A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity
Barnett, Gillian C, Thompson, Deborah, Fachal, Laura, Kerns, Sarah, Talbot, Chris, Elliott, Rebecca M, Dorling, Leila, Coles, Charlotte E, Dearnaley, David P, Rosenstein, Barry S, Vega, Ana, Symonds, Paul, Yarnold, John, Baynes, Caroline, Michailidou, Kyriaki, Dennis, Joe, Tyrer, Jonathan P, Wilkinson, Jennifer S, Gómez-Caamaño, Antonio, Tanteles, George A, Platte, Radka, Mayes, Rebecca, Conroy, Don, Maranian, Mel, Luccarini, Craig, Gulliford, Sarah L, Sydes, Matthew R, Hall, Emma, Haviland, Joanne, Misra, Vivek, Titley, Jennifer, Bentzen, Søren M, Pharoah, Paul D.P, Burnet, Neil G, Dunning, Alison M, West, Catharine M.L
Published in Radiotherapy and oncology (01.05.2014)
Published in Radiotherapy and oncology (01.05.2014)
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Journal Article
CYP2D6 gene variants: association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen
Abraham, Jean E, Maranian, Mel J, Driver, Kristy E, Platte, Radka, Kalmyrzaev, Bolot, Baynes, Caroline, Luccarini, Craig, Shah, Mitul, Ingle, Susan, Greenberg, David, Earl, Helena M, Dunning, Alison M, Pharoah, Paul D P, Caldas, Carlos
Published in Breast cancer research : BCR (01.01.2010)
Published in Breast cancer research : BCR (01.01.2010)
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Journal Article
SDHC epi-mutation testing in gastrointestinal stromal tumours and related tumours in clinical practice
Casey, Ruth T., ten Hoopen, Rogier, Ochoa, Eguzkine, Challis, Benjamin G., Whitworth, James, Smith, Philip S., Martin, Jose Ezequiel, Clark, Graeme R., Rodger, Fay, Maranian, Mel, Allinson, Kieren, Madhu, Basetti, Roberts, Thomas, Campos, Luis, Anstee, Joanne, Park, Soo-Mi, Marker, Alison, Watts, Colin, Bulusu, Venkata R., Giger, Olivier T., Maher, Eamonn R.
Published in Scientific reports (15.07.2019)
Published in Scientific reports (15.07.2019)
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Journal Article
Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping
Abraham, Jean E, Maranian, Mel J, Spiteri, Inmaculada, Russell, Roslin, Ingle, Susan, Luccarini, Craig, Earl, Helena M, Pharoah, Paul P D, Dunning, Alison M, Caldas, Carlos
Published in BMC medical genomics (30.05.2012)
Published in BMC medical genomics (30.05.2012)
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Journal Article
Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1
Maranian, Mel J., Kar, Siddhartha, O’Reilly, Martin, Betts, Joshua A., Hillman, Kristine M., Kaufmann, Susanne, Canisius, Sander, Southey, Melissa C., Schmidt, Marjanka K., Hogervorst, Frans B., Muir, Kenneth, Ruebner, Matthias, Beckmann, Matthias W., Fletcher, Olivia, Bolla, Manjeet K., Wang, Qin, Sawyer, Elinor J., Tomlinson, Ian, Miller, Nicola, Burwinkel, Barbara, Yang, Rongxi, Surowy, Harald, Truong, Thérèse, Bojesen, Stig E., Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, González-Neira, Anna, Benitez, Javier, Brenner, Hermann, Dieffenbach, Aida Karina, Meindl, Alfons, Schmutzler, Rita K., Brauch, Hiltrud, Nevanlinna, Heli, Muranen, Taru A., Blomqvist, Carl, Bogdanova, Natalia V., Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Tseng, Chiu-chen, Van Den Berg, David, Lambrechts, Diether, Zhao, Hui, Weltens, Caroline, van Limbergen, Erik, Flesch-Janys, Dieter, Rudolph, Anja, Radice, Paolo, Capra, Fabio, Couch, Fergus J., Vachon, Celine, Haiman, Christopher A., Le Marchand, Loic, Simard, Jacques, Labrèche, France, Dumont, Martine, Teo, Soo Hwang, Ikram, M. Kamran, Kristensen, Vessela, Shrubsole, Martha, Kauppila, Saila, Andrulis, Irene L., Knight, Julia A., Glendon, Gord, Tchatchou, Sandrine, Tollenaar, Robert A.E.M., Van Asperen, Christi J., García-Closas, Montserrat, Figueroa, Jonine, Lissowska, Jolanta, Darabi, Hatef, Eriksson, Mikael, Martens, John W.M., Collée, J. Margriet, Shu, Xiao-Ou, Noh, Dong-Young, Hartman, Mikael, Hamann, Ute, Jaworska, Katarzyna, Durda, Katarzyna, Brennan, Paul, Olswold, Curtis, Slager, Susan, Yannoukakos, Drakoulis, Shen, Chen-Yang, Yu, Jyh-Cherng, Swerdlow, Anthony, Orr, Nick, Jones, Michael, Pita, Guillermo, Herrero, Daniel, Vincent, Daniel, Bacot, Francois, Ahmed, Shahana, Ponder, Bruce A.J., Chenevix-Trench, Georgia, Easton, Douglas F., French, Juliet D.
Published in American journal of human genetics (08.01.2015)
Published in American journal of human genetics (08.01.2015)
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Journal Article
CYP2D6 Gene Variants and Their Association with Breast Cancer Susceptibility
ABRAHAM, Jean E, MARANIAN, Mel J, CALDAS, Carlos, DRIVER, Kristy E, PLATTE, Radka, KALMYRZAEV, Bolot, BAYNES, Caroline, LUCCARINI, Craig, EARL, Helena M, DUNNING, Alison M, PHAROAH, Paul D. P
Published in Cancer epidemiology, biomarkers & prevention (01.06.2011)
Published in Cancer epidemiology, biomarkers & prevention (01.06.2011)
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Journal Article
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
Lindstrom, Sara, Dennis, Joe, Maranian, Mel J, Brand, Judith S, Nordestgaard, Børge G, Flyger, Henrik, Rahman, Nazneen, Fletcher, Olivia, Nevanlinna, Heli, Muranen, Taru A, Aaltonen, Kirsimari, Ahsan, Habibul, John, Esther M, Gammon, Marilie D, Ursin, Giske, Schmidt, Daniel F, Gapstur, Susan M, Gaudet, Mia M, Diver, W Ryan, Schumacher, Fredrick, Hoover, Robert N, Lambrechts, Diether, Wildiers, Hans, van Limbergen, Erik, Broeks, Annegien, Cornelissen, Sten, Couch, Fergus J, Olson, Janet E, Hallberg, Emily, Meijers-Heijboer, Hanne, Ito, Hidemi, Iwata, Hiroji, Guénel, Pascal, Sanchez, Marie, Marme, Frederik, Surowy, Harald, Sohn, Christof, Van Den Berg, David, Benitez, Javier, Lu, Wei, Gao, Yu-Tang, Andrulis, Irene L, Knight, Julia A, Mulligan, Anna Marie, Sawyer, Elinor J, Tomlinson, Ian, Kerin, Michael J, Lindblom, Annika, Hollestelle, Antoinette, Collée, J Margriet, Blot, William, Signorello, Lisa B, Cai, Qiuyin, Hou, Ming-Feng, Kristensen, Vessela N, Milne, Roger L, McLean, Catriona, Peeters, Petra, Khaw, Kay-Tee, Palli, Domenico, Mortensen, Lotte Maxild, Dossus, Laure, Meindl, Alfons, Sutter, Christian, Yang, Rongxi, Muir, Kenneth, Siriwanarangsan, Pornthep, Miao, Hui, Chia, Kee Seng, Chan, Ching Wan, Fasching, Peter A, Beckmann, Matthias W, Haeberle, Lothar, Brenner, Hermann, Stegmaier, Christa, Ashworth, Alan, Schoemaker, Minouk J, Brinton, Louise, Zheng, Wei, Grip, Mervi, Brauch, Hiltrud, Radice, Paolo, Manoukian, Siranoush, Bernard, Loris, Dörk, Thilo, Hartikainen, Jaana M, Tollenaar, Robert A E M, Seynaeve, Caroline, Van Asperen, Christi J, Brennan, Paul, McKay, James, Neuhausen, Susan L, Baynes, Caroline, Ahmed, Shahana, Healey, Catherine S, Herrero, Daniel, Simard, Jacques, Chenevix-Trench, Georgia, Hall, Per, Easton, Douglas F
Published in Nature genetics (01.04.2015)
Published in Nature genetics (01.04.2015)
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Journal Article
Genome-wide association study identifies five new breast cancer susceptibility loci
Turnbull, Clare, Ahmed, Shahana, Morrison, Jonathan, Pernet, David, Renwick, Anthony, Maranian, Mel, Seal, Sheila, Ghoussaini, Maya, Hines, Sarah, Healey, Catherine S, Hughes, Deborah, Warren-Perry, Margaret, Tapper, William, Eccles, Diana, Evans, D Gareth, Hooning, Maartje, Schutte, Mieke, van den Ouweland, Ans, Houlston, Richard, Ross, Gillian, Langford, Cordelia, Pharoah, Paul D P, Stratton, Michael R, Dunning, Alison M, Rahman, Nazneen, Easton, Douglas F
Published in Nature genetics (01.06.2010)
Published in Nature genetics (01.06.2010)
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Journal Article
Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers
Ghoussaini, Maya, Edwards, Stacey L., Meyer, Kerstin B., Ahmed, Shahana, Betts, Joshua A., Dicks, Ed, Beesley, Jonathan, Tyrer, Jonathan, Barnes, Daniel, Alonso, M. Rosario, Tessier, Daniel C., Luccarini, Craig, Baynes, Caroline, Bolla, Manjeet K., Wang, Qin, Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Verhoef, Senno, Cornelissen, Sten, Muir, Kenneth, Lophatananon, Artitaya, Siriwanarangsan, Pornthep, Loehberg, Christian R., Ekici, Arif B., dos Santos Silva, Isabel, Johnson, Nichola, Tomlinson, Ian, Truong, Thérèse, Menegaux, Florence, Bojesen, Stig E., Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, Milne, Roger L., Benitez, Javier, Anton-Culver, Hoda, Brenner, Hermann, Stegmaier, Christa, Meindl, Alfons, Aittomäki, Kristiina, Matsuo, Keitaro, Iwata, Hiroji, Antonenkova, Natalia N., Dörk, Thilo, Mannermaa, Arto, Stram, Daniel O., Floris, Giuseppe, Chang-Claude, Jenny, Rudolph, Anja, Radice, Paolo, Bonanni, Bernardo, Couch, Fergus J., Pankratz, Vernon S., Giles, Graham G., Severi, Gianluca, Haiman, Christopher A., Schumacher, Fredrick, Simard, Jacques, Goldberg, Mark S., Dumont, Martine, Teo, Soo Hwang, Yip, Cheng Har, Vithana, Eranga Nishanthie, Kristensen, Vessela, Zheng, Wei, Pylkäs, Katri, Glendon, Gord, Seynaeve, Caroline, Figueroa, Jonine, Lissowska, Jolanta, Schoof, Nils, Martens, John W.M., Collée, J. Margriet, Tilanus-Linthorst, Madeleine, Hall, Per, Humphreys, Keith, Shu, Xiao-Ou, Gao, Yu-Tang, Cai, Hui, Cox, Angela, Balasubramanian, Sabapathy P., Blot, William, Pharoah, Paul D.P., Healey, Catherine S., Pooley, Karen A., Yoo, Keun-Young, Miao, Hui, Sim, Xueling, Jaworska-Bieniek, Katarzyna, Gaborieau, Valerie, Toland, Amanda E., Chen, Shou-Tung, Swerdlow, Anthony, Ashworth, Alan, Schoemaker, Minouk J., Nevanlinna, Heli, Chenevix-Trench, Georgia, Easton, Douglas F., Dunning, Alison M.
Published in American journal of human genetics (04.04.2013)
Published in American journal of human genetics (04.04.2013)
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Journal Article
CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer
Thompson, Deborah J, O'Mara, Tracy A, Glubb, Dylan M, Painter, Jodie N, Cheng, Timothy, Folkerd, Elizabeth, Doody, Deborah, Dennis, Joe, Webb, Penelope M, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Michailidou, Kyriaki, Tyrer, Jonathan P, Maranian, Mel J, Hall, Per, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Fasching, Peter A, Hein, Alexander, Beckmann, Matthias W, Ekici, Arif B, Dörk, Thilo, Hillemanns, Peter, Dürst, Matthias, Runnebaum, Ingo, Zhao, Hui, Depreeuw, Jeroen, Schrauwen, Stefanie, Amant, Frederic, Goode, Ellen L, Fridley, Brooke L, Dowdy, Sean C, Winham, Stacey J, Salvesen, Helga B, Trovik, Jone, Njolstad, Tormund S, Werner, Henrica M J, Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Carvajal-Carmona, Luis, Tham, Emma, Liu, Tao, Mints, Miriam, Scott, Rodney J, McEvoy, Mark, Attia, John, Holliday, Elizabeth G, Montgomery, Grant W, Martin, Nicholas G, Nyholt, Dale R, Henders, Anjali K, Hopper, John L, Traficante, Nadia, Ruebner, Matthias, Swerdlow, Anthony J, Burwinkel, Barbara, Brenner, Hermann, Meindl, Alfons, Brauch, Hiltrud, Lindblom, Annika, Lambrechts, Diether, Chang-Claude, Jenny, Couch, Fergus J, Giles, Graham G, Kristensen, Vessela N, Cox, Angela, Bolla, Manjeet K, Wang, Qin, Bojesen, Stig E, Shah, Mitul, Luben, Robert, Khaw, Kay-Tee, Pharoah, Paul D P, Dunning, Alison M, Tomlinson, Ian, Dowsett, Mitch, Easton, Douglas F, Spurdle, Amanda B
Published in Endocrine-related cancer (01.02.2016)
Published in Endocrine-related cancer (01.02.2016)
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Journal Article
Germline whole exome sequencing and large-scale replication identifies FANCM as a likely high grade serous ovarian cancer susceptibility gene
Dicks, Ed, Song, Honglin, Ramus, Susan J, Oudenhove, Elke Van, Tyrer, Jonathan P, Intermaggio, Maria P, Kar, Siddhartha, Harrington, Patricia, Bowtell, David D, Group, Aocs Study, Cicek, Mine S, Cunningham, Julie M, Fridley, Brooke L, Alsop, Jennifer, Jimenez-Linan, Mercedes, Piskorz, Anna, Goranova, Teodora, Kent, Emma, Siddiqui, Nadeem, Paul, James, Crawford, Robin, Poblete, Samantha, Lele, Shashi, Sucheston-Campbell, Lara, Moysich, Kirsten B, Sieh, Weiva, McGuire, Valerie, Lester, Jenny, Odunsi, Kunle, Whittemore, Alice S, Bogdanova, Natalia, Dürst, Matthias, Hillemanns, Peter, Karlan, Beth Y, Gentry-Maharaj, Aleksandra, Menon, Usha, Tischkowitz, Marc, Levine, Douglas, Brenton, James D, Dörk, Thilo, Goode, Ellen L, Gayther, Simon A, Pharoah, D P Paul
Published in Oncotarget (01.08.2017)
Published in Oncotarget (01.08.2017)
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Journal Article
A High-Density Screen for Linkage in Multiple Sclerosis
Sawcer, Stephen, Ban, Maria, Maranian, Mel, Yeo, Tai Wai, Compston, Alastair, Kirby, Andrew, Daly, Mark J, De Jager, Philip L, Walsh, Emily, Lander, Eric S, Rioux, John D, Hafler, David A, Ivinson, Adrian, Rimmler, Jacqueline, Gregory, Simon G, Schmidt, Silke, Pericak-Vance, Margaret A, Akesson, Eva, Hillert, Jan, Datta, Pameli, Oturai, Annette, Ryder, Lars P, Harbo, Hanne F, Spurkland, Anne, Myhr, Kjell-Morten, Laaksonen, Mikko, Booth, David, Heard, Robert, Stewart, Graeme, Lincoln, Robin, Barcellos, Lisa F, Hauser, Stephen L, Oksenberg, Jorge R, Kenealy, Shannon J, Haines, Jonathan L
Published in American journal of human genetics (01.09.2005)
Published in American journal of human genetics (01.09.2005)
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Journal Article
A whole genome screen for linkage disequilibrium in multiple sclerosis confirms disease associations with regions previously linked to susceptibility
SAWCER, Stephen, MARANIAN, Mel, DEANS, Jackie, GOODFELLOW, Peter N, WALKER, Neil, CLAYTON, David, COMPSTON, Alastair, SETAKIS, Efrosini, CURWEN, Val, AKESSON, Eva, HENSIEK, Anke, CORADDU, Francesca, ROXBURGH, Richard, SAWCER, David, GRAY, Julia
Published in Brain (London, England : 1878) (01.06.2002)
Published in Brain (London, England : 1878) (01.06.2002)
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Journal Article
Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping
Sawcer, Stephen J, Maranian, Mel, Singlehurst, Sara, Yeo, TaiWai, Compston, Alastair, Daly, Mark J, De Jager, Philip L, Gabriel, Stacey, Hafler, David A, Ivinson, Adrian J, Lander, Eric S, Rioux, John D, Walsh, Emily, Gregory, Simon G, Schmidt, Silke, Pericak-Vance, Margaret A, Barcellos, Lisa, Hauser, Stephen L, Oksenberg, Jorge R, Kenealy, Shannon J, Haines, Jonathan L
Published in Human molecular genetics (01.09.2004)
Published in Human molecular genetics (01.09.2004)
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Journal Article
No evidence of a significant role for CTLA-4 in multiple sclerosis
Roxburgh, Richard H., Sawcer, Stephen, Maranian, Mel, Seaman, Shaun, Hensiek, Anke, Yeo, Taiwai, Deans, Jackie, Compston, Alastair
Published in Journal of neuroimmunology (01.02.2006)
Published in Journal of neuroimmunology (01.02.2006)
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Journal Article
Four single nucleotide polymorphisms from the vitamin D receptor gene in UK multiple sclerosis
Yeo, Tai Wai, Maranian, Mel, Singlehurst, Sara, Gray, Julia, Compston, Alastair, Sawcer, Stephen
Published in Journal of neurology (01.06.2004)
Published in Journal of neurology (01.06.2004)
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Journal Article
SELPLG and SELP single-nucleotide polymorphisms in multiple sclerosis
Fenoglio, Chiara, Galimberti, Daniela, Ban, Maria, Maranian, Mel, Scalabrini, Diego, Venturelli, Eliana, Piccio, Laura, De Riz, Milena, Yeo, Tai Wai, Goris, An, Gray, Julia, Bresolin, Nereo, Scarpini, Elio, Compston, Alastair, Sawcer, Stephen
Published in Neuroscience letters (13.02.2006)
Published in Neuroscience letters (13.02.2006)
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Journal Article
Refining the analysis of a whole genome linkage disequilibrium association map: the United Kingdom results
Yeo, Tai Wai, Roxburgh, Richard, Maranian, Mel, Singlehurst, Sara, Gray, Julia, Hensiek, Anke, Setakis, Efrosini, Compston, Alastair, Sawcer, Stephen
Published in Journal of neuroimmunology (01.10.2003)
Published in Journal of neuroimmunology (01.10.2003)
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