Influence of CYP2D6, CYP3A4, CYP3A5 and ABCB1 Polymorphisms on Pharmacokinetics and Safety of Aripiprazole in Healthy Volunteers
Belmonte, Carmen, Ochoa, Dolores, Román, Manuel, Saiz‐Rodríguez, Miriam, Wojnicz, Aneta, Gómez‐Sánchez, Clara Isabel, Martín‐Vílchez, Samuel, Abad‐Santos, Francisco
Published in Basic & clinical pharmacology & toxicology (01.06.2018)
Published in Basic & clinical pharmacology & toxicology (01.06.2018)
Get full text
Journal Article
First-in-human phase I clinical trial of a TLR4-binding DNA aptamer, ApTOLL: Safety and pharmacokinetics in healthy volunteers
Hernández-Jiménez, Macarena, Martín-Vílchez, Samuel, Ochoa, Dolores, Mejía-Abril, Gina, Román, Manuel, Camargo-Mamani, Paola, Luquero-Bueno, Sergio, Jilma, Bernd, Moro, María A., Fernández, Gerónimo, Piñeiro, David, Ribó, Marc, González, Víctor M., Lizasoain, Ignacio, Abad-Santos, Francisco
Published in Molecular therapy. Nucleic acids (14.06.2022)
Published in Molecular therapy. Nucleic acids (14.06.2022)
Get full text
Journal Article
Impact of polymorphisms in transporter and metabolizing enzyme genes on olanzapine pharmacokinetics and safety in healthy volunteers
Zubiaur, Pablo, Soria-Chacartegui, Paula, Koller, Dora, Navares-Gómez, Marcos, Ochoa, Dolores, Almenara, Susana, Saiz-Rodríguez, Miriam, Mejía-Abril, Gina, Villapalos-García, Gonzalo, Román, Manuel, Martín-Vílchez, Samuel, Abad-Santos, Francisco
Published in Biomedicine & pharmacotherapy (01.01.2021)
Published in Biomedicine & pharmacotherapy (01.01.2021)
Get full text
Journal Article
NAT2 phenotype alters pharmacokinetics of rivaroxaban in healthy volunteers
Villapalos-García, Gonzalo, Zubiaur, Pablo, Ochoa, Dolores, Soria-Chacartegui, Paula, Navares-Gómez, Marcos, Matas, Miriam, Mejía-Abril, Gina, Casajús-Rey, Ana, Campodónico, Diana, Román, Manuel, Martín-Vílchez, Samuel, Candau-Ramos, Carmen, Aldama-Martín, Marina, Abad-Santos, Francisco
Published in Biomedicine & pharmacotherapy (01.09.2023)
Published in Biomedicine & pharmacotherapy (01.09.2023)
Get full text
Journal Article
Impact of polymorphisms in CYP and UGT enzymes and ABC and SLCO1B1 transporters on the pharmacokinetics and safety of desvenlafaxine
Calleja, Sofía, Zubiaur, Pablo, Ochoa, Dolores, Villapalos-García, Gonzalo, Mejia-Abril, Gina, Soria-Chacartegui, Paula, Navares-Gómez, Marcos, de Miguel, Alejandro, Román, Manuel, Martín-Vílchez, Samuel, Abad-Santos, Francisco
Published in Frontiers in pharmacology (02.02.2023)
Published in Frontiers in pharmacology (02.02.2023)
Get full text
Journal Article
Genetic Variation in CYP2D6, UGT1A4, SLC6A2 and SLCO1B1 Alters the Pharmacokinetics and Safety of Mirabegron
Soria-Chacartegui, Paula, Cendoya-Ramiro, Patricia, González-Iglesias, Eva, Martín-Vílchez, Samuel, Rodríguez-Lopez, Andrea, Mejía-Abril, Gina, Román, Manuel, Luquero-Bueno, Sergio, Ochoa, Dolores, Abad-Santos, Francisco
Published in Pharmaceutics (17.08.2024)
Published in Pharmaceutics (17.08.2024)
Get full text
Journal Article
Effects of Cytochrome P450 and Transporter Polymorphisms on the Bioavailability and Safety of Dutasteride and Tamsulosin
Villapalos-García, Gonzalo, Zubiaur, Pablo, Navares-Gómez, Marcos, Saiz-Rodríguez, Miriam, Mejía-Abril, Gina, Martín-Vílchez, Samuel, Román, Manuel, Ochoa, Dolores, Abad-Santos, Francisco
Published in Frontiers in pharmacology (07.10.2021)
Published in Frontiers in pharmacology (07.10.2021)
Get full text
Journal Article
SLCO1B1 Phenotype and CYP3A5 Polymorphism Significantly Affect Atorvastatin Bioavailability
Zubiaur, Pablo, Benedicto, Maria Dolores, Villapalos-García, Gonzalo, Navares-Gómez, Marcos, Mejía-Abril, Gina, Román, Manuel, Martín-Vílchez, Samuel, Ochoa, Dolores, Abad-Santos, Francisco
Published in Journal of personalized medicine (13.03.2021)
Published in Journal of personalized medicine (13.03.2021)
Get full text
Journal Article
The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells
Martín‐Vílchez, Samuel, Sanz‐Cameno, Paloma, Rodríguez‐Muñoz, Yolanda, Majano, Pedro L., Molina‐Jiménez, Francisca, López‐Cabrera, Manuel, Moreno‐Otero, Ricardo, Lara‐Pezzi, Enrique
Published in Hepatology (Baltimore, Md.) (01.06.2008)
Published in Hepatology (Baltimore, Md.) (01.06.2008)
Get full text
Journal Article
Polymorphism of Drug Transporters, Rather Than Metabolizing Enzymes, Conditions the Pharmacokinetics of Rasagiline
Zubiaur, Pablo, Matas, Miriam, Martín-Vílchez, Samuel, Soria-Chacartegui, Paula, Villapalos-García, Gonzalo, Figueiredo-Tor, Laura, Calleja, Sofía, Navares-Gómez, Marcos, de Miguel, Alejandro, Novalbos, Jesús, Mejía-Abril, Gina, Luquero-Bueno, Sergio, Román, Manuel, Ochoa, Dolores, Abad-Santos, Francisco
Published in Pharmaceutics (21.09.2022)
Published in Pharmaceutics (21.09.2022)
Get full text
Journal Article
Interferon-related genetic markers of necroinflammatory activity in chronic hepatitis C
López-Rodríguez, Rosario, Hernández-Bartolomé, Ángel, Borque, María Jesús, Rodríguez-Muñoz, Yolanda, Martín-Vílchez, Samuel, García-Buey, Luisa, González-Moreno, Leticia, Real-Martínez, Yolanda, Muñoz de Rueda, Paloma, Salmerón, Javier, Vidal-Castiñeira, José Ramón, López-Larrea, Carlos, Rodrigo, Luis, Moreno-Otero, Ricardo, Sanz-Cameno, Paloma
Published in PloS one (12.07.2017)
Published in PloS one (12.07.2017)
Get full text
Journal Article
Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride
Villapalos-García, Gonzalo, Zubiaur, Pablo, Marián-Revilla, Cristina, Soria-Chacartegui, Paula, Navares-Gómez, Marcos, Mejía-Abril, Gina, Rodríguez-Lopez, Andrea, González-Iglesias, Eva, Martín-Vílchez, Samuel, Román, Manuel, Ochoa, Dolores, Abad-Santos, Francisco
Published in Journal of personalized medicine (01.10.2023)
Published in Journal of personalized medicine (01.10.2023)
Get full text
Journal Article
Intrahepatic angiopoietin‐2 correlates with chronic hepatitis C progression and is induced in hepatitis C virus replicon systems
Hernández‐Bartolomé, Ángel, López‐Rodríguez, Rosario, García‐Buey, Luisa, Martín‐Vílchez, Samuel, Rodríguez‐Muñoz, Yolanda, Borque, María Jesús, González‐Moreno, Leticia, Real‐Martínez, Yolanda, Mendoza‐Ridruejo, Jorge, Martín‐Pérez, Elena, Moreno‐Otero, Ricardo, Sanz‐Cameno, Paloma
Published in Liver international (01.08.2017)
Published in Liver international (01.08.2017)
Get full text
Journal Article
Expression of pituitary tumor–transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)‐associated liver diseases: Evidence for an HBV X protein–mediated inhibition of PTTG1 ubiquitination and degradation
Molina‐Jiménez, Francisca, Benedicto, Ignacio, Murata, Miki, Martín‐Vílchez, Samuel, Seki, Toshihito, Antonio Pintor‐Toro, José, Tortolero, María, Moreno‐Otero, Ricardo, Okazaki, Kazuichi, Koike, Kazuhiko, Barbero, José Luchi, Matsuzaki, Koichi, Majano, Pedro L., López‐Cabrera, Manuel
Published in Hepatology (Baltimore, Md.) (01.03.2010)
Published in Hepatology (Baltimore, Md.) (01.03.2010)
Get full text
Journal Article
Inhibition of tyrosine kinase receptor Tie2 reverts HCV-induced hepatic stellate cell activation
Martín-Vílchez, Samuel, Rodríguez-Muñoz, Yolanda, López-Rodríguez, Rosario, Hernández-Bartolomé, Borque-Iñurrita, María Jesús, Molina-Jiménez, Francisca, García-Buey, Luisa, Moreno-Otero, Ricardo, Sanz-Cameno, Paloma
Published in PloS one (10.10.2014)
Published in PloS one (10.10.2014)
Get full text
Journal Article
Angiopoietin-2 Serum Levels Improve Noninvasive Fibrosis Staging in Chronic Hepatitis C: A Fibrogenic-Angiogenic Link
Hernández-Bartolomé, Angel, López-Rodríguez, Rosario, Rodríguez-Muñoz, Yolanda, Martín-Vílchez, Samuel, Borque, María Jesús, García-Buey, Luisa, González-Moreno, Leticia, Real, Yolanda, Moreno-Otero, Ricardo, Sanz-Cameno, Paloma
Published in PloS one (18.06.2013)
Published in PloS one (18.06.2013)
Get full text
Journal Article
Hepatitis B Virus Promotes Angiopoietin-2 Expression in Liver Tissue: Role of HBV X Protein
Sanz-Cameno, Paloma, Martin-Vilchez, Samuel, Lara-Pezzi, Enrique, Borque, Maria J, Salmeron, Javier, Munoz de Rueda, Paloma, Solis, Jose A, Lopez-Cabrera, Manuel, Moreno-Otero, Ricardo
Published in The American journal of pathology (01.10.2006)
Published in The American journal of pathology (01.10.2006)
Get full text
Journal Article
Preliminary evidence of sustained expression of angiopoietin-2 during monocyte differentiation in chronic hepatitis C
Rodríguez-Muñoz, Yolanda, Martín-Vílchez, Samuel, López-Rodríguez, Rosario, Hernández-Bartolomé, Ángel, García-Buey, Luisa, Borque, María J., Moreno-Otero, Ricardo, Sanz-Cameno, Paloma
Published in Liver international (01.07.2013)
Published in Liver international (01.07.2013)
Get full text
Journal Article
Enhanced intrahepatic inducible nitric oxide synthase expression and nitrotyrosine accumulation in primary biliary cirrhosis and autoimmune hepatitis
Sanz-Cameno, Paloma, Medina, Jesús, Garcı́a-Buey, Luisa, Garcı́a-Sánchez, Asunción, Borque, Marı́a J, Martı́n-Vı́lchez, Samuel, Gamallo, Carlos, Jones, E.Anthony, Moreno-Otero, Ricardo
Published in Journal of hepatology (01.12.2002)
Published in Journal of hepatology (01.12.2002)
Get full text
Journal Article