Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer's disease
Whelan, Christopher D, Mattsson, Niklas, Nagle, Michael W, Vijayaraghavan, Swetha, Hyde, Craig, Janelidze, Shorena, Stomrud, Erik, Lee, Julie, Fitz, Lori, Samad, Tarek A, Ramaswamy, Gayathri, Margolin, Richard A, Malarstig, Anders, Hansson, Oskar
Published in Acta neuropathologica communications (06.11.2019)
Published in Acta neuropathologica communications (06.11.2019)
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The roles of inflammation and immune mechanisms in Alzheimer's disease
Van Eldik, Linda J, Carrillo, Maria C, Cole, Patricia E, Feuerbach, Dominik, Greenberg, Barry D, Hendrix, James A, Kennedy, Matthew, Kozauer, Nick, Margolin, Richard A, Molinuevo, José L, Mueller, Reinhold, Ransohoff, Richard M, Wilcock, Donna M, Bain, Lisa, Bales, Kelly
Published in Alzheimer's & dementia : translational research & clinical interventions (01.06.2016)
Published in Alzheimer's & dementia : translational research & clinical interventions (01.06.2016)
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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PF-06751979, a Potent and Selective Oral BACE1 Inhibitor: Results from Phase I Studies in Healthy Adults and Healthy Older Subjects
Qiu, Ruolun, Ahn, Jae Eun, Alexander, Robert, Brodney, Michael A., He, Ping, Leurent, Claire, Mancuso, Jessica, Margolin, Richard A., Tankisheva, Ekaterina, Chen, Danny
Published in Journal of Alzheimer's disease (01.01.2019)
Published in Journal of Alzheimer's disease (01.01.2019)
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A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Safety, Pharmacokinetics, and Biomarker Results of Subcutaneous Bapineuzumab in Patients with mild to moderate Alzheimer's disease
Brody, Mark, Liu, Enchi, Di, Jianing, Lu, Ming, Margolin, Richard A, Werth, John L, Booth, Kevin, Shadman, Anna, Brashear, H Robert, Novak, Gerald
Published in Journal of Alzheimer's disease (18.10.2016)
Published in Journal of Alzheimer's disease (18.10.2016)
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PROGRESS IN DEVELOPING A LIGHT‐STABLE 4R TAU PET IMAGING AGENT: APN‐1701 FIH
Tempest, Paul, Lin, Yih‐Shyan, Tai, Chin‐Yin, Ono, Maiko, Russell, David S, Sandiego, Christine M, Gunn, Roger N, Carroll, Vincent, Margolin, Richard A, Kao, Tzu‐Huei, Higuchi, Makoto, Jang, Ming‐Kuei
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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ADVANCING THERAPEUTICS FOR NEUROINFLAMMATION IN ALZHEIMER'S DISEASE: CLINICAL DEVELOPMENT CONSIDERATIONS
Margolin, Richard A, Schneider, Lon S, Cutter, Gary R, Breitner, John C.S, Doody, Rachelle S, Landreth, Gary, Chain, Daniel
Published in Alzheimer's & dementia (01.07.2016)
Published in Alzheimer's & dementia (01.07.2016)
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POOLED AMYLOID PET BASELINE DATA FROM THE BAPINEUZUMAB IV PHASE III TRIALS
Hill, Derek L, Novak, Gerald P, Wolz, Robin, Liu, Enchi, Lucas, Prisca, Fox, Nick C, Scheltens, Philip, Gray, Katherine R, Booth, Kevin, Einstein, Steven G, Schmidt, Mark E, Li, David Jianjun, Styren, Scot D, Margolin, Richard A, McCarthy, Timothy J, Brashear, Robert Robert
Published in Alzheimer's & dementia (01.07.2016)
Published in Alzheimer's & dementia (01.07.2016)
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TIMING AND TRAJECTORY OF ESTABLISHED MECHANISMS: AMYLOID β AND TAU DEPOSITION, AND NEURODEGENERATION
Margolin, Richard A., Jack, Clifford R., Landau, Susan M.
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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IN‐VIVO EVALUATION OF APN‐1808, A TAU SMALL MOLECULE THERAPEUTIC
Tempest, Paul, Lin, Yih‐Shyan, Lai, Yen‐Ting, Tai, Chin‐Yin, Ma, Haou‐Tzong, Huang, Sheng‐Chieh, Margolin, Richard A, Wu, Chia‐Lin, Jang, Ming‐Kuei
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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APNmAb005, an anti‐tau antibody targeting synaptic tau oligomers, in Phase 1 for treatment of Alzheimer’s Disease and primary tauopathies
Tai, Chin‐Yin, Ma, Haou‐Tzong, Li, Chung‐Lin, Fang Wu, Meng‐, Wang, Silas, Wu, Chia‐Lin, Lai, Yen‐Ting, Serrano, Geidy E, Beach, Thomas G, Margolin, Richard A, Zhang, Lili, Jang, Ming‐Kuei, Navia, Bradford
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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PROGRESS TOWARDS AN A‐SYNUCLEIN PET TRACER
Tempest, Paul, Tai, Chin‐Yin, Ono, Maiko, Skaddan, Marc B, Wilcox, Kyle C, Reed, Aimee, Vaidyanathan, Srirajan, Christoffersen, Claus T, Kallunki, Pekka, Bang‐Andersen, Benny, Margolin, Richard A, Kao, Tzu‐Huei, Higuchi, Makoto, Jang, Ming‐Kuei
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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PROGRESS IN DEVELOPING A LIGHT‐STABLE 4R TAU PET IMAGING AGENT: APN‐1701 FIH
Tempest, Paul, Lin, Yih‐Shyan, Tai, Chin‐Yin, Ono, Maiko, Russell, David S, Sandiego, Christine M, Carroll, Vincent, Gunn, Roger N, Margolin, Richard A, Higuchi, Makoto, Jang, Ming‐Kuei
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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P3‐012: Advancing Therapeutics for Neuroinflammation in Alzheimer's Disease: Clinical Development Considerations
Margolin, Richard A., Schneider, Lon S., Cutter, Gary R., Breitner, John C.S., Doody, Rachelle S., Landreth, Gary, Chain, Daniel
Published in Alzheimer's & dementia (01.07.2016)
Published in Alzheimer's & dementia (01.07.2016)
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