Tracking the Behavior of Monoclonal Antibody Product Quality Attributes Using a Multi-Attribute Method Workflow
Jakes, Craig, Millán-Martín, Silvia, Carillo, Sara, Scheffler, Kai, Zaborowska, Izabela, Bones, Jonathan
Published in Journal of the American Society for Mass Spectrometry (04.08.2021)
Published in Journal of the American Society for Mass Spectrometry (04.08.2021)
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Journal Article
Development of a Rapid Adeno-Associated Virus (AAV) Identity Testing Platform through Comprehensive Intact Mass Analysis of Full-Length AAV Capsid Proteins
Smith, Josh, Guapo, Felipe, Strasser, Lisa, Millán-Martín, Silvia, Milian, Steven G., Snyder, Richard O., Bones, Jonathan
Published in Journal of proteome research (20.12.2023)
Published in Journal of proteome research (20.12.2023)
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Journal Article
Comparative analysis of monoclonal antibody N-glycosylation using stable isotope labelling and UPLC-fluorescence-MS
Millán Martín, Silvia, Delporte, Cédric, Farrell, Amy, Navas Iglesias, Natalia, McLoughlin, Niaobh, Bones, Jonathan
Published in Analyst (London) (07.03.2015)
Published in Analyst (London) (07.03.2015)
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Journal Article
Expression, Purification, and Biochemical Characterization of Human Afamin
Altamirano, Alessandra, Naschberger, Andreas, Fürnrohr, Barbara G, Saldova, Radka, Struwe, Weston B, Jennings, Patrick M, Millán Martín, Silvia, Malic, Suzana, Plangger, Immanuel, Lechner, Stefan, Pisano, Reina, Peretti, Nicole, Linke, Bernd, Aguiar, Mario M, Fresser, Friedrich, Ritsch, Andreas, Lenac Rovis, Tihana, Goode, Christina, Rudd, Pauline M, Scheffzek, Klaus, Rupp, Bernhard, Dieplinger, Hans
Published in Journal of proteome research (02.03.2018)
Published in Journal of proteome research (02.03.2018)
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Journal Article
Fast and efficient digestion of adeno associated virus (AAV) capsid proteins for liquid chromatography mass spectrometry (LC-MS) based peptide mapping and post translational modification analysis (PTMs)
Guapo, Felipe, Strasser, Lisa, Millán-Martín, Silvia, Anderson, Ian, Bones, Jonathan
Published in Journal of pharmaceutical and biomedical analysis (05.01.2022)
Published in Journal of pharmaceutical and biomedical analysis (05.01.2022)
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Journal Article
Implementation of a LC-MS based multi-attribute method (MAM) and intact multi-attribute method (iMAM) workflow for the characterisation of a GLP-Fc fusion protein
Buckley, Ciarán, Millán-Martín, Silvia, Carillo, Sara, Füssl, Florian, MacHale, Ciara, Bones, Jonathan
Published in Analytical biochemistry (01.10.2024)
Published in Analytical biochemistry (01.10.2024)
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Journal Article
Inter-laboratory study of an optimised peptide mapping workflow using automated trypsin digestion for monitoring monoclonal antibody product quality attributes
Millán-Martín, Silvia, Jakes, Craig, Carillo, Sara, Buchanan, Tom, Guender, Marc, Kristensen, Dan Bach, Sloth, Trine Meiborg, Ørgaard, Martin, Cook, Ken, Bones, Jonathan
Published in Analytical and bioanalytical chemistry (01.10.2020)
Published in Analytical and bioanalytical chemistry (01.10.2020)
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Journal Article
Correlative N-glycan and charge variant analysis of cetuximab expressed in murine, chinese hamster and human expression systems
Trappe, Anne, Füssl, Florian, Millán-Martín, Silvia, Ronan, Rachel, Zaborowska, Izabella, Bones, Jonathan
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.04.2022)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.04.2022)
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Journal Article
Multi-Attribute Method (MAM): An Emerging Analytical Workflow for Biopharmaceutical Characterization, Batch Release and cGMP Purity Testing at the Peptide and Intact Protein Level
Millán-Martín, Silvia, Jakes, Craig, Carillo, Sara, Gallagher, Lizzie, Scheffler, Kai, Broster, Kelly, Bones, Jonathan
Published in Critical reviews in analytical chemistry (25.07.2023)
Published in Critical reviews in analytical chemistry (25.07.2023)
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Journal Article
2-Dimensional ultra-high performance liquid chromatography and DMT-MM derivatization paired with tandem mass spectrometry for comprehensive serum N-glycome characterization
Smith, Josh, Millán-Martín, Silvia, Mittermayr, Stefan, Hilborne, Vivian, Davey, Gavin, Polom, Karol, Roviello, Franco, Bones, Jonathan
Published in Analytica chimica acta (22.09.2021)
Published in Analytica chimica acta (22.09.2021)
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Journal Article
Exploring proteoforms of the IgG2 monoclonal antibody panitumumab using microchip capillary electrophoresis-mass spectrometry
Füssl, Florian, Carillo, Sara, Millán-Martín, Silvia, Jakes, Craig, Bora, Karina, Liberatori, Sabrina, Graham, James, Bones, Jonathan
Published in Journal of pharmaceutical and biomedical analysis (20.09.2023)
Published in Journal of pharmaceutical and biomedical analysis (20.09.2023)
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Journal Article
Optimisation of the use of sliding window deconvolution for comprehensive characterisation of trastuzumab and adalimumab charge variants by native high resolution mass spectrometry
Millán-Martín, Silvia, Carillo, Sara, Füssl, Florian, Sutton, Jennifer, Gazis, Paul, Cook, Ken, Scheffler, Kai, Bones, Jonathan
Published in European journal of pharmaceutics and biopharmaceutics (01.01.2021)
Published in European journal of pharmaceutics and biopharmaceutics (01.01.2021)
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Journal Article
Inline electrochemical reduction of NISTmAb for middle-up subunit liquid chromatography-mass spectrometry analysis
Morgan, Tomos E, Jakes, Craig, Brouwer, Hendrik-Jan, Millán-Martín, Silvia, Chervet, Jean-Pierre, Cook, Ken, Carillo, Sara, Bones, Jonathan
Published in Analyst (London) (25.10.2021)
Published in Analyst (London) (25.10.2021)
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Journal Article
Twoplex 12/13C6 aniline stable isotope and linkage‐specific sialic acid labeling 2D‐LC‐MS workflow for quantitative N‐glycomics
Albrecht, Simone, Mittermayr, Stefan, Smith, Josh, Martín, Silvia Millán, Doherty, Margaret, Bones, Jonathan
Published in Proteomics (Weinheim) (01.01.2017)
Published in Proteomics (Weinheim) (01.01.2017)
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Journal Article
Quantitative twoplex glycan analysis using 12C6 and 13C6 stable isotope 2-aminobenzoic acid labelling and capillary electrophoresis mass spectrometry
Váradi, Csaba, Mittermayr, Stefan, Millán-Martín, Silvia, Bones, Jonathan
Published in Analytical and bioanalytical chemistry (01.12.2016)
Published in Analytical and bioanalytical chemistry (01.12.2016)
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Journal Article