Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart
Thapa, Dharendra, Zhang, Manling, Manning, Janet R, Guimarães, Danielle A, Stoner, Michael W, O'Doherty, Robert M, Shiva, Sruti, Scott, Iain
Published in American journal of physiology. Heart and circulatory physiology (01.08.2017)
Published in American journal of physiology. Heart and circulatory physiology (01.08.2017)
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Journal Article
GPER-dependent estrogen signaling increases cardiac GCN5L1 expression
Manning, Janet R, Thapa, Dharendra, Zhang, Manling, Stoner, Michael W, Sembrat, John C, Rojas, Mauricio, Scott, Iain
Published in American journal of physiology. Heart and circulatory physiology (01.05.2022)
Published in American journal of physiology. Heart and circulatory physiology (01.05.2022)
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Journal Article
Validation of GCN5L1/BLOC1S1/BLOS1 antibodies using knockout cells and tissue
Bugga, Paramesha, Stoner, Michael W, Manning, Janet R, Mushala, Bellina A S, Bhattarai, Nisha, Sharifi-Sanjani, Maryam, Webster, Bradley R, Thapa, Dharendra, Scott, Iain
Published in Biochemical journal (22.05.2024)
Published in Biochemical journal (22.05.2024)
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Journal Article
Adropin regulates pyruvate dehydrogenase in cardiac cells via a novel GPCR-MAPK-PDK4 signaling pathway
Thapa, Dharendra, Stoner, Michael W., Zhang, Manling, Xie, Bingxian, Manning, Janet R., Guimaraes, Danielle, Shiva, Sruti, Jurczak, Michael J., Scott, Iain
Published in Redox biology (01.09.2018)
Published in Redox biology (01.09.2018)
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Journal Article
Myocardial brain-derived neurotrophic factor regulates cardiac bioenergetics through the transcription factor Yin Yang 1
Yang, Xue, Zhang, Manling, Xie, Bingxian, Peng, Zishan, Manning, Janet R, Zimmerman, Raymond, Wang, Qin, Wei, An-Chi, Khalifa, Moustafa, Reynolds, Michael, Jin, Jenny, Om, Matthew, Zhu, Guangshuo, Bedja, Djahida, Jiang, Hong, Jurczak, Michael, Shiva, Sruti, Scott, Iain, O'Rourke, Brian, Kass, David A, Paolocci, Nazareno, Feng, Ning
Published in Cardiovascular research (31.03.2023)
Published in Cardiovascular research (31.03.2023)
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Journal Article
The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA
Thapa, Dharendra, Wu, Kaiyuan, Stoner, Michael W., Xie, Bingxian, Zhang, Manling, Manning, Janet R., Lu, Zhongping, Li, Jian H., Chen, Yong, Gucek, Marjan, Playford, Martin P., Mehta, Nehal N., Harmon, Daniel, O’Doherty, Robert M., Jurczak, Michael J., Sack, Michael N., Scott, Iain
Published in The Journal of biological chemistry (16.11.2018)
Published in The Journal of biological chemistry (16.11.2018)
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Journal Article
Loss of GCN5L1 in cardiac cells disrupts glucose metabolism and promotes cell death via reduced Akt/mTORC2 signaling
Manning, Janet R, Thapa, Dharendra, Zhang, Manling, Stoner, Michael W, Traba, Javier, Corey, Catherine, Shiva, Sruti, Sack, Michael N, Scott, Iain
Published in Biochemical journal (19.06.2019)
Published in Biochemical journal (19.06.2019)
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Journal Article
Cardiomyocyte-specific deletion of GCN5L1 in mice restricts mitochondrial protein hyperacetylation in response to a high fat diet
Thapa, Dharendra, Manning, Janet R., Stoner, Michael W., Zhang, Manling, Xie, Bingxian, Scott, Iain
Published in Scientific reports (30.06.2020)
Published in Scientific reports (30.06.2020)
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Journal Article
Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome
Peoples, Jessica N, Ghazal, Nasab, Duong, Duc M, Hardin, Katherine R, Manning, Janet R, Seyfried, Nicholas T, Faundez, Victor, Kwong, Jennifer Q
Published in American Journal of Physiology: Cell Physiology (01.09.2021)
Published in American Journal of Physiology: Cell Physiology (01.09.2021)
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Journal Article
Adropin treatment restores cardiac glucose oxidation in pre-diabetic obese mice
Thapa, Dharendra, Xie, Bingxian, Zhang, Manling, Stoner, Michael W., Manning, Janet R., Huckestein, Brydie R., Edmunds, Lia R., Mullett, Steven J., McTiernan, Charles F., Wendell, Stacy G., Jurczak, Michael J., Scott, Iain
Published in Journal of molecular and cellular cardiology (01.04.2019)
Published in Journal of molecular and cellular cardiology (01.04.2019)
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Journal Article
G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction
Mushala, Bellina A. S., Xie, Bingxian, Sipula, Ian J., Stoner, Michael W., Thapa, Dharendra, Manning, Janet R., Bugga, Paramesha, Vandevender, Amber M., Jurczak, Michael J., Scott, Iain
Published in Scientific reports (15.04.2023)
Published in Scientific reports (15.04.2023)
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Journal Article
Cardiac-specific deletion of GCN5L1 restricts recovery from ischemia-reperfusion injury
Manning, Janet R., Thapa, Dharendra, Zhang, Manling, Stoner, Michael W., Traba, Javier, McTiernan, Charles F., Corey, Catherine, Shiva, Sruti, Sack, Michael N., Scott, Iain
Published in Journal of molecular and cellular cardiology (01.04.2019)
Published in Journal of molecular and cellular cardiology (01.04.2019)
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Journal Article
Phosphoproteomic analysis identifies phospho-Threonine-17 site of phospholamban important in low molecular weight isoform of fibroblast growth factor 2-induced protection against post-ischemic cardiac dysfunction
Manning, Janet R., Wijeratne, Aruna B., Oloizia, Brian B., Zhang, Yu, Greis, Kenneth D., Schultz, Jo El J.
Published in Journal of molecular and cellular cardiology (01.11.2020)
Published in Journal of molecular and cellular cardiology (01.11.2020)
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Journal Article
Adropin reduces blood glucose levels in mice by limiting hepatic glucose production
Thapa, Dharendra, Xie, Bingxian, Manning, Janet R., Zhang, Manling, Stoner, Michael W., Huckestein, Brydie R., Edmunds, Lia R., Zhang, Xueyang, Dedousis, Nikolaos L., O'Doherty, Robert M., Jurczak, Michael J., Scott, Iain
Published in Physiological reports (01.04.2019)
Published in Physiological reports (01.04.2019)
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Journal Article
Loss of Rad-GTPase produces a novel adaptive cardiac phenotype resistant to systolic decline with aging
Manning, Janet R, Withers, Catherine N, Levitan, Bryana, Smith, Jeffrey D, Andres, Douglas A, Satin, Jonathan
Published in American journal of physiology. Heart and circulatory physiology (01.10.2015)
Published in American journal of physiology. Heart and circulatory physiology (01.10.2015)
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Journal Article
GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate oxidation
Thapa, Dharendra, Bugga, Paramesha, Mushala, Bellina A. S., Manning, Janet R., Stoner, Michael W., McMahon, Brenda, Zeng, Xuemei, Cantrell, Pamela S., Yates, Nathan, Xie, Bingxian, Edmunds, Lia R., Jurczak, Michael J., Scott, Iain
Published in Physiological reports (01.08.2022)
Published in Physiological reports (01.08.2022)
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Journal Article
Calreticulin expression in human cardiac myocytes induces ER stress‐associated apoptosis
Stoner, Michael W., McTiernan, Charles F., Scott, Iain, Manning, Janet R.
Published in Physiological reports (01.04.2020)
Published in Physiological reports (01.04.2020)
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Journal Article
Reduced acetylation of TFAM promotes bioenergetic dysfunction in the failing heart
Zhang, Manling, Feng, Ning, Peng, Zishan, Thapa, Dharendra, Stoner, Michael W., Manning, Janet R., McTiernan, Charles F., Yang, Xue, Jurczak, Michael J., Guimaraes, Danielle, Rao, Krithika, Shiva, Sruti, Kaufman, Brett A., Sack, Michael N., Scott, Iain
Published in iScience (16.06.2023)
Published in iScience (16.06.2023)
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Journal Article
Diet-induced obese mice are resistant to improvements in cardiac function resulting from short-term adropin treatment
Thapa, Dharendra, Xie, Bingxian, Mushala, Bellina A.S., Zhang, Manling, Manning, Janet R., Bugga, Paramesha, Stoner, Michael W., Jurczak, Michael J., Scott, Iain
Published in Current research in physiology (01.01.2022)
Published in Current research in physiology (01.01.2022)
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