NKp46 + natural killer cells develop an activated/memory-like phenotype and contribute to innate immunity against experimental filarial infection
Pionnier, Nicolas, Furlong-Silva, Julio, Colombo, Stefano A P, Marriott, Amy E, Chunda, Valerine C, Ndzeshang, Bertrand L, Sjoberg, Hanna, Archer, John, Steven, Andrew, Wanji, Samuel, Taylor, Mark J, Turner, Joseph D
Published in Frontiers in immunology (27.09.2022)
Published in Frontiers in immunology (27.09.2022)
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A mouse infection model and long-term lymphatic endothelium co-culture system to evaluate drugs against adult Brugia malayi
Marriott, Amy E, Furlong Silva, Julio, Pionnier, Nicolas, Sjoberg, Hanna, Archer, John, Steven, Andrew, Kempf, Dale, Taylor, Mark J, Turner, Joseph D
Published in PLoS neglected tropical diseases (07.06.2022)
Published in PLoS neglected tropical diseases (07.06.2022)
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Combinations of the azaquinazoline anti- Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis
Hegde, Shrilakshmi, Marriott, Amy E, Pionnier, Nicolas, Steven, Andrew, Bulman, Christina, Gunderson, Emma, Vogel, Ian, Koschel, Marianne, Ehrens, Alexandra, Lustigman, Sara, Voronin, Denis, Tricoche, Nancy, Hoerauf, Achim, Hübner, Marc P, Sakanari, Judy, Aljayyoussi, Ghaith, Gusovsky, Fabian, Dagley, Jessica, Hong, David W, O'Neill, Paul, Ward, Steven A, Taylor, Mark J, Turner, Joseph D
Published in Frontiers in microbiology (01.02.2024)
Published in Frontiers in microbiology (01.02.2024)
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Sequential Infection with Influenza A Virus Followed by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Leads to More Severe Disease and Encephalitis in a Mouse Model of COVID-19
Clark, Jordan J, Penrice-Randal, Rebekah, Sharma, Parul, Dong, Xiaofeng, Pennington, Shaun H, Marriott, Amy E, Colombo, Stefano, Davidson, Andrew, Kavanagh Williamson, Maia, Matthews, David A, Turtle, Lance, Prince, Tessa, Hughes, Grant L, Patterson, Edward I, Shawli, Ghada, Mega, Daniele F, Subramaniam, Krishanthi, Sharp, Jo, Turner, Joseph D, Biagini, Giancarlo A, Owen, Andrew, Kipar, Anja, Hiscox, Julian A, Stewart, James P
Published in Viruses (28.05.2024)
Published in Viruses (28.05.2024)
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Validation of ultrasound bioimaging to predict worm burden and treatment efficacy in preclinical filariasis drug screening models
Marriott, Amy E., Sjoberg, Hanna, Tyrer, Hayley, Gamble, Joanne, Murphy, Emma, Archer, John, Steven, Andrew, Taylor, Mark J., Turner, Joseph D.
Published in Scientific reports (12.04.2018)
Published in Scientific reports (12.04.2018)
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In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus
Menzies, Stefanie K., Clare, Rachel H., Xie, Chunfang, Westhorpe, Adam, Hall, Steven R., Edge, Rebecca J., Alsolaiss, Jaffer, Crittenden, Edouard, Marriott, Amy E., Harrison, Robert A., Kool, Jeroen, Casewell, Nicholas R.
Published in Toxicon X (01.06.2022)
Published in Toxicon X (01.06.2022)
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African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages
Solano, Gabriela, Cunningham, Sinead, Edge, Rebecca J, Duran, Gina, Sanchez, Adriana, Villalta, Mauren, Clare, Rachel H, Wilkinson, Mark C, Marriott, Amy E, Abada, Camille, Menzies, Stefanie K, Keen, Molly, Lalloo, David G, Stienstra, Ymkje, Abouyannis, Michael, Casewell, Nicholas R, León, Guillermo, Ainsworth, Stuart
Published in BMJ global health (13.03.2024)
Published in BMJ global health (13.03.2024)
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Plug and play virus-like particles for the generation of anti-toxin antibodies
Edge, Rebecca J., Marriott, Amy E., Stars, Emma L., Patel, Rohit N., Wilkinson, Mark C., King, Lloyd D.W., Slagboom, Julien, Tan, Choo Hock, Ratanabanangkoon, Kavi, Draper, Simon J., Ainsworth, Stuart
Published in Toxicon X (01.09.2024)
Published in Toxicon X (01.09.2024)
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Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor-mediated lymphangiogenesis
Furlong-Silva, Julio, Cross, Stephen D, Marriott, Amy E, Pionnier, Nicolas, Archer, John, Steven, Andrew, Merker, Stefan Schulte, Mack, Matthias, Hong, Young-Kwon, Taylor, Mark J, Turner, Joseph D
Published in The Journal of clinical investigation (01.03.2021)
Published in The Journal of clinical investigation (01.03.2021)
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Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment
Quek, Shannon, Cook, Darren A N, Wu, Yang, Marriott, Amy E, Steven, Andrew, Johnston, Kelly L, Ford, Louise, Archer, John, Hemingway, Janet, Ward, Stephen A, Wagstaff, Simon C, Turner, Joseph D, Taylor, Mark J
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2022)
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Molecular dissection of cobra venom highlights heparinoids as an antidote for spitting cobra envenoming
Du, Tian Y, Hall, Steven R, Chung, Felicity, Kurdyukov, Sergey, Crittenden, Edouard, Patel, Karishma, Dawson, Charlotte A, Westhorpe, Adam P, Bartlett, Keirah E, Rasmussen, Sean A, Moreno, Cesar L, Denes, Christopher E, Albulescu, Laura-Oana, Marriott, Amy E, Mackay, Joel P, Wilkinson, Mark C, Gutiérrez, José María, Casewell, Nicholas R, Neely, G Gregory
Published in Science translational medicine (17.07.2024)
Published in Science translational medicine (17.07.2024)
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Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni
Partridge, Frederick A, Bataille, Carole J.R, Forman, Ruth, Marriott, Amy E, Forde-Thomas, Josephine, Häberli, Cécile, Dinsdale, Ria L, O’Sullivan, James D.B, Willis, Nicky J, Wynne, Graham M, Whiteland, Helen, Archer, John, Steven, Andrew, Keiser, Jennifer, Turner, Joseph D, Hoffmann, Karl F, Taylor, Mark J, Else, Kathryn J, Russell, Angela J, Sattelle, David B
Published in ACS infectious diseases (14.05.2021)
Published in ACS infectious diseases (14.05.2021)
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Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor–mediated lymphangiogenesis
Furlong-Silva, Julio, Cross, Stephen D, Marriott, Amy E, Pionnier, Nicolas, Archer, John, Steven, Andrew, Merker, Stefan Schulte, Mack, Matthias, Hong, Young-Kwon, Taylor, Mark J, Turner, Joseph D
Published in The Journal of clinical investigation (01.03.2021)
Published in The Journal of clinical investigation (01.03.2021)
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Handheld point-of-care devices for snakebite coagulopathy: a scoping review
Abouyannis, Michael, Marriott, Amy E, Stars, Emma, Kitchen, Dianne P, Kitchen, Steve, Woods, Tim A L, Kreuels, Benno, Amuasi, John H, Monteiro, Wuelton Marcelo, Stienstra, Ymkje, Senthilkumaran, Subramanian, Isbister, Geoffrey K, Lalloo, David G, Ainsworth, Stuart, Casewell, Nicholas R
Published in Thrombosis and haemostasis (30.08.2024)
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Published in Thrombosis and haemostasis (30.08.2024)
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Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19
Clark, Jordan J, Penrice-Randal, Rebekah, Sharma, Parul, Kipar, Anja, Dong, Xiaofeng, Pennington, Shaun, Marriott, Amy E, Colombo, Stefano, Davidson, Andrew D, Maia Kavanagh Williamson, Matthews, David A, Turtle, Lance, Prince, Tessa, Hughes, Grant, Patterson, Edward I, Shawli, Ghada, Subramaniam, Krishanthi, Sharp, Jo, Mclaughlin, Lynn, En-Min, Zhou, Turner, Joseph D, Biagini, Giancarlo, Owen, Andrew, Hiscox, Julian Alexander, Stewart, James P
Published in bioRxiv (18.01.2023)
Published in bioRxiv (18.01.2023)
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Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites - Trichuris muris, Brugia malayi, Heligmosomoides polygyrus and Schistosoma mansoni
Partridge, Frederick A, Bataille, Carole Jr, man, Ruth, Marriott, Amy E, de-Thomas, Josephine, Häberli, Cécile, Dinsdale, Ria L, James Db O’sullivan, Willis, Nicky J, Wynne, Graham M, Whiteland, Helen, Archer, John, Andrew, Steven, Keiser, Jennifer, Turner, Joseph D, Hoffmann, Karl F, Taylor, Mark J, Else, Kathryn J, Russell, Angela J, Sattelle, David B
Published in bioRxiv (07.01.2021)
Published in bioRxiv (07.01.2021)
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