Intramuscular Administration of Paliperidone Palmitate Extended-Release Injectable Microsuspension Induces a Subclinical Inflammatory Reaction Modulating the Pharmacokinetics in Rats
Darville, Nicolas, van Heerden, Marjolein, Vynckier, An, De Meulder, Marc, Sterkens, Patrick, Annaert, Pieter, Van den Mooter, Guy
Published in Journal of pharmaceutical sciences (01.07.2014)
Published in Journal of pharmaceutical sciences (01.07.2014)
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Journal Article
High-resolution laser ablation-inductively coupled plasma-mass spectrometry imaging of cisplatin-induced nephrotoxic side effects
Van Acker, Thibaut, Van Malderen, Stijn J.M., Van Heerden, Marjolein, McDuffie, James Eric, Cuyckens, Filip, Vanhaecke, Frank
Published in Analytica chimica acta (16.11.2016)
Published in Analytica chimica acta (16.11.2016)
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Journal Article
Translational safety biomarkers of colonic barrier integrity in the rat
Erkens, Tim, Bueters, Ruud, Heerden, Marjolein, Cuyckens, Filip, Vreeken, Rob, Goeminne, Nick, Lammens, Lieve
Published in Journal of applied toxicology (01.10.2018)
Published in Journal of applied toxicology (01.10.2018)
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Journal Article
Mass Spectrometry Imaging of Drug Related Crystal-Like Structures in Formalin-Fixed Frozen and Paraffin-Embedded Rabbit Kidney Tissue Sections
Bruinen, Anne L., van Oevelen, Cateau, Eijkel, Gert B., Van Heerden, Marjolein, Cuyckens, Filip, Heeren, Ron M. A.
Published in Journal of the American Society for Mass Spectrometry (01.01.2016)
Published in Journal of the American Society for Mass Spectrometry (01.01.2016)
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Journal Article
In vitro evaluation of poloxamer in situ forming gels for bedaquiline fumarate salt and pharmacokinetics following intramuscular injection in rats
Hemelryck, Sandy Van, Dewulf, Jonatan, Niekus, Harm, van Heerden, Marjolein, Ingelse, Benno, Holm, René, Mannaert, Erik, Langguth, Peter
Published in International journal of pharmaceutics: X (01.12.2019)
Published in International journal of pharmaceutics: X (01.12.2019)
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Journal Article
Testing of acetaminophen in support of the international multilaboratory in vivo rat Pig‐a assay validation trial
van der Leede, Bas‐jan, Weiner, Sandy, Van Doninck, Terry, De Vlieger, Kathleen, Schuermans, Ann, Tekle, Fetene, Geys, Helena, van Heerden, Marjolein, De Jonghe, Sandra, Van Gompel, Jacky
Published in Environmental and molecular mutagenesis (01.06.2020)
Published in Environmental and molecular mutagenesis (01.06.2020)
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Journal Article
Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease
van der Lubbe, Joan E. M., Rosendahl Huber, Sietske K., Vijayan, Aneesh, Dekking, Liesbeth, van Huizen, Ella, Vreugdenhil, Jessica, Choi, Ying, Baert, Miranda R. M., Feddes-de Boer, Karin, Izquierdo Gil, Ana, van Heerden, Marjolein, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., de Waal, Leon, Stittelaar, Koert J., Tolboom, Jeroen T. B. M., Serroyen, Jan, Muchene, Leacky, van der Fits, Leslie, Rutten, Lucy, Langedijk, Johannes P. M., Barouch, Dan H., Schuitemaker, Hanneke, Zahn, Roland C., Wegmann, Frank
Published in npj vaccines (19.03.2021)
Published in npj vaccines (19.03.2021)
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Journal Article
The Biodistribution of the Spike Protein after Ad26.COV2.S Vaccination Is Unlikely to Play a Role in Vaccine-Induced Immune Thrombotic Thrombocytopenia
Marquez-Martinez, Sonia, Khan, Selina, Lubbe, Joan van der, Solforosi, Laura, Costes, Lea M M, Choi, Ying, Boedhoe, Satish, Verslegers, Mieke, Heerden, Marjolein van, Roosen, Wendy, Jonghe, Sandra De, Kristyanto, Hendy, Rezelj, Veronica, Hendriks, Jenny, Serroyen, Jan, Tolboom, Jeroen, Wegmann, Frank, Zahn, Roland C
Published in Vaccines (Basel) (01.05.2024)
Published in Vaccines (Basel) (01.05.2024)
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Journal Article
Booster vaccination with Ad26.COV2.S or an Omicron-adapted vaccine in pre-immune hamsters protects against Omicron BA.2
Swart, Maarten, van der Lubbe, Joan, Schmit-Tillemans, Sonja, van Huizen, Ella, Verspuij, Johan, Gil, Ana Izquierdo, Choi, Ying, Daal, Chenandly, Perkasa, Aditya, de Wilde, Adriaan, Claassen, Erwin, de Jong, Rineke, Wiese, Katrin E., Cornelissen, Lisette, van Es, Marieke, van Heerden, Marjolein, Kourkouta, Eleni, Tahiri, Issam, Mulders, Michel, Vreugdenhil, Jessica, Feddes - de Boer, Karin, Muchene, Leacky, Tolboom, Jeroen, Dekking, Liesbeth, Juraszek, Jarek, Vellinga, Jort, Custers, Jerome, Bos, Rinke, Schuitemaker, Hanneke, Wegmann, Frank, Roozendaal, Ramon, Kuipers, Harmjan, Zahn, Roland
Published in npj vaccines (16.03.2023)
Published in npj vaccines (16.03.2023)
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Journal Article
Comparison of the Local Tolerability to 5 Long-acting Drug Nanosuspensions with Different Stabilizing Excipients, Following a Single Intramuscular Administration in the Rat
Chamanza, Ronnie, Darville, Nicolas, van Heerden, Marjolein, De Jonghe, Sandra
Published in Toxicologic pathology (01.01.2018)
Published in Toxicologic pathology (01.01.2018)
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Journal Article
Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques
He, Xuan, Chandrashekar, Abishek, Zahn, Roland, Wegmann, Frank, Yu, Jingyou, Mercado, Noe B., McMahan, Katherine, Martinot, Amanda J., Piedra-Mora, Cesar, Beecy, Sidney, Ducat, Sarah, Chamanza, Ronnie, Huber, Sietske Rosendahl, van Heerden, Marjolein, van der Fits, Leslie, Borducchi, Erica N., Lifton, Michelle, Liu, Jinyan, Nampanya, Felix, Patel, Shivani, Peter, Lauren, Tostanoski, Lisa H., Pessaint, Laurent, Van Ry, Alex, Finneyfrock, Brad, Velasco, Jason, Teow, Elyse, Brown, Renita, Cook, Anthony, Andersen, Hanne, Lewis, Mark G., Schuitemaker, Hanneke, Barouch, Dan H.
Published in Cell (24.06.2021)
Published in Cell (24.06.2021)
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Journal Article
Quantitative Mass Spectrometry Imaging to Study Drug Distribution in the Intestine Following Oral Dosing
Huizing, Lennart R. S, McDuffie, James, Cuyckens, Filip, van Heerden, Marjolein, Koudriakova, Tatiana, Heeren, Ron M. A, Vreeken, Rob J
Published in Analytical chemistry (Washington) (02.02.2021)
Published in Analytical chemistry (Washington) (02.02.2021)
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Journal Article
Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules
Kourula, Stephanie, Derksen, Merel, Jardi, Ferran, Jonkers, Sophie, van Heerden, Marjolein, Verboven, Peter, Theuns, Veronique, Van Asten, Stijn, Huybrechts, Tinne, Kunze, Annett, Frazer-Mendelewska, Ewa, Lai, Ka Wai, Overmeer, René, Roos, Jamie Lee, Vries, Robert G.J., Boj, Sylvia F., Monshouwer, Mario, Pourfarzad, Farzin, Snoeys, Jan
Published in European journal of pharmaceutical sciences (01.09.2023)
Published in European journal of pharmaceutical sciences (01.09.2023)
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Journal Article
Modeling the Time Course of the Tissue Responses to Intramuscular Long-acting Paliperidone Palmitate Nano-/Microcrystals and Polystyrene Microspheres in the Rat
Darville, Nicolas, van Heerden, Marjolein, Erkens, Tim, De Jonghe, Sandra, Vynckier, An, De Meulder, Marc, Vermeulen, An, Sterkens, Patrick, Annaert, Pieter, Van den Mooter, Guy
Published in Toxicologic pathology (01.02.2016)
Published in Toxicologic pathology (01.02.2016)
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Journal Article
The effect of macrophage and angiogenesis inhibition on the drug release and absorption from an intramuscular sustained-release paliperidone palmitate suspension
Darville, Nicolas, van Heerden, Marjolein, Mariën, Dirk, De Meulder, Marc, Rossenu, Stefaan, Vermeulen, An, Vynckier, An, De Jonghe, Sandra, Sterkens, Patrick, Annaert, Pieter, Van den Mooter, Guy
Published in Journal of controlled release (28.05.2016)
Published in Journal of controlled release (28.05.2016)
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Journal Article
Cross-Species Molecular Imaging of Bile Salts and Lipids in Liver: Identification of Molecular Structural Markers in Health and Disease
Flinders, Bryn, Huizing, Lennart R. S, van Heerden, Marjolein, Cuyckens, Filip, Neumann, Ulf P, van der Laan, Luc J. W, Olde Damink, Steven W. M, Heeren, Ron M. A, Schaap, Frank G, Vreeken, Rob J
Published in Analytical chemistry (Washington) (16.10.2018)
Published in Analytical chemistry (Washington) (16.10.2018)
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Journal Article
An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines
Sistare, Frank D, Morton, Daniel, Alden, Carl, Christensen, Joel, Keller, Douglas, Jonghe, Sandra De, Storer, Richard D, Reddy, M Vijayaraj, Kraynak, Andrew, Trela, Bruce, Bienvenu, Jean-Guy, Bjurström, Sivert, Bosmans, Vanessa, Brewster, David, Colman, Karyn, Dominick, Mark, Evans, John, Hailey, James R, Kinter, Lewis, Liu, Matt, Mahrt, Charles, Marien, Dirk, Myer, James, Perry, Richard, Potenta, Daniel, Roth, Arthur, Sherratt, Philip, Singer, Thomas, Slim, Rabih, Soper, Keith, Fransson-Steen, Ronny, Stoltz, James, Turner, Oliver, Turnquist, Susan, van Heerden, Marjolein, Woicke, Jochen, DeGeorge, Joseph J
Published in Toxicologic pathology (01.06.2011)
Published in Toxicologic pathology (01.06.2011)
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Journal Article
Are condoms required to avoid damage by STDs (Sexually Transmitted Drugs)
Delille, Peter, Bailey, Graham, van Heerden, Marjolein
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2012)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2012)
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Journal Article
Multimodal non-linear optical imaging for the investigation of drug nano-/microcrystal–cell interactions
Darville, Nicolas, Saarinen, Jukka, Isomäki, Antti, Khriachtchev, Leonid, Cleeren, Dirk, Sterkens, Patrick, van Heerden, Marjolein, Annaert, Pieter, Peltonen, Leena, Santos, Hélder A., Strachan, Clare J., Van den Mooter, Guy
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2015)
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2015)
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Journal Article
Juvenile animal testing of hydroxypropyl-β-cyclodextrin in support of pediatric drug development
De Schaepdrijver, Luc, Mariën, Dirk, Rhimi, Cheyma, Voets, Marieke, van Heerden, Marjolein, Lammens, Lieve
Published in Reproductive toxicology (Elmsford, N.Y.) (15.08.2015)
Published in Reproductive toxicology (Elmsford, N.Y.) (15.08.2015)
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Journal Article