Perturbation of Hypothalamic MicroRNA Expression Patterns in Male Rats After Metabolic Distress: Impact of Obesity and Conditions of Negative Energy Balance
Sangiao-Alvarellos, Susana, Pena-Bello, Lara, Manfredi-Lozano, María, Tena-Sempere, Manuel, Cordido, Fernando
Published in Endocrinology (Philadelphia) (01.05.2014)
Published in Endocrinology (Philadelphia) (01.05.2014)
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Journal Article
Generation of multi-oocyte follicles in the peripubertal rat ovary: link to the invasive capacity of granulosa cells?
Gaytán, Francisco, M.D., Ph.D, Morales, Concepción, M.D., Ph.D, Manfredi-Lozano, María, B.Sc, Tena-Sempere, Manuel, M.D., Ph.D
Published in Fertility and sterility (01.05.2014)
Published in Fertility and sterility (01.05.2014)
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Journal Article
Kisspeptin Receptor Haplo-insufficiency Causes Premature Ovarian Failure Despite Preserved Gonadotropin Secretion
Gaytan, Francisco, Garcia-Galiano, David, Dorfman, Mauricio D, Manfredi-Lozano, Maria, Castellano, Juan M, Dissen, Gregory A, Ojeda, Sergio R, Tena-Sempere, Manuel
Published in Endocrinology (Philadelphia) (01.08.2014)
Published in Endocrinology (Philadelphia) (01.08.2014)
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Journal Article
Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3
Heras, Violeta, Sangiao-Alvarellos, Susana, Manfredi-Lozano, Maria, Sanchez-Tapia, María J, Ruiz-Pino, Francisco, Roa, Juan, Lara-Chica, Maribel, Morrugares-Carmona, Rosario, Jouy, Nathalie, Abreu, Ana P, Prevot, Vincent, Belsham, Denise, Vazquez, Maria J, Calzado, Marco A, Pinilla, Leonor, Gaytan, Francisco, Latronico, Ana C, Kaiser, Ursula B, Castellano, Juan M, Tena-Sempere, Manuel
Published in PLoS biology (07.11.2019)
Published in PLoS biology (07.11.2019)
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Journal Article
Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity
León, Silvia, Barroso, Alexia, Vázquez, María J., García-Galiano, David, Manfredi-Lozano, María, Ruiz-Pino, Francisco, Heras, Violeta, Romero-Ruiz, Antonio, Roa, Juan, Schutz, Günther, Kirilov, Milen, Gaytan, Francisco, Pinilla, Leonor, Tena-Sempere, Manuel
Published in Scientific reports (12.01.2016)
Published in Scientific reports (12.01.2016)
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Journal Article
Intergenerational Influence of Paternal Obesity on Metabolic and Reproductive Health Parameters of the Offspring: Male-Preferential Impact and Involvement of Kiss1-Mediated Pathways
Sanchez-Garrido, Miguel Angel, Ruiz-Pino, Francisco, Velasco, Inmaculada, Barroso, Alexia, Fernandois, Daniela, Heras, Violeta, Manfredi-Lozano, Maria, Vazquez, Maria Jesus, Castellano, Juan Manuel, Roa, Juan, Pinilla, Leonor, Tena-Sempere, Manuel
Published in Endocrinology (Philadelphia) (01.02.2018)
Published in Endocrinology (Philadelphia) (01.02.2018)
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Journal Article
Physiological Roles of Gonadotropin-Inhibitory Hormone Signaling in the Control of Mammalian Reproductive Axis: Studies in the NPFF1 Receptor Null Mouse
León, Silvia, García-Galiano, David, Ruiz-Pino, Francisco, Barroso, Alexia, Manfredi-Lozano, María, Romero-Ruiz, Antonio, Roa, Juan, Vázquez, María J, Gaytan, Francisco, Blomenrohr, Marion, van Duin, Marcel, Pinilla, Leonor, Tena-Sempere, Manuel
Published in Endocrinology (Philadelphia) (01.08.2014)
Published in Endocrinology (Philadelphia) (01.08.2014)
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Journal Article
Role of neurokinin B in the control of female puberty and its modulation by metabolic status
Navarro, Víctor M, Ruiz-Pino, Francisco, Sánchez-Garrido, Miguel A, García-Galiano, David, Hobbs, Samuel J, Manfredi-Lozano, María, León, Silvia, Sangiao-Alvarellos, Susana, Castellano, Juan M, Clifton, Donald K, Pinilla, Leonor, Steiner, Robert A, Tena-Sempere, Manuel
Published in The Journal of neuroscience (15.02.2012)
Published in The Journal of neuroscience (15.02.2012)
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Journal Article
Obesity-Induced Hypogonadism in the Male: Premature Reproductive Neuroendocrine Senescence and Contribution of Kiss1-Mediated Mechanisms
Sánchez-Garrido, Miguel Angel, Ruiz-Pino, Francisco, Manfredi-Lozano, Maria, Leon, Silvia, Garcia-Galiano, David, Castaño, Justo P, Luque, Raul M, Romero-Ruiz, Antonio, Castellano, Juan M, Diéguez, Carlos, Pinilla, Leonor, Tena-Sempere, Manuel
Published in Endocrinology (Philadelphia) (01.03.2014)
Published in Endocrinology (Philadelphia) (01.03.2014)
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Journal Article
Sex-Biased Physiological Roles of NPFF1R, the Canonical Receptor of RFRP-3, in Food Intake and Metabolic Homeostasis Revealed by its Congenital Ablation in mice
Leon, Silvia, Velasco, Inmaculada, Vázquez, Maria J., Barroso, Alexia, Beiroa, Daniel, Heras, Violeta, Ruiz-Pino, Francisco, Manfredi-Lozano, Maria, Romero-Ruiz, Antonio, Sanchez-Garrido, Miguel A., Dieguez, Carlos, Pinilla, Leonor, Roa, Juan, Nogueiras, Ruben, Tena-Sempere, Manuel
Published in Metabolism, clinical and experimental (01.10.2018)
Published in Metabolism, clinical and experimental (01.10.2018)
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Journal Article
Metabolic and Gonadotropic Impact of Sequential Obesogenic Insults in the Female: Influence of the Loss of Ovarian Secretion
Sánchez-Garrido, Miguel A, Ruiz-Pino, Francisco, Manfredi-Lozano, María, Leon, Silvia, Heras, Violeta, Castellano, Juan M, Castaño, Justo P, Luque, Raúl M, Vázquez, María J, Roa, Juan, Romero-Ruiz, Antonio, Diéguez, Carlos, Pinilla, Leonor, Tena-Sempere, Manuel
Published in Endocrinology (Philadelphia) (01.08.2015)
Published in Endocrinology (Philadelphia) (01.08.2015)
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Journal Article
Distinct Expression Patterns Predict Differential Roles of the miRNA-Binding Proteins, Lin28 and Lin28b, in the Mouse Testis: Studies During Postnatal Development and in a Model of Hypogonadotropic Hypogonadism
Gaytan, Francisco, Sangiao-Alvarellos, Susana, Manfredi-Lozano, María, García-Galiano, David, Ruiz-Pino, Francisco, Romero-Ruiz, Antonio, León, Silvia, Morales, Concepción, Cordido, Fernando, Pinilla, Leonor, Tena-Sempere, Manuel
Published in Endocrinology (Philadelphia) (01.03.2013)
Published in Endocrinology (Philadelphia) (01.03.2013)
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Journal Article
Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty
Manfredi-Lozano, Maria, Roa, Juan, Ruiz-Pino, Francisco, Piet, Richard, Garcia-Galiano, David, Pineda, Rafael, Zamora, Aurora, Leon, Silvia, Sanchez-Garrido, Miguel A, Romero-Ruiz, Antonio, Dieguez, Carlos, Vazquez, Maria Jesus, Herbison, Allan E, Pinilla, Leonor, Tena-Sempere, Manuel
Published in Molecular metabolism (Germany) (01.10.2016)
Published in Molecular metabolism (Germany) (01.10.2016)
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Journal Article
Metabolic regulation of female puberty via hypothalamic AMPK–kisspeptin signaling
Roa, Juan, Barroso, Alexia, Ruiz-Pino, Francisco, Vázquez, Maria Jesus, Seoane-Collazo, Patricia, Martínez-Sanchez, Noelia, García-Galiano, David, Ilhan, Tuncay, Pineda, Rafael, León, Silvia, Manfredi-Lozano, Maria, Heras, Violeta, Poutanen, Matti, Castellano, Juan M., Gaytan, Francisco, Diéguez, Carlos, Pinilla, Leonor, López, Miguel, Tena-Sempere, Manuel
Published in Proceedings of the National Academy of Sciences - PNAS (06.11.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (06.11.2018)
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Journal Article
GnRH replacement rescues cognition in Down syndrome
Manfredi-Lozano, Maria, Leysen, Valerie, Adamo, Michela, Paiva, Isabel, Rovera, Renaud, Pignat, Jean-Michel, Timzoura, Fatima Ezzahra, Candlish, Michael, Eddarkaoui, Sabiha, Malone, Samuel A, Silva, Mauro S B, Trova, Sara, Imbernon, Monica, Decoster, Laurine, Cotellessa, Ludovica, Tena-Sempere, Manuel, Claret, Marc, Paoloni-Giacobino, Ariane, Plassard, Damien, Paccou, Emmanuelle, Vionnet, Nathalie, Acierno, James, Maceski, Aleksandra Maleska, Lutti, Antoine, Pfrieger, Frank, Rasika, S, Santoni, Federico, Boehm, Ulrich, Ciofi, Philippe, Buée, Luc, Haddjeri, Nasser, Boutillier, Anne-Laurence, Kuhle, Jens, Messina, Andrea, Draganski, Bogdan, Giacobini, Paolo, Pitteloud, Nelly, Prevot, Vincent
Published in Science (American Association for the Advancement of Science) (02.09.2022)
Published in Science (American Association for the Advancement of Science) (02.09.2022)
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GnRH neurons recruit astrocytes in infancy to facilitate network integration and sexual maturation
Pellegrino, Giuliana, Martin, Marion, Allet, Cécile, Lhomme, Tori, Geller, Sarah, Franssen, Delphine, Mansuy, Virginie, Manfredi-Lozano, Maria, Coutteau-Robles, Adrian, Delli, Virginia, Rasika, S., Mazur, Danièle, Loyens, Anne, Tena-Sempere, Manuel, Siepmann, Juergen, Pralong, François P., Ciofi, Philippe, Corfas, Gabriel, Parent, Anne-Simone, Ojeda, Sergio R., Sharif, Ariane, Prevot, Vincent
Published in Nature neuroscience (01.12.2021)
Published in Nature neuroscience (01.12.2021)
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Web Resource
Kisspeptin Signaling Is Indispensable for Neurokinin B, but not Glutamate, Stimulation of Gonadotropin Secretion in Mice
García-Galiano, David, van Ingen Schenau, Dorette, Leon, Silvia, Krajnc-Franken, Magda A. M, Manfredi-Lozano, Maria, Romero-Ruiz, Antonio, Navarro, Victor M, Gaytan, Francisco, van Noort, Paula I, Pinilla, Leonor, Blomenröhr, Marion, Tena-Sempere, Manuel
Published in Endocrinology (Philadelphia) (01.01.2012)
Published in Endocrinology (Philadelphia) (01.01.2012)
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Journal Article
GnRH replacement rescues cognition in Down syndrome
Manfredi-Lozano, Maria, Leysen, Valerie, Adamo, Michela, Paiva, Isabel, Rovera, Renaud, Pignat, Jean-Michel, Timzoura, Fatima Ezzahra, Candlish, Michael, Eddarkaoui, Sabiha, Malone, Samuel, Silva, Mauro, Trova, Sara, Imbernon, Monica, Decoster, Laurine, Cotellessa, Ludovica, Tena-Sempere, Manuel, Claret, Marc, Paoloni-Giacobino, Ariane, Plassard, Damien, Paccou, Emmanuelle, Vionnet, Nathalie, Acierno, James, Maceski, Aleksandra Maleska, Lutti, Antoine, Pfrieger, Frank, Rasika, S., Santoni, Federico, Boehm, Ulrich, Ciofi, Philippe, Buée, Luc, Haddjeri, Nasser, Boutillier, Anne-Laurence, Kuhle, Jens, Messina, Andrea, Draganski, Bogdan, Giacobini, Paolo, Pitteloud, Nelly, Prevot, Vincent
Published in Science (American Association for the Advancement of Science) (02.09.2022)
Published in Science (American Association for the Advancement of Science) (02.09.2022)
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Journal Article
cAMP/PKA-Dependent Increases in Ca Sparks, Oscillations and SR Ca Stores in Retinal Arteriolar Myocytes after Exposure to Vasopressin
Jeffries, Owen, McGahon, Mary K, Bankhead, Peter, Lozano, Maria Manfredi, Scholfield, C. Norman, Curtis, Tim M, McGeown, J. Graham
Published in Investigative ophthalmology & visual science (01.03.2010)
Published in Investigative ophthalmology & visual science (01.03.2010)
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Journal Article
PULSATIVE GNRH ADMINISTRATION FOR TREATING COGNITIVE DISORDERS
GIACOBINI, Paolo, MESSINA, Andrea, LEYSEN, Valérie, MANFREDI LOZANO, Maria, PREVOT, Vincent
Year of Publication 30.06.2022
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Year of Publication 30.06.2022
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