The impact of non-additive genetic associations on age-related complex diseases
Guindo-Martínez, Marta, Amela, Ramon, Bonàs-Guarch, Silvia, Puiggròs, Montserrat, Salvoro, Cecilia, Miguel-Escalada, Irene, Carey, Caitlin E., Cole, Joanne B., Rüeger, Sina, Atkinson, Elizabeth, Leong, Aaron, Sanchez, Friman, Ramon-Cortes, Cristian, Ejarque, Jorge, Palmer, Duncan S., Kurki, Mitja, Aragam, Krishna, Florez, Jose C., Badia, Rosa M., Mercader, Josep M., Torrents, David
Published in Nature communications (23.04.2021)
Published in Nature communications (23.04.2021)
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A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability
Sadler, Jessica B. A., Wenzel, Dawn M., Williams, Lauren K., Guindo-Martínez, Marta, Alam, Steven L., Mercader, Josep M., Torrents, David, Ullman, Katharine S., Sundquist, Wesley I., Martin-Serrano, Juan
Published in Proceedings of the National Academy of Sciences - PNAS (18.09.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (18.09.2018)
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Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Bonàs-Guarch, Sílvia, Guindo-Martínez, Marta, Miguel-Escalada, Irene, Grarup, Niels, Sebastian, David, Rodriguez-Fos, Elias, Sánchez, Friman, Planas-Fèlix, Mercè, Cortes-Sánchez, Paula, González, Santi, Timshel, Pascal, Pers, Tune H., Morgan, Claire C., Moran, Ignasi, Atla, Goutham, González, Juan R., Puiggros, Montserrat, Martí, Jonathan, Andersson, Ehm A., Díaz, Carlos, Badia, Rosa M., Udler, Miriam, Leong, Aaron, Kaur, Varindepal, Flannick, Jason, Jørgensen, Torben, Linneberg, Allan, Jørgensen, Marit E., Witte, Daniel R., Christensen, Cramer, Brandslund, Ivan, Appel, Emil V., Scott, Robert A., Luan, Jian’an, Langenberg, Claudia, Wareham, Nicholas J., Pedersen, Oluf, Zorzano, Antonio, Florez, Jose C, Hansen, Torben, Ferrer, Jorge, Mercader, Josep Maria, Torrents, David
Published in Nature communications (22.01.2018)
Published in Nature communications (22.01.2018)
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Polymorphic Inversions Underlie the Shared Genetic Susceptibility of Obesity-Related Diseases
González, Juan R., Ruiz-Arenas, Carlos, Cáceres, Alejandro, Morán, Ignasi, López-Sánchez, Marcos, Alonso, Lorena, Tolosana, Ignacio, Guindo-Martínez, Marta, Mercader, Josep M., Esko, Tonu, Torrents, David, González, Josefa, Pérez-Jurado, Luis A.
Published in American journal of human genetics (04.06.2020)
Published in American journal of human genetics (04.06.2020)
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Altered Circulating miRNA Expression Profile in Pregestational and Gestational Obesity
Carreras-Badosa, Gemma, Bonmatí, Alexandra, Ortega, Francisco-Jose, Mercader, Josep-Maria, Guindo-Martínez, Marta, Torrents, David, Prats-Puig, Anna, Martinez-Calcerrada, Jose-Maria, Platero-Gutierrez, Estíbaliz, De Zegher, Francis, Ibáñez, Lourdes, Fernandez-Real, Jose-Manuel, Lopez-Bermejo, Abel, Bassols, Judit
Published in The journal of clinical endocrinology and metabolism (01.11.2015)
Published in The journal of clinical endocrinology and metabolism (01.11.2015)
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FGL1 as a modulator of plasma D‐dimer levels: Exome‐wide marker analysis of plasma tPA, PAI‐1, and D‐dimer
Thibord, Florian, Song, Ci, Pattee, Jack, Rodriguez, Benjamin A.T., Chen, Ming‐Huei, O’Donnell, Christopher J., Kleber, Marcus E., Delgado, Graciela E., Guo, Xiuqing, Yao, Jie, Taylor, Kent D., Ozel, Ayse Bilge, Brody, Jennifer A., McKnight, Barbara, Gyorgy, Beata, Simonsick, Eleanor, Leonard, Hampton L., Carrasquilla, Germán D., Guindo‐Martinez, Marta, Silveira, Angela, Temprano‐Sagrera, Gerard, Yanek, Lisa R., Becker, Diane M., Mathias, Rasika A., Becker, Lewis C., Raffield, Laura M., Kilpeläinen, Tuomas O., Grarup, Niels, Pedersen, Oluf, Hansen, Torben, Linneberg, Allan, Hamsten, Anders, Watkins, Hugh, Sabater‐Lleal, Maria, Nalls, Mike A., Trégouët, David‐Alexandre, Morange, Pierre‐Emmanuel, Psaty, Bruce M., Tracy, Russel P., Smith, Nicholas L., Desch, Karl C., Cushman, Mary, Rotter, Jerome I., Vries, Paul S., Pankratz, Nathan D., Folsom, Aaron R., Morrison, Alanna C., März, Winfried, Tang, Weihong, Johnson, Andrew D.
Published in Journal of thrombosis and haemostasis (01.08.2021)
Published in Journal of thrombosis and haemostasis (01.08.2021)
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Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Bonàs Guarch, Sílvia, Guindo-Martínez, Marta, Miguel-Escalada, Irene, Grarup, Niels, Sebastián Muñoz, David, Rodriguez-Fos, Elias, Sánchez, Friman, Planas-Fèlix, Mercè, Cortes-Sánchez, Paula, González, Santi, Timshel, Pascal, Pers, Tune H, Morgan, Claire C, Moran, Ignasi, Atla, Goutham, González, Juan Ramón, Puiggros, Montserrat, Martí, Jonathan, Andersson, Ehm A, Díaz, Carlos, Badia, Rosa M, Udler, Miriam, Leong, Aaron, Kaur, Varindepal, Flannick, Jason, Jørgensen, Torben, Linneberg, Allan, Jørgensen, Marit E, Witte, Daniel R, Christensen, Cramer, Brandslund, Ivan, Appel, Emil V, Scott, Robert A, Luan, Jian'an, Langenberg, Claudia, Wareham, Nicholas J, Pedersen, Oluf, Zorzano Olarte, Antonio, Florez, Jose C, Hansen, Torben
Published in Nature communications (30.05.2018)
Published in Nature communications (30.05.2018)
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Dysregulation of Placental miRNA in Maternal Obesity Is Associated With Pre- and Postnatal Growth
Carreras-Badosa, Gemma, Bonmatí, Alexandra, Ortega, Francisco-Jose, Mercader, Josep-Maria, Guindo-Martínez, Marta, Torrents, David, Prats-Puig, Anna, Martinez-Calcerrada, Jose-Maria, de Zegher, Francis, Ibáñez, Lourdes, Fernandez-Real, Jose-Manuel, Lopez-Bermejo, Abel, Bassols, Judit
Published in The journal of clinical endocrinology and metabolism (01.07.2017)
Published in The journal of clinical endocrinology and metabolism (01.07.2017)
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TIGER: The gene expression regulatory variation landscape of human pancreatic islets
Alonso, Lorena, Piron, Anthony, Morán, Ignasi, Guindo-Martínez, Marta, Bonàs-Guarch, Sílvia, Atla, Goutham, Miguel-Escalada, Irene, Royo, Romina, Puiggròs, Montserrat, Garcia-Hurtado, Xavier, Suleiman, Mara, Marselli, Lorella, Esguerra, Jonathan L.S., Turatsinze, Jean-Valéry, Torres, Jason M., Nylander, Vibe, Chen, Ji, Eliasson, Lena, Defrance, Matthieu, Amela, Ramon, Mulder, Hindrik, Gloyn, Anna L., Groop, Leif, Marchetti, Piero, Eizirik, Decio L., Ferrer, Jorge, Mercader, Josep M., Cnop, Miriam, Torrents, David
Published in Cell reports (Cambridge) (12.10.2021)
Published in Cell reports (Cambridge) (12.10.2021)
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Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes
O'Connor, Mark J, Schroeder, Philip, Huerta-Chagoya, Alicia, Cortés-Sánchez, Paula, Bonàs-Guarch, Silvía, Guindo-Martínez, Marta, Cole, Joanne B, Kaur, Varinderpal, Torrents, David, Veerapen, Kumar, Grarup, Niels, Kurki, Mitja, Rundsten, Carsten F, Pedersen, Oluf, Brandslund, Ivan, Linneberg, Allan, Hansen, Torben, Leong, Aaron, Florez, Jose C, Mercader, Josep M
Published in Diabetes (New York, N.Y.) (01.03.2022)
Published in Diabetes (New York, N.Y.) (01.03.2022)
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Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort
Galván-Femenía, Iván, Obón-Santacana, Mireia, Piñeyro, David, Guindo-Martinez, Marta, Duran, Xavier, Carreras, Anna, Pluvinet, Raquel, Velasco, Juan, Ramos, Laia, Aussó, Susanna, Mercader, J M, Puig, Lluis, Perucho, Manuel, Torrents, David, Moreno, Victor, Sumoy, Lauro, de Cid, Rafael
Published in Journal of medical genetics (01.11.2018)
Published in Journal of medical genetics (01.11.2018)
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OS-072-YI Identifying patterns of steatotic liver disease severity: a multiomic analysis of 834 distinct omics features from healthy to end-stage liver disease in 854 individuals
Hansen, Johanne Kragh, Nishijima, Suguru, Schierwagen, Robert, Holm, Louise Aas, Sulek, Karolina, Suvitaival, Tommi, Pedersen, Julie Steen, Israelsen, Mads, Torp, Nikolaj, Johansen, Stine, Fonvig, Cilius, Martínez, Marta Guindo, Stinson, Sara, Huang, Yun, Jensen, Rasmus Tanderup, Stankevic, Evelina, Kuhn, Michael, Keller, Marisa Isabell, Van Espen, Lore, Alvarez-Silva, Camila, Villesen, Ida Falk, Thorhauge, Katrine, Andersen, Peter, Lindvig, Katrine, de Zawadzki, Andressa, Brol, Maximilian Joseph, Nielsen, Trine, Brøns, Charlotte, Juel, Helene Baek, Niu, Lili, Holm, Jens-Christian, Bendtsen, Flemming, Karsdal, Morten, Mann, Matthias, Matthijnssens, Jelle, Legido-Quigly, Cristina, Trebicka, Jonel, Arumugam, Manimozhiyan, Thiele, Maja, Jensen, Lars Juhl, Bork, Peer, Hansen, Torben, Krag, Aleksander
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
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Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Bonàs Guarch, Sílvia, Guindo-Martínez, Marta, Miguel-Escalada, Irene, Grarup, Niels, Sebastián Muñoz, David, Rodriguez-Fos, Elias, Sánchez, Friman, Planas-Fèlix, Mercè, Cortes-Sánchez, Paula, González, Santi, Timshel, Pascal, Pers, Tune H, Morgan, Claire C, Moran, Ignasi, Atla, Goutham, González, Juan Ramón, Puiggros, Montserrat, Martí, Jonathan, Andersson, Ehm A, Díaz, Carlos, Badia, Rosa M, Udler, Miriam, Leong, Aaron, Kaur, Varindepal, Flannick, Jason, Jørgensen, Torben, Linneberg, Allan, Jørgensen, Marit E, Witte, Daniel R, Christensen, Cramer, Brandslund, Ivan, Appel, Emil V, Scott, Robert A, Luan, Jian'an, Langenberg, Claudia, Wareham, Nicholas J, Pedersen, Oluf, Zorzano Olarte, Antonio, Florez, Jose C, Hansen, Torben
Published in Nature communications (22.01.2018)
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Published in Nature communications (22.01.2018)
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Publisher Correction: Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Bonàs-Guarch, Sílvia, Guindo-Martínez, Marta, Miguel-Escalada, Irene, Grarup, Niels, Sebastian, David, Rodriguez-Fos, Elias, Sánchez, Friman, Planas-Fèlix, Mercè, Cortes-Sánchez, Paula, González, Santi, Timshel, Pascal, Pers, Tune H., Morgan, Claire C., Moran, Ignasi, Atla, Goutham, González, Juan R., Puiggros, Montserrat, Martí, Jonathan, Andersson, Ehm A., Díaz, Carlos, Badia, Rosa M., Udler, Miriam, Leong, Aaron, Kaur, Varindepal, Flannick, Jason, Jørgensen, Torben, Linneberg, Allan, Jørgensen, Marit E., Witte, Daniel R., Christensen, Cramer, Brandslund, Ivan, Appel, Emil V., Scott, Robert A., Luan, Jian’an, Langenberg, Claudia, Wareham, Nicholas J., Pedersen, Oluf, Zorzano, Antonio, Florez, Jose C, Hansen, Torben, Ferrer, Jorge, Mercader, Josep Maria, Torrents, David
Published in Nature communications (30.05.2018)
Published in Nature communications (30.05.2018)
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Erratum: Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium
Fernández-Rhodes, Lindsay, Graff, Mariaelisa, Buchanan, Victoria L, Justice, Anne E, Highland, Heather M, Guo, Xiuqing, Zhu, Wanying, Chen, Hung-Hsin, Young, Kristin L, Adhikari, Kaustubh, Palmer, Nicholette D, Below, Jennifer E, Bradfield, Jonathan, Pereira, Alexandre C, Glover, LáShauntá, Kim, Daeeun, Lilly, Adam G, Shrestha, Poojan, Thomas, Alvin G, Zhang, Xinruo, Chen, Minhui, Chiang, Charleston W K, Pulit, Sara, Horimoto, Andrea, Krieger, Jose E, Guindo-Martínez, Marta, Preuss, Michael, Schumann, Claudia, Smit, Roelof A J, Torres-Mejía, Gabriela, Acuña-Alonzo, Victor, Bedoya, Gabriel, Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Gallo, Carla, González-José, Rolando, Poletti, Giovanni, Rothhammer, Francisco, Hakonarson, Hakon, Igo, Robert, Adler, Sharon G, Iyengar, Sudha K, Nicholas, Susanne B, Gogarten, Stephanie M, Isasi, Carmen R, Papnicolaou, George, Stilp, Adrienne M, Qi, Qibin, Kho, Minjung, Smith, Jennifer A, Langefeld, Carl D, Wagenknecht, Lynne, Mckean-Cowdin, Roberta, Gao, Xiaoyi Raymond, Nousome, Darryl, Conti, David V, Feng, Ye, Allison, Matthew A, Arzumanyan, Zorayr, Buchanan, Thomas A, Chen, Yii-Der Ida, Genter, Pauline M, Goodarzi, Mark O, Hai, Yang, Hsueh, Willa, Ipp, Eli, Kandeel, Fouad R, Lam, Kelvin, Li, Xiaohui, Nadler, Jerry L, Raffel, Leslie J, Roll, Kathryn, Sandow, Kevin, Tan, Jingyi, Taylor, Kent D, Xiang, Anny H, Yao, Jie, Audirac-Chalifour, Astride, Peralta Romero, Jose de Jesus, Hartwig, Fernando, Horta, Bernando, Blangero, John, Curran, Joanne E, Duggirala, Ravindranath, Lehman, Donna E, Puppala, Sobha, Fejerman, Laura, John, Esther M, Aguilar-Salinas, Carlos, Burtt, Noël P, Florez, Jose C, García-Ortíz, Humberto, González-Villalpando, Clicerio, Mercader, Josep, Orozco, Lorena, Tusié-Luna, Teresa, Blanco, Estela, Gahagan, Sheila, Cox, Nancy J, Hanis, Craig
Published in HGG advances (12.01.2023)
Published in HGG advances (12.01.2023)
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Whole-genome sequencing reveals host factors underlying critical COVID-19
Kousathanas, Athanasios, Pairo-Castineira, Erola, Rawlik, Konrad, Stuckey, Alex, Odhams, Christopher A., Walker, Susan, Russell, Clark D., Malinauskas, Tomas, Wu, Yang, Millar, Jonathan, Shen, Xia, Elliott, Katherine S., Griffiths, Fiona, Oosthuyzen, Wilna, Morrice, Kirstie, Keating, Sean, Wang, Bo, Rhodes, Daniel, Klaric, Lucija, Zechner, Marie, Parkinson, Nick, Siddiq, Afshan, Goddard, Peter, Donovan, Sally, Maslove, David, Nichol, Alistair, Semple, Malcolm G., Zainy, Tala, Maleady-Crowe, Fiona, Todd, Linda, Salehi, Shahla, Knight, Julian, Elgar, Greg, Chan, Georgia, Arumugam, Prabhu, Patch, Christine, Rendon, Augusto, Bentley, David, Kingsley, Clare, Kosmicki, Jack A., Horowitz, Julie E., Baras, Aris, Abecasis, Goncalo R., Ferreira, Manuel A. R., Justice, Anne, Mirshahi, Tooraj, Oetjens, Matthew, Rader, Daniel J., Ritchie, Marylyn D., Verma, Anurag, Fowler, Tom A., Shankar-Hari, Manu, Summers, Charlotte, Hinds, Charles, Horby, Peter, Ling, Lowell, McAuley, Danny, Montgomery, Hugh, Openshaw, Peter J. M., Elliott, Paul, Walsh, Timothy, Tenesa, Albert, Fawkes, Angie, Murphy, Lee, Rowan, Kathy, Ponting, Chris P., Vitart, Veronique, Wilson, James F., Yang, Jian, Bretherick, Andrew D., Scott, Richard H., Hendry, Sara Clohisey, Moutsianas, Loukas, Law, Andy, Caulfield, Mark J., Baillie, J. Kenneth
Published in Nature (London) (2022)
Published in Nature (London) (2022)
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A first update on mapping the human genetic architecture of COVID-19
Pathak, Gita A., Karjalainen, Juha, Stevens, Christine, Neale, Benjamin M., Daly, Mark, Ganna, Andrea, Andrews, Shea J., Kanai, Masahiro, Cordioli, Mattia, Polimanti, Renato, Harerimana, Nadia, Pirinen, Matti, Liao, Rachel G., Chwialkowska, Karolina, Trankiem, Amy, Balaconis, Mary K., Nguyen, Huy, Solomonson, Matthew, Veerapen, Kumar, Wolford, Brooke, Roberts, Genevieve, Park, Danny, Ball, Catherine A., Coignet, Marie, McCurdy, Shannon, Knight, Spencer, Partha, Raghavendran, Rhead, Brooke, Zhang, Miao, Berkowitz, Nathan, Gaddis, Michael, Noto, Keith, Ruiz, Luong, Pavlovic, Milos, Hong, Eurie L., Rand, Kristin, Girshick, Ahna, Guturu, Harendra, Baltzell, Asher Haug, Niemi, Mari E. K., Rahmouni, Souad, Guntz, Julien, Beguin, Yves, Pigazzini, Sara, Nkambule, Lindokuhle, Georges, Michel, Moutschen, Michel, Misset, Benoit, Darcis, Gilles, Guiot, Julien, Azarzar, Samira, Gofflot, Stéphanie, Claassen, Sabine, Malaise, Olivier, Huynen, Pascale, Meuris, Christelle, Thys, Marie, Jacques, Jessica, Léonard, Philippe, Frippiat, Frederic, Giot, Jean-Baptiste, Sauvage, Anne-Sophie, Frenckell, Christian Von, Belhaj, Yasmine, Lambermont, Bernard, Nakanishi, Tomoko, Morrison, David R., Mooser, Vincent, Richards, J. Brent, Butler-Laporte, Guillaume, Forgetta, Vincenzo, Li, Rui, Ghosh, Biswarup, Laurent, Laetitia, Belisle, Alexandre, Henry, Danielle, Abdullah, Tala, Adeleye, Olumide, Mamlouk, Noor, Kimchi, Nofar, Afrasiabi, Zaman, Rezk, Nardin, Vulesevic, Branka, Bouab, Meriem, Guzman, Charlotte, Petitjean, Louis, Tselios, Chris, Xue, Xiaoqing, Afilalo, Jonathan, Afilalo, Marc, Oliveira, Maureen, Brenner, Bluma, Brassard, Nathalie, Durand, Madeleine, Schurr, Erwin, Lepage, Pierre, Ragoussis, Jiannis, Auld, Daniel, Chassé, Michaël, Kaufmann, Daniel E.
Published in Nature (London) (04.08.2022)
Published in Nature (London) (04.08.2022)
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A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma
Chinnaswamy, Sreedhar, Wardzynska, Aleksandra, Pawelczyk, Malgorzata, Makowska, Joanna, Skaaby, Tea, Mercader, Josep M., Ahluwalia, Tarunveer S., Grarup, Niels, Guindo-Martinez, Marta, Bisgaard, Hans, Torrents, David, Linneberg, Allan, Bønnelykke, Klaus, Kowalski, Marek L.
Published in Scientific reports (05.09.2017)
Published in Scientific reports (05.09.2017)
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The impact of non-additive genetic associations on age-related complex diseases
Guindo-Martínez, Marta, Amela, Ramon, Bonàs-Guarch, Sílvia, Puiggròs, Montserrat, Salvoro, Cecilia, Miguel-Escalada, Irene, Carey, Caitlin E, Cole, Joanne B, Rüeger, Sina, Atkinson, Elizabeth, Leong, Aaron, Sánchez, Friman, Ramon-Cortes, Cristian, Ejarque, Jorge, Palmer, Duncan S, Kurki, Mitja, Aragam, Krishna, Florez, Jose C, Badia, Rosa M, Mercader, Josep M, Torrents, David
Published in bioRxiv (14.05.2020)
Published in bioRxiv (14.05.2020)
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Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Bonàs-Guarch, Sílvia, Guindo-Martínez, Marta, Miguel-Escalada, Irene, Grarup, Niels, Sebastian, David, Rodriguez-Fos, Elias, Sánchez, Friman, Planas-Fèlix, Mercè, Cortes-Sánchez, Paula, González, Santi, Timshel, Pascal, Pers, Tune H, Morgan, Claire C, Moran, Ignasi, Atla, Goutham, González, Juan R, Puiggros, Montserrat, Martí, Jonathan, Andersson, Ehm A, Díaz, Carlos, Badia, Rosa M, Udler, Miriam, Leong, Aaron, Kaur, Varindepal, Flannick, Jason, Jorgensen, Torben, Linneberg, Allan, Jorgensen, Marit E, Witte, Daniel R, Christensen, Cramer, Brandslund, Ivan, Appel, Emil V, Scott, Robert A, Luan, Jian' an, Langenberg, Claudia, Wareham, Nicholas J, Pedersen, Oluf, Zorzano, Antonio, Florez, Jose C, Hansen, Torben, Ferrer, Jorge, Mercader, Josep M, Torrents, David
Year of Publication 22.01.2018
Year of Publication 22.01.2018
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