Circadian rhythm of cardiac electrophysiology, arrhythmogenesis, and the underlying mechanisms
Black, Nicholas, D’Souza, Alicia, Wang, Yanwen, Piggins, Hugh, Dobrzynski, Halina, Morris, Gwilym, Boyett, Mark R.
Published in Heart rhythm (01.02.2019)
Published in Heart rhythm (01.02.2019)
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Biophysical Characterization of the Underappreciated and Important Relationship Between Heart Rate Variability and Heart Rate
Monfredi, Oliver, Lyashkov, Alexey E, Johnsen, Anne-Berit, Inada, Shin, Schneider, Heiko, Wang, Ruoxi, Nirmalan, Mahesh, Wisloff, Ulrik, Maltsev, Victor A, Lakatta, Edward G, Zhang, Henggui, Boyett, Mark R
Published in Hypertension (Dallas, Tex. 1979) (01.12.2014)
Published in Hypertension (Dallas, Tex. 1979) (01.12.2014)
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Exercise training reduces resting heart rate via downregulation of the funny channel HCN4
D’Souza, Alicia, Bucchi, Annalisa, Johnsen, Anne Berit, Logantha, Sunil Jit R.J., Monfredi, Oliver, Yanni, Joseph, Prehar, Sukhpal, Hart, George, Cartwright, Elizabeth, Wisloff, Ulrik, Dobryznski, Halina, DiFrancesco, Dario, Morris, Gwilym M., Boyett, Mark R.
Published in Nature communications (13.05.2014)
Published in Nature communications (13.05.2014)
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Contrast enhanced micro-computed tomography resolves the 3-dimensional morphology of the cardiac conduction system in mammalian hearts
Stephenson, Robert S, Boyett, Mark R, Hart, George, Nikolaidou, Theodora, Cai, Xue, Corno, Antonio F, Alphonso, Nelson, Jeffery, Nathan, Jarvis, Jonathan C
Published in PloS one (11.04.2012)
Published in PloS one (11.04.2012)
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RNAseq shows an all-pervasive day-night rhythm in the transcriptome of the pacemaker of the heart
Wang, Yanwen, Anderson, Cali, Dobrzynski, Halina, Hart, George, D’Souza, Alicia, Boyett, Mark R.
Published in Scientific reports (11.02.2021)
Published in Scientific reports (11.02.2021)
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Journal Article
Targeting miR-423-5p Reverses Exercise Training–Induced HCN4 Channel Remodeling and Sinus Bradycardia
D’Souza, Alicia, Pearman, Charles M, Wang, Yanwen, Nakao, Shu, Logantha, Sunil Jit R.J, Cox, Charlotte, Bennett, Hayley, Zhang, Yu, Johnsen, Anne Berit, Linscheid, Nora, Poulsen, Pi Camilla, Elliott, Jonathan, Coulson, Jessica, McPhee, Jamie, Robertson, Abigail, da Costa Martins, Paula A, Kitmitto, Ashraf, Wisløff, Ulrik, Cartwright, Elizabeth J, Monfredi, Oliver, Lundby, Alicia, Dobrzynski, Halina, Oceandy, Delvac, Morris, Gwilym M, Boyett, Mark R
Published in Circulation research (13.10.2017)
Published in Circulation research (13.10.2017)
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A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate
D’Souza, Alicia, Wang, Yanwen, Anderson, Cali, Bucchi, Annalisa, Baruscotti, Mirko, Olieslagers, Servé, Mesirca, Pietro, Johnsen, Anne Berit, Mastitskaya, Svetlana, Ni, Haibo, Zhang, Yu, Black, Nicholas, Cox, Charlotte, Wegner, Sven, Bano-Otalora, Beatriz, Petit, Cheryl, Gill, Eleanor, Logantha, Sunil Jit R.J., Dobrzynski, Halina, Ashton, Nick, Hart, George, Zhang, Rai, Zhang, Henggui, Cartwright, Elizabeth J., Wisloff, Ulrik, Mangoni, Matteo E., da Costa Martins, Paula A., Piggins, Hugh D., DiFrancesco, Dario, Boyett, Mark R.
Published in Heart rhythm (01.05.2021)
Published in Heart rhythm (01.05.2021)
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Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes
Mesirca, Pietro, Nakao, Shu, Nissen, Sarah Dalgas, Forte, Gabriella, Anderson, Cali, Trussell, Tariq, Li, Jue, Cox, Charlotte, Zi, Min, Logantha, Sunil, Yaar, Sana, Cartensen, Helena, Bidaud, Isabelle, Stuart, Luke, Soattin, Luca, Morris, Gwilym M, da Costa Martins, Paula A, Cartwright, Elizabeth J, Oceandy, Delvac, Mangoni, Matteo E, Jespersen, Thomas, Buhl, Rikke, Dobrzynski, Halina, Boyett, Mark R, D'Souza, Alicia
Published in Circulation research (25.06.2021)
Published in Circulation research (25.06.2021)
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Journal Article
Point: Exercise training-induced bradycardia is caused by changes in intrinsic sinus node function
Boyett, Mark R, Wang, Yanwen, Nakao, Shu, Ariyaratnam, Jonathan, Hart, George, Monfredi, Oliver, D'Souza, Alicia
Published in Journal of applied physiology (1985) (01.09.2017)
Published in Journal of applied physiology (1985) (01.09.2017)
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Journal Article
Viewpoint: is the resting bradycardia in athletes the result of remodeling of the sinoatrial node rather than high vagal tone?
Boyett, Mark R, D'Souza, Alicia, Zhang, Henggui, Morris, Gwilym M, Dobrzynski, Halina, Monfredi, Oliver
Published in Journal of applied physiology (1985) (01.05.2013)
Published in Journal of applied physiology (1985) (01.05.2013)
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Journal Article
Supraventricular Arrhythmias in Athletes: Basic Mechanisms and New Directions
D'Souza, Alicia, Trussell, Tariq, Morris, Gwilym M, Dobrzynski, Halina, Boyett, Mark R
Published in Physiology (Bethesda, Md.) (01.09.2019)
Published in Physiology (Bethesda, Md.) (01.09.2019)
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Atrioventricular node dysfunction in pressure overload-induced heart failure-Involvement of the immune system and transcriptomic remodelling
Wilson, Claire, Zi, Min, Smith, Matthew, Hussain, Munir, D'Souza, Alicia, Dobrzynski, Halina, Boyett, Mark R
Published in Frontiers in pharmacology (04.04.2023)
Published in Frontiers in pharmacology (04.04.2023)
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Structure, function and clinical relevance of the cardiac conduction system, including the atrioventricular ring and outflow tract tissues
DOBRZYNSKI, Halina, ANDERSON, Robert H, MOORMAN, Anton F. M, NIKOLAIDOU, Thodora, SCHNEIDER, Heiko, SZUTS, Viktoria, TEMPLE, Ian P, YANNI, Joseph, BOYETT, Mark R, ATKINSON, Andrew, BORBAS, Zoltan, D'SOUZA, Alicia, FRASER, John F, INADA, Shin, LOGANTHA, Sunil J. R. J, MONFREDI, Oliver, MORRIS, Gwilym M
Published in Pharmacology & therapeutics (Oxford) (01.08.2013)
Published in Pharmacology & therapeutics (Oxford) (01.08.2013)
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The Anatomy and Physiology of the Sinoatrial Node-A Contemporary Review
MONFREDI, OLIVER, DOBRZYNSKI, HALINA, MONDAL, TAPAS, BOYETT, MARK R., MORRIS, GWILYM M.
Published in Pacing and clinical electrophysiology (01.11.2010)
Published in Pacing and clinical electrophysiology (01.11.2010)
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Journal Article
Importance of gradients in membrane properties and electrical coupling in sinoatrial node pacing
Inada, Shin, Zhang, Henggui, Tellez, James O, Shibata, Nitaro, Nakazawa, Kazuo, Kamiya, Kaichiro, Kodama, Itsuo, Mitsui, Kazuyuki, Dobrzynski, Halina, Boyett, Mark R, Honjo, Haruo
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Journal Article
Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease
Boyett, Mark R., Yanni, Joseph, Tellez, James, Bucchi, Annalisa, Mesirca, Pietro, Cai, Xue, Logantha, Sunil Jit R.J., Wilson, Claire, Anderson, Cali, Ariyaratnam, Jonathan, Stuart, Luke, Nakao, Shu, Abd Allah, Eman, Jones, Sandra, Lancaster, Matthew, Stephenson, Robert, Chandler, Natalie, Smith, Matthew, Bussey, Carol, Monfredi, Oliver, Morris, Gwilym, Billeter, Rudi, Mangoni, Matteo E., Zhang, Henggui, Hart, George, D'Souza, Alicia
Published in Progress in biophysics and molecular biology (01.11.2021)
Published in Progress in biophysics and molecular biology (01.11.2021)
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Mathematical models of the electrical action potential of Purkinje fibre cells
Stewart, Philip, Aslanidi, Oleg V., Noble, Denis, Noble, Penelope J., Boyett, Mark R., Zhang, Henggui
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (13.06.2009)
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (13.06.2009)
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