Tumor genomic, transcriptomic, and immune profiling characterizes differential response to first‐line platinum chemotherapy in high grade serous ovarian cancer
Weberpals, Johanne I., Pugh, Trevor J., Marco‐Casanova, Paola, Goss, Glenwood D., Andrews Wright, Natalie, Rath, Prisni, Torchia, Jonathon, Fortuna, Alexander, Jones, Gemma N., Roudier, Martine P., Bernard, Laurence, Lo, Bryan, Torti, Dax, Leon, Alberto, Marsh, Kayla, Hodgson, Darren, Duciaume, Marc, Howat, William J., Lukashchuk, Natalia, Lazic, Stanley E., Whelan, Doreen, Sekhon, Harmanjatinder S.
Published in Cancer medicine (Malden, MA) (01.05.2021)
Published in Cancer medicine (Malden, MA) (01.05.2021)
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Retrospective analysis of Schlafen11 (SLFN11) to predict the outcomes to therapies affecting the DNA damage response
Willis, Sophie E., Winkler, Claudia, Roudier, Martine P., Baird, Tarrion, Marco-Casanova, Paola, Jones, Emma V., Rowe, Philip, Rodriguez-Canales, Jaime, Angell, Helen K., Ng, Felicia S. L., Waring, Paul M., Hodgson, Darren, Ledermann, Jonathan A., Weberpals, Johanne I., Dean, Emma, Harrington, Elizabeth A., Barrett, J. Carl, Pierce, Andrew J., Leo, Elisabetta, Jones, Gemma N.
Published in British journal of cancer (07.12.2021)
Published in British journal of cancer (07.12.2021)
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The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
Damgaard, Rune Busk, Walker, Jennifer A., Marco-Casanova, Paola, Morgan, Neil V., Titheradge, Hannah L., Elliott, Paul R., McHale, Duncan, Maher, Eamonn R., McKenzie, Andrew N.J., Komander, David
Published in Cell (25.08.2016)
Published in Cell (25.08.2016)
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Molecular Basis and Regulation of OTULIN-LUBAC Interaction
Elliott, Paul R., Nielsen, Sofie V., Marco-Casanova, Paola, Fiil, Berthe Katrine, Keusekotten, Kirstin, Mailand, Niels, Freund, Stefan M.V., Gyrd-Hansen, Mads, Komander, David
Published in Molecular cell (08.05.2014)
Published in Molecular cell (08.05.2014)
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First-in-Human Study of AZD5153, A Small Molecule Inhibitor of Bromodomain Protein 4, in Patients with Relapsed/Refractory Malignant Solid Tumors and Lymphoma
Hamilton, Erika P, Wang, Judy S, Oza, Amit M, Patel, Manish R, Ulahannan, Susanna V, Bauer, Todd, Karlix, Janet L, Zeron-Medina, Jorge, Fabbri, Giulia, Marco-Casanova, Paola, Moorthy, Ganesh, Hattersley, Maureen M, Littlewood, Gillian M, Mitchell, Patrick D, Saeh, Jamal, Pouliot, Gayle P, Moore, Kathleen N
Published in Molecular cancer therapeutics (02.10.2023)
Published in Molecular cancer therapeutics (02.10.2023)
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Journal Article
The Sister Chromatid Exchange (SCE) Assay
Stults, Dawn M, Killen, Michael W, Marco-Casanova, Paola, Pierce, Andrew J
Published in Methods in molecular biology (Clifton, N.J.) (2020)
Published in Methods in molecular biology (Clifton, N.J.) (2020)
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Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis
Marco-Casanova, Paola, Lukashchuk, Natalia, Lombardi, Benedetta, Munugalavadla, Veerendra, Frigault, Melanie M., Harrington, Elizabeth A., Barrett, J. Carl, Pierce, Andrew J.
Published in Journal of visualized experiments (20.03.2021)
Published in Journal of visualized experiments (20.03.2021)
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Journal Article
Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis
Marco-Casanova, Paola, Lukashchuk, Natalia, Lombardi, Benedetta, Munugalavadla, Veerendra, Frigault, Melanie M, Harrington, Elizabeth A, Barrett, J Carl, Pierce, Andrew J
Published in Journal of visualized experiments (20.03.2021)
Published in Journal of visualized experiments (20.03.2021)
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Abstract 1649: Large scale multi-omics concordance study of cyclin E1 identifies high expressing tumors lacking CCNE1 gene alterations across multiple tumor indications
Willis, Sophie E., Jones, Gemma N., Gill, Shaan, Jones, Emma V., Raymond, Amelia, Nuttall, Barrett, Kirschner, Sophie, Gulati, Sakshi, Marco-Casanova, Paola, Lombardi, Benedetta, Jenkins, David, Ng, Felicia S., Hadfield, James, Waring, Paul, Angell, Helen K., Laman, Heike
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Tumor molecular profiling to differentiate extreme responses to first-line platinum-based chemotherapy in suboptimally debulked serous ovarian cancer patients
Weberpals, Johanne I, Pugh, Trevor, Goss, Glenwood D., Lo, Bryan, Andrews Wright, Natalie, Bernard, Laurence, Torti, Dax, Torchia, Jonathon, Rath, Prisni, Leon, Alberto, Marsh, Kayla, Hodgson, Darren R., Jones, Gemma N, Duciaume, Marc, Howat, William J, Marco-Casanova, Paola, Roudier, Martine P, Whelan, Doreen, Sekhon, Harmanjatinder S.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Targeted Mass Spectrometry Enables Quantification of Novel Pharmacodynamic Biomarkers of ATM Kinase Inhibition
Whiteaker, Jeffrey R, Wang, Tao, Zhao, Lei, Schoenherr, Regine M, Kennedy, Jacob J, Voytovich, Ulianna, Ivey, Richard G, Huang, Dongqing, Lin, Chenwei, Colantonio, Simona, Caceres, Tessa W, Roberts, Rhonda R, Knotts, Joseph G, Kaczmarczyk, Jan A, Blonder, Josip, Reading, Joshua J, Richardson, Christopher W, Hewitt, Stephen M, Garcia-Buntley, Sandra S, Bocik, William, Hiltke, Tara, Rodriguez, Henry, Harrington, Elizabeth A, Barrett, J Carl, Lombardi, Benedetta, Marco-Casanova, Paola, Pierce, Andrew J, Paulovich, Amanda G
Published in Cancers (30.07.2021)
Published in Cancers (30.07.2021)
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Abstract CT198: Immunomodulatory effects of the ATR inhibitor ceralasertib in a window of opportunity biomarker trial in patients with head and neck squamous cell carcinoma
Jones, Gemma N., Iyer, Sonia, Milo, Marta, Lou, Pei-Jen, Nance, Melonie A., Gomez-Roca, Carlos A., Standifer, Nathan, Marco-Casanova, Paola, Gill, Shaan, Surace, Michael, Bystry, Richard, Alexandrova, Maria, Willis, Sophie, Rodriguez-Canales, Jaime, Dannhorn, Andreas, Loembé, Bienvenu, Lau, Alan, Lukashchuk, Natalia, Harrington, Elizabeth A., Sanai, Elhan, Dean, Emma, Duvvuri, Umamaheswar
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Abstract CT269: A highly sensitive and specific PARylation assay confirms significant and durable target engagement by AZD5305 in patients
Lombardi, Benedetta, Marco-Casanova, Paola, Karapetsas, Athanasios, Hornett, Mya, Lukacs, Edit, Sugibayashi, Ko, Cosulich, Sabina, Dowson, Adam, Moorthy, Ganesh, Brown, Jessica, Yap, Timothy A., Schram, Alison M., Balmana, Judith, Luen, Stephen J., Im, Seock-Ah, Sharp, Adam, Baird, Richard, Harrington, Elizabeth A., Linardopoulos, Spiros
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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