Exosome Targeting of Tumor Antigens Expressed by Cancer Vaccines Can Improve Antigen Immunogenicity and Therapeutic Efficacy
ROUNTREE, Ryan B, MANDL, Stefanie J, DELCAYRE, Alain, NACHTWEY, James M, DALPOZZO, Katie, DO, Lisa, LOMBARDO, John R, SCHOONMAKER, Peter L, BRINKMANN, Kay, DIRMEIER, Ulrike, LAUS, Reiner
Published in Cancer research (Chicago, Ill.) (01.08.2011)
Published in Cancer research (Chicago, Ill.) (01.08.2011)
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Journal Article
Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice
Foy, Susan P, Sennino, Barbara, dela Cruz, Tracy, Cote, Joseph J, Gordon, Evan J, Kemp, Felicia, Xavier, Veronica, Franzusoff, Alex, Rountree, Ryan B, Mandl, Stefanie J
Published in PloS one (24.02.2016)
Published in PloS one (24.02.2016)
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Journal Article
Non-viral precision T cell receptor replacement for personalized cell therapy
Foy, Susan P, Jacoby, Kyle, Bota, Daniela A, Hunter, Theresa, Pan, Zheng, Stawiski, Eric, Ma, Yan, Lu, William, Peng, Songming, Wang, Clifford L, Yuen, Benjamin, Dalmas, Olivier, Heeringa, Katharine, Sennino, Barbara, Conroy, Andy, Bethune, Michael T, Mende, Ines, White, William, Kukreja, Monica, Gunturu, Swetha, Humphrey, Emily, Hussaini, Adeel, An, Duo, Litterman, Adam J, Quach, Boi Bryant, Ng, Alphonsus H C, Lu, Yue, Smith, Chad, Campbell, Katie M, Anaya, Daniel, Skrdlant, Lindsey, Huang, Eva Yi-Hsuan, Mendoza, Ventura, Mathur, Jyoti, Dengler, Luke, Purandare, Bhamini, Moot, Robert, Yi, Michael C, Funke, Roel, Sibley, Alison, Stallings-Schmitt, Todd, Oh, David Y, Chmielowski, Bartosz, Abedi, Mehrdad, Yuan, Yuan, Sosman, Jeffrey A, Lee, Sylvia M, Schoenfeld, Adam J, Baltimore, David, Heath, James R, Franzusoff, Alex, Ribas, Antoni, Rao, Arati V, Mandl, Stefanie J
Published in Nature (London) (23.03.2023)
Published in Nature (London) (23.03.2023)
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Journal Article
Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells
Foy, Susan P., Mandl, Stefanie J., dela Cruz, Tracy, Cote, Joseph J., Gordon, Evan J., Trent, Erica, Delcayre, Alain, Breitmeyer, James, Franzusoff, Alex, Rountree, Ryan B.
Published in Cancer Immunology, Immunotherapy (01.05.2016)
Published in Cancer Immunology, Immunotherapy (01.05.2016)
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Journal Article
Immunotherapy with MVA-BN®-HER2 induces HER-2-specific Th1 immunity and alters the intratumoral balance of effector and regulatory T cells
Mandl, Stefanie J., Rountree, Ryan B., Dalpozzo, Katie, Do, Lisa, Lombardo, John R., Schoonmaker, Peter L., Dirmeier, Ulrike, Steigerwald, Robin, Giffon, Thierry, Laus, Reiner, Delcayre, Alain
Published in Cancer Immunology, Immunotherapy (01.01.2012)
Published in Cancer Immunology, Immunotherapy (01.01.2012)
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Journal Article
Elucidating immunologic mechanisms of PROSTVAC cancer immunotherapy
Mandl, Stefanie J, Rountree, Ryan B, Dela Cruz, Tracy B, Foy, Susan P, Cote, Joseph J, Gordon, Evan J, Trent, Erica, Delcayre, Alain, Franzusoff, Alex
Published in Journal for immunotherapy of cancer (14.10.2014)
Published in Journal for immunotherapy of cancer (14.10.2014)
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Journal Article
Breaching Biological Barriers: Protein Translocation Domains as Tools for Molecular Imaging and Therapy
Franc, Benjamin L., Mandl, Stefanie J., Siprashvili, Zurab, Wender, Paul, Contag, Christopher H.
Published in Molecular Imaging (01.10.2003)
Published in Molecular Imaging (01.10.2003)
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Book Review
Journal Article
Multi-modality Imaging Identifies Key Times for Annexin V Imaging as an Early Predictor of Therapeutic Outcome
Mandl, Stefanie J., Mari, Carina, Edinger, Matthias, Negrin, Robert S., Tait, Jonathan F., Contag, Christopher H., Blankenberg, Francis G.
Published in Molecular imaging (01.01.2004)
Published in Molecular imaging (01.01.2004)
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Journal Article
Neoantigen-targeted CD8 + T cell responses with PD-1 blockade therapy
Puig-Saus, Cristina, Sennino, Barbara, Peng, Songming, Wang, Clifford L, Pan, Zheng, Yuen, Benjamin, Purandare, Bhamini, An, Duo, Quach, Boi B, Nguyen, Diana, Xia, Huiming, Jilani, Sameeha, Shao, Kevin, McHugh, Claire, Greer, John, Peabody, Phillip, Nayak, Saparya, Hoover, Jonathan, Said, Sara, Jacoby, Kyle, Dalmas, Olivier, Foy, Susan P, Conroy, Andrew, Yi, Michael C, Shieh, Christine, Lu, William, Heeringa, Katharine, Ma, Yan, Chizari, Shahab, Pilling, Melissa J, Ting, Marc, Tunuguntla, Ramya, Sandoval, Salemiz, Moot, Robert, Hunter, Theresa, Zhao, Sidi, Saco, Justin D, Perez-Garcilazo, Ivan, Medina, Egmidio, Vega-Crespo, Agustin, Baselga-Carretero, Ignacio, Abril-Rodriguez, Gabriel, Cherry, Grace, Wong, Deborah J, Hundal, Jasreet, Chmielowski, Bartosz, Speiser, Daniel E, Bethune, Michael T, Bao, Xiaoyan R, Gros, Alena, Griffith, Obi L, Griffith, Malachi, Heath, James R, Franzusoff, Alex, Mandl, Stefanie J, Ribas, Antoni
Published in Nature (London) (23.03.2023)
Published in Nature (London) (23.03.2023)
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Journal Article
Multi-modality Imaging Identifies Key Times for Annexin V Imaging as an Early Predictor of Therapeutic Outcome
Mandl, Stefanie J., Mari, Carina, Edinger, Matthias, Negrin, Robert S., Tait, Jonathan F., Contag, Christopher H., Blankenberg, Francis G.
Published in Molecular imaging (01.01.2004)
Published in Molecular imaging (01.01.2004)
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Journal Article
Abstract 1526: Single-step precision genome engineering platform enables versatile generation of personalized (neoTCR) adoptive cell therapy T cells with supplementary anti-tumor attributes
Dubreuil, Michael M., Tran, Charles W., Purandare, Bhamini, Lu, William, Byers, James, Mass, Michal, Jacoby, Kyle, Sennino, Barbara, Franzusoff, Alex, Mandl, Stefanie J.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 4783: Highly efficient, non-viral precision genome engineering for the generation of personalized neoepitope-specific adoptive T cell therapies
Jacoby, Kyle, Moot, Robert, Lu, William, Nguyen, Diana, Sennino, Barbara, Conroy, Andrew, Purandare, Bhamini, Litterman, Adam J., Urbinati, Fabrizia, Foy, Susan P., Hunter, Theresa, Tai, Albert, Bethune, Michael T., Peng, Songming, Dalmas, Olivier, Franzusoff, Alex, Mandl, Stefanie J.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 2829: Non-viral precision genome engineering enables personalized adoptive neoTCR T cell therapy for cancer including multiple additional edits that improve the activity of neoTCR T cells by enhancing CD4 T cell antigen sensitivity and conferring resistance to TGFβ
Tran, Charles W., Lee, Kayla, Purandare, Bhamini, Byers, James, Dubreuil, Michael M., Lu, William, Mass, Michal, Jacoby, Kyle, Mandl, Stefanie J., Sennino, Barbara
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Abstract LB-234: Poxvirus-based active immunotherapy synergizes with PD-1 plus LAG-3 immune checkpoint inhibition to enhance antitumor efficacy in preclinical models
Sennino, Barbara, Foy, Susan P., Rountree, Ryan B., dela Cruz, Tracy, Gordon, Evan J., Xavier, Veronica, Kemp, Felicia, Franzusoff, Alex, Breitmeyer, James, Mandl, Stefanie J.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Anti-tumor efficacy and PD-L1 expression in the tumor microenvironment after poxvirus-based active immunotherapy and PD-1 blockade
Mandl, Stefanie J, Foy, Susan P, Sennino, Barbara, dela Cruz, Tracy, Gordon, Evan, Kemp, Felicia, Xavier, Veronica, Rountree, Ryan B, Franzusoff, Alex
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
PROSTVAC, PSA-targeted immunotherapy: New evidence for mechanism of action
Mandl, Stefanie J, Rountree, Ryan B, Owen, Rachel B, dela Cruz, Tracy, Hwang, Olivia, Paranjpe, Gayatri, Enstrom, Amanda, Franzusoff, Alexis J., Goessl, Carsten, Breitmeyer, James Bradley
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Magnitude and quality of tumor-infiltrating T-cell response upon poxvirus-based active immunotherapy alone and in combination with CTLA-4 immune checkpoint inhibition
Foy, Susan P, Mandl, Stefanie J, dela Cruz, Tracy, Cote, Joseph, Gordon, Evan, Trent, Erica, Franzusoff, Alexis J., Rountree, Ryan B
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Antitumor efficacy of poxvirus-based active immunotherapy alone and in combination with subtherapeutic dosing with immune checkpoint inhibitors
Foy, Susan P, Rountree, Ryan B, Cote, Joseph, Gordon, Evan, Trent, Erica, Franzusoff, Alexis J., Breitmeyer, James Bradley, Mandl, Stefanie J
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Abstract A21: Active immunotherapy with PROSTVAC® demonstrates potent antitumor efficacy in a mouse model of prostate cancer
Rountree, Ryan B., Mandl, Stefanie J., Cote, Joseph, Cruz, Tracy dela, Giffon, Thierry, Gordon, Evan, Foy, Susan P., Lombardo, John R., Trent, Erica, Laus, Reiner, Delcayre, Alain
Published in Cancer research (Chicago, Ill.) (01.01.2013)
Published in Cancer research (Chicago, Ill.) (01.01.2013)
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