Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria
Parajuli, Narayan Prasad, Emmerich, Andrew, Mandava, Chandra Sekhar, Pavlov, Michael Y., Sanyal, Suparna
Published in Nature communications (17.02.2023)
Published in Nature communications (17.02.2023)
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Journal Article
Repurposing tRNAs for nonsense suppression
Albers, Suki, Beckert, Bertrand, Matthies, Marco C., Mandava, Chandra Sekhar, Schuster, Raphael, Seuring, Carolin, Riedner, Maria, Sanyal, Suparna, Torda, Andrew E., Wilson, Daniel N., Ignatova, Zoya
Published in Nature communications (22.06.2021)
Published in Nature communications (22.06.2021)
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Journal Article
HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions
Zhang, Yanqing, Mandava, Chandra Sekhar, Cao, Wei, Li, Xiaojing, Zhang, Dejiu, Li, Ningning, Zhang, Yixiao, Zhang, Xiaoxiao, Qin, Yan, Mi, Kaixia, Lei, Jianlin, Sanyal, Suparna, Gao, Ning
Published in Nature structural & molecular biology (01.11.2015)
Published in Nature structural & molecular biology (01.11.2015)
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Journal Article
Structural and functional insights into the mode of action of a universally conserved Obg GTPase
Feng, Boya, Mandava, Chandra Sekhar, Guo, Qiang, Wang, Jie, Cao, Wei, Li, Ningning, Zhang, Yixiao, Zhang, Yanqing, Wang, Zhixin, Wu, Jiawei, Sanyal, Suparna, Lei, Jianlin, Gao, Ning
Published in PLoS biology (01.05.2014)
Published in PLoS biology (01.05.2014)
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Journal Article
Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli
Singh, Sudhir, Lahry, Kuldeep, Mandava, Chandra Sekhar, Singh, Jitendra, Shah, Riyaz Ahmad, Sanyal, Suparna, Varshney, Umesh
Published in RNA biology (31.12.2023)
Published in RNA biology (31.12.2023)
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Journal Article
Micrococcin P1 – A bactericidal thiopeptide active against Mycobacterium tuberculosis
Degiacomi, Giulia, Personne, Yoann, Mondésert, Guillaume, Ge, Xueliang, Mandava, Chandra Sekhar, Hartkoorn, Ruben C, Boldrin, Francesca, Goel, Pavitra, Peisker, Kristin, Benjak, Andrej, Barrio, Maria Belén, Ventura, Marcello, Brown, Amanda C, Leblanc, Véronique, Bauer, Armin, Sanyal, Suparna, Cole, Stewart T, Lagrange, Sophie, Parish, Tanya, Manganelli, Riccardo
Published in Tuberculosis (Edinburgh, Scotland) (01.09.2016)
Published in Tuberculosis (Edinburgh, Scotland) (01.09.2016)
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Journal Article
Regulation of PfEMP1–VAR2CSA translation by a Plasmodium translation-enhancing factor
Chan, Sherwin, Frasch, Alejandra, Mandava, Chandra Sekhar, Ch'ng, Jun-Hong, Quintana, Maria del Pilar, Vesterlund, Mattias, Ghorbal, Mehdi, Joannin, Nicolas, Franzén, Oscar, Lopez-Rubio, Jose-Juan, Barbieri, Sonia, Lanzavecchia, Antonio, Sanyal, Suparna, Wahlgren, Mats
Published in Nature microbiology (08.05.2017)
Published in Nature microbiology (08.05.2017)
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Journal Article
Structure and function of FusB: an elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling
Guo, Xiaohu, Peisker, Kristin, Bäckbro, Kristina, Chen, Yang, Koripella, Ravi Kiran, Mandava, Chandra Sekhar, Sanyal, Suparna, Selmer, Maria
Published in Open biology (01.03.2012)
Published in Open biology (01.03.2012)
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Journal Article
Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation
Wang, Wei, Li, Wanqiu, Gee, Xueliang, Yan, Kaige, Mandava, Chandra Sekhar, Sanyal, Suparna, Gao, Ning
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.2020)
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Journal Article
Complementary charge-based interaction between the ribosomal-stalk protein L7/12 and IF2 is the key to rapid subunit association
Ge, Xueliang, Mandava, Chandra Sekhar, Lind, Christoffer, Åqvist, Johan, Sanyal, Suparna
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2018)
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Journal Article
Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis
Majumdar, Soneya, Emmerich, Andrew, Krakovka, Sascha, Mandava, Chandra Sekhar, Svärd, Staffan G, Sanyal, Suparna
Published in Nucleic acids research (24.04.2023)
Published in Nucleic acids research (24.04.2023)
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Journal Article
Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A
Fislage, Marcus, Zhang, Jingji, Brown, Zuben Patrick, Mandava, Chandra Sekhar, Sanyal, Suparna, Ehrenberg, Måns, Frank, Joachim
Published in Nucleic acids research (20.06.2018)
Published in Nucleic acids research (20.06.2018)
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Journal Article
The Ribosomal Stalk Plays a Key Role in IF2-Mediated Association of the Ribosomal Subunits
Huang, Chenhui, Mandava, Chandra Sekhar, Sanyal, Suparna
Published in Journal of molecular biology (28.05.2010)
Published in Journal of molecular biology (28.05.2010)
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Journal Article
Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-Tu(H84A)
Fislage, Marcus, Zhang, Jingji, Brown, Zuben Patrick, Mandava, Chandra Sekhar, Sanyal, Suparna, Ehrenberg, Måns, Frank, Joachim
Published in Nucleic acids research (2018)
Published in Nucleic acids research (2018)
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Journal Article
A conserved histidine in switch-II of EF-G moderates release of inorganic phosphate
Koripella, Ravi Kiran, Holm, Mikael, Dourado, Daniel, Mandava, Chandra Sekhar, Flores, Samuel, Sanyal, Suparna
Published in Scientific reports (12.08.2015)
Published in Scientific reports (12.08.2015)
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Journal Article
Bacterial ribosome requires multiple L12 dimers for efficient initiation and elongation of protein synthesis involving IF2 and EF-G
Mandava, Chandra Sekhar, Peisker, Kristin, Ederth, Josefine, Kumar, Ranjeet, Ge, Xueliang, Szaflarski, Witold, Sanyal, Suparna
Published in Nucleic acids research (01.03.2012)
Published in Nucleic acids research (01.03.2012)
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