High-affinity agonism at the P2X7 receptor is mediated by three residues outside the orthosteric pocket
Oken, Adam C., Lisi, Nicolas E., Krishnamurthy, Ipsita, McCarthy, Alanna E., Godsey, Michael H., Glasfeld, Arthur, Mansoor, Steven E.
Published in Nature communications (06.08.2024)
Published in Nature communications (06.08.2024)
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Cryo-EM structures of the human P2X1 receptor reveal subtype-specific architecture and antagonism by supramolecular ligand-binding
Oken, Adam C., Lisi, Nicolas E., Ditter, Ismayn A., Shi, Haoyuan, Nechiporuk, Nadia A., Mansoor, Steven E.
Published in Nature communications (01.10.2024)
Published in Nature communications (01.10.2024)
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X-ray structures define human P2X3 receptor gating cycle and antagonist action
Mansoor, Steven E., Lü, Wei, Oosterheert, Wout, Shekhar, Mrinal, Tajkhorshid, Emad, Gouaux, Eric
Published in Nature (London) (06.10.2016)
Published in Nature (London) (06.10.2016)
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X-ray structures define human P2X(3) receptor gating cycle and antagonist action
Mansoor, Steven E, Lü, Wei, Oosterheert, Wout, Shekhar, Mrinal, Tajkhorshid, Emad, Gouaux, Eric
Published in Nature (London) (06.10.2016)
Published in Nature (London) (06.10.2016)
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Rhodopsin Self-Associates in Asolectin Liposomes
Mansoor, Steven E., Palczewski, Krzysztof, Farrens, David L.
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2006)
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P2X 7 receptors exhibit at least three modes of allosteric antagonism
Oken, Adam C, Ditter, Ismayn A, Lisi, Nicolas E, Krishnamurthy, Ipsita, Godsey, Michael H, Mansoor, Steven E
Published in Science advances (04.10.2024)
Published in Science advances (04.10.2024)
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Journal Article
P2X7 receptors exhibit at least three modes of allosteric antagonism
Oken, Adam C, Ditter, Ismayn A, Lisi, Nicolas E, Krishnamurthy, Ipsita, Godsey, Michael H, Mansoor, Steven E
Published in Science advances (04.10.2024)
Published in Science advances (04.10.2024)
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Determination of Protein Secondary Structure and Solvent Accessibility Using Site-Directed Fluorescence Labeling. Studies of T4 Lysozyme Using the Fluorescent Probe Monobromobimane
Mansoor, Steven E, Mchaourab, Hassane S, Farrens, David L
Published in Biochemistry (Easton) (07.12.1999)
Published in Biochemistry (Easton) (07.12.1999)
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Molecular pharmacology of the P2X7 receptor revealed by cryo-EM
Oken, Adam C., Lisi, Nicolas E., Krishnamurthy, Ipsita, McCarthy, Alanna E., Godsey, Michael H., Mansoor, Steven E.
Published in Biophysical journal (08.02.2024)
Published in Biophysical journal (08.02.2024)
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