Pan-cancer landscape of homologous recombination deficiency
Nguyen, Luan, W. M. Martens, John, Van Hoeck, Arne, Cuppen, Edwin
Published in Nature communications (04.11.2020)
Published in Nature communications (04.11.2020)
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Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer
Hammerl, Dora, Martens, John W. M., Timmermans, Mieke, Smid, Marcel, Trapman-Jansen, Anita M., Foekens, Renée, Isaeva, Olga I., Voorwerk, Leonie, Balcioglu, Hayri E., Wijers, Rebecca, Nederlof, Iris, Salgado, Roberto, Horlings, Hugo, Kok, Marleen, Debets, Reno
Published in Nature communications (27.09.2021)
Published in Nature communications (27.09.2021)
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Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression
Ren, Jiang, Smid, Marcel, Iaria, Josephine, Salvatori, Daniela C F, van Dam, Hans, Zhu, Hong Jian, Martens, John W M, Ten Dijke, Peter
Published in Breast cancer research : BCR (18.09.2019)
Published in Breast cancer research : BCR (18.09.2019)
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A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy
McLaughlin, Ronan P, He, Jichao, van der Noord, Vera E, Redel, Jevin, Foekens, John A, Martens, John W M, Smid, Marcel, Zhang, Yinghui, van de Water, Bob
Published in Breast cancer research : BCR (01.07.2019)
Published in Breast cancer research : BCR (01.07.2019)
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Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression
He, Jichao, McLaughlin, Ronan P., van der Beek, Lambert, Canisius, Sander, Wessels, Lodewyk, Smid, Marcel, Martens, John W. M., Foekens, John A., Zhang, Yinghui, van de Water, Bob
Published in Oncogene (14.05.2020)
Published in Oncogene (14.05.2020)
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Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features
Mendelaar, Pauline A. J., Smid, Marcel, van Riet, Job, Angus, Lindsay, Labots, Mariette, Steeghs, Neeltje, Hendriks, Mathijs P., Cirkel, Geert A., van Rooijen, Johan M., Ten Tije, Albert J., Lolkema, Martijn P., Cuppen, Edwin, Sleijfer, Stefan, Martens, John W. M., Wilting, Saskia M.
Published in Nature communications (25.01.2021)
Published in Nature communications (25.01.2021)
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Anti-Epithelial Cell Adhesion Molecule Antibodies and the Detection of Circulating Normal-Like Breast Tumor Cells
Sieuwerts, Anieta M., Kraan, Jaco, Bolt, Joan, van der Spoel, Petra, Elstrodt, Fons, Schutte, Mieke, Martens, John W. M., Gratama, Jan-Willem, Sleijfer, Stefan, Foekens, John A.
Published in JNCI : Journal of the National Cancer Institute (07.01.2009)
Published in JNCI : Journal of the National Cancer Institute (07.01.2009)
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Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer
He, Jichao, McLaughlin, Ronan P., van der Noord, Vera, Foekens, John A., Martens, John W. M., van Westen, Gerard, Zhang, Yinghui, van de Water, Bob
Published in Breast cancer research and treatment (01.11.2019)
Published in Breast cancer research and treatment (01.11.2019)
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Molecular characterization of circulating tumor cells in large quantities of contaminating leukocytes by a multiplex real-time PCR
Sieuwerts, Anieta M, Kraan, Jaco, Bolt-de Vries, Joan, van der Spoel, Petra, Mostert, Bianca, Martens, John W. M, Gratama, Jan-Willem, Sleijfer, Stefan, Foekens, John A
Published in Breast cancer research and treatment (01.12.2009)
Published in Breast cancer research and treatment (01.12.2009)
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MicroRNAs as possible indicators of drug sensitivity in breast cancer cell lines
Uhr, Katharina, Prager-van der Smissen, Wendy J C, Heine, Anouk A J, Ozturk, Bahar, van Jaarsveld, Marijn T M, Boersma, Antonius W M, Jager, Agnes, Wiemer, Erik A C, Smid, Marcel, Foekens, John A, Martens, John W M
Published in PloS one (07.05.2019)
Published in PloS one (07.05.2019)
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HER2-low breast cancer shows a lower immune response compared to HER2-negative cases
van den Ende, Nadine S., Smid, Marcel, Timmermans, Annemieke, van Brakel, Johannes B., Hansum, Tim, Foekens, Renée, Trapman, Anita M. A. C., Heemskerk-Gerritsen, Bernadette A. M., Jager, Agnes, Martens, John W. M., van Deurzen, Carolien H. M.
Published in Scientific reports (28.07.2022)
Published in Scientific reports (28.07.2022)
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SPEN is required for Xist upregulation during initiation of X chromosome inactivation
Robert-Finestra, Teresa, Tan, Beatrice F., Mira-Bontenbal, Hegias, Timmers, Erika, Gontan, Cristina, Merzouk, Sarra, Giaimo, Benedetto Daniele, Dossin, François, van IJcken, Wilfred F. J., Martens, John W. M., Borggrefe, Tilman, Heard, Edith, Gribnau, Joost
Published in Nature communications (01.12.2021)
Published in Nature communications (01.12.2021)
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MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer
Rodríguez-González, F. Germán, Sieuwerts, Anieta M., Smid, Marcel, Look, Maxime P., Meijer-van Gelder, Marion E., de Weerd, Vanja, Sleijfer, Stefan, Martens, John W. M., Foekens, John A.
Published in Breast cancer research and treatment (01.05.2011)
Published in Breast cancer research and treatment (01.05.2011)
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Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation
Brinkman, Arie B., Nik-Zainal, Serena, Simmer, Femke, Rodríguez-González, F. Germán, Smid, Marcel, Alexandrov, Ludmil B., Butler, Adam, Martin, Sancha, Davies, Helen, Glodzik, Dominik, Zou, Xueqing, Ramakrishna, Manasa, Staaf, Johan, Ringnér, Markus, Sieuwerts, Anieta, Ferrari, Anthony, Morganella, Sandro, Fleischer, Thomas, Kristensen, Vessela, Gut, Marta, van de Vijver, Marc J., Børresen-Dale, Anne-Lise, Richardson, Andrea L., Thomas, Gilles, Gut, Ivo G., Martens, John W. M., Foekens, John A., Stratton, Michael R., Stunnenberg, Hendrik G.
Published in Nature communications (15.04.2019)
Published in Nature communications (15.04.2019)
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Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy
Koedoot, Esmee, Wolters, Liesanne, Smid, Marcel, Stoilov, Peter, Burger, Gerhard A., Herpers, Bram, Yan, Kuan, Price, Leo S., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Published in Scientific reports (31.03.2021)
Published in Scientific reports (31.03.2021)
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Complex landscapes of somatic rearrangement in human breast cancer genomes
Lau, King Wai, Mudie, Laura J, Churcher, Carol, Stratton, Michael R, Silver, Daniel P, van 't Veer, Laura, Børresen-Dale, Anne-Lise, Stebbings, Lucy A, McBride, David J, Martens, John W. M, Simpson, Jared T, Leroy, Catherine, Russnes, Hege E. G, Latimer, Calli, Jia, Mingming, Edkins, Sarah, Natrajan, Rachael, Reis-Filho, Jorge S, Varela, Ignacio, Swerdlow, Harold, Lin, Meng-Lay, Richardson, Andrea L, Pleasance, Erin D, Sieuwerts, Anieta M, Stephens, Philip J, Futreal, P. Andrew, Greenman, Chris D, Burton, John, Langerød, Anita, Quail, Michael A, Foekens, John A, Campbell, Peter J, Teague, Jon W
Published in Nature (London) (24.12.2009)
Published in Nature (London) (24.12.2009)
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Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer
Vitale, Silvia R, Helmijr, Jean A, Gerritsen, Marjolein, Coban, Hicret, van Dessel, Lisanne F, Beije, Nick, van der Vlugt-Daane, Michelle, Vigneri, Paolo, Sieuwerts, Anieta M, Dits, Natasja, van Royen, Martin E, Jenster, Guido, Sleijfer, Stefan, Lolkema, Martijn, Martens, John W M, Jansen, Maurice P H M
Published in BMC cancer (24.03.2021)
Published in BMC cancer (24.03.2021)
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Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention
Koedoot, Esmee, van Steijn, Eline, Vermeer, Marjolein, González-Prieto, Román, Vertegaal, Alfred C O, Martens, John W M, Le Dévédec, Sylvia E, van de Water, Bob
Published in Journal of experimental & clinical cancer research (01.03.2021)
Published in Journal of experimental & clinical cancer research (01.03.2021)
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