Getting a Handle on Neuropharmacology by Targeting Receptor-Associated Proteins
Maher, Michael P., Matta, Jose A., Gu, Shenyan, Seierstad, Mark, Bredt, David S.
Published in Neuron (Cambridge, Mass.) (06.12.2017)
Published in Neuron (Cambridge, Mass.) (06.12.2017)
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Dual serotonin transporter/histamine H3 ligands : Optimization of the H3 pharmacophore
KEITH, John M, GOMEZ, Leslie A, MAZUR, Curt, LOVENBERG, Timothy W, CARRUTHERS, Nicholas I, LETAVIC, Michael A, LY, Kiev S, JABLONOWSKI, Jill A, SEIERSTAD, Mark, BARBIER, Ann J, WILSON, Sandy J, BOGGS, Jamin D, FRASER, Ian C
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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R3(BΔ23–27)R/I5 Chimeric Peptide, a Selective Antagonist for GPCR135 and GPCR142 over Relaxin Receptor LGR7
Kuei, Chester, Sutton, Steven, Bonaventure, Pascal, Pudiak, Cindy, Shelton, Jonathan, Zhu, Jessica, Nepomuceno, Diane, Wu, Jiejun, Chen, Jingcai, Kamme, Fredrik, Seierstad, Mark, Hack, Michael D., Bathgate, Ross A.D., Hossain, Mohammed Akhter, Wade, John D., Atack, John, Lovenberg, Timothy W., Liu, Changlu
Published in The Journal of biological chemistry (31.08.2007)
Published in The Journal of biological chemistry (31.08.2007)
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Correction: Convergent synthesis of thiodiazole dioxides from simple ketones and amines through an unusual nitrogen-migration mechanism
Punjajom, Kunlayanee, Sinclair, Paul P, Saha, Ishika, Seierstad, Mark, Ameriks, Michael K, García-Reynaga, Pablo, Lebold, Terry P, Sarpong, Richmond
Published in Chemical science (Cambridge) (17.07.2024)
Published in Chemical science (Cambridge) (17.07.2024)
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Journal Article
Convergent synthesis of thiodiazole dioxides from simple ketones and amines through an unusual nitrogen-migration mechanism
Punjajom, Kunlayanee, Sinclair, Paul P, Saha, Ishika, Seierstad, Mark, Ameriks, Michael K, García-Reynaga, Pablo, Lebold, Terry P, Sarpong, Richmond
Published in Chemical science (Cambridge) (20.12.2023)
Published in Chemical science (Cambridge) (20.12.2023)
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Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation
Babbe, Holger, Sundberg, Thomas B, Tichenor, Mark, Seierstad, Mark, Bacani, Genesis, Berstler, James, Chai, Wenying, Chang, Leon, Chung, De Michael, Coe, Kevin, Collins, Bernard, Finley, Michael, Guletsky, Alexander, Lemke, Christopher T, Mak, Puiying A, Mathur, Ashok, Mercado-Marin, Eduardo V, Metkar, Shailesh, Raymond, Donald D, Rives, Marie-Laure, Rizzolio, Michele, Shaffer, Paul L, Smith, Russell, Smith, Jacqueline, Steele, Ruth, Steffens, Helena, Suarez, Javier, Tian, Gaochao, Majewski, Nathan, Volak, Laurie P, Wei, Jianmei, Desai, Prerak T, Ong, Luvena L, Koudriakova, Tatiana, Goldberg, Steven D, Hirst, Gavin, Kaushik, Virendar K, Ort, Tatiana, Seth, Nilufer, Graham, Daniel B, Plevy, Scott, Venable, Jennifer D, Xavier, Ramnik J, Towne, Jennifer E
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2024)
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Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease
Leonard, Kristi A, Madge, Lisa A, Krawczuk, Paul J, Wang, Aihua, Kreutter, Kevin D, Bacani, Genesis M, Chai, Wenying, Smith, Russell C, Tichenor, Mark S, Harris, Michael C, Malaviya, Ravi, Seierstad, Mark, Johnson, Marguerite E, Venable, Jennifer D, Kim, Suzie, Hirst, Gavin C, Mathur, Ashok S, Rao, Tadimeti S, Edwards, James P, Rizzolio, Michele C, Koudriakova, Tatiana
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
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Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase
Tichenor, Mark S., Wiener, John J. M., Rao, Navin L., Bacani, Genesis M., Wei, Jianmei, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D., Chang, Leon, Clancy, Kathleen W., Murrey, Heather E., Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J., Wu, Jiejun, Rui, Haopeng, Sepassi, Kia, Gaudiano, Marcello, Bekkers, Mariette, Cornelissen, Ivo, Packman, Kathryn, Seierstad, Mark, Xiouras, Christos, Bembenek, Scott D., Alexander, Richard, Milligan, Cynthia, Balasubramanian, Sriram, Lebsack, Alec D., Venable, Jennifer D., Philippar, Ulrike, Edwards, James P., Hirst, Gavin
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
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Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions
McCarver, Stefan, Hanna, Luke, Samant, Andrew, Thompson, Aaron A., Seierstad, Mark, Saha, Arjun, Wu, Dongpei, Lord, Brian, Sutton, Steven W., Shah, Vishal, Milligan, Cynthia M., Wennerholm, Michelle, Shelton, Jonathan, Lebold, Terry P., Shireman, Brock T.
Published in ACS medicinal chemistry letters (11.04.2024)
Published in ACS medicinal chemistry letters (11.04.2024)
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Heteroarylureas with fused bicyclic diamine cores as inhibitors of fatty acid amide hydrolase
Keith, John M., Jones, William, Pierce, Joan M., Seierstad, Mark, Palmer, James A., Webb, Michael, Karbarz, Mark, Scott, Brian P., Wilson, Sandy J., Luo, Lin, Wennerholm, Michelle, Chang, Leon, Rizzolio, Michele, Rynberg, Raymond, Chaplan, Sandra, Guy Breitenbucher, J.
Published in Bioorganic & medicinal chemistry letters (15.10.2020)
Published in Bioorganic & medicinal chemistry letters (15.10.2020)
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Novel Reagent Space: Identifying Unorderable but Readily Synthesizable Building Blocks
Seierstad, Mark, Tichenor, Mark S, DesJarlais, Renee L, Na, Jim, Bacani, Genesis M, Chung, De Michael, Mercado-Marin, Eduardo V, Steffens, Helena C, Mirzadegan, Taraneh
Published in ACS medicinal chemistry letters (11.11.2021)
Published in ACS medicinal chemistry letters (11.11.2021)
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Preclinical Characterization of the FAAH Inhibitor JNJ-42165279
Keith, John M, Jones, William M, Tichenor, Mark, Liu, Jing, Seierstad, Mark, Palmer, James A, Webb, Michael, Karbarz, Mark, Scott, Brian P, Wilson, Sandy J, Luo, Lin, Wennerholm, Michelle L, Chang, Leon, Rizzolio, Michele, Rynberg, Raymond, Chaplan, Sandra R, Breitenbucher, J. Guy
Published in ACS medicinal chemistry letters (10.12.2015)
Published in ACS medicinal chemistry letters (10.12.2015)
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Journal Article
R3(BDelta23 27)R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization
Kuei, Chester, Sutton, Steven, Bonaventure, Pascal, Pudiak, Cindy, Shelton, Jonathan, Zhu, Jessica, Nepomuceno, Diane, Wu, Jiejun, Chen, Jingcai, Kamme, Fredrik, Seierstad, Mark, Hack, Michael D, Bathgate, Ross A D, Hossain, Mohammed Akhter, Wade, John D, Atack, John, Lovenberg, Timothy W, Liu, Changlu
Published in The Journal of biological chemistry (31.08.2007)
Published in The Journal of biological chemistry (31.08.2007)
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Discovery of Imidazo[1,2‑a]pyrazines and Pyrazolo[1,5‑c]pyrimidines as TARP γ‑8 Selective AMPAR Negative Modulators
Savall, Brad M, Wu, Dongpei, Swanson, Devin M, Seierstad, Mark, Wu, Nyantsz, Vives Martinez, Jorge, García Olmos, Beatriz, Lord, Brian, Coe, Kevin, Koudriakova, Tatiana, Lovenberg, Timothy W, Carruthers, Nicholas I, Maher, Michael P, Ameriks, Michael K
Published in ACS medicinal chemistry letters (14.03.2019)
Published in ACS medicinal chemistry letters (14.03.2019)
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Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity
Tichenor, Mark S, Wiener, John J. M, Rao, Navin L, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D, Bacani, Genesis M, Wei, Jianmei, Chang, Leon, Murrey, Heather E, Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J, Wu, JieJun, Seierstad, Mark, Bembenek, Scott D, Leonard, Kristi A, Lebsack, Alec D, Venable, Jennifer D, Edwards, James P
Published in ACS medicinal chemistry letters (13.05.2021)
Published in ACS medicinal chemistry letters (13.05.2021)
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Journal Article
Library Enhancement through the Wisdom of Crowds
Hack, Michael D, Rassokhin, Dmitrii N, Buyck, Christophe, Seierstad, Mark, Skalkin, Andrew, ten Holte, Peter, Jones, Todd K, Mirzadegan, Taraneh, Agrafiotis, Dimitris K
Published in Journal of chemical information and modeling (27.12.2011)
Published in Journal of chemical information and modeling (27.12.2011)
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