AG337, a novel lipophilic thymidylate synthase inhibitor: in vitro and in vivo preclinical studies
Webber, S, Bartlett, C A, Boritzki, T J, Hillard, J A, Howland, E F, Johnston, A L, Kosa, M, Margosiak, S A, Morse, C A, Shetty, B V
Published in Cancer chemotherapy and pharmacology (1996)
Published in Cancer chemotherapy and pharmacology (1996)
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Protein Structure-Based Design, Synthesis, and Biological Evaluation of 5-Thia-2,6-diamino-4(3H)-oxopyrimidines: Potent Inhibitors of Glycinamide Ribonucleotide Transformylase with Potent Cell Growth Inhibition
Varney, Michael D, Palmer, Cindy L, Romines, William H, Boritzki, Theodore, Margosiak, Stephen A, Almassy, Robert, Janson, Cheryl A, Bartlett, Charlotte, Howland, Eleanor J, Ferre, Rosanne
Published in Journal of medicinal chemistry (01.08.1997)
Published in Journal of medicinal chemistry (01.08.1997)
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Identification of the large subunit of ribulose 1,5-bisphosphate carboxylase/oxygenase as a substrate for transglutaminase in Medicago sativa L. (alfalfa)
MARGOSIAK, S. A, DHARMA, A, BRUCE-CARVER, M. R, GONZALES, A. P, LOUIE, D, KUEHN, G. D
Published in Plant physiology (Bethesda) (1990)
Published in Plant physiology (Bethesda) (1990)
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Structure of the Human Cytomegalovirus Protease Catalytic Domain Reveals a Novel Serine Protease Fold and Catalytic Triad
Chen, Ping, Tsuge, Hideaki, Almassy, Robert J., Gribskov, Cindy L., Katoh, Susumu, Vanderpool, Darin L., Margosiak, Stephen A., Pinko, Christopher, Matthews, David A., Kan, Chen-Chen
Published in Cell (06.09.1996)
Published in Cell (06.09.1996)
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Single-chain recombinant human cytomegalovirus protease. Activity against its natural protein substrate and fluorogenic peptide substrates
Pinko, C, Margosiak, S A, Vanderpool, D, Gutowski, J C, Condon, B, Kan, C C
Published in The Journal of biological chemistry (06.10.1995)
Published in The Journal of biological chemistry (06.10.1995)
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AG2034: a novel inhibitor of glycinamide ribonucleotide formyltransferase
Boritzki, T J, Barlett, C A, Zhang, C, Howland, E F
Published in Investigational new drugs (01.01.1996)
Published in Investigational new drugs (01.01.1996)
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Single-chain recombinant human cytomegalovirus protease. Activity against its natural protein substrate and fluorogenic peptide substrates
Pinko, C, Margosiak, SA, Vanderpool, D, Gutowski, J C, Condon, B, Kan, Chen-Chen
Published in The Journal of biological chemistry (01.01.1995)
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Published in The Journal of biological chemistry (01.01.1995)
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SYNTHESIS AND BIOLOGICAL EVALUATION OF N-[4-(2-TRANS-[([2,6-DIAMINO-4(3H)-OXOPYRIMIDIN-5-YL]METHYL)THIO]CYCLOBUTYL)BENZOYL]-L-GLUTAMIC ACID A NOVEL 5-THIAPYRIMIDINONE INHIBITOR OF DIHYDROFOLATE-REDUCTASE
VARNEY, MD, ROMINES, WH, BORITZKI, T, MARGOSIAK, SA, BARTLETT, C, HOWLAND, EJ
Published in Journal of heterocyclic chemistry (01.09.1995)
Published in Journal of heterocyclic chemistry (01.09.1995)
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PEPTIDE MUTANT OF HUMAN ERAB/HADH2, ITS X-RAY CRYSTAL STRUCTURE, AND MATERIALS AND METHOD FOR IDENTIFICATION OF INHIBITORS THEREOF
JERRY J. MENG, MELWYN A. ABREO, PAUL ABRAHAM REJTO, LAURA A. PELLETIER, DARIN LOUIS VANDERPOOL, RICHARD EDWARD SHOWALTER, JAMES ARTHUR THOMSON, ANNA TEMPCZYK-RUSSEL, JESUS ERNESTO VILLAFRANCA, ROBERT M. AUST, CHARLES R. KISSINGER, CHARLES S. AGREE, STEPHEN MARGOSIAK
Year of Publication 03.01.2003
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Year of Publication 03.01.2003
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CATALYTIC DOMAIN OF THE HUMAN EFFECTOR CELL CYCLE CHECKPOINT PROTEIN KINASE, CHK1, MATERIALS AND METHOD FOR IDENTIFICATION OF INHIBITORS THEREOF
KAN CHENN, NGUYEN BINH, SARUP JAY CHAND, REGISTER JAMES, CHEN PING, LUNDGREN KAREN, LUO CHUN, ANDERSON MARK BRIAN, GAUR SMITA, MARGOSIAK STEPHEN, TEMPCZYK-RUSSEL ANNA, DENG YA-LI, O'CONNOR PATRICK
Year of Publication 25.06.2001
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Year of Publication 25.06.2001
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