Hyperglycemia Enhances Cancer Immune Evasion by Inducing Alternative Macrophage Polarization through Increased O-GlcNAcylation
Rodrigues Mantuano, Natália, Stanczak, Michal A, Oliveira, Isadora de Araújo, Kirchhammer, Nicole, Filardy, Alessandra A, Monaco, Gianni, Santos, Ronan Christian, Fonseca, Agatha Carlos, Fontes, Miguel, Bastos, Jr, César de Souza, Dias, Wagner B, Zippelius, Alfred, Todeschini, Adriane R, Läubli, Heinz
Published in Cancer immunology research (01.10.2020)
Published in Cancer immunology research (01.10.2020)
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Journal Article
CD43 sialoglycoprotein modulates cardiac inflammation and murine susceptibility to Trypanosoma cruzi infection
Alisson-Silva, Frederico, Mantuano, Natália Rodrigues, Lopes, Ana Luiza, Vasconcelos-Dos-Santos, Andréia, Vale, André Macedo, Costa, Miriam Maria, Cannon, Judy L, Oliveira, Ana Carolina, Todeschini, Adriane R
Published in Scientific reports (13.06.2019)
Published in Scientific reports (13.06.2019)
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Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade
Stanczak, Michal A, Rodrigues Mantuano, Natalia, Kirchhammer, Nicole, Sanin, David E, Jacob, Francis, Coelho, Ricardo, Everest-Dass, Arun V, Wang, Jinyu, Trefny, Marcel P, Monaco, Gianni, Bärenwaldt, Anne, Gray, Melissa A, Petrone, Adam, Kashyap, Abhishek S, Glatz, Katharina, Kasenda, Benjamin, Normington, Karl, Broderick, James, Peng, Li, Pearce, Oliver M T, Pearce, Erika L, Bertozzi, Carolyn R, Zippelius, Alfred, Läubli, Heinz
Published in Science translational medicine (02.11.2022)
Published in Science translational medicine (02.11.2022)
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Expression of leukosialin (CD43) defines a major intrahepatic T cell subset associated with protective responses in visceral leishmaniasis
Nico, Dirlei, Maran, Naiara, Santos, Leonardo, Ramos-Junior, Erivan Schnaider, Mantuano, Natália Rodrigues, Coutinho, Joseane Lima Prado, Vale, Andre Macedo, Freire-de-Lima, Celio Geraldo, Todeschini, Adriane, Rodrigues, Juliany Cola Fernandes, Palatnik-de-Sousa, Clarisa Beatriz, Morrot, Alexandre
Published in Parasites & vectors (19.02.2015)
Published in Parasites & vectors (19.02.2015)
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Targeting the Siglec-sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma
Schmassmann, Philip, Roux, Julien, Buck, Alicia, Tatari, Nazanin, Hogan, Sabrina, Wang, Jinyu, Rodrigues Mantuano, Natalia, Wieboldt, Ronja, Lee, Sohyon, Snijder, Berend, Kaymak, Deniz, Martins, Tomás A, Ritz, Marie-Françoise, Shekarian, Tala, McDaid, Marta, Weller, Michael, Weiss, Tobias, Läubli, Heinz, Hutter, Gregor
Published in Science translational medicine (19.07.2023)
Published in Science translational medicine (19.07.2023)
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Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer
Vasconcelos-Dos-Santos, Andréia, Oliveira, Isadora A, Lucena, Miguel Clodomiro, Mantuano, Natalia Rodrigues, Whelan, Stephen A, Dias, Wagner Barbosa, Todeschini, Adriane Regina
Published in Frontiers in oncology (25.06.2015)
Published in Frontiers in oncology (25.06.2015)
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Detection of N-glycolyl-neuraminic acid-containing glycolipids in human skin
Manni, Michela, Mantuano, Natalia Rodrigues, Zingg, Andreas, Kappos, Elisabeth A, Behrens, Anna-Janina, Back, Jonathan, Follador, Rainer, Faridmoayer, Amir, Läubli, Heinz
Published in Frontiers in immunology (29.11.2023)
Published in Frontiers in immunology (29.11.2023)
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Melanoma Clonal Heterogeneity Leads to Secondary Resistance after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes
König, David, Sandholzer, Michael T, Uzun, Sarp, Zingg, Andreas, Ritschard, Reto, Thut, Helen, Glatz, Katharina, Kappos, Elisabeth A, Schaefer, Dirk J, Kettelhack, Christoph, Passweg, Jakob R, Holbro, Andreas, Baur, Katharina, Medinger, Michael, Buser, Andreas, Lardinois, Didier, Jeker, Lukas T, Khanna, Nina, Stenner, Frank, Kasenda, Benjamin, Homicsko, Krisztian, Matter, Matthias, Rodrigues Mantuano, Natalia, Zippelius, Alfred, Läubli, Heinz
Published in Cancer immunology research (02.07.2024)
Published in Cancer immunology research (02.07.2024)
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High-throughput T cell receptor engineering by functional screening identifies candidates with enhanced potency and specificity
Vazquez-Lombardi, Rodrigo, Jung, Johanna S., Schlatter, Fabrice S., Mei, Anna, Mantuano, Natalia Rodrigues, Bieberich, Florian, Hong, Kai-Lin, Kucharczyk, Jakub, Kapetanovic, Edo, Aznauryan, Erik, Weber, Cédric R., Zippelius, Alfred, Läubli, Heinz, Reddy, Sai T.
Published in Immunity (Cambridge, Mass.) (11.10.2022)
Published in Immunity (Cambridge, Mass.) (11.10.2022)
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Abstract LB-059: Hyperglycemia enhances cancer immune evasion by inducing alternative macrophage polarization through increased O-GlcNAcylation
Mantuano, Natalia Rodrigues, Stanczak, Michal, Oliveira, Isadora, Filardy, Alessandra, Silva, Ronan, Zippelius, Alfred, Todeschini, Adriane Regina, Laubli, Heinz
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibits anticancer immunity via CCL2
Wieboldt, Ronja, Sandholzer, Michael, Carlini, Emanuele, Lin, Chia-Wei, Börsch, Anastasiya, Zingg, Andreas, Lardinois, Didier, Herzig, Petra, Don, Leyla, Zippelius, Alfred, Läubli, Heinz, Mantuano, Natalia Rodrigues
Published in Cellular & molecular immunology (01.05.2024)
Published in Cellular & molecular immunology (01.05.2024)
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Evidences for the involvement of cell surface glycans in stem cell pluripotency and differentiation
Alisson-Silva, Frederico, de Carvalho Rodrigues, Deivid, Vairo, Leandro, Asensi, Karina Dutra, Vasconcelos-dos-Santos, Andréia, Mantuano, Natalia Rodrigues, Dias, Wagner Barbosa, Rondinelli, Edson, Goldenberg, Regina Coeli dos Santos, Urmenyi, Turán Peter, Todeschini, Adriane R
Published in Glycobiology (Oxford) (01.05.2014)
Published in Glycobiology (Oxford) (01.05.2014)
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Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Development Drugs Against Cancer
Andreia eVasconcelos-dos-Santos, Isadora A. Oliveira, Miguel Clodomiro Lucena, Natalia Rodrigues Mantuano, Stephen A. Whelan, Wagner Barbosa Dias, Adriane Regina Todeschini
Published in Frontiers in oncology (01.06.2015)
Published in Frontiers in oncology (01.06.2015)
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