Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma
Motzer, Robert J, Penkov, Konstantin, Haanen, John, Rini, Brian, Albiges, Laurence, Campbell, Matthew T, Venugopal, Balaji, Kollmannsberger, Christian, Negrier, Sylvie, Uemura, Motohide, Lee, Jae L, Vasiliev, Aleksandr, Miller, Wilson H, Gurney, Howard, Schmidinger, Manuela, Larkin, James, Atkins, Michael B, Bedke, Jens, Alekseev, Boris, Wang, Jing, Mariani, Mariangela, Robbins, Paul B, Chudnovsky, Aleksander, Fowst, Camilla, Hariharan, Subramanian, Huang, Bo, di Pietro, Alessandra, Choueiri, Toni K
Published in The New England journal of medicine (21.03.2019)
Published in The New England journal of medicine (21.03.2019)
Get full text
Journal Article
A phase I study of danusertib (PHA-739358) in adult patients with accelerated or blastic phase chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia resistant or intolerant to imatinib and/or other second generation c-ABL therapy
Borthakur, Gautam, Dombret, Herve, Schafhausen, Philippe, Brummendorf, Tim Henrik, Boissel, Nicolas, Jabbour, Elias, Mariani, Mariangela, Capolongo, Laura, Carpinelli, Patrizia, Davite, Cristina, Kantarjian, Hagop, Cortes, Jorge E
Published in Haematologica (Roma) (01.07.2015)
Published in Haematologica (Roma) (01.07.2015)
Get full text
Journal Article
A Phase I Dose-Escalation Study of Danusertib (PHA-739358) Administered as a 24-Hour Infusion with and without Granulocyte Colony-Stimulating Factor in a 14-Day Cycle in Patients with Advanced Solid Tumors
Cohen, Roger B, Jones, Suzanne F, Aggarwal, Charu, von Mehren, Margaret, Cheng, Jonathan, Spigel, David R, Greco, F Anthony, Mariani, Mariangela, Rocchetti, Maurizio, Ceruti, Roberta, Comis, Silvia, Laffranchi, Bernard, Moll, Jurgen, Burris, Howard A
Published in Clinical cancer research (01.11.2009)
Published in Clinical cancer research (01.11.2009)
Get full text
Journal Article
Phase I Pharmacokinetic and Pharmacodynamic Study of the Aurora Kinase Inhibitor Danusertib in Patients With Advanced or Metastatic Solid Tumors
STEEGHS, Neeltje, ESKENS, Ferry A. L. M, LAFFRANCHI, Bernard, DE JONGE, Maja J. A, GELDERBLOM, Hans, VERWEIJ, Jaap, NORTIER, Johan W. R, OUWERKERK, Jan, VAN NOORT, Conny, MARIANI, Mariangela, SPINELLI, Riccardo, CARPINELLI, Patrizia
Published in Journal of clinical oncology (20.10.2009)
Published in Journal of clinical oncology (20.10.2009)
Get full text
Journal Article
Association between neutrophil-to-eosinophil ratio and efficacy outcomes with avelumab plus axitinib or sunitinib in patients with advanced renal cell carcinoma: post hoc analyses from the JAVELIN Renal 101 trial
Tucker, Matthew, Chen, Yu-Wei, Voss, Martin H, McGregor, Bradley A, Bilen, Mehmet A, Grimm, Marc-Oliver, Nathan, Paul, Kollmannsberger, Christian, Tomita, Yoshihiko, Huang, Bo, Amezquita, Robert, Mariani, Mariangela, di Pietro, Alessandra, Rini, Brian
Published in BMJ Oncology (01.07.2024)
Published in BMJ Oncology (01.07.2024)
Get full text
Journal Article
Avelumab plus axitinib vs sunitinib as first-line treatment of advanced renal cell carcinoma: Phase 3 study (JAVELIN Renal 101)
Choueiri, Toni K., Rini, Brian I., Larkin, James M. G., Bjarnason, Georg A., Gravis, Gwenaelle, Gurney, Howard, Lee, Jae-Lyun, Keizman, Daniel, Haanen, John B. A. G., Tomita, Yoshihiko, Uemura, Hirotsugu, Albiges, Laurence, Schmidinger, Manuela, Atkins, Michael B., Mariani, Mariangela, Shnaidman, Michael, di Pietro, Alessandra, Motzer, Robert J.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
Get full text
Journal Article
Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib
Steeghs, Neeltje, Mathijssen, Ron H. J., Wessels, Judith A. M., de Graan, Anne-Joy, van der Straaten, Tahar, Mariani, Mariangela, Laffranchi, Bernard, Comis, Silvia, de Jonge, Maja J. A., Gelderblom, Hans, Guchelaar, Henk-Jan
Published in Investigational new drugs (01.10.2011)
Published in Investigational new drugs (01.10.2011)
Get full text
Journal Article
Prospective Cardiovascular Surveillance of Immune Checkpoint Inhibitor-Based Combination Therapy in Patients With Advanced Renal Cell Cancer: Data From the Phase III JAVELIN Renal 101 Trial
Rini, Brian I, Moslehi, Javid J, Bonaca, Marc, Schmidinger, Manuela, Albiges, Laurence, Choueiri, Toni K, Motzer, Robert J, Atkins, Michael B, Haanen, John, Mariani, Mariangela, Wang, Jing, Hariharan, Subramanian, Larkin, James
Published in Journal of clinical oncology (10.06.2022)
Published in Journal of clinical oncology (10.06.2022)
Get full text
Journal Article
Impact of Prior Cytoreductive Nephrectomy on Efficacy in Patients with Synchronous Metastatic Renal Cell Carcinoma Treated with Avelumab plus Axitinib or Sunitinib: Post Hoc Analysis from the JAVELIN Renal 101 Phase 3 Trial
Grimm, Marc-Oliver, Oya, Mototsugu, Choueiri, Toni K, Motzer, Robert J, Schmidinger, Manuela, Quinn, David I, Gravis-Mescam, Gwenaelle, Verzoni, Elena, Van den Eertwegh, Alfonsus J M, di Pietro, Alessandra, Mariani, Mariangela, Wang, Jing, Thomaidou, Despina, Albiges, Laurence
Published in European urology (01.01.2024)
Published in European urology (01.01.2024)
Get full text
Journal Article
Efficacy and safety of avelumab plus axitinib (A + Ax) versus sunitinib (S) in elderly patients with advanced renal cell carcinoma (aRCC): Extended follow-up results from JAVELIN Renal 101
Tomita, Yoshihiko, Motzer, Robert J., Choueiri, Toni K., Rini, Brian I., Miyake, Hideaki, Uemura, Hirotsugu, Albiges, Laurence, Fujii, Yosuke, Umeyama, Yoshiko, Wang, Jing, Mariani, Mariangela, Schmidinger, Manuela
Published in Journal of clinical oncology (20.02.2021)
Published in Journal of clinical oncology (20.02.2021)
Get full text
Journal Article
Association of C-reactive protein (CRP) with efficacy of avelumab + axitinib (A + Ax) in advanced renal cell carcinoma (aRCC): Long-term follow-up results from JAVELIN Renal 101
Tomita, Yoshihiko, Larkin, James, Venugopal, Balaji, Haanen, John B. A. G., Kanayama, Hiro-Omi, Eto, Masatoshi, Grimm, Marc-Oliver, Fujii, Yosuke, Umeyama, Yoshiko, Mariani, Mariangela, Di Pietro, Alessandra, Choueiri, Toni K.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Efficacy of avelumab + axitinib (A + Ax) versus sunitinib (S) by IMDC risk group in advanced renal cell carcinoma (aRCC): Extended follow-up results from JAVELIN Renal 101
Haanen, John B. A. G., Larkin, James, Choueiri, Toni K., Albiges, Laurence, Rini, Brian I., Atkins, Michael B., Schmidinger, Manuela, Penkov, Konstantin, Thomaidou, Despina, Wang, Jing, Mariani, Mariangela, Di Pietro, Alessandra, Motzer, Robert J.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Association between neutrophil-to-eosinophil ratio (NER) and efficacy outcomes in the JAVELIN Renal 101 study
Tucker, Matthew D., Voss, Martin H, Choueiri, Toni K., Bilen, Mehmet Asim, Grimm, Marc-Oliver, Nathan, Paul D., Kollmannsberger, Christian K., Tomita, Yoshihiko, Huang, Bo, Thomaidou, Despina, Mariani, Mariangela, Di Pietro, Alessandra, Rini, Brian I.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Outcomes of patients who progressed while receiving avelumab + axitinib (A + Ax) and received subsequent treatment (Tx) in JAVELIN Renal 101
Albiges, Laurence, Voss, Martin H, Rini, Brian I., Gravis, Gwenaelle, Grimm, Marc-Oliver, Nathan, Paul D., Bjarnason, Georg A., Tomita, Yoshihiko, Penkov, Konstantin, McGregor, Bradley, Huang, Bo, Thomaidou, Despina, Mariani, Mariangela, Di Pietro, Alessandra, Choueiri, Toni K.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Randomized phase II study of danusertib in patients with metastatic castration‐resistant prostate cancer after docetaxel failure
Meulenbeld, Hielke J., Bleuse, Jean P., Vinci, Elio M., Raymond, Eric, Vitali, Giordano, Santoro, Armando, Dogliotti, Luigi, Berardi, Rossana, Cappuzzo, Federico, Tagawa, Scott T., Sternberg, Cora N., Jannuzzo, Maria G., Mariani, Mariangela, Petroccione, Anna, Wit, Ronald
Published in BJU international (01.01.2013)
Published in BJU international (01.01.2013)
Get full text
Journal Article
Evaluation of brain metastasis in JAVELIN Renal 101: Efficacy of avelumab + axitinib (A+Ax) versus sunitinib (S)
Jonasch, Eric, Hasanov, Elshad, Motzer, Robert J., Hariharan, Subramanian, Choueiri, Toni K., Huang, Bo, Haanen, John B. A. G., Albiges, Laurence, Venugopal, Balaji, Schmidinger, Manuela, Larkin, James M. G., Grimm, Marc-Oliver, Negrier, Sylvie, Wang, Jing, Mariani, Mariangela, Chudnovsky, Aleksander, di Pietro, Alessandra, Rini, Brian I.
Published in Journal of clinical oncology (20.02.2020)
Published in Journal of clinical oncology (20.02.2020)
Get full text
Journal Article
Phase II trial of nemorubicin hydrochloride (N) in combination with cisplatin (cDDP) administered by intra-hepatic artery (IHA) in patients (pts) with hepatocellular carcinoma (HCC): Final results
Izzo, Francesco, Vogl, Thomas J., Gadaleta-Caldarola, Gennaro, Middleton, Mark R., Valle, Juan W., Hammerstingl, Renate, Gadaleta, Cosmo D., Martignoni, Marcella, Petroccione, Anna, Mariani, Mariangela, Davite, Cristina, Fiore, Francesco
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
Get full text
Journal Article
Phase II study of danusertib (D) in advanced/metastatic non-small cell lung cancers (NSCLC)
Gauler, Thomas Christoph, Besse, Benjamin, Novello, Silvia, Smit, Egbert F., Plummer, Elizabeth R., Delord, Jean-Pierre, Nicodemo, Maurizio, Santoro, Armando, Barone, Carlo, Marchetti, Paolo, Conte, Pier Franco, De Jonge, Maja J., Awada, Ahmad, Mariani, Mariangela, Jannuzzo, Maria Gabriella, Petroccione, Anna, Ceruti, Roberta, Davite, Cristina, Eberhardt, Wilfried Ernst Erich
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
Get full text
Journal Article
A Phase I Dose-Escalation Study of Danusertib (PHA-739358) Administered as a 24-hour Infusion With and Without G-CSF in a 14-day Cycle in Patients with Advanced Solid Tumors
Cohen, Roger B., Jones, Suzanne F., Aggarwal, Charu, von Mehren, Margaret, Cheng, Jonathan, Spigel, David R., Greco, F. Anthony, Mariani, Mariangela, Rocchetti, Maurizio, Ceruti, Roberta, Comis, Silvia, Laffranchi, Bernard, Moll, Jurgen, Burris, Howard A.
Published in Clinical cancer research (13.10.2009)
Published in Clinical cancer research (13.10.2009)
Get full text
Journal Article