Replicability and Prediction: Lessons and Challenges from GWAS
Marigorta, Urko M., Rodríguez, Juan Antonio, Gibson, Greg, Navarro, Arcadi
Published in Trends in genetics (01.07.2018)
Published in Trends in genetics (01.07.2018)
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Journal Article
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study
Kugathasan, Subra, Dr, Denson, Lee A, MD, Walters, Thomas D, MD, Kim, Mi-Ok, PhD, Marigorta, Urko M, PhD, Schirmer, Melanie, PhD, Mondal, Kajari, PhD, Liu, Chunyan, MS, Griffiths, Anne, MD, Noe, Joshua D, MD, Crandall, Wallace V, MD, Snapper, Scott, MD, Rabizadeh, Shervin, MD, Rosh, Joel R, MD, Shapiro, Jason M, MD, Guthery, Stephen, MD, Mack, David R, MD, Kellermayer, Richard, MD, Kappelman, Michael D, MD, Steiner, Steven, MD, Moulton, Dedrick E, MD, Keljo, David, MD, Cohen, Stanley, MD, Oliva-Hemker, Maria, MD, Heyman, Melvin B, MD, Otley, Anthony R, MD, Baker, Susan S, MD, Evans, Jonathan S, MD, Kirschner, Barbara S, MD, Patel, Ashish S, MD, Ziring, David, MD, Trapnell, Bruce C, MD, Sylvester, Francisco A, MD, Stephens, Michael C, MD, Baldassano, Robert N, MD, Markowitz, James F, MD, Cho, Judy, MD, Xavier, Ramnik J, MD, Huttenhower, Curtis, PhD, Aronow, Bruce J, PhD, Gibson, Greg, PhD, Hyams, Jeffrey S, MD, Dubinsky, Marla C, MD
Published in The Lancet (British edition) (29.04.2017)
Published in The Lancet (British edition) (29.04.2017)
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Journal Article
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
Jenks, Scott A., Cashman, Kevin S., Zumaquero, Esther, Marigorta, Urko M., Patel, Aakash V., Wang, Xiaoqian, Tomar, Deepak, Woodruff, Matthew C., Simon, Zoe, Bugrovsky, Regina, Blalock, Emily L., Scharer, Christopher D., Tipton, Christopher M., Wei, Chungwen, Lim, S. Sam, Petri, Michelle, Niewold, Timothy B., Anolik, Jennifer H., Gibson, Greg, Lee, F. Eun-Hyung, Boss, Jeremy M., Lund, Frances E., Sanz, Ignacio
Published in Immunity (Cambridge, Mass.) (16.10.2018)
Published in Immunity (Cambridge, Mass.) (16.10.2018)
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Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
Claringbould, Annique, Westra, Harm-Jan, Bonder, Marc Jan, Deelen, Patrick, Kirsten, Holger, Saha, Ashis, Yazar, Seyhan, Brugge, Harm, Oelen, Roy, de Vries, Dylan H., van der Wijst, Monique G. P., Kasela, Silva, Pervjakova, Natalia, Alves, Isabel, Favé, Marie-Julie, Agbessi, Mawussé, Christiansen, Mark W., Jansen, Rick, Seppälä, Ilkka, Tong, Lin, Teumer, Alexander, Schramm, Katharina, Hemani, Gibran, Verlouw, Joost, Yaghootkar, Hanieh, Sönmez Flitman, Reyhan, Brown, Andrew, Kukushkina, Viktorija, Kalnapenkis, Anette, Rüeger, Sina, Porcu, Eleonora, Kettunen, Johannes, Lee, Bernett, Zhang, Futao, Qi, Ting, Arindrarto, Wibowo, Beutner, Frank, Dmitrieva, Julia, Elansary, Mahmoud, Fairfax, Benjamin P., Georges, Michel, Heijmans, Bastiaan T., Hewitt, Alex W., Kähönen, Mika, Kim, Yungil, Knight, Julian C., Kovacs, Peter, Krohn, Knut, Li, Shuang, Loeffler, Markus, Marigorta, Urko M., Mei, Hailang, Momozawa, Yukihide, Müller-Nurasyid, Martina, Nauck, Matthias, Nivard, Michel G., Penninx, Brenda W. J. H., Pritchard, Jonathan K., Raitakari, Olli T., Rotzschke, Olaf, Slagboom, Eline P., Stehouwer, Coen D. A., Stumvoll, Michael, Sullivan, Patrick, ’t Hoen, Peter A. C., Thiery, Joachim, Tönjes, Anke, van Dongen, Jenny, van Iterson, Maarten, Veldink, Jan H., Völker, Uwe, Warmerdam, Robert, Wijmenga, Cisca, Swertz, Morris, Andiappan, Anand, Montgomery, Grant W., Ripatti, Samuli, Perola, Markus, Kutalik, Zoltan, Dermitzakis, Emmanouil, Bergmann, Sven, van Meurs, Joyce, Prokisch, Holger, Ahsan, Habibul, Pierce, Brandon L., Lehtimäki, Terho, Psaty, Bruce M., Gharib, Sina A., Awadalla, Philip, Milani, Lili, Ouwehand, Willem H., Downes, Kate, Stegle, Oliver, Battle, Alexis, Visscher, Peter M., Yang, Jian, Powell, Joseph, Gibson, Greg, Esko, Tõnu, Franke, Lude
Published in Nature genetics (01.09.2021)
Published in Nature genetics (01.09.2021)
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Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
Xue, Angli, Wu, Yang, Zhu, Zhihong, Zhang, Futao, Kemper, Kathryn E., Zheng, Zhili, Yengo, Loic, Lloyd-Jones, Luke R., Sidorenko, Julia, Wu, Yeda, McRae, Allan F., Visscher, Peter M., Zeng, Jian, Yang, Jian
Published in Nature communications (27.07.2018)
Published in Nature communications (27.07.2018)
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Journal Article
Reconstructing the Population History of European Romani from Genome-wide Data
Mendizabal, Isabel, Lao, Oscar, Marigorta, Urko M., Wollstein, Andreas, Gusmão, Leonor, Ferak, Vladimir, Ioana, Mihai, Jordanova, Albena, Kaneva, Radka, Kouvatsi, Anastasia, Kučinskas, Vaidutis, Makukh, Halyna, Metspalu, Andres, Netea, Mihai G., de Pablo, Rosario, Pamjav, Horolma, Radojkovic, Dragica, Rolleston, Sarah J.H., Sertic, Jadranka, Macek, Milan, Comas, David, Kayser, Manfred
Published in Current biology (18.12.2012)
Published in Current biology (18.12.2012)
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A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood
Zhao, Jing, Akinsanmi, Idowu, Arafat, Dalia, Cradick, T.J., Lee, Ciaran M., Banskota, Samridhi, Marigorta, Urko M., Bao, Gang, Gibson, Greg
Published in American journal of human genetics (04.02.2016)
Published in American journal of human genetics (04.02.2016)
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Journal Article
Preclinical Inflammatory Bowel Disease: Back to the Future
Rodríguez-Lago, Iago, Marigorta, Urko M., Barreiro-de Acosta, Manuel
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2021)
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Journal Article
Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease
Marigorta, Urko M, Denson, Lee A, Hyams, Jeffrey S, Mondal, Kajari, Prince, Jarod, Walters, Thomas D, Griffiths, Anne, Noe, Joshua D, Crandall, Wallace V, Rosh, Joel R, Mack, David R, Kellermayer, Richard, Heyman, Melvin B, Baker, Susan S, Stephens, Michael C, Baldassano, Robert N, Markowitz, James F, Kim, Mi-Ok, Dubinsky, Marla C, Cho, Judy, Aronow, Bruce J, Kugathasan, Subra, Gibson, Greg
Published in Nature genetics (01.10.2017)
Published in Nature genetics (01.10.2017)
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Journal Article
Genetic factors affecting EBV copy number in lymphoblastoid cell lines derived from the 1000 Genome Project samples
Mandage, Rajendra, Telford, Marco, Rodríguez, Juan Antonio, Farré, Xavier, Layouni, Hafid, Marigorta, Urko M, Cundiff, Caitlin, Heredia-Genestar, Jose Maria, Navarro, Arcadi, Santpere, Gabriel
Published in PloS one (27.06.2017)
Published in PloS one (27.06.2017)
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Journal Article
Seroprevalence of adeno-associated virus types 1, 2, 3, 4, 5, 6, 8, and 9 in a Basque cohort of healthy donors
Navarro-Oliveros, Miguel, Vidaurrazaga, Ander, Soares Guerra, Gabriel, Castellana, Donatello, Embade, Nieves, Millet, Oscar, Marigorta, Urko M., Abrescia, Nicola G. A.
Published in Scientific reports (10.07.2024)
Published in Scientific reports (10.07.2024)
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Journal Article
Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation
Somineni, Hari K., Venkateswaran, Suresh, Kilaru, Varun, Marigorta, Urko M., Mo, Angela, Okou, David T., Kellermayer, Richard, Mondal, Kajari, Cobb, Dawayland, Walters, Thomas D., Griffiths, Anne, Noe, Joshua D., Crandall, Wallace V., Rosh, Joel R., Mack, David R., Heyman, Melvin B., Baker, Susan S., Stephens, Michael C., Baldassano, Robert N., Markowitz, James F., Dubinsky, Marla C., Cho, Judy, Hyams, Jeffrey S., Denson, Lee A., Gibson, Greg, Cutler, David J., Conneely, Karen N., Smith, Alicia K., Kugathasan, Subra
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2019)
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Results of the Seventh Scientific Workshop of ECCO: Precision Medicine in IBD—Disease Outcome and Response to Therapy
Verstockt, Bram, Noor, Nurulamin M, Marigorta, Urko M, Pavlidis, Polychronis, Deepak, Parakkal, Ungaro, Ryan C
Published in Journal of Crohn's and colitis (25.09.2021)
Published in Journal of Crohn's and colitis (25.09.2021)
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Journal Article
Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European
Olalde, Iñigo, Allentoft, Morten E., Sánchez-Quinto, Federico, Santpere, Gabriel, Chiang, Charleston W. K., DeGiorgio, Michael, Prado-Martinez, Javier, Rodríguez, Juan Antonio, Rasmussen, Simon, Quilez, Javier, Ramírez, Oscar, Marigorta, Urko M., Fernández-Callejo, Marcos, Prada, María Encina, Encinas, Julio Manuel Vidal, Nielsen, Rasmus, Netea, Mihai G., Novembre, John, Sturm, Richard A., Sabeti, Pardis, Marquès-Bonet, Tomàs, Navarro, Arcadi, Willerslev, Eske, Lalueza-Fox, Carles
Published in Nature (London) (13.03.2014)
Published in Nature (London) (13.03.2014)
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Local genetic variation of inflammatory bowel disease in Basque population and its effect in risk prediction
Garcia-Etxebarria, Koldo, Merino, Olga, Gaite-Reguero, Adrián, Rodrigues, Pedro M., Herrarte, Amaia, Etxart, Ane, Ellinghaus, David, Alonso-Galan, Horacio, Franke, Andre, Marigorta, Urko M., Bujanda, Luis, D’Amato, Mauro
Published in Scientific reports (01.03.2022)
Published in Scientific reports (01.03.2022)
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Journal Article
microRNA-based signatures obtained from endometrial fluid identify implantative endometrium
Ibañez-Perez, Jone, Díaz-Nuñez, María, Clos-García, Marc, Lainz, Lucía, Iglesias, María, Díez-Zapirain, Miren, Rabanal, Aintzane, Bárcena, Laura, González, Monika, Lozano, Juan J, Marigorta, Urko M, González, Esperanza, Royo, Félix, Aransay, Ana M, Subiran, Nerea, Matorras, Roberto, Falcón-Pérez, Juan Manuel
Published in Human reproduction (Oxford) (30.09.2022)
Published in Human reproduction (Oxford) (30.09.2022)
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