In vitro pharmacology of L-158,809, a new highly potent and selective angiotensin II receptor antagonist
CHANG, R. S. L, SIEGL, P. K. S, CLINESCHMIDT, B. V, MANTLO, N. B, CHAKRAVARTY, P. K, GREENLEE, W. J, PATCHETT, A. A, LOTTI, V. J
Published in The Journal of pharmacology and experimental therapeutics (01.07.1992)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.1992)
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In vivo pharmacology of L-158,809, a new highly potent and selective nonpeptide angiotensin II receptor antagonist
SIEGL, P. K. S, CHANG, R. S. L, MANTLO, N. B, CHAKRAVARTY, P. K, ONDEYKA, D. L, GREENLEE, W. J, PATCHETT, A. A, SWEET, C. S, LOTTI, V. J
Published in The Journal of pharmacology and experimental therapeutics (01.07.1992)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.1992)
Journal Article
Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists
Mantlo, Nathan B, Chakravarty, Prasun K, Ondeyka, Debra L, Siegl, Peter K. S, Chang, Raymond S, Lotti, Victor J, Faust, Kristie A, Schorn, Terry W, Chen, Tsing Bau
Published in Journal of medicinal chemistry (01.09.1991)
Published in Journal of medicinal chemistry (01.09.1991)
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Journal Article
Effects of subtype-selective and balanced angiotensin II receptor antagonists in a porcine coronary artery model of vascular restenosis
HUCKLE, W. R, DRAG, M. D, MANTLO, N. B, CHANG, R. S. L, REILLY, C. F, SCHWARTZ, R. S, GREENLEE, W. J, JOHNSON, R. G, ACKER, W. R, POWERS, M, MCFALL, R. C, HOLDER, D. J, FUJITA, T, STABILITO, I. I, DOOSEOP KIM, ONDEYKA, D. L
Published in Circulation (New York, N.Y.) (01.03.1996)
Published in Circulation (New York, N.Y.) (01.03.1996)
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Journal Article
Evidence for a 1,2-hydride shift in the microsomal metabolism of the heterocycle L-158,338, a nonpeptide angiotensin II receptor antagonist
Stearns, R A, Miller, R R, Arison, B H, Rosegay, A, Smith, J L, Mantlo, N B, Chiu, S H
Published in Drug metabolism and disposition (01.07.1993)
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Published in Drug metabolism and disposition (01.07.1993)
Journal Article
Total synthesis of calicheamicinone: new arrangements for actuation of the reductive cycloaromatization of aglycon congeners
Haseltine, John N, Paz Cabal, Maria, Mantlo, Nathan B, Iwasawa, Nobuharu, Yamashita, Dennis S, Coleman, Robert S, Danishefsky, Samuel J, Schulte, Gayle K
Published in Journal of the American Chemical Society (01.05.1991)
Published in Journal of the American Chemical Society (01.05.1991)
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Journal Article
A CONCISE ROUTE TO THE CALICHEAMICIN-ESPERAMICIN SERIES - THE CRYSTAL-STRUCTURE OF A CORE SUBUNIT
DANISHEFSKY, SJ, MANTLO, NB, YAMASHITA, DS, SCHULTE, G
Published in Journal of the American Chemical Society (28.09.1988)
Published in Journal of the American Chemical Society (28.09.1988)
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Journal Article
AT1/AT2-BALANCED ANGIOTENSIN II ANTAGONISTS
Ashton, Wallace T., Chang, Linda L., Flanagan, Kelly L., Mantlo, Nathan B., Ondeyka, Debra L., Kim, Dooseop, de Laszlo, Stephen E., Glinka, Tomasz W., Rivero, Ralph A., Kevin, Nancy J., Chang, Raymond S.L., Siegl, Peter K.S., Kivlighn, Salah D., Greenlee, William J.
Published in European journal of medicinal chemistry (1995)
Published in European journal of medicinal chemistry (1995)
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Journal Article
Conference Proceeding
Evaluation of heterocyclic acid equivalents as tetrazole replacements in imidazopyridine-based nonpeptide angiotensin II receptor antagonists
Kim, Dooseop, Mantlo, Nathan B., Chang, R.S.L., Kivlighn, S.D., Greenlee, W.J.
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
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Journal Article
Angiotensin II receptor antagonists containing a phenylpyridine element
Mantlo, Nathan.B., Chang, Raymond S.L., Siegl, Peter.K.S.
Published in Bioorganic & medicinal chemistry letters (01.08.1993)
Published in Bioorganic & medicinal chemistry letters (01.08.1993)
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Journal Article
Design and Synthesis of a Potent and Selective Triazolone-Based Peroxisome Proliferator-Activated Receptor α Agonist
Xu, Yanping, Mayhugh, Daniel, Saeed, Ashraf, Wang, Xiaodong, Thompson, Richard C, Dominianni, Samuel J, Kauffman, Raymond F, Singh, Jaipal, Bean, James S, Bensch, William R, Barr, Robert J, Osborne, John, Montrose-Rafizadeh, Chahrzad, Zink, Richard W, Yumibe, Nathan P, Huang, Naijia, Luffer-Atlas, Debra, Rungta, Deepa, Maise, Dale E, Mantlo, Nathan B
Published in Journal of medicinal chemistry (20.11.2003)
Published in Journal of medicinal chemistry (20.11.2003)
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Journal Article
Imidazo[4,5-b]pyridine-based AT1/AT2 angiotensin II receptor antagonists
MANTLO, N. B, KIM, D, ONDEYKA, D, CHANG, R. S. L, KIVLIGHN, S. D, SIEGL, P. K. S, GREENLEE, W. J
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
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Journal Article
In vivo pharmacology of an angiotensin AT1 receptor antagonist with balanced affinity for angiotensin AT2 receptors
KIVLIGHN, S. D, ZINGARO, G. J, GABEL, R. A, BROTEN, T. P, CHANG, R. S. L, ONDEYKA, D. L, MANTLO, N. B, GIBSON, R. E, GRENLEE, W. J, SIEGL, P. K. S
Published in European journal of pharmacology (29.12.1995)
Published in European journal of pharmacology (29.12.1995)
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Journal Article
In vivo pharmacology of an angiotensin AT1 receptor antagonist with balanced affinity for AT2 receptors
Kivlighn, S D, Zingaro, G J, Gabel, R A, Broten, T P, Chang, R S, Ondeyka, D L, Mantlo, N B, Gibson, R E, Greenlee, W J, Siegl, P K
Published in European journal of pharmacology (29.12.1995)
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Published in European journal of pharmacology (29.12.1995)
Journal Article
In vitro pharmacology of an angiotensin AT1 receptor antagonist with balanced affinity for AT2 receptors
CHANG, R. S. L, LOTTI, V. J, MANTLO, N. B, TSING-BAU CHEN, O'MALLEY, S. S, BENDESKY, R. J, KLING, P. J, KIVLIGHN, S. D, SIEGL, P. K. S, ONDEYKA, D, GREENLEE, W. J
Published in European journal of pharmacology (29.12.1995)
Published in European journal of pharmacology (29.12.1995)
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Journal Article
Acidic phenols: a new class of potent nonpeptide angiotensin II receptor antagonits
DOOSEOP KIM, MANTLO, N. B, SCHECK, S, ZINGARO, G. J, KIVLIGHN, S. D, GREENLEE, W. J, TATA, J. R, FITCH, K, DHANOA, D, OWENS, K, LEVORSE, D, SIEGL, P. K. S, CHANG, R. S. L, CHEN, T
Published in Bioorganic & medicinal chemistry letters (1994)
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Published in Bioorganic & medicinal chemistry letters (1994)
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