Smac Mimetic-Induced Upregulation of CCL2/MCP-1 Triggers Migration and Invasion of Glioblastoma Cells and Influences the Tumor Microenvironment in a Paracrine Manner
Lindemann, Carina, Marschall, Viola, Weigert, Andreas, Klingebiel, Thomas, Fulda, Simone
Published in Neoplasia (New York, N.Y.) (01.06.2015)
Published in Neoplasia (New York, N.Y.) (01.06.2015)
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Expression, assembly and function of novel C‐terminal truncated variants of the mouse P2X7 receptor: re‐evaluation of P2X7 knockouts
Masin, Marianela, Young, Christopher, Lim, KoiNi, Barnes, Sara J, Xu, Xing Jian, Marschall, Viola, Brutkowski, Wojciech, Mooney, Elizabeth R, Gorecki, Dariusz C, Murrell‐Lagnado, Ruth
Published in British journal of pharmacology (01.02.2012)
Published in British journal of pharmacology (01.02.2012)
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HERA-GITRL activates T cells and promotes anti-tumor efficacy independent of FcγR-binding functionality
Richards, David M, Marschall, Viola, Billian-Frey, Katharina, Heinonen, Karl, Merz, Christian, Redondo Müller, Mauricio, Sefrin, Julian P, Schröder, Matthias, Sykora, Jaromir, Fricke, Harald, Hill, Oliver, Gieffers, Christian, Thiemann, Meinolf
Published in Journal for immunotherapy of cancer (19.07.2019)
Published in Journal for immunotherapy of cancer (19.07.2019)
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A Single-Chain-Based Hexavalent CD27 Agonist Enhances T Cell Activation and Induces Anti-Tumor Immunity
Thiemann, Meinolf, Richards, David M, Heinonen, Karl, Kluge, Michael, Marschall, Viola, Merz, Christian, Redondo Müller, Mauricio, Schnyder, Tim, Sefrin, Julian P, Sykora, Jaromir, Fricke, Harald, Gieffers, Christian, Hill, Oliver
Published in Frontiers in oncology (19.09.2018)
Published in Frontiers in oncology (19.09.2018)
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Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors
Helfinger, Valeska, von Gall, Florian Freiherr, Henke, Nina, Kunze, Michael M., Schmid, Tobias, Rezende, Flavia, Heidler, Juliana, Wittig, Ilka, Radeke, Heinfried H., Marschall, Viola, Anderson, Karen, Shah, Ajay M., Fulda, Simone, Brüne, Bernhard, Brandes, Ralf P., Schröder, Katrin
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2021)
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Abstract 1760: The hexavalent CD40 agonist HERA-CD40L augments multi-level crosstalk between T cells and antigen-presenting cells
Merz, Christian, Sykora, Jaromir, Marschall, Viola, Richards, David M., Thiemann, Meinolf, Fricke, Harald, Hill, Oliver, Gieffers, Christian
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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The Hexavalent CD40 Agonist HERA-CD40L Induces T-Cell-mediated Antitumor Immune Response Through Activation of Antigen-presenting Cells
Merz, Christian, Sykora, Jaromir, Marschall, Viola, Richards, David M, Heinonen, Karl, Redondo Müller, Mauricio, Thiemann, Meinolf, Schnyder, Tim, Fricke, Harald, Hill, Oliver, Gieffers, Christian
Published in Journal of immunotherapy (1997) (01.11.2018)
Published in Journal of immunotherapy (1997) (01.11.2018)
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Journal Article
Smac Mimetic-Induced Upregulation of CCL2/MCP-1 Triggers Migration and Invasion of Glioblastoma Cells and Influences the Tumor Microenvironment in a Paracrine Manner1
Lindemann, Carina, Marschall, Viola, Weigert, Andreas, Klingebiel, Thomas, Fulda, Simone
Published in Neoplasia (New York, N.Y.) (04.07.2015)
Published in Neoplasia (New York, N.Y.) (04.07.2015)
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Journal Article
Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1
Xu, Xing Jian, Boumechache, Miyyada, Robinson, Lucy E, Marschall, Viola, Gorecki, Dariusz C, Masin, Marianela, Murrell-Lagnado, Ruth D
Published in Journal of cell science (15.08.2012)
Published in Journal of cell science (15.08.2012)
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Abstract 1688: HERA-CD40L: A novel hexavalent CD40 agonist with superior biological activity
Merz, Christian, Sykora, Jaromir, Thiemann, Meinolf, Marschall, Viola, Heinonen, Karl H., Fricke, Harald, Gieffers, Christian, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract 630: Novel hexavalent HVEM agonist HERA-LIGHT promotes T cell activation and expansion
Sefrin, Julian P., Richards, David M., Sykora, Jaromir, Thiemann, Meinolf, Merz, Christian, Marschall, Viola, Müller, Mauricio Redondo, Heinonen, Karl, Fricke, Harald, Gieffers, Christian, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 3754: The novel hexavalent human CD137/4-1BB agonist HERA-CD137L promotes anti-cancer immunity by activating CD8 T cells while regulatory T cells are not affected
Thiemann, Meinolf, Sykora, Jaromir, Richards, David M., Merz, Christian, Marschall, Viola, Mueller, Mauricio Redondo, Sefrin, Julian P., Heinonen, Karl, Fricke, Harald, Gieffers, Christian, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 4845: HERA-CD27L, a true CD27 agonist, is a hexavalent CD27 ligand that enhances T cell activation and induces potent anti-tumor immunity
Sefrin, Julian P., Richards, David M., Billian-Frey, Katharina, Heinonen, Karl, Marschall, Viola, Merz, Christian, Müller, Mauricio Redondo, Schröder, Matthias, Sykora, Jaromir, Thiemann, Meinolf, Fricke, Harald, Gieffers, Christian, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 5015: HERA-CD40L a hexavalent CD40 agonist induces T cell mediated anti-tumor immune response and shows superior activity in direct comparison to benchmark agonistic antibodies
Gieffers, Christian, Sykora, Jaromir, Merz, Christian, Müller, Mauricio Redondo, Richards, David M., Sefrin, Julian, Billian-Frey, Katharina, Heinonen, Karl, Marschall, Viola, Schröder, Matthias, Fricke, Harald, Thiemann, Meinolf, Oliver, Hill
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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NF-κB is required for Smac mimetic-mediated sensitization of glioblastoma cells for γ-irradiation-induced apoptosis
Berger, Rebecca, Jennewein, Claudia, Marschall, Viola, Karl, Sabine, Cristofanon, Silvia, Wagner, Liane, Vellanki, Sri HariKrishna, Hehlgans, Stephanie, Rödel, Franz, Debatin, Klaus-Michael, Ludolph, Albert C, Fulda, Simone
Published in Molecular cancer therapeutics (01.10.2011)
Published in Molecular cancer therapeutics (01.10.2011)
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Abstract 4690: Hexavalent CD27 agonists show single agent anti-tumor activity and enhanced memory formation in mouse syngeneic tumor models
Gieffers, Christian, Richards, David, Sykora, Jaromir, Redondo-Müller, Mauricio, Thiemann, Meinolf, Merz, Christian, Heinonen, Karl Heinonen, Marschall, Viola, Fricke, Harald, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract 4963: Novel hexavalent GITR agonists stimulate T cells and enhance memory formation
Thiemann, Meinolf, Gieffers, Christian, Richards, David M., Merz, Christian, Heinonen, Karl, Mueller, Mauricio Redondo, Marschall, Viola, Sykora, Jaromir, Fricke, Harald, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Hydrogen peroxide formation by Nox4 limits malignant transformation
Helfinger, Valeska, Von Gall, Florian Freiherr, Henke, Nina, Kunze, Michael M, Schmid, Tobias, Heidler, Juliana, Wittig, Ilka, Radecke, Heinfried H, Marschall, Viola, Anderson, Karen, Shah, Ajay M, Fulda, Simone, Brune, Bernhard, Brandes, Ralf P, Schroder, Katrin
Published in bioRxiv (16.08.2017)
Published in bioRxiv (16.08.2017)
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