NEK8 Links the ATR-Regulated Replication Stress Response and S Phase CDK Activity to Renal Ciliopathies
Choi, Hyo Jei Claudia, Lin, Jia-Ren, Vannier, Jean-Baptiste, Slaats, Gisela G., Kile, Andrew C., Paulsen, Renee D., Manning, Danielle K., Beier, David R., Giles, Rachel H., Boulton, Simon J., Cimprich, Karlene A.
Published in Molecular cell (22.08.2013)
Published in Molecular cell (22.08.2013)
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Journal Article
Nek8 Regulates the Expression and Localization of Polycystin-1 and Polycystin-2
SOHARA, Eisei, YING LUO, JINGJING ZHANG, MANNING, Danielle K, BEIER, David R, JING ZHOU
Published in Journal of the American Society of Nephrology (01.03.2008)
Published in Journal of the American Society of Nephrology (01.03.2008)
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An integrated somatic and germline approach to aid interpretation of germline variants of uncertain significance in cancer susceptibility genes
Schwartz, Alison, Manning, Danielle K., Koeller, Diane R., Chittenden, Anu, Isidro, Raymond A., Hayes, Connor P., Abraamyan, Feruza, Manam, Monica Devi, Dwan, Meaghan, Barletta, Justine A., Sholl, Lynette M., Yurgelun, Matthew B., Rana, Huma Q., Garber, Judy E., Ghazani, Arezou A.
Published in Frontiers in oncology (25.08.2022)
Published in Frontiers in oncology (25.08.2022)
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Journal Article
ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning
Czarnecki, Peter G, Gabriel, George C, Manning, Danielle K, Sergeev, Mikhail, Lemke, Kristi, Klena, Nikolai T, Liu, Xiaoqin, Chen, Yu, Li, You, San Agustin, Jovenal T, Garnaas, Maija K, Francis, Richard J, Tobita, Kimimasa, Goessling, Wolfram, Pazour, Gregory J, Lo, Cecilia W, Beier, David R, Shah, Jagesh V
Published in Nature communications (20.01.2015)
Published in Nature communications (20.01.2015)
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Journal Article
Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary cilia
Shiba, Dai, Manning, Danielle K., Koga, Hisashi, Beier, David R., Yokoyama, Takahiko
Published in Cytoskeleton (Hoboken, N.J.) (01.02.2010)
Published in Cytoskeleton (Hoboken, N.J.) (01.02.2010)
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Journal Article
Development and evaluation of INT2GRATE: a platform for comprehensive assessment of the role of germline variants informed by tumor signature profile in Lynch syndrome
Isidro, Raymond A., Chittenden, Anu, Walker, McKenzie, Schwartz, Alison, Koeller, Diane R., Hayes, Connor P., Unal, Busra, Manam, Monica Devi, Buehler, Ryan M., Manning, Danielle K., Sholl, Lynette M., Redston, Mark S., Yurgelun, Matthew B., Rana, Huma Q., Garber, Judy E., Ghazani, Arezou A.
Published in Frontiers in oncology (24.01.2024)
Published in Frontiers in oncology (24.01.2024)
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Journal Article
Loss of the Ciliary Kinase Nek8 Causes Left-Right Asymmetry Defects
MANNING, Danielle K, SERGEEV, Mikhail, HEESBEEN, Roy G. Van, WONG, Michael D, OH, Jin-Hee, YAN LIU, MARK HENKELMAN, R, DRUMMOND, Lain, SHAH, Jagesh V, BEIER, David R
Published in Journal of the American Society of Nephrology (01.01.2013)
Published in Journal of the American Society of Nephrology (01.01.2013)
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Journal Article
Advancing Precision Oncology in Hereditary Paraganglioma-Pheochromocytoma Syndromes: Integrated Interpretation and Data Sharing of the Germline and Tumor Genomes
Rana, Huma Q, Koeller, Diane R, Walker, McKenzie, Unal, Busra, Levine, Alison Schwartz, Chittenden, Anu, Isidro, Raymond A, Hayes, Connor P, Manam, Monica D, Buehler, Ryan M, Manning, Danielle K, Barletta, Justine A, Hornick, Jason L, Garber, Judy E, Ghazani, Arezou A, Int Grate Oncology Consortium
Published in Cancers (26.02.2024)
Published in Cancers (26.02.2024)
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Journal Article
Assessment of genomic alterations in non-syndromic von Hippel-Lindau: Insight from integrating somatic and germline next generation sequencing genomic data
Manning, Danielle K., Shivdasani, Priyanka, Koeller, Diane R., Schwartz, Alison, Rana, Huma Q., Garber, Judy E., Lindeman, Neal I., Ghazani, Arezou A.
Published in Data in brief (01.12.2021)
Published in Data in brief (01.12.2021)
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Journal Article
An optimized protocol for evaluating pathogenicity of VHL germline variants in patients suspected with von Hippel-Lindau syndrome: Using somatic genome to inform the role of germline variants
Koeller, Diane R., Manning, Danielle K., Schwartz, Alison, Chittenden, Anu, Hayes, Connor P., Abraamyan, Feruza, Rana, Huma Q., Lindeman, Neal I., Garber, Judy E., Ghazani, Arezou A.
Published in MethodsX (01.01.2022)
Published in MethodsX (01.01.2022)
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Journal Article
Deriving tumor purity from cancer next generation sequencing data: applications for quantitative ERBB2 (HER2) copy number analysis and germline inference of BRCA1 and BRCA2 mutations
Siegmund, Stephanie E., Manning, Danielle K., Davineni, Phani K., Dong, Fei
Published in Modern pathology (01.10.2022)
Published in Modern pathology (01.10.2022)
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Journal Article
Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse
Moran, Jennifer L, Bolton, Andrew D, Tran, Pamela V, Brown, Alison, Dwyer, Noelle D, Manning, Danielle K, Bjork, Bryan C, Li, Cheng, Montgomery, Kate, Siepka, Sandra M, Vitaterna, Martha Hotz, Takahashi, Joseph S, Wiltshire, Tim, Kwiatkowski, David J, Kucherlapati, Raju, Beier, David R
Published in Genome Research (01.03.2006)
Published in Genome Research (01.03.2006)
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A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype
Dwyer, Noelle D, Manning, Danielle K, Moran, Jennifer L, Mudbhary, Raksha, Fleming, Michael S, Favero, Carlita B, Vock, Vita M, O'Leary, Dennis D M, Walsh, Christopher A, Beier, David R
Published in Neural development (07.01.2011)
Published in Neural development (07.01.2011)
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Journal Article
Contamination Assessment for Cancer Next-Generation Sequencing
Li, Yvonne Y, Schmidt, Ryan J, Manning, Danielle K, Jia, Yonghui, Dong, Fei
Published in Archives of pathology & laboratory medicine (1976) (02.01.2022)
Published in Archives of pathology & laboratory medicine (1976) (02.01.2022)
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Targeted Informatics for Optimal Detection, Characterization, and Quantification of FLT3 Internal Tandem Duplications Across Multiple Next-Generation Sequencing Platforms
Tsai, Harrison K., Brackett, Diane G., Szeto, David, Frazier, Ryan, MacLeay, Allison, Davineni, Phani, Manning, Danielle K., Garcia, Elizabeth, Lindeman, Neal I., Le, Long P., Lennerz, Jochen K., Gibson, Christopher J., Lindsley, R. Coleman, Kim, Annette S., Nardi, Valentina
Published in The Journal of molecular diagnostics : JMD (01.09.2020)
Published in The Journal of molecular diagnostics : JMD (01.09.2020)
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Validation of targeted next-generation sequencing of cell-free DNA from archival cerebrospinal fluid specimens for the detection of somatic variants in cancer involving the leptomeninges: Cytopathologic and radiographic correlation
Neil, Alexander J, Chukwueke, Ugonma N, Hoover, Nicholas, Marris, Sean R N, Rojas-Rudilla, Vanesa, Manning, Danielle K, Mito, Jeffrey K, Cibas, Edmund S, Sholl, Lynette M
Published in Cancer cytopathology (01.04.2024)
Published in Cancer cytopathology (01.04.2024)
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Journal Article
Pathogenicity of VHL variants in families with non-syndromic von Hippel-Lindau phenotypes: An integrated evaluation of germline and somatic genomic results
Rana, Huma Q., Koeller, Diane R., Schwartz, Alison, Manning, Danielle K., Schneider, Katherine A., Krajewski, Katherine M., Choueiri, Toni K., Lindeman, Neal I., Garber, Judy E., Ghazani, Arezou A.
Published in European journal of medical genetics (01.12.2021)
Published in European journal of medical genetics (01.12.2021)
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Journal Article
Lethal Skeletal Dysplasia in Mice and Humans Lacking the Golgin GMAP-210
Smits, Patrick, Bolton, Andrew D, Funari, Vincent, Hong, Minh, Boyden, Eric D, Lu, Lei, Manning, Danielle K, Dwyer, Noelle D, Moran, Jennifer L, Prysak, Mary, Merriman, Barry, Nelson, Stanley F, Bonafé, Luisa, Superti-Furga, Andrea, Ikegawa, Shiro, Krakow, Deborah, Cohn, Daniel H, Kirchhausen, Tom, Warman, Matthew L, Beier, David R
Published in The New England journal of medicine (21.01.2010)
Published in The New England journal of medicine (21.01.2010)
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ViroPanel: Hybrid Capture and Massively Parallel Sequencing for Simultaneous Detection and Profiling of Oncogenic Virus Infection and Tumor Genome
Slevin, Michael K, Wollison, Bruce M, Powers, Winslow, Burns, Robert T, Patel, Neil, Ducar, Matthew D, Starrett, Gabriel J, Garcia, Elizabeth P, Manning, Danielle K, Cheng, Jingwei, Hanna, Glenn J, Kaye, Kenneth M, Van Hummelen, Paul, Nag, Anwesha, Thorner, Aaron R, DeCaprio, James A, MacConaill, Laura E
Published in The Journal of molecular diagnostics : JMD (01.04.2020)
Published in The Journal of molecular diagnostics : JMD (01.04.2020)
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