Endoplasmic Reticulum Stress in Malignancy
Clarke, Hanna J., Chambers, Joseph E., Liniker, Elizabeth, Marciniak, Stefan J.
Published in Cancer cell (12.05.2014)
Published in Cancer cell (12.05.2014)
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Chloroquine Prevents Progression of Experimental Pulmonary Hypertension via Inhibition of Autophagy and Lysosomal Bone Morphogenetic Protein Type II Receptor Degradation
Long, Lu, Yang, Xudong, Southwood, Mark, Lu, Junyu, Marciniak, Stefan J, Dunmore, Benjamin J, Morrell, Nicholas W
Published in Circulation research (12.04.2013)
Published in Circulation research (12.04.2013)
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Role of unfolded proteins in lung disease
Bradley, Kirsty L, Stokes, Clare A, Marciniak, Stefan J, Parker, Lisa C, Condliffe, Alison M
Published in Thorax (01.01.2021)
Published in Thorax (01.01.2021)
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Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
Yusa, Kosuke, Rashid, S. Tamir, Strick-Marchand, Helene, Varela, Ignacio, Liu, Pei-Qi, Paschon, David E., Miranda, Elena, Ordóñez, Adriana, Hannan, Nicholas R. F., Rouhani, Foad J., Darche, Sylvie, Alexander, Graeme, Marciniak, Stefan J., Fusaki, Noemi, Hasegawa, Mamoru, Holmes, Michael C., Di Santo, James P., Lomas, David A., Bradley, Allan, Vallier, Ludovic
Published in Nature (London) (20.10.2011)
Published in Nature (London) (20.10.2011)
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PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz
Crespillo-Casado, Ana, Chambers, Joseph E, Fischer, Peter M, Marciniak, Stefan J, Ron, David
Published in eLife (27.04.2017)
Published in eLife (27.04.2017)
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Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers
Ordóñez, Adriana, Harding, Heather P., Marciniak, Stefan J., Ron, David
Published in Cell reports (Cambridge) (18.05.2021)
Published in Cell reports (Cambridge) (18.05.2021)
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The integrated stress response in pulmonary disease
Emanuelli, Giulia, Nassehzadeh-Tabriz, Nikou, Morrell, Nick W, Marciniak, Stefan J
Published in European respiratory review (30.09.2020)
Published in European respiratory review (30.09.2020)
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Biological basis for novel mesothelioma therapies
Obacz, Joanna, Yung, Henry, Shamseddin, Marie, Linnane, Emily, Liu, Xiewen, Azad, Arsalan A., Rassl, Doris M., Fairen-Jimenez, David, Rintoul, Robert C., Nikolić, Marko Z., Marciniak, Stefan J.
Published in British journal of cancer (12.10.2021)
Published in British journal of cancer (12.10.2021)
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Journal Article
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
Marciniak, Stefan J, Yun, Chi Y, Oyadomari, Seiichi, Novoa, Isabel, Zhang, Yuhong, Jungreis, Rivka, Nagata, Kazuhiro, Harding, Heather P, Ron, David
Published in Genes & development (15.12.2004)
Published in Genes & development (15.12.2004)
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Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system
Ulbrich, Lisa, Favaloro, Flores Lietta, Trobiani, Laura, Marchetti, Valentina, Patel, Vruti, Pascucci, Tiziana, Comoletti, Davide, Marciniak, Stefan J, De Jaco, Antonella
Published in Biochemical journal (15.02.2016)
Published in Biochemical journal (15.02.2016)
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Journal Article
hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency
Segeritz, Charis-Patricia, Rashid, Sheikh Tamir, de Brito, Miguel Cardoso, Serra, Maria Paola, Ordonez, Adriana, Morell, Carola Maria, Kaserman, Joseph E., Madrigal, Pedro, Hannan, Nicholas R.F., Gatto, Laurent, Tan, Lu, Wilson, Andrew A., Lilley, Kathryn, Marciniak, Stefan J., Gooptu, Bibek, Lomas, David A., Vallier, Ludovic
Published in Journal of hepatology (01.10.2018)
Published in Journal of hepatology (01.10.2018)
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Journal Article
Proteostasis During Cerebral Ischemia
Thiebaut, Audrey M, Hedou, Elodie, Marciniak, Stefan J, Vivien, Denis, Roussel, Benoit D
Published in Frontiers in neuroscience (19.06.2019)
Published in Frontiers in neuroscience (19.06.2019)
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Journal Article
Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells
van 't Wout, Emily F A, van Schadewijk, Annemarie, van Boxtel, Ria, Dalton, Lucy E, Clarke, Hanna J, Tommassen, Jan, Marciniak, Stefan J, Hiemstra, Pieter S
Published in PLoS pathogens (01.06.2015)
Published in PLoS pathogens (01.06.2015)
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Tissue expression of lactate transporters (MCT1 and MCT4) and prognosis of malignant pleural mesothelioma (brief report)
Dell'Anno, Irene, Barone, Elisa, Mutti, Luciano, Rassl, Doris M, Marciniak, Stefan J, Silvestri, Roberto, Landi, Stefano, Gemignani, Federica
Published in Journal of translational medicine (04.09.2020)
Published in Journal of translational medicine (04.09.2020)
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Journal Article
Pharmacological targeting of endoplasmic reticulum stress in disease
Marciniak, Stefan J., Chambers, Joseph E., Ron, David
Published in Nature reviews. Drug discovery (01.02.2022)
Published in Nature reviews. Drug discovery (01.02.2022)
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Endoplasmic Reticulum-associated Degradation (ERAD) and Autophagy Cooperate to Degrade Polymerogenic Mutant Serpins
Kroeger, Heike, Miranda, Elena, MacLeod, Ian, Pérez, Juan, Crowther, Damian C., Marciniak, Stefan J., Lomas, David A.
Published in The Journal of biological chemistry (21.08.2009)
Published in The Journal of biological chemistry (21.08.2009)
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