Smurf2 regulates stability and the autophagic–lysosomal turnover of lamin A and its disease‐associated form progerin
Borroni, Aurora Paola, Emanuelli, Andrea, Shah, Pooja Anil, Ilić, Nataša, Apel‐Sarid, Liat, Paolini, Biagio, Manikoth Ayyathan, Dhanoop, Koganti, Praveen, Levy‐Cohen, Gal, Blank, Michael
Published in Aging cell (01.04.2018)
Published in Aging cell (01.04.2018)
Get full text
Journal Article
Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer
Emanuelli, Andrea, Manikoth Ayyathan, Dhanoop, Koganti, Praveen, Shah, Pooja Anil, Apel-Sarid, Liat, Paolini, Biagio, Detroja, Rajesh, Frenkel-Morgenstern, Milana, Blank, Michael
Published in Cancers (18.04.2019)
Published in Cancers (18.04.2019)
Get full text
Journal Article
Induction of apoptosis by apocarotenoids in B16 melanoma cells through ROS-mediated mitochondrial-dependent pathway
Anantharaman, Amrita, Hemachandran, Hridya, Mohan, Sankari, Manikoth Ayyathan, Dhanoop, D, Thirumal Kumar, C, George Priya Doss, Siva, Ramamoorthy
Published in Journal of functional foods (01.01.2016)
Published in Journal of functional foods (01.01.2016)
Get full text
Journal Article
The E3 ubiquitin ligase SMURF2 stabilizes RNA editase ADAR1p110 and promotes its adenosine-to-inosine (A-to-I) editing function
Koganti, Praveen, Kadali, Venkata Narasimha, Manikoth Ayyathan, Dhanoop, Emanuelli, Andrea, Paolini, Biagio, Levy-Cohen, Gal, Blank, Michael
Published in Cellular and molecular life sciences : CMLS (01.05.2022)
Published in Cellular and molecular life sciences : CMLS (01.05.2022)
Get full text
Journal Article
SMURF2 prevents detrimental changes to chromatin, protecting human dermal fibroblasts from chromosomal instability and tumorigenesis
Manikoth Ayyathan, Dhanoop, Koganti, Praveen, Marcu-Malina, Victoria, Litmanovitch, Talia, Trakhtenbrot, Luba, Emanuelli, Andrea, Apel-Sarid, Liat, Blank, Michael
Published in Oncogene (16.04.2020)
Published in Oncogene (16.04.2020)
Get full text
Journal Article
Generation of SMURF2 knockout human cells using the CRISPR/Cas9 system
Manikoth Ayyathan, Dhanoop, Ilić, Nataša, Gil-Henn, Hava, Blank, Michael
Published in Analytical biochemistry (15.08.2017)
Published in Analytical biochemistry (15.08.2017)
Get full text
Journal Article
Smurf2-Mediated Stabilization of DNA Topoisomerase IIα Controls Genomic Integrity
Emanuelli, Andrea, Borroni, Aurora P, Apel-Sarid, Liat, Shah, Pooja A, Ayyathan, Dhanoop Manikoth, Koganti, Praveen, Levy-Cohen, Gal, Blank, Michael
Published in Cancer research (Chicago, Ill.) (15.08.2017)
Published in Cancer research (Chicago, Ill.) (15.08.2017)
Get full text
Journal Article
Development and characterisation of SMURF2-targeting modifiers
Manikoth Ayyathan, Dhanoop, Levy-Cohen, Gal, Shubely, Moran, Boutros-Suleiman, Sandy, Lepechkin-Zilbermintz, Veronica, Shokhen, Michael, Albeck, Amnon, Gruzman, Arie, Blank, Michael
Published in Journal of enzyme inhibition and medicinal chemistry (2021)
Published in Journal of enzyme inhibition and medicinal chemistry (2021)
Get full text
Journal Article
Neuroprotective effect of Tagara, an Ayurvedic drug against methyl mercury induced oxidative stress using rat brain mitochondrial fractions
Ayyathan, Dhanoop Manikoth, Chandrasekaran, Rajasekaran, Thiagarajan, Kalaivani
Published in BMC complementary and alternative medicine (12.08.2015)
Published in BMC complementary and alternative medicine (12.08.2015)
Get full text
Journal Article
Metformin Treatment Abrogates the Competitive Advantage of Dnmt3a R878H HSPCs By Enhancing DNA Methylation Activity
Hosseini, Mohsen, Cathelin, Severine, Liu, Alex, Yang, Yitong, Subedi, Amit, Manikoth Ayyathan, Dhanoop, Pai, Shraddha, Chan, Steven M.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
Get full text
Journal Article
Targeting STAT5 Signaling Overcomes Resistance to IDH Inhibitors in Acute Myeloid Leukemia through Suppression of Stemness
Liu, Alex C H, Cathelin, Severine, Yang, Yitong, Dai, David L, Ayyathan, Dhanoop Manikoth, Hosseini, Mohsen, Minden, Mark D, Tierens, Anne, Chan, Steven M
Published in Cancer research (Chicago, Ill.) (02.12.2022)
Published in Cancer research (Chicago, Ill.) (02.12.2022)
Get full text
Journal Article
Neuroprotective effect of Brahmi, an ayurvedic drug against oxidative stress induced by methyl mercury toxicity in rat brain mitochondrial-enriched fractions
Ayyathan, Dhanoop Manikoth, Chandrasekaran, Rajasekaran, Thiagarajan, Kalaivani
Published in Natural product research (03.06.2015)
Published in Natural product research (03.06.2015)
Get full text
Journal Article
Amelioration of methylmercury induced neural damage by essential oil of Selinum vaginatum (Edgew) C. B. Clarke
Thiagarajan, Kalaivani, Gamit, Naisarg, Mandal, Saurabh, Ayyathan, Dhanoop Manikoth, Chandrasekaran, Rajasekaran
Published in Pakistan journal of pharmaceutical sciences (01.03.2018)
Get full text
Published in Pakistan journal of pharmaceutical sciences (01.03.2018)
Journal Article
Amelioration of methylmercury induced neural damage by essential oil of Selinum vaginatum C.B. Clarke
Thiagarajan, Kalaivani, Gamit, Naisarg, Mandal, Saurabh, Ayyathan, Dhanoop Manikoth, Chandrasekaran, Rajasekaran
Published in Pakistan journal of pharmaceutical sciences (01.03.2018)
Get full text
Published in Pakistan journal of pharmaceutical sciences (01.03.2018)
Journal Article
Metformin reduces the clonal fitness of Dnmt3a R878H hematopoietic stem and progenitor cells by reversing their aberrant metabolic and epigenetic state
Hosseini, Mohsen, Voisin, Veronique, Chegini, Ali, Varesi, Angelica, Cathelin, Severine, Ayyathan, Dhanoop Manikoth, Liu, Alex C H, Yang, Yitong, Wang, Vivian, Maher, Abdula, Grignano, Eric, Reisz, Julie A, D'Alessandro, Angelo, Young, Kira, Wu, Yiyan, Fiumara, Martina, Ferrari, Samuele, Naldini, Luigi, Gaiti, Federico, Pai, Shraddha, Schimmer, Aaron D, Bader, Gary D, Dick, John E, Xie, Stephanie Z, Trowbridge, Jennifer J, Chan, Steven M
Published in Research square (06.02.2024)
Get more information
Published in Research square (06.02.2024)
Journal Article