Non-clinical immunological comparison of a Next-Generation 24-valent pneumococcal conjugate vaccine (VAX-24) using site-specific carrier protein conjugation to the current standard of care (PCV13 and PPV23)
Fairman, Jeff, Agarwal, Paresh, Barbanel, Sandrine, Behrens, Christopher, Berges, Aym, Burky, John, Davey, Peter, Fernsten, Phil, Grainger, Chris, Guo, Sherry, Iki, Sam, Iverson, Mark, Kane, Martin, Kapoor, Neeraj, Marcq, Olivier, Migone, Thi-Sau, Sauer, Paul, Wassil, James
Published in Vaccine (27.05.2021)
Published in Vaccine (27.05.2021)
Get full text
Journal Article
Characterization and Higher-Order Structure Assessment of an Interchain Cysteine-Based ADC: Impact of Drug Loading and Distribution on the Mechanism of Aggregation
Guo, Jianxin, Kumar, Sandeep, Chipley, Mark, Marcq, Olivier, Gupta, Devansh, Jin, Zhaowei, Tomar, Dheeraj S, Swabowski, Cecily, Smith, Jacquelynn, Starkey, Jason A, Singh, Satish K
Published in Bioconjugate chemistry (16.03.2016)
Published in Bioconjugate chemistry (16.03.2016)
Get full text
Journal Article
Glycoconjugates: What It Would Take To Master These Well-Known yet Little-Understood Immunogens for Vaccine Development
Avci, Fikri, Berti, Francesco, Dull, Peter, Hennessey, John, Pavliak, Viliam, Prasad, A Krishna, Vann, Willie, Wacker, Michael, Marcq, Olivier
Published in mSphere (25.09.2019)
Published in mSphere (25.09.2019)
Get full text
Journal Article
Addition of Lauryldimethylamine N‑Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes
Bautista, Leslie, Pill-Pepe, Lucy, Kapoor, Neeraj, Snyder, Scott, Chu, Ellen, Agarwal, Paresh, Sardar, Mohammed, Arulkumar, Shylaja, Berges, Aym, Iverson, Mark, Behrens, Christopher, Marcq, Olivier, Fairman, Jeff
Published in ACS omega (04.10.2022)
Published in ACS omega (04.10.2022)
Get full text
Journal Article
Abstract 2622: TUB-040, a novel Napi2b-targeting ADC built with ethynylphosphonamidate conjugation chemistry, demonstrates high and long-lasting anti-tumor efficacy via Topoisomerase-I inhibition and excellent tolerability predictive of a wide therapeutic window in humans
Schmitt, Saskia, Mai, Isabelle, Machui, Paul, Herterich, Sarah, Hauswald, Danila, Ochtrop, Philipp, Cyprys, Philipp, Kozlowska, Izabela, Kitowski, Annabel, Gerlach, Marcus, Marcq, Olivier, Trail, Pamela A., Schumacher, Dominik, Kasper, Marc-André, Fingerle-Rowson, Günter, Hock, Björn, Helma-Smets, Jonas, Vogl, Annette M.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Abstract 2623: Enabling 5T4 for targeted cancer therapy: TUB-030, a novel ADC built with ethynylphosphonamidate conjugation chemistry, shows long-lasting anti-tumor activity via Topoisomerase-I inhibition with an optimized therapeutic index
Schmitt, Saskia, Mai, Isabelle, Machui, Paul, Herterich, Sarah, Hauswald, Danila, Ochtrop, Philipp, Cyprys, Philipp, Kozlowska, Izabela, Kitowski, Annabel, Gerlach, Marcus, Marcq, Olivier, Trail, Pamela A., Schumacher, Dominik, Kasper, Marc-André, Fingerle-Rowson, Günter, Hock, Björn, Helma-Smets, Jonas, Vogl, Annette M.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
1047. Development of a Next Generation 30+ Valent Pneumococcal Conjugate Vaccine (VAX-XP) Using Site-Specific Carrier Protein Conjugation
Behrens, Chris, Fairman, Jeff, Agarwal, Paresh, Arulkumar, Shylaja, Barbanel, Sandrine, Bautista, Leslie, Berges, Aym, Burky, John, Davey, Peter, Grainger, Chris, Guo, Sherry, Iki, Sam, Iverson, Mark, Kapoor, Neeraj, Marcq, Olivier, Migone, Thi-Sau, Pill, Lucy, Sardar, Mohammed, Sauer, Paul, Wassil, James
Published in Open forum infectious diseases (04.12.2021)
Published in Open forum infectious diseases (04.12.2021)
Get full text
Journal Article
Reaction pathways of glucose oxidation by ozone under acidic conditions
Marcq, Olivier, Barbe, Jean-Michel, Trichet, Alain, Guilard, Roger
Published in Carbohydrate research (27.07.2009)
Published in Carbohydrate research (27.07.2009)
Get full text
Journal Article
NMR structural analysis of the capsular polysaccharide from Streptococcus pneumoniae serotype 6C
Cai, Ping, Moran, Justin, Pavliak, Viliam, Deng, Chenghua, Khoury, Nancy, Marcq, Olivier, Ruppen, Mark E
Published in Carbohydrate research (01.04.2012)
Published in Carbohydrate research (01.04.2012)
Get full text
Journal Article
NMR structural analysis of the capsular polysaccharide from Streptococcuspneumoniae serotype 6C
Cai, Ping, Moran, Justin, Pavliak, Viliam, Deng, Chenghua, Khoury, Nancy, Marcq, Olivier, Ruppen, Mark E.
Published in Carbohydrate research (01.04.2012)
Published in Carbohydrate research (01.04.2012)
Get full text
Journal Article
IMPROVED PROCESSES FOR PREPARING PEPTIDE CONJUGATES AND LINKERS
POZZO MARK JOHN, MARCQ OLIVIER J, MALONEY MARK THOMAS, TEIXEIRA JR. JOHN JOSEPH, MAGANO JAVIER, NADKARNI DURGESH VASANT
Year of Publication 03.11.2014
Get full text
Year of Publication 03.11.2014
Patent
IMPROVED METHODS FOR THE PREPARATION OF IMMUNOGENIC CONJUGATES
BEHRENS, Christopher, HEINRICHS, Jon, CHAN, Wei, FAIRMAN, Jeffery, MARCQ, Olivier
Year of Publication 09.01.2020
Get full text
Year of Publication 09.01.2020
Patent
CONJUGATED VACCINES
HEINRICHS, Jon H, FAIRMAN, Jeffery C, MARCQ, Olivier Jean Gérard, Behrens, Christopher R, CHAN, Wei
Year of Publication 20.02.2020
Get full text
Year of Publication 20.02.2020
Patent
IMPROVED PROCESSES FOR PREPARING PEPTIDE CONJUGATES AND LINKERS
MAGANO, JAVIER, POZZO, MARK JOHN, MALONEY, MARK THOMAS, MARCQ, OLIVIER J, NADKARNI, DURGESH VASANT, TEIXEIRA, JOHN JOSEPH, JR
Year of Publication 09.08.2016
Get full text
Year of Publication 09.08.2016
Patent
Processes for preparing peptide conjugates and linkers
POZZO MARK JOHN, TEIXEIRA, JR. JOHN JOSEPH, MARCQ OLIVIER J, MALONEY MARK THOMAS, MAGANO JAVIER, NADKARNI DURGESH VASANT
Year of Publication 31.05.2016
Get full text
Year of Publication 31.05.2016
Patent
Improved processes for preparing peptide conjugates and linkers
MAGANO, JAVIER, POZZO, MARK JOHN, TEIXEIRA JR., JOHN JOSEPH, MALONEY, MARK THOMAS, MARCQ, OLIVIER J, NADKARNI, DURGESH VASANT
Year of Publication 04.02.2016
Get full text
Year of Publication 04.02.2016
Patent
PROCESSES FOR PREPARING PEPTIDE CONJUGATES AND LINKERS
POZZO MARK JOHN, TEIXEIRA, JR. JOHN JOSEPH, MARCQ OLIVIER J, MALONEY MARK THOMAS, MAGANO JAVIER, NADKARNI DURGESH VASANT
Year of Publication 29.01.2015
Get full text
Year of Publication 29.01.2015
Patent
IMPROVED PROCESSES FOR PREPARING PEPTIDE CONJUGATES AND LINKERS
MAGANO, JAVIER, POZZO, MARK JOHN, TEIXEIRA, JR., JOHN JOSEPH, MALONEY, MARK THOMAS, MARCQ, OLIVIER J, NADKARNI, DURGESH VASANT
Year of Publication 29.10.2014
Get full text
Year of Publication 29.10.2014
Patent
IMPROVED PROCESSES FOR PREPARING PEPTIDE CONJUGATES AND LINKERS
MAGANO, JAVIER, POZZO, MARK JOHN, TEIXEIRA, JR., JOHN JOSEPH, MALONEY, MARK THOMAS, MARCQ, OLIVIER J, NADKARNI, DURGESH VASANT
Year of Publication 30.07.2014
Get full text
Year of Publication 30.07.2014
Patent