Mcl-1 and YY1 inhibition and induction of DR5 by the BH3-mimetic Obatoclax (GX15-070) contribute in the sensitization of B-NHL cells to TRAIL apoptosis
Martínez-Paniagua, Melisa A., Baritaki, Stavroula, Huerta-Yepez, Sara, Ortiz-Navarrete, Vianney F., González-Bonilla, Cesar, Bonavida, Benjamin, Vega, Mario I.
Published in Cell cycle (Georgetown, Tex.) (15.08.2011)
Published in Cell cycle (Georgetown, Tex.) (15.08.2011)
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Journal Article
CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression
Fousek, Kristen, Watanabe, Junji, Joseph, Sujith K., George, Ann, An, Xingyue, Byrd, Tiara T., Morris, Jessica S., Luong, Annie, Martínez-Paniagua, Melisa A., Sanber, Khaled, Navai, Shoba A., Gad, Ahmed Z., Salsman, Vita S., Mathew, Pretty R., Kim, Hye Na, Wagner, Dimitrios L., Brunetti, Lorenzo, Jang, Albert, Baker, Matthew L., Varadarajan, Navin, Hegde, Meenakshi, Kim, Yong-Mi, Heisterkamp, Nora, Abdel-Azim, Hisham, Ahmed, Nabil
Published in Leukemia (01.01.2021)
Published in Leukemia (01.01.2021)
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Journal Article
Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8αβ-engineered human CD4 + T cells
Rath, Jan A, Bajwa, Gagan, Carreres, Benoit, Hoyer, Elisabeth, Gruber, Isabelle, Martínez-Paniagua, Melisa A, Yu, Yi-Ru, Nouraee, Nazila, Sadeghi, Fatemeh, Wu, Mengfen, Wang, Tao, Hebeisen, Michael, Rufer, Nathalie, Varadarajan, Navin, Ho, Ping-Chih, Brenner, Malcolm K, Gfeller, David, Arber, Caroline
Published in Science advances (01.07.2020)
Published in Science advances (01.07.2020)
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Journal Article
TIMING 2.0: high-throughput single-cell profiling of dynamic cell–cell interactions by time-lapse imaging microscopy in nanowell grids
Lu, Hengyang, Li, Jiabing, Martinez-Paniagua, Melisa A, Bandey, Irfan N, Amritkar, Amit, Singh, Harjeet, Mayerich, David, Varadarajan, Navin, Roysam, Badrinath
Published in Bioinformatics (15.02.2019)
Published in Bioinformatics (15.02.2019)
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Journal Article
Galiximab signals B-NHL cells and inhibits the activities of NF-κB-induced YY1- and snail-resistant factors: mechanism of sensitization to apoptosis by chemoimmunotherapeutic drugs
Martinez-Paniagua, Melisa A, Vega, Mario I, Huerta-Yepez, Sara, Baritaki, Stavroula, Vega, Gabriel G, Hariharan, Kandasamy, Bonavida, Benjamin
Published in Molecular cancer therapeutics (01.03.2012)
Published in Molecular cancer therapeutics (01.03.2012)
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Journal Article
A potential mechanism of rituximab-induced inhibition of tumor growth through its sensitization to tumor necrosis factor-related apoptosis-inducing ligand-expressing host cytotoxic cells
Vega, Mario I., Baritaki, Stavroula, Huerta-Yepez, Sara, Martinez-Paniagua, Melisa A., Bonavida, Benjamin
Published in Leukemia & lymphoma (01.01.2011)
Published in Leukemia & lymphoma (01.01.2011)
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Journal Article
Integrated profiling of T cells and tumor cells demonstrates metabolic adaptation essential for melanoma cell therapy
Martinez-Paniagua, Melisa A, Haymaker, Cara, Adolacion, Jay R T, An, Xingyue, Bandey, Irfan N, Creasy, Caitlin, Geiger, Tamar, Harel, Michal, Robinson, Jonathan, Nielsen, Jens B, Amritkar, Amit, Woodman, Scott, Roysam, Badrinath, Hwu, Patrick, Bernatchez, Chantale, Varadarajan, Navin
Published in The Journal of immunology (1950) (01.05.2019)
Published in The Journal of immunology (1950) (01.05.2019)
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Journal Article
Abstract 1735: Obatoclax enhances CDDP and trail-induced apoptosis in epithelial ovarian adenocarcinoma cells
Martinez-Paniagua, Melisa A., Romero-Gonzalez, Luis A., Anguiano-Hernandez, Yu Mei, Gonzalez-Torres, Carolina, Vega, Mario I.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Abstract B48: Resensitization to CDDP or trail-mediated apoptosis in ovarian cancer cells by Obatoclax
Martinez-Paniagua, Melisa A., Romero-Gonzalez, Luis A., Anguiano-Hernandez, Yu-Mei, Gonzalez-Torres, Carolina, Vega, Mario I.
Published in Cancer research (Chicago, Ill.) (01.01.2013)
Published in Cancer research (Chicago, Ill.) (01.01.2013)
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Journal Article
Abstract 766: Galiximab disrupts the dysregulated NF-κB/YY1/Snail/BclXL circuit that regulates the resistance of B-NHL cell lines: Sensitization to chemo-immunotherapeutic drugs
Vega, Gabriel G., Martinez-Paniagua, Melisa A., Huerta-Yepez, Sara, Baritaki, Stavroula, Hariharan, Kandasamy, Mayani, Hector, Vega, Mario I., Bonavida, Benjamin
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Abstract 3499: Identification of a novel mechanism by which the BH3 mimetic obatoclax sensitizes non-Hodgkin's lymphoma tumor cells to TRAIL-mediated apoptosis
Martinez-Paniagua, Melisa A., Huerta-Yepez, Sara, Baritaki, Stavroula, Gonzalez-Bonilla, Cesar R., Bonavida, Benjamin, Vega, Mario I.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
Abstract 664: Galiximab (anti-CD80 mAb) sensitizes TRAIL-resistant B-lymphoma to TRAIL-induced apoptosis via inhibition of the transcription repressor Yin Yang 1 (YY1)
Martinez-Paniagua, Melisa A., Vega, Mario I., Huerta-Yepez, Sara, Hariharan, Hari, Bonavida, Benjamin
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Abstract 4582: Regulation of Krüppel-Like Factor 4 (KLF4) expressions via Yin Yang 1 (YY1) in B Non-Hodgkin's Lymphomas (B-NHLs): KLF4 upregulation is associated with unfavorable overall survival in pediatric B-NHL
Valencia-Hipólito, Alberto, Hernandez-Atenogenes, Miriam, Vega, Gabriel G., Martinez-Paniagua, Melisa A., Aguilar-Martinez, Martha, Hernadez-Pando, Rogelio, Ramon-Garcia, Guillermo, Mayani, Hector, Martinez-Maza, Otoniel, Huerta-Yepez, Sara, Bonavida, Benjamin, Vega, Mario I.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Abstract 806: Upregulation of Krüppel-like Factor 4 (KLF-4) expression as a potential tumor progression gene product in non-Hodgkin's lymphoma
Vega, Mario I., Hernandez-Atenógenes, Miriam, Vazquez-Islas, Juan C., Martinez-Miguel, Bernardo, Martinez-Paniagua, Melisa A., Antonio-Andres, Gabriela, Rivera-Pazos, Clara M., Maldonado-Valenzuela, Altagracia, Martinez-Maza, Otoniel, Huerta-Yepez, Sara, Bonavida, Benjamin
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Rituximab Sensitizes TRAIL-Resistant B-NHL Lines to Apoptosis by Both TRAIL and Fully Humanized Antibodies Targeting TRAIL-R1 (Mapatumumab) and TRAIL-R2 (Lexatumumab)
Vega, Mario I., Huerta-Yepez, Sara, Baritaki, Stavroula, Martinez-Paniagua, Melisa A., Gonzalez-Bonilla, Cesar R., Bonavida, Benjamin
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Journal Article
Rituximab-Mediated Inhibition of the p38 MAPK and NF-κB Survival Pathways In Vitro and Validation in Nude Mice Bearing the Raji B-NHL Tumor
Vega, Mario I., Huerta-Yepez, Sara, Martinez-Paniagua, Melisa A., Bonilla, Cesar G., Bonavida, Benjamin
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
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Journal Article
Cytotoxicity of Genetically Engineered Fusion Protein with CD154 Peptide Mimetic (OmpC-CD154p) on B-NHL Cell Lines
Martinez-Miguel, Bernardo, Martinez-Paniagua, Melisa A., Huerta-Yepez, Sara, Hernandez-Pando, Rogelio, Gonzalez-Bonilla, Cesar R., Bonavida, Benjamin, Vega, Mario I.
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Journal Article
Direct and Enhanced Cytotoxicity of the Bcl-2 Family Inhibitor GX15-070 on Rituximab-Sensitive and Rituximab-Resistant B-NHL Clones
Martinez-Paniagua, Melisa A., Vega, Mario I., Huerta-Yepez, Sara, Martinez-Miguel, Bernardo, Hernandez-Pando, Rogelio, Gonzalez-Bonilla, Cesar R., Bonavida, Benjamin
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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