The Role of HMGB1, a Nuclear Damage-Associated Molecular Pattern Molecule, in the Pathogenesis of Lung Diseases
Wang, Mao, Gauthier, Alex, Daley, LeeAnne, Dial, Katelyn, Wu, Jiaqi, Woo, Joanna, Lin, Mosi, Ashby, Charles, Mantell, Lin L
Published in Antioxidants & redox signaling (01.11.2019)
Published in Antioxidants & redox signaling (01.11.2019)
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Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1
Patel, Vivek, Dial, Katelyn, Wu, Jiaqi, Gauthier, Alex G, Wu, Wenjun, Lin, Mosi, Espey, Michael G, Thomas, Douglas D, Ashby, Jr, Charles R, Mantell, Lin L
Published in International journal of molecular sciences (01.02.2020)
Published in International journal of molecular sciences (01.02.2020)
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Carbon Nanomaterials Stimulate HMGB1 Release From Macrophages and Induce Cell Migration and Invasion
Cui, Xuejing, Wan, Bin, Yang, Yu, Xin, Yan, Xie, Yi-Chun, Guo, Liang-Hong, Mantell, Lin L
Published in Toxicological sciences (01.12.2019)
Published in Toxicological sciences (01.12.2019)
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Dual effects of supplemental oxygen on pulmonary infection, inflammatory lung injury, and neuromodulation in aging and COVID-19
Lin, Mosi, Stewart, Maleka T., Zefi, Sidorela, Mateti, Kranthi Venkat, Gauthier, Alex, Sharma, Bharti, Martinez, Lauren R., Ashby, Charles R., Mantell, Lin L.
Published in Free radical biology & medicine (01.09.2022)
Published in Free radical biology & medicine (01.09.2022)
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The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation
Sitapara, Ravikumar A, Gauthier, Alex G, Valdés-Ferrer, Sergio I, Lin, Mosi, Patel, Vivek, Wang, Mao, Martino, Ashley T, Perron, Jeanette C, Ashby, Jr, Charles R, Tracey, Kevin J, Pavlov, Valentin A, Mantell, Lin L
Published in Molecular medicine (Cambridge, Mass.) (29.06.2020)
Published in Molecular medicine (Cambridge, Mass.) (29.06.2020)
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A Standardized Botanical Composition Mitigated Acute Inflammatory Lung Injury and Reduced Mortality through Extracellular HMGB1 Reduction
Yimam, Mesfin, Horm, Teresa, O’Neal, Alexandria, Jiao, Ping, Hong, Mei, Brownell, Lidia, Jia, Qi, Lin, Mosi, Gauthier, Alex, Wu, Jiaqi, Venkat Mateti, Kranti, Yang, Xiaojian, Dial, Katelyn, Zefi, Sidorela, Mantell, Lin L
Published in Molecules (Basel, Switzerland) (01.09.2023)
Published in Molecules (Basel, Switzerland) (01.09.2023)
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The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function
Sitapara, Ravikumar A, Gauthier, Alex G, Patel, Vivek S, Lin, Mosi, Zur, Michelle, Ashby, Charles R, Mantell, Lin L
Published in Molecular medicine (Cambridge, Mass.) (01.12.2020)
Published in Molecular medicine (Cambridge, Mass.) (01.12.2020)
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The nitric oxide donor, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate (DETA-NONOate/D-NO), increases survival by attenuating hyperoxia-compromised innate immunity in bacterial clearance in a mouse model of ventilator-associated pneumonia
Gore, Ashwini, Gauthier, Alex G., Lin, Mosi, Patel, Vivek, Thomas, Douglas D., Ashby, Charles R., Mantell, Lin L.
Published in Biochemical pharmacology (01.06.2020)
Published in Biochemical pharmacology (01.06.2020)
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Correction to: GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function
Sitapara, Ravikumar A., Gauthier, Alex G., Patel, Vivek S., Lin, Mosi, Zur, Michelle, Ashby, Charles R., Mantell, Lin L.
Published in Molecular medicine (Cambridge, Mass.) (23.08.2021)
Published in Molecular medicine (Cambridge, Mass.) (23.08.2021)
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Journal Article
From nicotine to the cholinergic anti-inflammatory reflex - Can nicotine alleviate the dysregulated inflammation in COVID-19?
Gauthier, Alex G., Lin, Mosi, Wu, Jiaqi, Kennedy, Thomas P., Daley, Lee-Anne, Ashby, Charles R., Mantell, Lin L.
Published in Journal of immunotoxicology (01.01.2021)
Published in Journal of immunotoxicology (01.01.2021)
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Journal Article
Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications
Vasudevan, Divya, Hickok, Jason R, Bovee, Rhea C, Pham, Vy, Mantell, Lin L, Bahroos, Neil, Kanabar, Pinal, Cao, Xing-Jun, Maienschein-Cline, Mark, Garcia, Benjamin A, Thomas, Douglas D
Published in Cancer research (Chicago, Ill.) (15.12.2015)
Published in Cancer research (Chicago, Ill.) (15.12.2015)
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2-O, 3-O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1-compromised macrophage function
Wang, Mao, Gauthier, Alex G, Kennedy, Thomas P, Wang, Haichao, Velagapudi, Uday Kiran, Talele, Tanaji T, Lin, Mosi, Wu, Jiaqi, Daley, LeeAnne, Yang, Xiaojing, Patel, Vivek, Mun, Sung Soo, Ashby, Jr, Charles R, Mantell, Lin L
Published in Molecular medicine (Cambridge, Mass.) (16.07.2021)
Published in Molecular medicine (Cambridge, Mass.) (16.07.2021)
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Retraction Note: The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function
Sitapara, Ravikumar A, Antoine, Daniel J, Sharma, Lokesh, Patel, Vivek S, Ashby, Jr, Charles R, Gorasiya, Samir, Yang, Huan, Zur, Michelle, Mantell, Lin L
Published in Molecular medicine (Cambridge, Mass.) (30.12.2020)
Published in Molecular medicine (Cambridge, Mass.) (30.12.2020)
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Hyperoxia sensing: From molecular mechanisms to significance in disease
Gore, Ashwini, Muralidhar, Maitreyi, Espey, Michael Graham, Degenhardt, Kurt, Mantell, Lin L.
Published in Journal of immunotoxicology (01.12.2010)
Published in Journal of immunotoxicology (01.12.2010)
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Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury
Entezari, Maria, Javdan, Mohammad, Antoine, Daniel J, Morrow, Dympna M P, Sitapara, Ravikumar A, Patel, Vivek, Wang, Mao, Sharma, Lokesh, Gorasiya, Samir, Zur, Michelle, Wu, Wenjun, Li, Jianhua, Yang, Huan, Ashby, Charles R, Thomas, Douglas, Wang, Haichao, Mantell, Lin L
Published in Redox biology (01.01.2014)
Published in Redox biology (01.01.2014)
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GAT107-mediated α7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by alleviating macrophage mitochondrial oxidative stress via reducing MnSOD-S-glutathionylation
Gauthier, Alex G., Lin, Mosi, Zefi, Sidorela, Kulkarni, Abhijit, Thakur, Ganesh A., Ashby, Charles R., Mantell, Lin L.
Published in Redox biology (01.04.2023)
Published in Redox biology (01.04.2023)
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Correction to: 2‑O, 3‑O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1‑compromised macrophage function
Wang, Mao, Gauthier, Alex G., Kennedy, Thomas P., Wang, Haichao, Velagapudi, Uday Kiran, Talele, Tanaji T., Lin, Mosi, Wu, Jiaqi, Daley, LeeAnne, Yang, Xiaojing, Patel, Vivek, Mun, Sung Soo, Ashby, Charles R., Mantell, Lin L.
Published in Molecular medicine (Cambridge, Mass.) (03.09.2021)
Published in Molecular medicine (Cambridge, Mass.) (03.09.2021)
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Expression of Concern to: The α7 nicotine acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function
Sitapara, Ravikumar A, Antoine, Daniel J, Sharma, Lokesh, Patel, Vivek S, Ashby, Jr, Charles R, Gorasiya, Samir, Yang, Huan, Zur, Michelle, Mantell, Lin L
Published in Molecular medicine (Cambridge, Mass.) (03.02.2020)
Published in Molecular medicine (Cambridge, Mass.) (03.02.2020)
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Journal Article
The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function
Sitapara, Ravikumar A, Antoine, Daniel J, Sharma, Lokesh, Patel, Vivek S, Ashby, Jr, Charles R, Gorasiya, Samir, Yang, Huan, Zur, Michelle, Mantell, Lin L
Published in Molecular medicine (Cambridge, Mass.) (19.06.2014)
Published in Molecular medicine (Cambridge, Mass.) (19.06.2014)
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Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis
Entezari, Maria, Weiss, Daniel J, Sitapara, Ravikumar, Whittaker, Laurie, Wargo, Matthew J, Li, JianHua, Wang, Haichao, Yang, Huan, Sharma, Lokesh, Phan, Binh D, Javdan, Mohammad, Chavan, Sangeeta S, Miller, Edmund J, Tracey, Kevin J, Mantell, Lin L
Published in Molecular medicine (Cambridge, Mass.) (09.05.2012)
Published in Molecular medicine (Cambridge, Mass.) (09.05.2012)
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