Search Results - "Manssour Fraga, Carlos Alberto" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders II: Alzheimer's disease

The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders II: Alzheimer's disease

by da Rocha, Miguel Divino, Viegas, Flávia Pereira Dias, Campos, Helineide Cristina, Nicastro, Patrícia Carolina, Fossaluzza, Poliana Calve, Fraga, Carlos Alberto Manssour, Barreiro, Eliezer J, Viegas, Jr, Claudio
Published in CNS & neurological disorders drug targets (01.03.2011)

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Molecular Hybridization: A Useful Tool in the Design of New Drug Prototypes

Molecular Hybridization: A Useful Tool in the Design of New Drug Prototypes

by VIEGAS-JUNIOR, Claudio, DANUELLO, Amanda, DA SILVA BOLZANI, Vanderlan, BARREIRO, Eliezer J, MANSSOUR FRAGA, Carlos Alberto
Published in Current medicinal chemistry (01.07.2007)

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The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders I: Parkinson's disease

The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders I: Parkinson's disease

by Campos, Helineide Cristina, da Rocha, Miguel Divino, Viegas, Flávia Pereira Dias, Nicastro, Patrícia Carolina, Fossaluzza, Poliana Calve, Fraga, Carlos Alberto Manssour, Barreiro, Eliezer J, Viegas, Jr, Claudio
Published in CNS & neurological disorders drug targets (01.03.2011)

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Novel Regioisomeric Analogues of Naphthyl-N-Acylhydrazone Derivatives and Their Anti-Inflammatory Effects

Novel Regioisomeric Analogues of Naphthyl-N-Acylhydrazone Derivatives and Their Anti-Inflammatory Effects

by da Costa Salomé, Dayana, de Freitas, Rosana Helena Coimbra Nogueira, Fraga, Carlos Alberto Manssour, Fernandes, Patricia Dias
Published in International journal of molecular sciences (01.11.2022)

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ROCK inhibition with Fasudil induces beta-catenin nuclear translocation and inhibits cell migration of MDA-MB 231 human breast cancer cells

ROCK inhibition with Fasudil induces beta-catenin nuclear translocation and inhibits cell migration of MDA-MB 231 human breast cancer cells

by Guerra, Fabiana Sélos, Oliveira, Ramon Guerra de, Fraga, Carlos Alberto Manssour, Mermelstein, Claudia Dos Santos, Fernandes, Patricia Dias
Published in Scientific reports (20.10.2017)

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Anti-atherogenic Effects of a New Thienylacylhydrazone Derivative, LASSBio-788, in Rats Fed a Hypercholesterolemic Diet

Anti-atherogenic Effects of a New Thienylacylhydrazone Derivative, LASSBio-788, in Rats Fed a Hypercholesterolemic Diet

by da Motta, Nadia Alice Vieira, Kümmerle, Arthur Eugen, Marostica, Elisabeth, dos Santos, Caroline Fernandes, Manssour Fraga, Carlos Alberto, Barreiro, Eliezer Jesus, de Miranda, Ana Luisa Palhares, de Brito, Fernanda Carla Ferreira
Published in Journal of Pharmacological Sciences (2013)

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Characterization of amide bond conformers for a novel heterocyclic template of N-acylhydrazone derivatives

Characterization of amide bond conformers for a novel heterocyclic template of N-acylhydrazone derivatives

by Lopes, Alexandra Basilio, Miguez, Eduardo, Kümmerle, Arthur Eugen, Rumjanek, Victor Marcos, Fraga, Carlos Alberto Manssour, Barreiro, Eliezer J
Published in Molecules (Basel, Switzerland) (25.09.2013)

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New 2-amino-pyridinyl-N-acylhydrazones: Synthesis and identification of their mechanism of anti-inflammatory action

New 2-amino-pyridinyl-N-acylhydrazones: Synthesis and identification of their mechanism of anti-inflammatory action

by Cordeiro, Natalia de Morais, Freitas, Rosana H.C.N., Fraga, Carlos Alberto Manssour, Fernandes, Patricia Dias
Published in Biomedicine & pharmacotherapy (01.03.2020)

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An Unusual Intramolecular Halogen Bond Guides Conformational Selection

An Unusual Intramolecular Halogen Bond Guides Conformational Selection

by Tesch, Roberta, Becker, Christian, Müller, Matthias Philipp, Beck, Michael Edmund, Quambusch, Lena, Getlik, Matthäus, Lategahn, Jonas, Uhlenbrock, Niklas, Costa, Fanny Nascimento, Polêto, Marcelo D., Pinheiro, Pedro de Sena Murteira, Rodrigues, Daniel Alencar, Sant'Anna, Carlos Mauricio R., Ferreira, Fabio Furlan, Verli, Hugo, Fraga, Carlos Alberto Manssour, Rauh, Daniel
Published in Angewandte Chemie International Edition (26.07.2018)

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Modeling zinc‐oxygen coordination in histone deacetylase: A comparison of semiempirical methods performance

Modeling zinc‐oxygen coordination in histone deacetylase: A comparison of semiempirical methods performance

by Pinheiro, Pedro de Sena Murteira, Rodrigues, Daniel Alencar, Sant'Anna, Carlos Mauricio R., Fraga, Carlos Alberto Manssour
Published in International journal of quantum chemistry (05.11.2018)

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Theoretical and experimental characterization of 1,4-N⋯S σ-hole intramolecular interactions in bioactive N -acylhydrazone derivatives

Theoretical and experimental characterization of 1,4-N⋯S σ-hole intramolecular interactions in bioactive N -acylhydrazone derivatives

by Pinheiro, Pedro de Sena Murteira, Rodrigues, Daniel Alencar, Alves, Marina Amaral, Tinoco, Luzineide Wanderley, Ferreira, Glaucio Braga, de Sant’Anna, Carlos Mauricio Rabello, Fraga, Carlos Alberto Manssour
Published in New journal of chemistry (2018)

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Novel p38 Mitogen-Activated Protein Kinase Inhibitor Reverses Hypoxia-Induced Pulmonary Arterial Hypertension in Rats

Novel p38 Mitogen-Activated Protein Kinase Inhibitor Reverses Hypoxia-Induced Pulmonary Arterial Hypertension in Rats

by Silva, Grazielle Fernandes, da Silva, Jaqueline Soares, de Alencar, Allan Kardec Nogueira, de Moraes Carvalho da Silva, Marina, Montagnoli, Tadeu Lima, de Souza Rocha, Bruna, de Freitas, Rosana Helena Coimbra Nogueira, Sudo, Roberto Takashi, Fraga, Carlos Alberto Manssour, Zapata-Sudo, Gisele
Published in Pharmaceuticals (Basel, Switzerland) (21.07.2022)

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Investigating the Molecular Basis for the Selective Inhibition of Aldehyde Dehydrogenase 2 by the Isoflavonoid Daidzin

Investigating the Molecular Basis for the Selective Inhibition of Aldehyde Dehydrogenase 2 by the Isoflavonoid Daidzin

by da Silva Cunha, Thayssa Tavares, de Souza, Felipe Rodrigues, de Sena Murteira Pinheiro, Pedro, de Sant'Anna, Carlos Maurício Rabello, Noël, François, Costa França, Tanos Celmar, Manssour Fraga, Carlos Alberto
Published in CNS & neurological disorders drug targets (01.01.2020)

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Imidazole: Synthesis, Functionalization and Physicochemical Properties of a Privileged Structure in Medicinal Chemistry

Imidazole: Synthesis, Functionalization and Physicochemical Properties of a Privileged Structure in Medicinal Chemistry

by Tolomeu, Heber Victor, Fraga, Carlos Alberto Manssour
Published in Molecules (Basel, Switzerland) (13.01.2023)

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Antiprotozoal activity of (E)-cinnamic N-acylhydrazone derivatives

Antiprotozoal activity of (E)-cinnamic N-acylhydrazone derivatives

by Carvalho, Samir Aquino, Kaiser, Marcel, Brun, Reto, da Silva, Edson Ferreira, Fraga, Carlos Alberto Manssour
Published in Molecules (Basel, Switzerland) (05.12.2014)

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Synthesis and pharmacological evaluation of novel isoquinoline N-sulphonylhydrazones designed as ROCK inhibitors

Synthesis and pharmacological evaluation of novel isoquinoline N-sulphonylhydrazones designed as ROCK inhibitors

by Oliveira, Ramon Guerra de, Guerra, Fabiana Sélos, Mermelstein, Cláudia dos Santos, Fernandes, Patrícia Dias, Bastos, Isadora Tairinne de Sena, Costa, Fanny Nascimento, Barroso, Regina Cely Rodrigues, Ferreira, Fabio Furlan, Fraga, Carlos Alberto Manssour
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2018)

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Vasodilator and antihypertensive effects of a novel N-acylhydrazone derivative mediated by the inhibition of L-type Ca2+ channels

Vasodilator and antihypertensive effects of a novel N-acylhydrazone derivative mediated by the inhibition of L-type Ca2+ channels

by Pereira, Sharlene Lopes, Kummerle, Arthur Eugen, Fraga, Carlos Alberto Manssour, Barreiro, Eliezer Jesus, Sudo, Roberto Takashi, Zapata-Sudo, Gisele
Published in Fundamental & clinical pharmacology (01.02.2014)

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The Outcomes of Small-Molecule Kinase Inhibitors and the Role of ROCK2 as a Molecular Target for the Treatment of Alzheimer's Disease

The Outcomes of Small-Molecule Kinase Inhibitors and the Role of ROCK2 as a Molecular Target for the Treatment of Alzheimer's Disease

by Tolomeu, Heber Victor, Fraga, Carlos Alberto Manssour
Published in CNS & neurological disorders drug targets (01.01.2022)

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The Magic Methyl and Its Tricks in Drug Discovery and Development

The Magic Methyl and Its Tricks in Drug Discovery and Development

by Pinheiro, Pedro de Sena Murteira, Franco, Lucas Silva, Fraga, Carlos Alberto Manssour
Published in Pharmaceuticals (Basel, Switzerland) (01.08.2023)

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Histone deacetylase inhibition mitigates cognitive deficits and astrocyte dysfunction induced by amyloid-β (Aβ) oligomers

Histone deacetylase inhibition mitigates cognitive deficits and astrocyte dysfunction induced by amyloid-β (Aβ) oligomers

by Diniz, Luan Pereira, Morgado, Juliana, Bergamo Araujo, Ana Paula, da Silva Antônio, Leticia Maria, Mota-Araujo, Hannah Paola, de Sena Murteira Pinheiro, Pedro, Sagrillo, Fernanda Savacini, Cesar, Gabriele Vargas, Ferreira, Sérgio T, Figueiredo, Cláudia Pinto, Manssour Fraga, Carlos Alberto, Gomes, Flávia Carvalho Alcantara
Published in British journal of pharmacology (27.06.2024)

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