Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir
Yayla, Hatice G., Peng, Feng, Mangion, Ian K., McLaughlin, Mark, Campeau, Louis-Charles, Davies, Ian W., DiRocco, Daniel A., Knowles, Robert R.
Published in Chemical science (Cambridge) (01.03.2016)
Published in Chemical science (Cambridge) (01.03.2016)
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Journal Article
Mass Activated Droplet Sorting (MADS) Enables High‐Throughput Screening of Enzymatic Reactions at Nanoliter Scale
Holland‐Moritz, Daniel A., Wismer, Michael K., Mann, Benjamin F., Farasat, Iman, Devine, Paul, Guetschow, Erik D., Mangion, Ian, Welch, Christopher J., Moore, Jeffrey C., Sun, Shuwen, Kennedy, Robert T.
Published in Angewandte Chemie International Edition (09.03.2020)
Published in Angewandte Chemie International Edition (09.03.2020)
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Journal Article
The Emergence of Universal Chromatographic Methods in the Research and Development of New Drug Substances
Regalado, Erik L, Haidar Ahmad, Imad A, Bennett, Raffeal, D’Atri, Valentina, Makarov, Alexey A, Humphrey, Guy R, Mangion, Ian, Guillarme, Davy
Published in Accounts of chemical research (16.07.2019)
Published in Accounts of chemical research (16.07.2019)
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Journal Article
Chaotropic Effects in Sub/Supercritical Fluid Chromatography via Ammonium Hydroxide in Water-Rich Modifiers: Enabling Separation of Peptides and Highly Polar Pharmaceuticals at the Preparative Scale
Liu, Jinchu, Makarov, Alexey A, Bennett, Raffeal, Haidar Ahmad, Imad A, DaSilva, Jimmy, Reibarkh, Mikhail, Mangion, Ian, Mann, Benjamin F, Regalado, Erik L
Published in Analytical chemistry (Washington) (05.11.2019)
Published in Analytical chemistry (Washington) (05.11.2019)
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Journal Article
Iridium-Catalyzed X−H Insertions of Sulfoxonium Ylides
Mangion, Ian K, Nwamba, Ikenna K, Shevlin, Michael, Huffman, Mark A
Published in Organic letters (20.08.2009)
Published in Organic letters (20.08.2009)
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Journal Article
A Concise Synthesis of a β-Lactamase Inhibitor
Mangion, Ian K, Ruck, Rebecca T, Rivera, Nelo, Huffman, Mark A, Shevlin, Michael
Published in Organic letters (21.10.2011)
Published in Organic letters (21.10.2011)
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Journal Article
Enantioselective Synthesis of a Dual Orexin Receptor Antagonist
Mangion, Ian K, Sherry, Benjamin D, Yin, Jingjun, Fleitz, Fred J
Published in Organic letters (06.07.2012)
Published in Organic letters (06.07.2012)
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Journal Article
Evaluation of global conformational changes in peptides and proteins following purification by supercritical fluid chromatography
Schiavone, Nicole M., Bennett, Raffeal, Hicks, Michael B., Pirrone, Gregory F., Regalado, Erik L., Mangion, Ian, Makarov, Alexey A.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.03.2019)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.03.2019)
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Journal Article
Bio- and Chemocatalysis for the Synthesis of Late Stage SAR-Enabling Intermediates for ROMK Inhibitors and MK-7145 for the Treatment of Hypertension and Heart Failure
Ruck, Rebecca T, Chen, Qinghao, Rivera, Nelo, Kong, Jongrock, Mangion, Ian K, Tan, Lushi, Fleitz, Fred J
Published in Organic process research & development (19.03.2021)
Published in Organic process research & development (19.03.2021)
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Journal Article
Automated ion exchange chromatography screening combined with in silico multifactorial simulation for efficient method development and purification of biopharmaceutical targets
Losacco, Gioacchino Luca, Hicks, Michael B., DaSilva, Jimmy O., Wang, Heather, Potapenko, Miraslava, Tsay, Fuh-Rong, Ahmad, Imad A. Haidar, Mangion, Ian, Guillarme, Davy, Regalado, Erik L.
Published in Analytical and bioanalytical chemistry (01.05.2022)
Published in Analytical and bioanalytical chemistry (01.05.2022)
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Journal Article
Total Synthesis of Brasoside and Littoralisone
Mangion, Ian K, MacMillan, David W. C
Published in Journal of the American Chemical Society (23.03.2005)
Published in Journal of the American Chemical Society (23.03.2005)
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Journal Article
Total synthesis of diazonamide A
Knowles, Robert R, Carpenter, Joseph, Blakey, Simon B, Kayano, Akio, Mangion, Ian K, Sinz, Christopher J, Macmillan, David W C
Published in Chemical science (Cambridge) (01.01.2011)
Published in Chemical science (Cambridge) (01.01.2011)
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Journal Article
Selective Plate-Based Assay for Trace EDTA Analysis via Boron Trifluoride-methanol Derivatization UHPLC-QqQ-MS/MS Enabling Biologic and Vaccine Processes
Bennett, Raffeal, Cohen, Ryan D, Wang, Heather, Pereira, Tony, Haverick, Mark A, Loughney, John W, Barbacci, Damon C, Pristatsky, Pavlo, Bowman, Amy M, Losacco, Gioacchino Luca, Richardson, Douglas D, Mangion, Ian, Regalado, Erik L
Published in Analytical chemistry (Washington) (25.01.2022)
Published in Analytical chemistry (Washington) (25.01.2022)
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Journal Article
Enantioselective Synthesis of an HCV NS5a Antagonist
Mangion, Ian K., Chen, Cheng-yi, Li, Hongmei, Maligres, Peter, Chen, Yonggang, Christensen, Melodie, Cohen, Ryan, Jeon, Ingyu, Klapars, Artis, Krska, Shane, Nguyen, Hoa, Reamer, Robert A., Sherry, Benjamin D., Zavialov, Ilia
Published in Organic letters (02.05.2014)
Published in Organic letters (02.05.2014)
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Journal Article
Successive remodeling of IgG glycans using a solid-phase enzymatic platform
Hsu, Yen-Pang, Verma, Deeptak, Sun, Shuwen, McGregor, Caroline, Mangion, Ian, Mann, Benjamin F
Published in Communications biology (07.04.2022)
Published in Communications biology (07.04.2022)
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Journal Article
Highly Efficient Synthesis of HIV NNRTI Doravirine
Gauthier, Donald R, Sherry, Benjamin D, Cao, Yang, Journet, Michel, Humphrey, Guy, Itoh, Tetsuji, Mangion, Ian, Tschaen, David M
Published in Organic letters (20.03.2015)
Published in Organic letters (20.03.2015)
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Journal Article