Identification and Structure–Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors
Ferreira de Freitas, Renato, Harding, Rachel J, Franzoni, Ivan, Ravichandran, Mani, Mann, Mandeep K, Ouyang, Hui, Lautens, Mark, Santhakumar, Vijayaratnam, Arrowsmith, Cheryl H, Schapira, Matthieu
Published in Journal of medicinal chemistry (24.05.2018)
Published in Journal of medicinal chemistry (24.05.2018)
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Journal Article
Combinatorial Anticancer Drug Screen Identifies Off-Target Effects of Epigenetic Chemical Probes
Barghout, Samir H., Mann, Mandeep K., Aman, Ahmed, Yu, Yifan, Alteen, Matthew G., Schimmer, Aaron D., Schapira, Matthieu, Arrowsmith, Cheryl H., Barsyte-Lovejoy, Dalia
Published in ACS chemical biology (21.10.2022)
Published in ACS chemical biology (21.10.2022)
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Journal Article
Structure–Activity Relationship of USP5 Inhibitors
Mann, Mandeep K, Zepeda-Velázquez, Carlos A, González-Álvarez, Héctor, Dong, Aiping, Kiyota, Taira, Aman, Ahmed M, Loppnau, Peter, Li, Yanjun, Wilson, Brian, Arrowsmith, Cheryl H, Al-Awar, Rima, Harding, Rachel J, Schapira, Matthieu
Published in Journal of medicinal chemistry (28.10.2021)
Published in Journal of medicinal chemistry (28.10.2021)
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Journal Article
Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain
Mann, Mandeep K, Franzoni, Ivan, de Freitas, Renato Ferreira, Tempel, Wolfram, Houliston, Scott, Smith, Leanna, Vedadi, Masoud, Arrowsmith, Cheryl H, Harding, Rachel J, Schapira, Matthieu
Published in Journal of medicinal chemistry (27.11.2019)
Published in Journal of medicinal chemistry (27.11.2019)
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Journal Article
Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6
Harding, Rachel J., Franzoni, Ivan, Mann, Mandeep K., Szewczyk, Magdalena M., Mirabi, Bijan, Ferreira de Freitas, Renato, Owens, Dominic D. G., Ackloo, Suzanne, Scheremetjew, Alexej, Juarez-Ornelas, Kevin A., Sanichar, Randy, Baker, Rachel J., Dank, Christian, Brown, Peter J., Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Schapira, Matthieu, Lautens, Mark, Arrowsmith, Cheryl H.
Published in Journal of medicinal chemistry (10.08.2023)
Published in Journal of medicinal chemistry (10.08.2023)
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Journal Article
Correction to "Structure-Activity Relationship of USP5 Inhibitors"
Mann, Mandeep K, Zepeda-Velázquez, Carlos A, González-Álvarez, Héctor, Dong, Aiping, Kiyota, Taira, Aman, Ahmed M, Loppnau, Peter, Li, Yanjun, Wilson, Brian, Arrowsmith, Cheryl H, Al-Awar, Rima, Harding, Rachel J, Schapira, Matthieu
Published in Journal of medicinal chemistry (13.01.2022)
Published in Journal of medicinal chemistry (13.01.2022)
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Journal Article
Small Molecule Screen Identifies Non-catalytic USP3 Chemical Handle
Mann, Mandeep K., Wolf, Esther, Silva, Madhushika, Kwak, Haejin Angela, Wilson, Brian, Bolotokova, Albina, Wilson, Derek J., Harding, Rachel J., Schapira, Matthieu
Published in ACS omega (09.01.2024)
Published in ACS omega (09.01.2024)
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Journal Article
Systemic administration of monosodium glutamate elevates intramuscular glutamate levels and sensitizes rat masseter muscle afferent fibers
Cairns, Brian E., Dong, Xudong, Mann, Mandeep K., Svensson, Peter, Sessle, Barry J., Arendt-Nielsen, Lars, McErlane, Keith M.
Published in Pain (Amsterdam) (01.11.2007)
Published in Pain (Amsterdam) (01.11.2007)
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Journal Article
Diclofenac exerts local anesthetic-like actions on rat masseter muscle afferent fibers
Cairns, Brian E, Mann, Mandeep K, Mok, Elisa, Dong, Xu-Dong, Svensson, Peter
Published in Brain research (15.02.2008)
Published in Brain research (15.02.2008)
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Journal Article
Same‐day discharge in selected patients undergoing atrial fibrillation ablation
Bartoletti, Stefano, Mann, Mandeep, Gupta, Akanksha, Khan, Abdul Muhaymin, Sahni, Ankita, El‐Kadri, Moutaz, Modi, Simon, Waktare, Johan, Mahida, Saagar, Hall, Mark, Snowdon, Richard, Todd, Derick, Gupta, Dhiraj
Published in Pacing and clinical electrophysiology (01.11.2019)
Published in Pacing and clinical electrophysiology (01.11.2019)
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Journal Article
27 Has the time come for offering day-case atrial fibrillation ablation? patient and procedural characteristics indicative of early uptake
Bartoletti, Stefano, Mann, Mandeep, Gupta, Akanksha, Khan, Abdul, Sahni, Ankita, El-Kadri, Moutaz, Hobbs, Julian, Modi, Simon, Waktare, Johan, Mahida, Saagar, Hall, Mark, Snowdon, Richard, Todd, Derick, Gupta, Dhiraj
Published in Heart (British Cardiac Society) (01.06.2018)
Published in Heart (British Cardiac Society) (01.06.2018)
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Journal Article
Sex-related differences in NMDA-evoked rat masseter muscle afferent discharge result from estrogen-mediated modulation of peripheral NMDA receptor activity
Dong, X.-D, Mann, M.K, Kumar, U, Svensson, P, Arendt-Nielsen, L, Hu, J.W, Sessle, B.J, Cairns, B.E
Published in Neuroscience (11.05.2007)
Published in Neuroscience (11.05.2007)
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Journal Article
Small molecule screen identifies non-catalytic USP3 chemical handle
Mann, Mandeep K, Mirabi, Bijan, Lautens, Mark, Harding, Rachel J, Schapira, Matthieu
Published in bioRxiv (01.03.2023)
Published in bioRxiv (01.03.2023)
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Paper
Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6
Harding, Rachel J, Franzoni, Ivan, Mann, Mandeep K, Szewczyk, Magdalena, Mirabi, Bijan, Owens, Dominic Dg, Ackloo, Suzanne, Scheremetjew, Alexej, Juarez-Ornelas, Kevin A, Sanichar, Randy, Baker, Rachel J, Dank, Christian, Brown, Peter J, Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Schapira, Matthieu, Lautens, Mark, Arrowsmith, Cheryl H
Published in bioRxiv (22.02.2023)
Published in bioRxiv (22.02.2023)
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Paper