Tau Blocks Traffic of Organelles, Neurofilaments, and APP Vesicles in Neurons and Enhances Oxidative Stress
Stamer, K., Vogel, R., Thies, E., Mandelkow, E., E.-M. Mandelkow
Published in The Journal of cell biology (18.03.2002)
Published in The Journal of cell biology (18.03.2002)
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Journal Article
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
Mandelkow, E.-M., Stamer, K., Vogel, R., Thies, E., Mandelkow, E.
Published in Neurobiology of aging (01.12.2003)
Published in Neurobiology of aging (01.12.2003)
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Journal Article
Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
Wang, Y.P, Biernat, J, Pickhardt, M, Mandelkow, E, Mandelkow, E.-M
Published in Proceedings of the National Academy of Sciences - PNAS (12.06.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (12.06.2007)
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Journal Article
Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options
Ludolph, A. C., Kassubek, J., Landwehrmeyer, B. G., Mandelkow, E., Mandelkow, E.-M., Burn, D. J., Caparros-Lefebvre, D., Frey, K. A., De Yebenes, J. G., Gasser, T., Heutink, P., Höglinger, G., Jamrozik, Z., Jellinger, K. A., Kazantsev, A., Kretzschmar, H., Lang, A. E., Litvan, I., Lucas, J. J., McGeer, P. L., Melquist, S., Oertel, W., Otto, M., Paviour, D., Reum, T., Saint-Raymond, A., Steele, J. C., Tolnay, M., Tumani, H., Van Swieten, J. C., Vanier, M. T., Vonsattel, J.-P., Wagner, S., Wszolek, Z. K.
Published in European journal of neurology (01.03.2009)
Published in European journal of neurology (01.03.2009)
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Structure, Microtubule Interactions, and Paired Helical Filament Aggregation by Tau Mutants of Frontotemporal Dementias
Barghorn, S, Zheng-Fischhöfer, Q, Ackmann, M, Biernat, J, von Bergen, M, Mandelkow, E.-M, Mandelkow, E
Published in Biochemistry (Easton) (26.09.2000)
Published in Biochemistry (Easton) (26.09.2000)
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Journal Article
Phosphorylation that Detaches Tau Protein from Microtubules (Ser262, Ser214) Also Protects It against Aggregation into Alzheimer Paired Helical Filaments
Schneider, A, Biernat, J, von Bergen, M, Mandelkow, E, Mandelkow, E.-M
Published in Biochemistry (Easton) (23.03.1999)
Published in Biochemistry (Easton) (23.03.1999)
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Overexpression of Tau Protein Inhibits Kinesin-Dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease
Ebneth, A., Godemann, R., Stamer, K., Illenberger, S., Trinczek, B., E.-M. Mandelkow, Mandelkow, E.
Published in The Journal of cell biology (02.11.1998)
Published in The Journal of cell biology (02.11.1998)
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Journal Article
Assembly of τ Protein into Alzheimer Paired Helical Filaments Depends on a Local Sequence Motif (306VQIVYK311) Forming β Structure
von Bergen, M., Friedhoff, P., Biernat, J., Heberle, J., E.-M. Mandelkow, Mandelkow, E.
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2000)
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Journal Article
RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments
Kampers, T., Friedhoff, P., Biernat, J., Mandelkow, E.-M., Mandelkow, E.
Published in FEBS letters (16.12.1996)
Published in FEBS letters (16.12.1996)
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Journal Article
The Crystal Structure of Dimeric Kinesin and Implications for Microtubule-Dependent Motility
Kozielski, F, Sack, S, Marx, A, Thormählen, M, Schönbrunn, E, Biou, V, Thompson, A, Mandelkow, E.-M, Mandelkow, E
Published in Cell (26.12.1997)
Published in Cell (26.12.1997)
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Journal Article
Domains of tau Protein and Interactions with Microtubules
Gustke, N, Trinczek, B, Biernat, J, Mandelkow, E.-M, Mandelkow, E
Published in Biochemistry (Easton) (16.08.1994)
Published in Biochemistry (Easton) (16.08.1994)
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Journal Article
A Nucleated Assembly Mechanism of Alzheimer Paired Helical Filaments
Friedhoff, P., Von Bergen, M., E.-M. Mandelkow, Davies, P., Mandelkow, E.
Published in Proceedings of the National Academy of Sciences - PNAS (22.12.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (22.12.1998)
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Journal Article
Generation of Tau Aggregates and Clearance by Autophagy in an Inducible Cell Model of Tauopathy
Wang, Y., Krüger, U., Mandelkow, E., Mandelkow, E.-M.
Published in Neuro-degenerative diseases (01.01.2010)
Published in Neuro-degenerative diseases (01.01.2010)
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Journal Article
Biochemistry and cell biology of tau protein in neurofibrillary degeneration
Mandelkow, Eva-Maria, Mandelkow, Eckhard
Published in Cold Spring Harbor perspectives in medicine (01.07.2012)
Published in Cold Spring Harbor perspectives in medicine (01.07.2012)
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Journal Article
Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5
Baumann, K., Mandelkow, E.-M., Biernat, J., Piwnica-Worms, H., Mandelkow, E.
Published in FEBS letters (28.12.1993)
Published in FEBS letters (28.12.1993)
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Characterization of a novel transgenic rat carrying human tau with mutation P301L
Korhonen, P, van Groen, T, Thornell, A, Kyrylenko, S, Soininen, M.-L, Ojala, J, Peltomaa, E, Tanila, H, Salminen, A, Mandelkow, E.M, Soininen, H
Published in Neurobiology of aging (01.12.2011)
Published in Neurobiology of aging (01.12.2011)
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