Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism
Wahlström, Annika, Sayin, Sama I., Marschall, Hanns-Ulrich, Bäckhed, Fredrik
Published in Cell metabolism (12.07.2016)
Published in Cell metabolism (12.07.2016)
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A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis
Kowdley, Kris V., Luketic, Velimir, Chapman, Roger, Hirschfield, Gideon M., Poupon, Raoul, Schramm, Christoph, Vincent, Catherine, Rust, Christian, Parés, Albert, Mason, Andrew, Marschall, Hanns‐Ulrich, Shapiro, David, Adorini, Luciano, Sciacca, Cathi, Beecher‐Jones, Tessa, Böhm, Olaf, Pencek, Richard, Jones, David
Published in Hepatology (Baltimore, Md.) (01.05.2018)
Published in Hepatology (Baltimore, Md.) (01.05.2018)
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Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD
Mardinoglu, Adil, Bjornson, Elias, Zhang, Cheng, Klevstig, Martina, Söderlund, Sanni, Ståhlman, Marcus, Adiels, Martin, Hakkarainen, Antti, Lundbom, Nina, Kilicarslan, Murat, Hallström, Björn M, Lundbom, Jesper, Vergès, Bruno, Barrett, Peter Hugh R, Watts, Gerald F, Serlie, Mireille J, Nielsen, Jens, Uhlén, Mathias, Smith, Ulf, Marschall, Hanns‐Ulrich, Taskinen, Marja‐Riitta, Boren, Jan
Published in Molecular systems biology (01.03.2017)
Published in Molecular systems biology (01.03.2017)
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6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice
Makki, Kassem, Brolin, Harald, Petersen, Natalia, Henricsson, Marcus, Christensen, Dan Ploug, Khan, Muhammad Tanweer, Wahlström, Annika, Bergh, Per-Olof, Tremaroli, Valentina, Schoonjans, Kristina, Marschall, Hanns-Ulrich, Bäckhed, Fredrik
Published in Gut (01.02.2023)
Published in Gut (01.02.2023)
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Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
Mudaliar, Sunder, Henry, Robert R, Sanyal, Arun J, Morrow, Linda, Marschall, Hanns–Ulrich, Kipnes, Mark, Adorini, Luciano, Sciacca, Cathi I, Clopton, Paul, Castelloe, Erin, Dillon, Paul, Pruzanski, Mark, Shapiro, David
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2013)
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An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans
Mardinoglu, Adil, Wu, Hao, Bjornson, Elias, Zhang, Cheng, Hakkarainen, Antti, Räsänen, Sari M., Lee, Sunjae, Mancina, Rosellina M., Bergentall, Mattias, Pietiläinen, Kirsi H., Söderlund, Sanni, Matikainen, Niina, Ståhlman, Marcus, Bergh, Per-Olof, Adiels, Martin, Piening, Brian D., Granér, Marit, Lundbom, Nina, Williams, Kevin J., Romeo, Stefano, Nielsen, Jens, Snyder, Michael, Uhlén, Mathias, Bergström, Göran, Perkins, Rosie, Marschall, Hanns-Ulrich, Bäckhed, Fredrik, Taskinen, Marja-Riitta, Borén, Jan
Published in Cell metabolism (06.03.2018)
Published in Cell metabolism (06.03.2018)
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Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist
Sayin, Sama I., Wahlström, Annika, Felin, Jenny, Jäntti, Sirkku, Marschall, Hanns-Ulrich, Bamberg, Krister, Angelin, Bo, Hyötyläinen, Tuulia, Orešič, Matej, Bäckhed, Fredrik
Published in Cell metabolism (05.02.2013)
Published in Cell metabolism (05.02.2013)
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Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses
Ovadia, Caroline, Seed, Paul T, Sklavounos, Alexandros, Geenes, Victoria, Di Ilio, Chiara, Chambers, Jenny, Kohari, Katherine, Bacq, Yannick, Bozkurt, Nuray, Brun-Furrer, Romana, Bull, Laura, Estiú, Maria C, Grymowicz, Monika, Gunaydin, Berrin, Hague, William M, Haslinger, Christian, Hu, Yayi, Kawakita, Tetsuya, Kebapcilar, Ayse G, Kebapcilar, Levent, Kondrackienė, Jūratė, Koster, Maria P H, Kowalska-Kańka, Aneta, Kupčinskas, Limas, Lee, Richard H, Locatelli, Anna, Macias, Rocio I R, Marschall, Hanns-Ulrich, Oudijk, Martijn A, Raz, Yael, Rimon, Eli, Shan, Dan, Shao, Yong, Tribe, Rachel, Tripodi, Valeria, Yayla Abide, Cigdem, Yenidede, Ilter, Thornton, Jim G, Chappell, Lucy C, Williamson, Catherine
Published in The Lancet (British edition) (02.03.2019)
Published in The Lancet (British edition) (02.03.2019)
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Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota
Wahlström, Annika, Kovatcheva-Datchary, Petia, Ståhlman, Marcus, Khan, Muhammad-Tanweer, Bäckhed, Fredrik, Marschall, Hanns-Ulrich
Published in Journal of lipid research (01.02.2017)
Published in Journal of lipid research (01.02.2017)
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Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment
Schneider, Kai Markus, Mohs, Antje, Gui, Wenfang, Galvez, Eric J. C., Candels, Lena Susanna, Hoenicke, Lisa, Muthukumarasamy, Uthayakumar, Holland, Christian H., Elfers, Carsten, Kilic, Konrad, Schneider, Carolin Victoria, Schierwagen, Robert, Strnad, Pavel, Wirtz, Theresa H., Marschall, Hanns-Ulrich, Latz, Eicke, Lelouvier, Benjamin, Saez-Rodriguez, Julio, de Vos, Willem, Strowig, Till, Trebicka, Jonel, Trautwein, Christian
Published in Nature communications (08.07.2022)
Published in Nature communications (08.07.2022)
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Moderate variations in the human diet impact the gut microbiota in humanized mice
Schoeler, Marc, Chakaroun, Rima, Brolin, Harald, Larsson, Ingrid, Perkins, Rosie, Marschall, Hanns‐Ulrich, Caesar, Robert, Bäckhed, Fredrik
Published in Acta Physiologica (01.03.2024)
Published in Acta Physiologica (01.03.2024)
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norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis
Fickert, Peter, Hirschfield, Gideon M., Denk, Gerald, Marschall, Hanns-Ulrich, Altorjay, Istvan, Färkkilä, Martti, Schramm, Christoph, Spengler, Ulrich, Chapman, Roger, Bergquist, Annika, Schrumpf, Erik, Nevens, Frederik, Trivedi, Palak, Reiter, Florian P., Tornai, Istvan, Halilbasic, Emina, Greinwald, Roland, Pröls, Markus, Manns, Michael P., Trauner, Michael
Published in Journal of hepatology (01.09.2017)
Published in Journal of hepatology (01.09.2017)
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Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2−/− mice by modulating composition, signalling and excretion of faecal bile acids
Fuchs, Claudia Daniela, Paumgartner, Gustav, Mlitz, Veronika, Kunczer, Victoria, Halilbasic, Emina, Leditznig, Nadja, Wahlström, Annika, Ståhlman, Marcus, Thüringer, Andrea, Kashofer, Karl, Stojakovic, Tatjana, Marschall, Hanns-Ulrich, Trauner, Michael
Published in Gut (01.09.2018)
Published in Gut (01.09.2018)
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Extrahepatic autoimmune diseases in primary biliary cholangitis: Prevalence and significance for clinical presentation and disease outcome
Efe, Cumali, Torgutalp, Murat, Henriksson, Ida, Alalkim, Fatema, Lytvyak, Ellina, Trivedi, Hirsh, Eren, Fatih, Fischer, Janett, Chayanupatkul, Maneerat, Coppo, Claudia, Purnak, Tugrul, Muratori, Luigi, Werner, Mårten, Muratori, Paolo, Rorsman, Fredrik, Onnerhag, Kristina, Nilsson, Emma, Heurgué‐Berlot, Alexandra, Demir, Nurhan, Semela, David, Kıyıcı, Murat, Schiano, Thomas D, Montano‐Loza, Aldo J, Berg, Thomas, Ozaslan, Ersan, Yoshida, Eric M, Bonder, Alan, Marschall, Hanns‐Ulrich, Beretta‐Piccoli, Benedetta Terziroli, Wahlin, Staffan
Published in Journal of gastroenterology and hepatology (01.04.2021)
Published in Journal of gastroenterology and hepatology (01.04.2021)
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Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis
Liao, Lijun, Schneider, Kai Markus, Galvez, Eric J C, Frissen, Mick, Marschall, Hanns-Ulrich, Su, Huan, Hatting, Maximilian, Wahlström, Annika, Haybaeck, Johannes, Puchas, Philip, Mohs, Antje, Peng, Jin, Bergheim, Ina, Nier, Anika, Hennings, Julia, Reißing, Johanna, Zimmermann, Henning W, Longerich, Thomas, Strowig, Till, Liedtke, Christian, Cubero, Francisco J, Trautwein, Christian
Published in Gut (01.08.2019)
Published in Gut (01.08.2019)
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Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity
Mueller, Michaela, Thorell, Anders, Claudel, Thierry, Jha, Pooja, Koefeler, Harald, Lackner, Carolin, Hoesel, Bastian, Fauler, Guenter, Stojakovic, Tatjana, Einarsson, Curt, Marschall, Hanns-Ulrich, Trauner, Michael
Published in Journal of hepatology (01.06.2015)
Published in Journal of hepatology (01.06.2015)
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Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis
Ovadia, Caroline, Perdones‐Montero, Alvaro, Spagou, Konstantina, Smith, Ann, Sarafian, Magali H., Gomez‐Romero, Maria, Bellafante, Elena, Clarke, Louise C.D., Sadiq, Fouzia, Nikolova, Vanya, Mitchell, Alice, Dixon, Peter H., Santa‐Pinter, Natalie, Wahlström, Annika, Abu‐Hayyeh, Shadi, Walters, Julian R.F., Marschall, Hanns‐Ulrich, Holmes, Elaine, Marchesi, Julian R., Williamson, Catherine
Published in Hepatology (Baltimore, Md.) (01.07.2019)
Published in Hepatology (Baltimore, Md.) (01.07.2019)
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