Structure of Dictyostelium discoideum telomeres. Analysis of possible replication mechanisms
Rodriguez-Centeno, Javier, Manguán-García, Cristina, Perona, Rosario, Sastre, Leandro
Published in PloS one (24.09.2019)
Published in PloS one (24.09.2019)
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GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells
Iarriccio, Laura, Manguán-García, Cristina, Pintado-Berninches, Laura, Mancheño, José Miguel, Molina, Antonio, Perona, Rosario, Sastre, Leandro
Published in PloS one (16.11.2015)
Published in PloS one (16.11.2015)
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Targeted Cargo Delivery in Senescent Cells Using Capped Mesoporous Silica Nanoparticles
Agostini, Alessandro, Mondragón, Laura, Bernardos, Andrea, Martínez-Máñez, Ramón, Marcos, M. Dolores, Sancenón, Félix, Soto, Juan, Costero, Ana, Manguan-García, Cristina, Perona, Rosario, Moreno-Torres, Marta, Aparicio-Sanchis, Rafael, Murguía, José Ramón
Published in Angewandte Chemie (International ed.) (15.10.2012)
Published in Angewandte Chemie (International ed.) (15.10.2012)
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GSE4‐loaded nanoparticles a potential therapy for lung fibrosis that enhances pneumocyte growth, reduces apoptosis and DNA damage
Pintado‐Berninches, Laura, Montes‐Worboys, Ana, Manguan‐García, Cristina, Arias‐Salgado, Elena G., Serrano, Adela, Fernandez‐Varas, Beatriz, Guerrero‐López, Rosa, Iarriccio, Laura, Planas, Lurdes, Guenechea, Guillermo, Egusquiaguirre, Susana P., Hernandez, Rosa M., Igartua, Manoli, Luis Pedraz, Jose, Cortijo, Julio, Sastre, Leandro, Molina‐Molina, Maria, Perona, Rosario
Published in The FASEB journal (01.03.2021)
Published in The FASEB journal (01.03.2021)
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Development of surface modified biodegradable polymeric nanoparticles to deliver GSE24.2 peptide to cells: A promising approach for the treatment of defective telomerase disorders
Egusquiaguirre, Susana P., Manguán-García, Cristina, Pintado-Berninches, Laura, Iarriccio, Laura, Carbajo, Daniel, Albericio, Fernando, Royo, Miriam, Pedraz, José Luís, Hernández, Rosa M., Perona, Rosario, Igartua, Manuela
Published in European journal of pharmaceutics and biopharmaceutics (01.04.2015)
Published in European journal of pharmaceutics and biopharmaceutics (01.04.2015)
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Development and validation of a rapid HPLC method for the quantification of GSE4 peptide in biodegradable PEI–PLGA nanoparticles
Egusquiaguirre, Susana P., Manguán-García, Cristina, Perona, Rosario, Pedraz, José Luís, Hernández, Rosa Maria, Igartua, Manuela
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.12.2014)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.12.2014)
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Human recombinant erythropoietin does not promote cancer growth in presence of functional receptors expressed in cancer cells
Belda-Iniesta, Cristóbal, Perona, Rosario, de Castro Carpeño, Javier, Cejas, Paloma, Casado, Enrique, Manguan-García, Cristina, Ibanez de Caceres, Inmaculada, Sanchez-Perez, Isabel, Bernabeu Andreu, Francisco, Alves Ferreira, Javier, Aguilera, Alfredo, de la Peña, Javier, Perez-Sánchez, Elia, Madero, Rosario, Feliu, Jaime, Sereno, María, González-Barón, Manuel
Published in Cancer biology & therapy (01.10.2007)
Published in Cancer biology & therapy (01.10.2007)
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Pyrazino[1,2- b]isoquinolines: Synthesis and study of their cytostatic and cytotoxic properties
Ortín, Irene, González, Juan Francisco, Cuesta, Elena de la, Manguan-García, Cristina, Perona, Rosario, Avendaño, Carmen
Published in Bioorganic & medicinal chemistry (01.10.2008)
Published in Bioorganic & medicinal chemistry (01.10.2008)
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Clinical mutations in the TERT and TERC genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity
Fernández-Varas, Beatriz, Manguan-García, Cristina, Rodriguez-Centeno, Javier, Mendoza-Lupiáñez, Lucía, Calatayud, Joaquin, Perona, Rosario, Martín-Martínez, Mercedes, Gutierrez-Rodriguez, Marta, Benítez-Buelga, Carlos, Sastre, Leandro
Published in Human molecular genetics (18.04.2024)
Published in Human molecular genetics (18.04.2024)
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Mutations in XLF/NHEJ1/Cernunnos gene results in downregulation of telomerase genes expression and telomere shortening
Carrillo, Jaime, Calvete, Oriol, Pintado-Berninches, Laura, Manguan-García, Cristina, Sevilla Navarro, Julian, Arias-Salgado, Elena G, Sastre, Leandro, Guenechea, Guillermo, López Granados, Eduardo, de Villartay, Jean-Pierre, Revy, Patrick, Benitez, Javier, Perona, Rosario
Published in Human molecular genetics (15.05.2017)
Published in Human molecular genetics (15.05.2017)
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Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1
Carrascoso-Rubio, Carlos, Zittersteijn, Hidde A, Pintado-Berninches, Laura, Fernández-Varas, Beatriz, Lozano, M Luz, Manguan-Garcia, Cristina, Sastre, Leandro, Bueren, Juan A, Perona, Rosario, Guenechea, Guillermo
Published in Stem cell research & therapy (29.01.2021)
Published in Stem cell research & therapy (29.01.2021)
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Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells
Manguan-Garcia, Cristina, Pintado-Berninches, Laura, Carrillo, Jaime, Machado-Pinilla, Rosario, Sastre, Leandro, Pérez-Quilis, Carme, Esmoris, Isabel, Gimeno, Amparo, García-Giménez, Jose Luis, Pallardó, Federico V, Perona, Rosario
Published in PloS one (02.07.2014)
Published in PloS one (02.07.2014)
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Targeted Cargo Delivery in Senescent Cells Using Capped Mesoporous Silica Nanoparticles
Agostini, Alessandro, Mondragón, Laura, Bernardos, Andrea, Martínez-Máñez, Ramón, Marcos, M. Dolores, Sancenón, Félix, Soto, Juan, Costero, Ana, Manguan-García, Cristina, Perona, Rosario, Moreno-Torres, Marta, Aparicio-Sanchis, Rafael, Murguía, José Ramón
Published in Angewandte Chemie (15.10.2012)
Published in Angewandte Chemie (15.10.2012)
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MKP1 repression is required for the chemosensitizing effects of NF-κB and PI3K inhibitors to cisplatin in non-small cell lung cancer
Cortes-Sempere, María, Chattopadhyay, Sharmila, Rovira, Ana, Rodriguez-Fanjul, Vanessa, Belda-Iniesta, Cristobal, Tapia, Marian, Cejas, Paloma, Machado-Pinilla, Rosario, Manguan-García, Cristina, Sánchez-Pérez, Isabel, Nistal, Manuel, Moratilla, Carmen, Castro-Carpeño, Javier de, Gonzalez-Barón, Manuel, Albanell, Joan, Perona, Rosario
Published in Cancer letters (28.12.2009)
Published in Cancer letters (28.12.2009)
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MKP1 repression is required for the chemosensitizing effects of NF-[kappa]B and PI3K inhibitors to cisplatin in non-small cell lung cancer
Cortes-Sempere, María, Chattopadhyay, Sharmila, Rovira, Ana, Rodriguez-Fanjul, van essa, Belda-Iniesta, Cristobal, Tapia, Marian, Cejas, Paloma, Machado-Pinilla, Rosario, Manguan-García, Cristina, Sánchez-Pérez, Isabel, Nistal, Manuel, Moratilla, Carmen, Castro-Carpeño, Javier de, Gonzalez-Barón, Manuel, Albanell, Joan, Perona, Rosario
Published in Cancer letters (28.12.2009)
Published in Cancer letters (28.12.2009)
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Journal Article
GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells
Pintado-Berninches, Laura, Fernandez-Varas, Beatriz, Benitez-Buelga, Carlos, Manguan-Garcia, Cristina, Serrano-Benitez, Almudena, Iarriccio, Laura, Carrillo, Jaime, Guenechea, Guillermo, Egusquiaguirre, Susana P, Pedraz, Jose-Luis, Hernández, Rosa M, Igartua, Manoli, Arias-Salgado, Elena G, Cortés-Ledesma, Felipe, Sastre, Leandro, Perona, Rosario
Published in Cell death and differentiation (01.10.2019)
Published in Cell death and differentiation (01.10.2019)
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Journal Article
Targeted Cargo Delivery in Senescent Cells Using Capped Mesoporous Silica Nanoparticles
Agostini, Alessandro, Mondragón, Laura, Bernardos, Andrea, Martínez‐Máñez, Ramón, Marcos, M. Dolores, Sancenón, Félix, Soto, Juan, Costero, Ana, Manguan‐García, Cristina, Perona, Rosario, Moreno‐Torres, Marta, Aparicio‐Sanchis, Rafael, Murguía, José Ramón
Published in Angewandte Chemie (15.10.2012)
Published in Angewandte Chemie (15.10.2012)
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Journal Article
MKP1 repression is required for the chemosensitizing effects of NF-kappaB and PI3K inhibitors to cisplatin in non-small cell lung cancer
Cortes-Sempere, María, Chattopadhyay, Sharmila, Rovira, Ana, Rodriguez-Fanjul, Vanessa, Belda-Iniesta, Cristobal, Tapia, Marian, Cejas, Paloma, Machado-Pinilla, Rosario, Manguan-García, Cristina, Sánchez-Pérez, Isabel, Nistal, Manuel, Moratilla, Carmen, de Castro-Carpeño, Javier, Gonzalez-Barón, Manuel, Albanell, Joan, Perona, Rosario
Published in Cancer letters (28.12.2009)
Published in Cancer letters (28.12.2009)
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Journal Article
Expression of the Genetic Suppressor Element 24.2
Manguan-Garcia, Cristina, Pintado-Berninches, Laura, Carrillo, Jaime, Machado-Pinilla, Rosario, Sastre, Leandro, Pérez-Quilis, Carme, Esmoris, Isabel, Gimeno, Amparo, García-Giménez, Jose Luis, Pallardó, Federico V, Perona, Rosario
Published in PloS one (02.07.2014)
Published in PloS one (02.07.2014)
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