Initialising Customer-orientated Digital Transformation in Enterprises
von Leipzig, T., Gamp, M., Manz, D., Schöttle, K., Ohlhausen, P., Oosthuizen, G., Palm, D., von Leipzig, K.
Published in Procedia manufacturing (2017)
Published in Procedia manufacturing (2017)
Get full text
Journal Article
Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells
Szulcek, Robert, Sanchez-Duffhues, Gonzalo, Rol, Nina, Pan, Xiaoke, Tsonaka, Roula, Dickhoff, Chris, Yung, Lai Ming, Manz, Xue D., Kurakula, Kondababu, Kiełbasa, Szymon M., Mei, Hailiang, Timens, Wim, Yu, Paul B., Bogaard, Harm-Jan, Goumans, Marie-José
Published in Angiogenesis (London) (01.11.2020)
Published in Angiogenesis (London) (01.11.2020)
Get full text
Journal Article
Riociguat inhibits ultra‐large VWF string formation on pulmonary artery endothelial cells from chronic thromboembolic pulmonary hypertension patients
Jujo Sanada, Takayuki, Manz, Xue D., Symersky, Petr, Pan, Xiaoke, Yoshida, Keimei, Aman, Jurjan, Bogaard, Harm Jan
Published in Pulmonary circulation (01.10.2022)
Published in Pulmonary circulation (01.10.2022)
Get full text
Journal Article
C/EBPδ Suppresses Motility-Associated Gene Signatures and Reduces PDAC Cell Migration
Hartl, Leonie, Maarschalkerweerd, Pien A F, Butler, Joe M, Manz, Xue D, Thijssen, Victor L J L, Bijlsma, Maarten F, Duitman, JanWillem, Spek, C Arnold
Published in Cells (Basel, Switzerland) (22.10.2022)
Published in Cells (Basel, Switzerland) (22.10.2022)
Get full text
Journal Article
Regulation of VWF (Von Willebrand Factor) in Inflammatory Thrombosis
Manz, Xue D, Bogaard, Harm Jan, Aman, Jurjan
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2022)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2022)
Get full text
Journal Article
Development of a 3-Dimensional Model to Study Right Heart Dysfunction in Pulmonary Arterial Hypertension: First Observations
Llucià-Valldeperas, Aida, Smal, Rowan, Bekedam, Fjodor T, Cé, Margaux, Pan, Xiaoke, Manz, Xue D, Wijnker, Paul J M, Vonk-Noordegraaf, Anton, Bogaard, Harm J, Goumans, Marie-Jose, Man, Frances S de
Published in Cells (Basel, Switzerland) (20.12.2021)
Published in Cells (Basel, Switzerland) (20.12.2021)
Get full text
Journal Article
Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development
Donovan, Katherine A., Ferguson, Fleur M., Bushman, Jonathan W., Eleuteri, Nicholas A., Bhunia, Debabrata, Ryu, SeongShick, Tan, Li, Shi, Kun, Yue, Hong, Liu, Xiaoxi, Dobrovolsky, Dennis, Jiang, Baishan, Wang, Jinhua, Hao, Mingfeng, You, Inchul, Teng, Mingxing, Liang, Yanke, Hatcher, John, Li, Zhengnian, Manz, Theresa D., Groendyke, Brian, Hu, Wanyi, Nam, Yunju, Sengupta, Sandip, Cho, Hanna, Shin, Injae, Agius, Michael P., Ghobrial, Irene M., Ma, Michelle W., Che, Jianwei, Buhrlage, Sara J., Sim, Taebo, Gray, Nathanael S., Fischer, Eric S.
Published in Cell (10.12.2020)
Published in Cell (10.12.2020)
Get full text
Journal Article
Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
Koikawa, Kazuhiro, Kibe, Shin, Suizu, Futoshi, Sekino, Nobufumi, Kim, Nami, Manz, Theresa D., Pinch, Benika J., Akshinthala, Dipikaa, Verma, Ana, Gaglia, Giorgio, Nezu, Yutaka, Ke, Shizhong, Qiu, Chenxi, Ohuchida, Kenoki, Oda, Yoshinao, Lee, Tae Ho, Wegiel, Babara, Clohessy, John G., London, Nir, Santagata, Sandro, Wulf, Gerburg M., Hidalgo, Manuel, Muthuswamy, Senthil K., Nakamura, Masafumi, Gray, Nathanael S., Zhou, Xiao Zhen, Lu, Kun Ping
Published in Cell (02.09.2021)
Published in Cell (02.09.2021)
Get full text
Journal Article
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages
Hoepel, Willianne, Chen, Hung-Jen, Geyer, Chiara E, Allahverdiyeva, Sona, Manz, Xue D, de Taeye, Steven W, Aman, Jurjan, Mes, Lynn, Steenhuis, Maurice, Griffith, Guillermo R, Bonta, Peter I, Brouwer, Philip J M, Caniels, Tom G, van der Straten, Karlijn, Golebski, Korneliusz, Jonkers, René E, Larsen, Mads D, Linty, Federica, Nouta, Jan, van Roomen, Cindy P A A, van Baarle, Frank E H P, van Drunen, Cornelis M, Wolbink, Gertjan, Vlaar, Alexander P J, de Bree, Godelieve J, Sanders, Rogier W, Willemsen, Lisa, Neele, Annette E, van de Beek, Diederik, Rispens, Theo, Wuhrer, Manfred, Bogaard, Harm Jan, van Gils, Marit J, Vidarsson, Gestur, de Winther, Menno, den Dunnen, Jeroen
Published in Science Translational Medicine (02.06.2021)
Published in Science Translational Medicine (02.06.2021)
Get full text
Journal Article
Web Resource
Theoretical approach to estimate laser process parameters for drilling in crystalline silicon
Baier, T., Schulz-Ruthenberg, M., Ametowobla, M., Schlenker, T., Manz, D.
Published in Progress in photovoltaics (01.12.2010)
Published in Progress in photovoltaics (01.12.2010)
Get full text
Journal Article
Bone tissue engineering using 3D silk scaffolds and human dental pulp stromal cells epigenetic reprogrammed with the selective histone deacetylase inhibitor MI192
Man, Kenny, Joukhdar, Habib, Manz, Xue D., Brunet, Mathieu Y., Jiang, Lin-Hua, Rnjak-Kovacina, Jelena, Yang, Xuebin B.
Published in Cell and tissue research (01.06.2022)
Published in Cell and tissue research (01.06.2022)
Get full text
Journal Article
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo
Dubiella, Christian, Pinch, Benika J., Koikawa, Kazuhiro, Zaidman, Daniel, Poon, Evon, Manz, Theresa D., Nabet, Behnam, He, Shuning, Resnick, Efrat, Rogel, Adi, Langer, Ellen M., Daniel, Colin J., Seo, Hyuk-Soo, Chen, Ying, Adelmant, Guillaume, Sharifzadeh, Shabnam, Ficarro, Scott B., Jamin, Yann, Martins da Costa, Barbara, Zimmerman, Mark W., Lian, Xiaolan, Kibe, Shin, Kozono, Shingo, Doctor, Zainab M., Browne, Christopher M., Yang, Annan, Stoler-Barak, Liat, Shah, Richa B., Vangos, Nicholas E., Geffken, Ezekiel A., Oren, Roni, Koide, Eriko, Sidi, Samuel, Shulman, Ziv, Wang, Chu, Marto, Jarrod A., Dhe-Paganon, Sirano, Look, Thomas, Zhou, Xiao Zhen, Lu, Kun Ping, Sears, Rosalie C., Chesler, Louis, Gray, Nathanael S., London, Nir
Published in Nature chemical biology (01.09.2021)
Published in Nature chemical biology (01.09.2021)
Get full text
Journal Article
Identification of a potent and selective covalent Pin1 inhibitor
Pinch, Benika J., Doctor, Zainab M., Nabet, Behnam, Browne, Christopher M., Seo, Hyuk-Soo, Mohardt, Mikaela L., Kozono, Shingo, Lian, Xiaolan, Manz, Theresa D., Chun, Yujin, Kibe, Shin, Zaidman, Daniel, Daitchman, Dina, Yeoh, Zoe C., Vangos, Nicholas E., Geffken, Ezekiel A., Tan, Li, Ficarro, Scott B., London, Nir, Marto, Jarrod A., Buratowski, Stephen, Dhe-Paganon, Sirano, Zhou, Xiao Zhen, Lu, Kun Ping, Gray, Nathanael S.
Published in Nature chemical biology (01.09.2020)
Published in Nature chemical biology (01.09.2020)
Get full text
Journal Article
Epigenetic Modification of the von Willebrand Factor Promoter Drives Platelet Aggregation on the Pulmonary Endothelium in Chronic Thromboembolic Pulmonary Hypertension
Manz, Xue D, Szulcek, Robert, Pan, Xiaoke, Symersky, Petr, Dickhoff, Chris, Majolée, Jisca, Kremer, Veerle, Michielon, Elisabetta, Jordanova, Ekaterina S, Radonic, Teodora, Bijnsdorp, Irene V, Piersma, Sander R, Pham, Thang V, Jimenez, Connie R, Vonk Noordegraaf, Anton, de Man, Frances S, Boon, Reinier A, Voorberg, Jan, Hordijk, Peter L, Aman, Jurjan, Bogaard, Harm Jan
Published in American journal of respiratory and critical care medicine (01.04.2022)
Published in American journal of respiratory and critical care medicine (01.04.2022)
Get full text
Journal Article
Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors
Sivakumaren, Sindhu Carmen, Shim, Hyeseok, Zhang, Tinghu, Ferguson, Fleur M., Lundquist, Mark R., Browne, Christopher M., Seo, Hyuk-Soo, Paddock, Marcia N., Manz, Theresa D., Jiang, Baishan, Hao, Ming-Feng, Krishnan, Pranav, Wang, Diana G., Yang, T. Jonathan, Kwiatkowski, Nicholas P., Ficarro, Scott B., Cunningham, James M., Marto, Jarrod A., Dhe-Paganon, Sirano, Cantley, Lewis C., Gray, Nathanael S.
Published in Cell chemical biology (21.05.2020)
Published in Cell chemical biology (21.05.2020)
Get full text
Journal Article
Development of potent and selective degraders of PI5P4Kγ
Ji, Wenzhi, Wang, Eric S., Manz, Theresa D., Jiang, Jie, Donovan, Katherine A., Abulaiti, Xianmixinuer, Fischer, Eric S., Cantley, Lewis C., Zhang, Tinghu, Gray, Nathanael S.
Published in European journal of medicinal chemistry (05.02.2023)
Published in European journal of medicinal chemistry (05.02.2023)
Get full text
Journal Article
Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader
Teng, Mingxing, Jiang, Jie, Wang, Eric S., Geng, Qixiang, Toenjes, Sean T., Donovan, Katherine A., Mageed, Nada, Yue, Hong, Nowak, Radosław P., Wang, Jinhua, Manz, Theresa D., Fischer, Eric S., Cantley, Lewis C., Gray, Nathanael S.
Published in Angewandte Chemie International Edition (24.04.2023)
Published in Angewandte Chemie International Edition (24.04.2023)
Get full text
Journal Article
Discovery and Structure–Activity Relationship Study of (Z)‑5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5‑Phosphate 4‑Kinase Inhibitors
Manz, Theresa D, Sivakumaren, Sindhu Carmen, Ferguson, Fleur M, Zhang, Tinghu, Yasgar, Adam, Seo, Hyuk-Soo, Ficarro, Scott B, Card, Joseph D, Shim, Hyeseok, Miduturu, Chandrasekhar V, Simeonov, Anton, Shen, Min, Marto, Jarrod A, Dhe-Paganon, Sirano, Hall, Matthew D, Cantley, Lewis C, Gray, Nathanael S
Published in Journal of medicinal chemistry (14.05.2020)
Published in Journal of medicinal chemistry (14.05.2020)
Get full text
Journal Article
In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
Manz, Xue D., Albers, Hugo J., Symersky, Petr, Aman, Jurjan, van der Meer, Andries D., Bogaard, Harm Jan, Szulcek, Robert
Published in Journal of visualized experiments (24.05.2020)
Published in Journal of visualized experiments (24.05.2020)
Get full text
Journal Article