Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
Hammond, Timothy R., Dufort, Connor, Dissing-Olesen, Lasse, Giera, Stefanie, Young, Adam, Wysoker, Alec, Walker, Alec J., Gergits, Frederick, Segel, Michael, Nemesh, James, Marsh, Samuel E., Saunders, Arpiar, Macosko, Evan, Ginhoux, Florent, Chen, Jinmiao, Franklin, Robin J.M., Piao, Xianhua, McCarroll, Steven A., Stevens, Beth
Published in Immunity (Cambridge, Mass.) (15.01.2019)
Published in Immunity (Cambridge, Mass.) (15.01.2019)
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Journal Article
iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
Abud, Edsel M., Ramirez, Ricardo N., Martinez, Eric S., Healy, Luke M., Nguyen, Cecilia H.H., Newman, Sean A., Yeromin, Andriy V., Scarfone, Vanessa M., Marsh, Samuel E., Fimbres, Cristhian, Caraway, Chad A., Fote, Gianna M., Madany, Abdullah M., Agrawal, Anshu, Kayed, Rakez, Gylys, Karen H., Cahalan, Michael D., Cummings, Brian J., Antel, Jack P., Mortazavi, Ali, Carson, Monica J., Poon, Wayne W., Blurton-Jones, Mathew
Published in Neuron (Cambridge, Mass.) (19.04.2017)
Published in Neuron (Cambridge, Mass.) (19.04.2017)
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Journal Article
The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function
Marsh, Samuel E., Abud, Edsel M., Lakatos, Anita, Karimzadeh, Alborz, Yeung, Stephen T., Davtyan, Hayk, Fote, Gianna M., Lau, Lydia, Weinger, Jason G., Lane, Thomas E., Inlay, Matthew A., Poon, Wayne W., Blurton-Jones, Mathew
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2016)
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Journal Article
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain
Marsh, Samuel E., Walker, Alec J., Kamath, Tushar, Dissing-Olesen, Lasse, Hammond, Timothy R., de Soysa, T. Yvanka, Young, Adam M. H., Murphy, Sarah, Abdulraouf, Abdulraouf, Nadaf, Naeem, Dufort, Connor, Walker, Alicia C., Lucca, Liliana E., Kozareva, Velina, Vanderburg, Charles, Hong, Soyon, Bulstrode, Harry, Hutchinson, Peter J., Gaffney, Daniel J., Hafler, David A., Franklin, Robin J. M., Macosko, Evan Z., Stevens, Beth
Published in Nature neuroscience (01.03.2022)
Published in Nature neuroscience (01.03.2022)
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Journal Article
Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation
Mathur, Vidhu, Burai, Ritwik, Vest, Ryan T., Bonanno, Liana N., Lehallier, Benoit, Zardeneta, Macy E., Mistry, Karishma N., Do, Danny, Marsh, Samuel E., Abud, Edsel M., Blurton-Jones, Mathew, Li, Lingyin, Lashuel, Hilal A., Wyss-Coray, Tony
Published in Neuron (Cambridge, Mass.) (20.12.2017)
Published in Neuron (Cambridge, Mass.) (20.12.2017)
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Journal Article
Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro
Dolan, Michael-John, Therrien, Martine, Jereb, Saša, Kamath, Tushar, Gazestani, Vahid, Atkeson, Trevor, Marsh, Samuel E., Goeva, Aleksandrina, Lojek, Neal M., Murphy, Sarah, White, Cassandra M., Joung, Julia, Liu, Bingxu, Limone, Francesco, Eggan, Kevin, Hacohen, Nir, Bernstein, Bradley E., Glass, Christopher K., Leinonen, Ville, Blurton-Jones, Mathew, Zhang, Feng, Epstein, Charles B., Macosko, Evan Z., Stevens, Beth
Published in Nature immunology (01.08.2023)
Published in Nature immunology (01.08.2023)
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Journal Article
HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease
Marsh, Samuel E., Yeung, Stephen T., Torres, Maria, Lau, Lydia, Davis, Joy L., Monuki, Edwin S., Poon, Wayne W., Blurton-Jones, Mathew
Published in Stem cell reports (14.02.2017)
Published in Stem cell reports (14.02.2017)
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Journal Article
Immune Signaling in Neurodegeneration
Hammond, Timothy R., Marsh, Samuel E., Stevens, Beth
Published in Immunity (Cambridge, Mass.) (16.04.2019)
Published in Immunity (Cambridge, Mass.) (16.04.2019)
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Journal Article
Early Alzheimer’s disease pathology in human cortex involves transient cell states
Gazestani, Vahid, Kamath, Tushar, Nadaf, Naeem M., Dougalis, Antonios, Burris, S.J., Rooney, Brendan, Junkkari, Antti, Vanderburg, Charles, Pelkonen, Anssi, Gomez-Budia, Mireia, Välimäki, Nelli-Noora, Rauramaa, Tuomas, Therrien, Martine, Koivisto, Anne M., Tegtmeyer, Matthew, Herukka, Sanna-Kaisa, Abdulraouf, Abdulraouf, Marsh, Samuel E., Hiltunen, Mikko, Nehme, Ralda, Malm, Tarja, Stevens, Beth, Leinonen, Ville, Macosko, Evan Z.
Published in Cell (28.09.2023)
Published in Cell (28.09.2023)
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Journal Article
CD11a expression distinguishes infiltrating myeloid cells from plaque‐associated microglia in Alzheimer's disease
Shukla, Ankita K., McIntyre, Laura L., Marsh, Samuel E., Schneider, Christine A., Hoover, Evelyn M., Walsh, Craig M., Lodoen, Melissa B., Blurton‐Jones, Mathew, Inlay, Matthew A.
Published in Glia (01.05.2019)
Published in Glia (01.05.2019)
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Journal Article
The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease
Qureshi, Yasir H., Berman, Diego E., Marsh, Samuel E., Klein, Ronald L., Patel, Vivek M., Simoes, Sabrina, Kannan, Suvarnambiga, Petsko, Gregory A., Stevens, Beth, Small, Scott A.
Published in Cell reports (Cambridge) (18.01.2022)
Published in Cell reports (Cambridge) (18.01.2022)
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Journal Article
Human Neural Progenitor Transplantation Rescues Behavior and Reduces α‐Synuclein in a Transgenic Model of Dementia with Lewy Bodies
Goldberg, Natalie R.S., Marsh, Samuel E., Ochaba, Joseph, Shelley, Brandon C., Davtyan, Hayk, Thompson, Leslie M., Steffan, Joan S., Svendsen, Clive N., Blurton‐Jones, Mathew
Published in Stem cells translational medicine (01.06.2017)
Published in Stem cells translational medicine (01.06.2017)
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Journal Article
THE ADAPTIVE IMMUNE SYSTEM CRITICALLY REGULATES ALZHEIMER’S DISEASE PATHOGENESIS BY MODULATING MICROGLIAL FUNCTION
Marsh, Samuel E, Karimzadeh, Alborz, Abud, Edsel M, Lakatos, Anita, Yeung, Stephen T, Davtyan, Hayk, Fote, Gianna, Lau, Lydia, Weinger, Jason G, Lane, Thomas E, Poon, Wayne W, Inlay, Matthew A, Blurton-Jones, Mathew
Published in Alzheimer's & dementia (01.07.2016)
Published in Alzheimer's & dementia (01.07.2016)
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Journal Article
Multi‐modal Analysis and Modeling of Human Neurodegenerative Disease to Reveal Disease Mechanisms and Biomarkers
Marsh, Samuel E, Murphy, Sarah, Kamath, Tushar, Gazestani, Vahid, Therrien, Martine, Dolan, Michael John, Jereb, Sasa, Reyes, Miguel, Gobom, Johan, Clish, Clary, Hacohen, Nir, Zetterberg, Henrik, Leinonen, Ville, Macosko, Evan, Stevens, Beth
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Journal Article
APOE and immunity: Research highlights
Kloske, Courtney M., Barnum, Christopher J., Batista, Andre F., Bradshaw, Elizabeth M., Brickman, Adam M., Bu, Guojun, Dennison, Jessica, Gearon, Mary D., Goate, Alison M., Haass, Christian, Heneka, Michael T., Hu, William T., Huggins, Lenique K. L., Jones, Nahdia S., Koldamova, Radosveta, Lemere, Cynthia A., Liddelow, Shane A., Marcora, Edoardo, Marsh, Samuel E., Nielsen, Henrietta M., Petersen, Kellen K., Petersen, Melissa, Piña‐Escudero, Stefanie D., Qiu, Wei Qiao, Quiroz, Yakeel T., Reiman, Eric, Sexton, Claire, Tansey, Malú Gámez, TCW, Julia, Teunissen, Charlotte E., Tijms, Betty M., Kant, Rik, Wallings, Rebecca, Weninger, Stacie C., Wharton, Whitney, Wilcock, Donna M., Wishard, Tyler James, Worley, Susan L, Zetterberg, Henrik, Carrillo, Maria C.
Published in Alzheimer's & dementia (01.06.2023)
Published in Alzheimer's & dementia (01.06.2023)
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Journal Article
P1‐158: The Adaptive Immune System Critically Regulates Alzheimer’s Disease Pathogenesis by Modulating Microglial Function
Marsh, Samuel E., Karimzadeh, Alborz, Abud, Edsel M., Lakatos, Anita, Yeung, Stephen T., Davtyan, Hayk, Fote, Gianna, Lau, Lydia, Weinger, Jason G., Lane, Thomas E., Poon, Wayne W., Inlay, Matthew A., Blurton-Jones, Mathew
Published in Alzheimer's & dementia (01.07.2016)
Published in Alzheimer's & dementia (01.07.2016)
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Journal Article
Single Cell Sequencing Reveals Glial Specific Responses to Tissue Processing & Enzymatic Dissociation in Mice and Humans
Marsh, Samuel E, Kamath, Tushar, Walker, Alec J, Dissing-Olesen, Lasse, Hammond, Timothy R, Young, Adam Mh, Abdulraouf, Abdulraouf, Nadaf, Naeem, Connor Dufort, Murphy, Sarah, Kozareva, Velina, Vanderburg, Charles, Hong, Soyon, Bulstrode, Harry, Hutchinson, Peter J, Gaffney, Daniel J, Franklin, Robin Jm, Macosko, Evan Z, Stevens, Beth
Published in bioRxiv (03.12.2020)
Published in bioRxiv (03.12.2020)
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