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Wang, Zhi-Hao, Xiang, Jie, Liu, Xia, Yu, Shan Ping, Manfredsson, Fredric P., Sandoval, Ivette M., Wu, Shengxi, Wang, Jian-Zhi, Ye, Keqiang
Published in Cell reports (Cambridge) (16.07.2019)
Published in Cell reports (Cambridge) (16.07.2019)
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Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus
Kang, Seong Su, Liu, Xia, Ahn, Eun Hee, Xiang, Jie, Manfredsson, Fredric P, Yang, Xifei, Luo, Hongbo R, Liles, L Cameron, Weinshenker, David, Ye, Keqiang
Published in The Journal of clinical investigation (01.01.2020)
Published in The Journal of clinical investigation (01.01.2020)
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Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology
Manfredsson, Fredric P., Luk, Kelvin C., Benskey, Matthew J., Gezer, Aysegul, Garcia, Joanna, Kuhn, Nathan C., Sandoval, Ivette M., Patterson, Joseph R., O'Mara, Alana, Yonkers, Reid, Kordower, Jeffrey H.
Published in Neurobiology of disease (01.04.2018)
Published in Neurobiology of disease (01.04.2018)
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Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration
Paumier, Katrina L, Luk, Kelvin C, Manfredsson, Fredric P, Kanaan, Nicholas M, Lipton, Jack W, Collier, Timothy J, Steece-Collier, Kathy, Kemp, Christopher J, Celano, Stephanie, Schulz, Emily, Sandoval, Ivette M, Fleming, Sheila, Dirr, Elliott, Polinski, Nicole K, Trojanowski, John Q, Lee, Virginia M, Sortwell, Caryl E
Published in Neurobiology of disease (01.10.2015)
Published in Neurobiology of disease (01.10.2015)
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C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer’s disease
Wang, Zhi-Hao, Gong, Ke, Liu, Xia, Zhang, Zhentao, Sun, Xiaoou, Wei, Zheng Zachory, Yu, Shan Ping, Manfredsson, Fredric P., Sandoval, Ivette M., Johnson, Peter F., Jia, Jianping, Wang, Jian-Zhi, Ye, Keqiang
Published in Nature communications (03.05.2018)
Published in Nature communications (03.05.2018)
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Nicotine-Mediated Recruitment of GABAergic Neurons to a Dopaminergic Phenotype Attenuates Motor Deficits in an Alpha-Synuclein Parkinson's Model
Lai, Jessica IChi, Porcu, Alessandra, Romoli, Benedetto, Keisler, Maria, Manfredsson, Fredric P, Powell, Susan B, Dulcis, Davide
Published in International journal of molecular sciences (01.02.2023)
Published in International journal of molecular sciences (01.02.2023)
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Characterizing the relationship between L-DOPA-induced-dyskinesia and psychosis-like behaviors in a bilateral rat model of Parkinson's disease
Lipari, Natalie, Centner, Ashley, Glinski, John, Cohen, Sophie, Manfredsson, Fredric P., Bishop, Christopher
Published in Neurobiology of disease (01.01.2023)
Published in Neurobiology of disease (01.01.2023)
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Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer’s Disease
Wang, Zhi-Hao, Liu, Pai, Liu, Xia, Manfredsson, Fredric P., Sandoval, Ivette M., Yu, Shan Ping, Wang, Jian-Zhi, Ye, Keqiang
Published in Molecular cell (07.09.2017)
Published in Molecular cell (07.09.2017)
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Neonatal Nicotine Exposure Primes Midbrain Neurons to a Dopaminergic Phenotype and Increases Adult Drug Consumption
Romoli, Benedetto, Lozada, Adrian F., Sandoval, Ivette M., Manfredsson, Fredric P., Hnasko, Thomas S., Berg, Darwin K., Dulcis, Davide
Published in Biological psychiatry (1969) (01.09.2019)
Published in Biological psychiatry (1969) (01.09.2019)
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Oxytocin receptors in the midbrain dorsal raphe are essential for postpartum maternal social and affective behaviors
Grieb, Zachary A., Ford, Emma G., Yagan, Mahircan, Lau, Billy Y.B., Manfredsson, Fredric P., Krishnan, Keerthi, Lonstein, Joseph S.
Published in Psychoneuroendocrinology (01.09.2021)
Published in Psychoneuroendocrinology (01.09.2021)
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Epigenetic inactivation of the autophagy–lysosomal system in appendix in Parkinson’s disease
Gordevicius, Juozas, Li, Peipei, Marshall, Lee L., Killinger, Bryan A., Lang, Sean, Ensink, Elizabeth, Kuhn, Nathan C., Cui, Wei, Maroof, Nazia, Lauria, Roberta, Rueb, Christina, Siebourg-Polster, Juliane, Maliver, Pierre, Lamp, Jared, Vega, Irving, Manfredsson, Fredric P., Britschgi, Markus, Labrie, Viviane
Published in Nature communications (26.08.2021)
Published in Nature communications (26.08.2021)
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A comparison of AAV-vector production methods for gene therapy and preclinical assessment
Davidsson, Marcus, Negrini, Matilde, Hauser, Swantje, Svanbergsson, Alexander, Lockowandt, Marcus, Tomasello, Giuseppe, Manfredsson, Fredric P., Heuer, Andreas
Published in Scientific reports (09.12.2020)
Published in Scientific reports (09.12.2020)
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Downregulation of striatal CaV1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age
Caulfield, Margaret E., Vander Werp, Molly J., Stancati, Jennifer A., Collier, Timothy J., Sortwell, Caryl E., Sandoval, Ivette M., Manfredsson, Fredric P., Steece-Collier, Kathy
Published in Neurobiology of disease (01.06.2023)
Published in Neurobiology of disease (01.06.2023)
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Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity
Benskey, Matthew J, Sellnow, Rhyomi C, Sandoval, Ivette M, Sortwell, Caryl E, Lipton, Jack W, Manfredsson, Fredric P
Published in Frontiers in molecular neuroscience (13.02.2018)
Published in Frontiers in molecular neuroscience (13.02.2018)
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Morphological and behavioral impact of AAV2/5-mediated overexpression of human wildtype alpha-synuclein in the rat nigrostriatal system
Gombash, Sara E, Manfredsson, Fredric P, Kemp, Christopher J, Kuhn, Nathan C, Fleming, Sheila M, Egan, Ann E, Grant, Laura M, Ciucci, Michelle R, MacKeigan, Jeffrey P, Sortwell, Caryl E
Published in PloS one (27.11.2013)
Published in PloS one (27.11.2013)
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phosphorylation state of Ser-129 in human α-synuclein determines neurodegeneration in a rat model of Parkinson disease
Gorbatyuk, Oleg S, Li, Shoudong, Sullivan, Layla F, Chen, Weijun, Kondrikova, Galina, Manfredsson, Fredric P, Mandel, Ronald J, Muzyczka, Nicholas
Published in Proceedings of the National Academy of Sciences - PNAS (15.01.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (15.01.2008)
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Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease
Sellnow, Rhyomi C, Steece-Collier, Kathy, Altwal, Feras, Sandoval, Ivette M, Kordower, Jeffrey H, Collier, Timothy J, Sortwell, Caryl E, West, Anthony R, Manfredsson, Fredric P
Published in The Journal of neuroscience (29.04.2020)
Published in The Journal of neuroscience (29.04.2020)
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