Biomarkers for the clinical management of breast cancer: International perspective
Patani, Neill, Martin, Lesley‐Ann, Dowsett, Mitch
Published in International journal of cancer (01.07.2013)
Published in International journal of cancer (01.07.2013)
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Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor-Positive Breast Cancer
Herrera-Abreu, Maria Teresa, Palafox, Marta, Asghar, Uzma, Rivas, Martín A, Cutts, Rosalind J, Garcia-Murillas, Isaac, Pearson, Alex, Guzman, Marta, Rodriguez, Olga, Grueso, Judit, Bellet, Meritxell, Cortés, Javier, Elliott, Richard, Pancholi, Sunil, Baselga, José, Dowsett, Mitch, Martin, Lesley-Ann, Turner, Nicholas C, Serra, Violeta
Published in Cancer research (Chicago, Ill.) (15.04.2016)
Published in Cancer research (Chicago, Ill.) (15.04.2016)
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Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer
Simigdala, Nikiana, Gao, Qiong, Pancholi, Sunil, Roberg-Larsen, Hanne, Zvelebil, Marketa, Ribas, Ricardo, Folkerd, Elizabeth, Thompson, Andrew, Bhamra, Amandeep, Dowsett, Mitch, Martin, Lesley-Ann
Published in Breast cancer research : BCR (01.06.2016)
Published in Breast cancer research : BCR (01.06.2016)
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Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance
Martin, Lesley-Ann, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Pancholi, Sunil, Tenev, Tencho, Gellert, Pascal, Buluwela, Laki, Harrod, Alison, Thornhill, Allan, Nikitorowicz-Buniak, Joanna, Bhamra, Amandeep, Turgeon, Marc-Olivier, Poulogiannis, George, Gao, Qiong, Martins, Vera, Hills, Margaret, Garcia-Murillas, Isaac, Fribbens, Charlotte, Patani, Neill, Li, Zheqi, Sikora, Matthew J., Turner, Nicholas, Zwart, Wilbert, Oesterreich, Steffi, Carroll, Jason, Ali, Simak, Dowsett, Mitch
Published in Nature communications (30.11.2017)
Published in Nature communications (30.11.2017)
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Capture Hi-C identifies putative target genes at 33 breast cancer risk loci
Baxter, Joseph S., Leavy, Olivia C., Dryden, Nicola H., Maguire, Sarah, Johnson, Nichola, Fedele, Vita, Simigdala, Nikiana, Martin, Lesley-Ann, Andrews, Simon, Wingett, Steven W., Assiotis, Ioannis, Fenwick, Kerry, Chauhan, Ritika, Rust, Alistair G., Orr, Nick, Dudbridge, Frank, Haider, Syed, Fletcher, Olivia
Published in Nature communications (12.03.2018)
Published in Nature communications (12.03.2018)
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miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors
Bacci, Marina, Giannoni, Elisa, Fearns, Antony, Ribas, Ricardo, Gao, Qiong, Taddei, Maria Letizia, Pintus, Gianfranco, Dowsett, Mitch, Isacke, Clare M, Martin, Lesley-Ann, Chiarugi, Paola, Morandi, Andrea
Published in Cancer research (Chicago, Ill.) (15.03.2016)
Published in Cancer research (Chicago, Ill.) (15.03.2016)
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De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy
Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne-Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-Buniak, Joanna, Valenti, Melanie, Howell, Louise, Fleck, Roland A., Martin, Lesley-Ann, Kirkin, Vladimir, Leach, Martin O., Chung, Yuen-Li
Published in Autophagy (02.06.2020)
Published in Autophagy (02.06.2020)
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Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer
Bacci, Marina, Lorito, Nicla, Ippolito, Luigi, Ramazzotti, Matteo, Luti, Simone, Romagnoli, Simone, Parri, Matteo, Bianchini, Francesca, Cappellesso, Federica, Virga, Federico, Gao, Qiong, Simões, Bruno M., Marangoni, Elisabetta, Martin, Lesley-Ann, Comito, Giuseppina, Ferracin, Manuela, Giannoni, Elisa, Mazzone, Massimiliano, Chiarugi, Paola, Morandi, Andrea
Published in Cell reports (Cambridge) (02.07.2019)
Published in Cell reports (Cambridge) (02.07.2019)
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E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer
Bajrami, Ilirjana, Marlow, Rebecca, van de Ven, Marieke, Brough, Rachel, Pemberton, Helen N, Frankum, Jessica, Song, Feifei, Rafiq, Rumana, Konde, Asha, Krastev, Dragomir B, Menon, Malini, Campbell, James, Gulati, Aditi, Kumar, Rahul, Pettitt, Stephen J, Gurden, Mark D, Cardenosa, Marta Llorca, Chong, Irene, Gazinska, Patrycja, Wallberg, Fredrik, Sawyer, Elinor J, Martin, Lesley-Ann, Dowsett, Mitch, Linardopoulos, Spiros, Natrajan, Rachael, Ryan, Colm J, Derksen, Patrick W B, Jonkers, Jos, Tutt, Andrew N J, Ashworth, Alan, Lord, Christopher J
Published in Cancer discovery (01.04.2018)
Published in Cancer discovery (01.04.2018)
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GDNF―RET Signaling in ER-Positive Breast Cancers Is a Key Determinant of Response and Resistance to Aromatase Inhibitors
MORANDI, Andrea, MARTIN, Lesley-Ann, QIONG GAO, PANCHOLI, Sunil, MACKAY, Alan, ROBERTSON, David, ZVELEBIL, Marketa, DOWSETT, Mitch, PLAZA-MENACHO, Ivan, ISACKE, Clare M
Published in Cancer research (Chicago, Ill.) (15.06.2013)
Published in Cancer research (Chicago, Ill.) (15.06.2013)
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The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
Cocce, Kimberly J., Jasper, Jeff S., Desautels, Taylor K., Everett, Logan, Wardell, Suzanne, Westerling, Thomas, Baldi, Robert, Wright, Tricia M., Tavares, Kendall, Yllanes, Alex, Bae, Yeeun, Blitzer, Jeremy T., Logsdon, Craig, Rakiec, Daniel P., Ruddy, David A., Jiang, Tiancong, Broadwater, Gloria, Hyslop, Terry, Hall, Allison, Laine, Muriel, Phung, Linda, Greene, Geoffrey L., Martin, Lesley-Ann, Pancholi, Sunil, Dowsett, Mitch, Detre, Simone, Marks, Jeffrey R., Crawford, Gregory E., Brown, Myles, Norris, John D., Chang, Ching-yi, McDonnell, Donald P.
Published in Cell reports (Cambridge) (22.10.2019)
Published in Cell reports (Cambridge) (22.10.2019)
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Impact of aromatase inhibitor treatment on global gene expression and its association with antiproliferative response in ER+ breast cancer in postmenopausal patients
Gao, Qiong, López-Knowles, Elena, Cheang, Maggie Chon U, Morden, James, Ribas, Ricardo, Sidhu, Kally, Evans, David, Martins, Vera, Dodson, Andrew, Skene, Anthony, Holcombe, Chris, Mallon, Elizabeth, Evans, Abigail, Bliss, Judith M, Robertson, John, Smith, Ian, Martin, Lesley-Ann, Dowsett, Mitch
Published in Breast cancer research : BCR (31.12.2019)
Published in Breast cancer research : BCR (31.12.2019)
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Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer
Pancholi, Sunil, Leal, Mariana Ferreira, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Chateau-Joubert, Sophie, Zabaglo, Lila, Hills, Margaret, Dodson, Andrew, Gao, Qiong, Johnston, Stephen R, Dowsett, Mitch, Cosulich, Sabina C, Maragoni, Elisabetta, Martin, Lesley-Ann
Published in Breast cancer research : BCR (04.12.2019)
Published in Breast cancer research : BCR (04.12.2019)
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Src Is a Potential Therapeutic Target in Endocrine-Resistant Breast Cancer Exhibiting Low Estrogen Receptor-Mediated Transactivation
Guest, Stephanie K, Ribas, Ricardo, Pancholi, Sunil, Nikitorowicz-Buniak, Joanna, Simigdala, Nikiana, Dowsett, Mitch, Johnston, Stephen R, Martin, Lesley-Ann
Published in PloS one (01.06.2016)
Published in PloS one (01.06.2016)
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Mechanisms of Disease: angiogenesis and the management of breast cancer
Banerjee, Susana, Martin, Lesley-Ann, Dowsett, Mitch, Ashworth, Alan
Published in Nature clinical practice. Oncology (01.09.2007)
Published in Nature clinical practice. Oncology (01.09.2007)
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Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones
Cavazzoni, Andrea, Bonelli, Mara A, Fumarola, Claudia, La Monica, Silvia, Airoud, Kinda, Bertoni, Ramona, Alfieri, Roberta R, Galetti, Maricla, Tramonti, Stefano, Galvani, Elena, Harris, Adrian L, Martin, Lesley-Ann, Andreis, Daniele, Bottini, Alberto, Generali, Daniele, Petronini, Pier Giorgio
Published in Cancer letters (01.10.2012)
Published in Cancer letters (01.10.2012)
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mTOR inhibitors in advanced breast cancer: Ready for prime time?
Martin, Lesley-Ann, André, Fabrice, Campone, Mario, Bachelot, Thomas, Jerusalem, Guy
Published in Cancer treatment reviews (01.11.2013)
Published in Cancer treatment reviews (01.11.2013)
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Web Resource
Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer
Ribas, Ricardo, Pancholi, Sunil, Rani, Aradhana, Schuster, Eugene, Guest, Stephanie K, Nikitorowicz-Buniak, Joanna, Simigdala, Nikiana, Thornhill, Allan, Avogadri-Connors, Francesca, Cutler, Jr, Richard E, Lalani, Alshad S, Dowsett, Mitch, Johnston, Stephen R, Martin, Lesley-Ann
Published in Breast cancer research : BCR (08.06.2018)
Published in Breast cancer research : BCR (08.06.2018)
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Elacestrant demonstrates strong anti-estrogenic activity in PDX models of estrogen-receptor positive endocrine-resistant and fulvestrant-resistant breast cancer
Pancholi, Sunil, Simigdala, Nikiana, Ribas, Ricardo, Schuster, Eugene, Leal, Mariana Ferreira, Nikitorowicz-Buniak, Joanna, Rega, Camilla, Bihani, Teeru, Patel, Hitisha, Johnston, Stephen R., Dowsett, Mitch, Martin, Lesley-Ann
Published in NPJ breast cancer (29.11.2022)
Published in NPJ breast cancer (29.11.2022)
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ESR1 is co-expressed with closely adjacent uncharacterised genes spanning a breast cancer susceptibility locus at 6q25.1
Dunbier, Anita K, Anderson, Helen, Ghazoui, Zara, Lopez-Knowles, Elena, Pancholi, Sunil, Ribas, Ricardo, Drury, Suzanne, Sidhu, Kally, Leary, Alexandra, Martin, Lesley-Ann, Dowsett, Mitch
Published in PLoS genetics (01.04.2011)
Published in PLoS genetics (01.04.2011)
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