria R, Jagodzinski, Linda L, Vasan, Sandhya, Scott, Paul T, Huang, Yaoxing, Nair, Manoj S, Ho, David D, de Val, Natalia, Diamond, Michael S, Lewis, Mark G, Rao, Mangala, Matyas, Gary R, Gromowski, Gregory D, Peel, Sheila A, Michael, Nelson L, Modjarrad, Kayvon, Bolton, Diane L
Published in Proceedings of the National Academy of Sciences - PNAS (21.09.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (21.09.2021)
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Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity
Chen, Wei-Hung, Hajduczki, Agnes, Martinez, Elizabeth J, Bai, Hongjun, Matz, Hanover, Hill, Thomas M, Lewitus, Eric, Chang, William C, Dawit, Layla, Peterson, Caroline E, Rees, Phyllis A, Ajayi, Adelola B, Golub, Emily S, Swafford, Isabella, Dussupt, Vincent, David, Sapna, Mayer, Sandra V, Soman, Sandrine, Kuklis, Caitlin, Corbitt, Courtney, King, Jocelyn, Choe, Misook, Sankhala, Rajeshwer S, Thomas, Paul V, Zemil, Michelle, Wieczorek, Lindsay, Hart, Tricia, Duso, Debora, Kummer, Larry, Yan, Lianying, Sterling, Spencer L, Laing, Eric D, Broder, Christopher C, Williams, Jazmean K, Davidson, Edgar, Doranz, Benjamin J, Krebs, Shelly J, Polonis, Victoria R, Paquin-Proulx, Dominic, Rolland, Morgane, Reiley, William W, Gromowski, Gregory D, Modjarrad, Kayvon, Dooley, Helen, Joyce, M Gordon
Published in Nature communications (03.02.2023)
Published in Nature communications (03.02.2023)
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Antibody targeting of conserved sites of vulnerability on the SARS-CoV-2 spike receptor-binding domain
Sankhala, Rajeshwer S., Dussupt, Vincent, Chen, Wei-Hung, Bai, Hongjun, Martinez, Elizabeth J., Jensen, Jaime L., Rees, Phyllis A., Hajduczki, Agnes, Chang, William C., Choe, Misook, Yan, Lianying, Sterling, Spencer L., Swafford, Isabella, Kuklis, Caitlin, Soman, Sandrine, King, Jocelyn, Corbitt, Courtney, Zemil, Michelle, Peterson, Caroline E., Mendez-Rivera, Letzibeth, Townsley, Samantha M., Donofrio, Gina C., Lal, Kerri G., Tran, Ursula, Green, Ethan C., Smith, Clayton, de Val, Natalia, Laing, Eric D., Broder, Christopher C., Currier, Jeffrey R., Gromowski, Gregory D., Wieczorek, Lindsay, Rolland, Morgane, Paquin-Proulx, Dominic, van Dyk, Dewald, Britton, Zachary, Rajan, Saravanan, Loo, Yueh Ming, McTamney, Patrick M., Esser, Mark T., Polonis, Victoria R., Michael, Nelson L., Krebs, Shelly J., Modjarrad, Kayvon, Joyce, M. Gordon
Published in Structure (London) (01.02.2024)
Published in Structure (London) (01.02.2024)
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Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques
Sankhala, Rajeshwer S, Lal, Kerri G, Jensen, Jaime L, Dussupt, Vincent, Mendez-Rivera, Letzibeth, Bai, Hongjun, Wieczorek, Lindsay, Mayer, Sandra V, Zemil, Michelle, Wagner, Danielle A, Townsley, Samantha M, Hajduczki, Agnes, Chang, William C, Chen, Wei-Hung, Donofrio, Gina C, Jian, Ningbo, King, Hannah A D, Lorang, Cynthia G, Martinez, Elizabeth J, Rees, Phyllis A, Peterson, Caroline E, Schmidt, Fabian, Hart, Tricia J, Duso, Debra K, Kummer, Lawrence W, Casey, Sean P, Williams, Jazmean K, Kannan, Shruthi, Slike, Bonnie M, Smith, Lauren, Swafford, Isabella, Thomas, Paul V, Tran, Ursula, Currier, Jeffrey R, Bolton, Diane L, Davidson, Edgar, Doranz, Benjamin J, Hatziioannou, Theodora, Bieniasz, Paul D, Paquin-Proulx, Dominic, Reiley, William W, Rolland, Morgane, Sullivan, Nancy J, Vasan, Sandhya, Collins, Natalie D, Modjarrad, Kayvon, Gromowski, Gregory D, Polonis, Victoria R, Michael, Nelson L, Krebs, Shelly J, Joyce, M Gordon
Published in Nature communications (03.01.2024)
Published in Nature communications (03.01.2024)
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A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge
Wuertz, Kathryn McGuckin, Barkei, Erica K, Chen, Wei-Hung, Martinez, Elizabeth J, Lakhal-Naouar, Ines, Jagodzinski, Linda L, Paquin-Proulx, Dominic, Gromowski, Gregory D, Swafford, Isabella, Ganesh, Akshaya, Dong, Ming, Zeng, Xiankun, Thomas, Paul V, Sankhala, Rajeshwer S, Hajduczki, Agnes, Peterson, Caroline E, Kuklis, Caitlin, Soman, Sandrine, Wieczorek, Lindsay, Zemil, Michelle, Anderson, Alexander, Darden, Janice, Hernandez, Heather, Grove, Hannah, Dussupt, Vincent, Hack, Holly, de la Barrera, Rafael, Zarling, Stasya, Wood, James F, Froude, Jeffrey W, Gagne, Matthew, Henry, Amy R, Mokhtari, Elham Bayat, Mudvari, Prakriti, Krebs, Shelly J, Pekosz, Andrew S, Currier, Jeffrey R, Kar, Swagata, Porto, Maciel, Winn, Adrienne, Radzyminski, Kamil, Lewis, Mark G, Vasan, Sandhya, Suthar, Mehul, Polonis, Victoria R, Matyas, Gary R, Boritz, Eli A, Douek, Daniel C, Seder, Robert A, Daye, Sharon P, Rao, Mangala, Peel, Sheila A, Joyce, M Gordon, Bolton, Diane L, Michael, Nelson L, Modjarrad, Kayvon
Published in npj vaccines (28.10.2021)
Published in npj vaccines (28.10.2021)
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A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine Is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model
Johnston, Sara C, Ricks, Keersten M, Lakhal-Naouar, Ines, Jay, Alexandra, Subra, Caroline, Raymond, Jo Lynne, King, Hannah A D, Rossi, Franco, Clements, Tamara L, Fetterer, David, Tostenson, Samantha, Cincotta, Camila Macedo, Hack, Holly R, Kuklis, Caitlin, Soman, Sandrine, King, Jocelyn, Peachman, Kristina K, Kim, Dohoon, Chen, Wei-Hung, Sankhala, Rajeshwer S, Martinez, Elizabeth J, Hajduczki, Agnes, Chang, William C, Choe, Misook, Thomas, Paul V, Peterson, Caroline E, Anderson, Alexander, Swafford, Isabella, Currier, Jeffrey R, Paquin-Proulx, Dominic, Jagodzinski, Linda L, Matyas, Gary R, Rao, Mangala, Gromowski, Gregory D, Peel, Sheila A, White, Lauren, Smith, Jeffrey M, Hooper, Jay W, Michael, Nelson L, Modjarrad, Kayvon, Joyce, M Gordon, Nalca, Aysegul, Bolton, Diane L, Pitt, Margaret L M
Published in Vaccines (Basel) (04.05.2022)
Published in Vaccines (Basel) (04.05.2022)
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SARS-CoV-2 ferritin nanoparticle vaccines produce hyperimmune equine sera with broad sarbecovirus activity
Martinez, Elizabeth J., Chang, William C., Chen, Wei-Hung, Hajduczki, Agnes, Thomas, Paul V., Jensen, Jaime L., Choe, Misook, Sankhala, Rajeshwer S., Peterson, Caroline E., Rees, Phyllis A., Kimner, Jordan, Soman, Sandrine, Kuklis, Caitlin, Mendez-Rivera, Letzibeth, Dussupt, Vincent, King, Jocelyn, Corbett, Courtney, Mayer, Sandra V., Fernandes, Aldon, Murzello, Kripa, Cookenham, Tres, Hvizdos, Janine, Kummer, Larry, Hart, Tricia, Lanzer, Kathleen, Gambacurta, Julian, Reagan, Matthew, Duso, Debbie, Vasan, Sandhya, Collins, Natalie D., Michael, Nelson L., Krebs, Shelly J., Gromowski, Gregory D., Modjarrad, Kayvon, Kaundinya, John, Joyce, M. Gordon
Published in iScience (01.10.2024)
Published in iScience (01.10.2024)
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Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques
King, Hannah A D, Gordon Joyce, M, Naouar, Ines Elakhal, Ahmed, Aslaa, Cincotta, Camila Macedo, Subra, Caroline, Peachman, Kristina K, Hack, Holly H, Chen, Rita E, Thomas, Paul V, Chen, Wei-Hung, Sankhala, Rajeshwer S, Hajduczki, Agnes, Martinez, Elizabeth J, Peterson, Caroline E, Chang, William C, Choe, Misook, Smith, Clayton, Headley, Jarrett A, Elyard, Hanne A, Cook, Anthony, Anderson, Alexander, Wuertz, Kathryn McGuckin, Dong, Ming, Swafford, Isabella, Case, James B, Currier, Jeffrey R, Lal, Kerri G, Amare, Mihret F, Dussupt, Vincent, Molnar, Sebastian, Daye, Sharon P, Zeng, Xiankun, Barkei, Erica K, Alfson, Kendra, Staples, Hilary M, Carrion, Ricardo, Krebs, Shelly J, Paquin-Proulx, Dominic, Karasavvas, Nicos, Polonis, Victoria R, Jagodzinski, Linda L, Vasan, Sandhya, Scott, Paul T, Huang, Yaoxing, Nair, Manoj S, Ho, David D, de Val, Natalia, Diamond, Michael S, Lewis, Mark G, Rao, Mangala, Matyas, Gary R, Gromowski, Gregory D, Peel, Sheila A, Michael, Nelson L, Modjarrad, Kayvon, Bolton, Diane L
Published in bioRxiv : the preprint server for biology (10.04.2021)
Published in bioRxiv : the preprint server for biology (10.04.2021)
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Journal Article
A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model
Johnston, Sara C, Ricks, Keersten M, Lakhal-Naouar, Ines, Jay, Alexandra, Subra, Caroline, Raymond, Jo Lynne, King, Hannah A D, Rossi, Franco, Clements, Tamara L, Fetterer, David, Tostenson, Samantha, Camila Macedo Cincotta, Hack, Holly R, Kuklis, Caitlin, Soman, Sandrine, King, Jocelyn, Peachman, Kristina K, Kim, Dohoon, Wei-Hung, Chen, Sankhala, Rajeshwer S, Martinez, Elizabeth J, Hajduczki, Agnes, Chang, William C, Choe, Misook, Thomas, Paul V, Peterson, Caroline E, Anderson, Alexander, Swafford, Isabella, Currier, Jeffrey R, Paquin-Proulx, Dominic, Jagodzinski, Linda L, Matyas, Gary R, Rao, Mangala, Gromowski, Gregory D, Peel, Sheila A, White, Lauren, Smith, Jeffrey M, Hooper, Jay W, Michael, Nelson L L, Modjarrad, Kayvon, M Gordon Joyce, Nalca, Aysegul, Bolton, Diane L, Pitt, Margaret Lm
Published in bioRxiv (28.03.2022)
Published in bioRxiv (28.03.2022)
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