Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma
Huang, Hector H., Ferguson, Ian D., Thornton, Alexis M., Bastola, Prabhakar, Lam, Christine, Lin, Yu-Hsiu T., Choudhry, Priya, Mariano, Margarette C., Marcoulis, Makeba D., Teo, Chin Fen, Malato, Julia, Phojanakong, Paul J., Martin, Thomas G., Wolf, Jeffrey L., Wong, Sandy W., Shah, Nina, Hann, Byron, Brooks, Angela N., Wiita, Arun P.
Published in Nature communications (22.04.2020)
Published in Nature communications (22.04.2020)
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Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment
Lam, Christine, Ferguson, Ian D, Mariano, Margarette C, Lin, Yu-Hsiu T, Murnane, Megan, Liu, Hui, Smith, Geoffrey A, Wong, Sandy W, Taunton, Jack, Liu, Jun O, Mitsiades, Constantine S, Hann, Byron C, Aftab, Blake T, Wiita, Arun P
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Published in Haematologica (Roma) (01.07.2018)
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Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma
Lin, Yu-Hsiu T., Way, Gregory P., Barwick, Benjamin G., Mariano, Margarette C., Marcoulis, Makeba, Ferguson, Ian D., Driessen, Christoph, Boise, Lawrence H., Greene, Casey S., Wiita, Arun P.
Published in Blood advances (12.11.2019)
Published in Blood advances (12.11.2019)
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Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma
Ferguson, Ian D., Lin, Yu-Hsiu T., Lam, Christine, Shao, Hao, Tharp, Kevin M., Hale, Martina, Kasap, Corynn, Mariano, Margarette C., Kishishita, Audrey, Patiño Escobar, Bonell, Mandal, Kamal, Steri, Veronica, Wang, Donghui, Phojanakong, Paul, Tuomivaara, Sami T., Hann, Byron, Driessen, Christoph, Van Ness, Brian, Gestwicki, Jason E., Wiita, Arun P.
Published in Cell chemical biology (18.08.2022)
Published in Cell chemical biology (18.08.2022)
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DNA methyltransferase inhibitors upregulate CD38 protein expression and enhance daratumumab efficacy in multiple myeloma
Choudhry, Priya, Mariano, Margarette C., Geng, Huimin, Martin, Thomas G., Wolf, Jeffrey L., Wong, Sandy W., Shah, Nina, Wiita, Arun P.
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Published in Leukemia (01.03.2020)
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Modulation of the Host Environment by Human Cytomegalovirus with Viral Interleukin 10 in Peripheral Blood
Young, Vivian P., Mariano, Margarette C., Tu, Carolyn C., Allaire, Kathryn M., Avdic, Selmir, Slobedman, Barry, Spencer, Juliet V.
Published in The Journal of infectious diseases (15.03.2017)
Published in The Journal of infectious diseases (15.03.2017)
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Integrating Phosphoproteomics and Transcriptional Classifiers Reveals “Hidden Signaling” in Multiple Myeloma Including Differential KRAS and NRAS Mutant Effects
Lin, Yu-Hsiu T., Way, Gergory P., Mariano, Margarette C., Marcoulis, Makeba, Ferguson, Ian, Greene, Casey S., Wiita, Arun P
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Novel Allosteric Inhibitors of Heat Shock Protein 70 As Agents to Probe Protein Homeostasis and Overcome Proteasome Inhibitor Resistance in Multiple Myeloma
Ferguson, Ian, Lam, Christine, Mariano, Margarette C., Wang, Donghui, Phojanakong, Paul, Toumivaara, Sami, Shao, Hao, Hann, Byron C, Gestwicki, Jason, Wiita, Arun P
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Treatment of Severe COVID-19 with Convalescent Plasma in the Bronx, NYC
Yoon, Hyun Ah, Bartash, Rachel, Gendlina, Inessa, Rivera, Johanna, Nakouzi, Antonio, Bortz, 3rd, Robert H, Wirchnianski, Ariel S, Paroder, Monika, Fehn, Karen, Serrano-Rahman, Leana, Babb, Rachelle, Sarwar, Uzma N, Haslwanter, Denise, Laudermilch, Ethan, Florez, Catalina, Dieterle, M Eugenia, Jangra, Rohit K, Fels, J Maximilian, Tong, Karen, Mariano, Margarette C, Vergnolle, Olivia, Georgiev, George I, Herrera, Natalia G, Malonis, Ryan J, Quiroz, Jose A, Morano, Nicholas C, Krause, Gregory J, Sweeney, Joseph M, Cowman, Kelsie, Allen, Stephanie, Annam, Jayabhargav, Applebaum, Ariella, Barboto, Daniel, Khokhar, Ahmed, Lally, Brianna J, Lee, Audrey, Lee, Max, Malaviya, Avinash, Sample, Reise, Yang, Xiuyi A, Li, Yang, Ruiz, Rafael, Thota, Raja, Barnhill, Jason, Goldstein, Doctor Y, Uehlinger, Joan, Garforth, Scott J, Almo, Steven C, Lai, Jonathan R, Gil, Morayma Reyes, Fox, Amy S, Chandran, Kartik, Wang, Tao, Daily, Johanna P, Pirofski, Liise-Anne
Published in medRxiv : the preprint server for health sciences (04.12.2020)
Published in medRxiv : the preprint server for health sciences (04.12.2020)
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Journal Article
Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma
Ferguson, Ian D, Lin, Yu-Hsiu T, Lam, Christine, Shao, Hao, Hale, Martina, Tharp, Kevin M, Mariano, Margarette C, Steri, Veronica, Wang, Donghui, Phojanokong, Paul, Tuomivaara, Sami T, Hann, Byron, Driessen, Christoph, Brian Van Ness, Gestwicki, Jason E, Wiita, Arun P
Published in bioRxiv (23.04.2020)
Published in bioRxiv (23.04.2020)
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Integrated Phosphoproteomics and Transcriptional Classifiers Reveal Hidden RAS Signaling Dynamics in Multiple Myeloma
Yu-Hsiu Tony Lin, Way, Gregory P, Barwick, Benjamin G, Mariano, Margarette C, Marcoulis, Makeba, Ferguson, Ian D, Driessen, Christoph, Boise, Lawrence H, Greene, Casey S, Wiita, Arun P
Published in bioRxiv (28.02.2019)
Published in bioRxiv (28.02.2019)
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Paper
Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma
Hector Han-Li Huang, Ferguson, Ian D, Thornton, Alexis M, Lam, Christine Y T, Yu-Hsiu Tony Lin, Bastola, Prabhakar, Choudhry, Priya, Mariano, Margarette C, Marcoulis, Makeba D, Malato, Julia, Phojanakong, Paul, Martin, Thomas G, Wolf, Jeffrey L, Wong, Sandy W, Shah, Nina, Hann, Byron C, Brooks, Angela N, Wiita, Arun P
Published in bioRxiv (03.02.2019)
Published in bioRxiv (03.02.2019)
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