Exploratory pharmacodynamics and efficacy of PF-06817024 in a Phase 1 study of patients with chronic rhinosinusitis and atopic dermatitis
Danto, Spencer I, Tsamandouras, Nikolaos, Reddy, Padma, Gilbert, Steven A, Mancuso, Jessica Y, Page, Karen, Beebe, Jean S, Peeva, Elena, Vincent, Michael S
Published in Allergy, asthma, and clinical immunology (30.08.2024)
Published in Allergy, asthma, and clinical immunology (30.08.2024)
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Journal Article
Discovery and Preclinical Characterization of 1‑Methyl‑3-(4‑methylpyridin‑3‑yl)‑6‑(pyridin‑2‑ylmethoxy)‑1H‑pyrazolo-[3,4‑b]pyrazine (PF470): A Highly Potent, Selective, and Efficacious Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator
Zhang, Lei, Balan, Gayatri, Barreiro, Gabriela, Boscoe, Brian P, Chenard, Lois K, Cianfrogna, Julie, Claffey, Michelle M, Chen, Laigao, Coffman, Karen J, Drozda, Susan E, Dunetz, Joshua R, Fonseca, Kari R, Galatsis, Paul, Grimwood, Sarah, Lazzaro, John T, Mancuso, Jessica Y, Miller, Emily L, Reese, Matthew R, Rogers, Bruce N, Sakurada, Isao, Skaddan, Marc, Smith, Deborah L, Stepan, Antonia F, Trapa, Patrick, Tuttle, Jamison B, Verhoest, Patrick R, Walker, Daniel P, Wright, Ann S, Zaleska, Margaret M, Zasadny, Kenneth, Shaffer, Christopher L
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
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Journal Article
Clinical trial of an inhibitor of RAGE-Aβ interactions in Alzheimer disease
Galasko, Douglas, Bell, Joanne, Mancuso, Jessica Y, Kupiec, James W, Sabbagh, Marwan N, van Dyck, Christopher, Thomas, Ronald G, Aisen, Paul S
Published in Neurology (29.04.2014)
Published in Neurology (29.04.2014)
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Journal Article
Prediction of Human Brain Penetration of P-glycoprotein and Breast Cancer Resistance Protein Substrates Using In Vitro Transporter Studies and Animal Models
Feng, Bo, Doran, Angela C., Di, Li, West, Mark A., Osgood, Sarah M., Mancuso, Jessica Y., Shaffer, Christopher L., Tremaine, Larry, Liras, Jennifer
Published in Journal of pharmaceutical sciences (01.08.2018)
Published in Journal of pharmaceutical sciences (01.08.2018)
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Journal Article
Behavioral Thermal Modeling for Microwave Power Amplifier Design
Mazeau, J., Sommet, R., Caban-Chastas, D., Gatard, E., Quere, R., Mancuso, Y.
Published in IEEE transactions on microwave theory and techniques (01.11.2007)
Published in IEEE transactions on microwave theory and techniques (01.11.2007)
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Journal Article
An evaluation of using rat-derived single-dose neuropharmacokinetic parameters to project accurately large animal unbound brain drug concentrations
Doran, Angela C, Osgood, Sarah M, Mancuso, Jessica Y, Shaffer, Christopher L
Published in Drug metabolism and disposition (01.11.2012)
Published in Drug metabolism and disposition (01.11.2012)
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Journal Article
A Confidence Interval for the Maximal Mean QT Interval Change Caused by Drug Effect
Eaton, Morris L., Muirhead, Robb J., Mancuso, Jessica Y., Kolluri, Sheela
Published in Drug information journal (01.07.2006)
Published in Drug information journal (01.07.2006)
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Journal Article
Quasi Inverse Class-F X-Band Highly Efficient Power Amplifier with 51.8% Peak PAE in SiGe
Redois, S., Kerherve, E., Ghiotto, A., Louis, B., Petit, V., Mancuso, Y.
Published in 2019 49th European Microwave Conference (EuMC) (01.10.2019)
Published in 2019 49th European Microwave Conference (EuMC) (01.10.2019)
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Conference Proceeding
Discovery and Characterization of (R)‑6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1‑c][1,4]oxazin-4(9H)‑one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates
Stepan, Antonia F, Claffey, Michelle M, Reese, Matthew R, Balan, Gayatri, Barreiro, Gabriela, Barricklow, Jason, Bohanon, Michael J, Boscoe, Brian P, Cappon, Gregg D, Chenard, Lois K, Cianfrogna, Julie, Chen, Laigao, Coffman, Karen J, Drozda, Susan E, Dunetz, Joshua R, Ghosh, Somraj, Hou, Xinjun, Houle, Christopher, Karki, Kapil, Lazzaro, John T, Mancuso, Jessica Y, Marcek, John M, Miller, Emily L, Moen, Mark A, O’Neil, Steven, Sakurada, Isao, Skaddan, Marc, Parikh, Vinod, Smith, Deborah L, Trapa, Patrick, Tuttle, Jamison B, Verhoest, Patrick R, Walker, Daniel P, Won, Annie, Wright, Ann S, Whritenour, Jessica, Zasadny, Kenneth, Zaleska, Margaret M, Zhang, Lei, Shaffer, Christopher L
Published in Journal of medicinal chemistry (28.09.2017)
Published in Journal of medicinal chemistry (28.09.2017)
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Journal Article
Quasi Inverse Class-F X-Band Highly Efficient Power Amplifier with 51.8% Peak PAE in SiGe
Redois, S., Kerherve, E., Ghiotto, A., Louis, B., Petit, V., Mancuso, Y.
Published in 2019 14th European Microwave Integrated Circuits Conference (EuMIC) (01.09.2019)
Published in 2019 14th European Microwave Integrated Circuits Conference (EuMIC) (01.09.2019)
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Conference Proceeding
Age‐Adjusted Exact Trend Tests in the Event of Rare Occurrences
Mancuso, Jessica Y., Ahn, Hongshik, Chen, James J., Mancuso, James P.
Published in Biometrics (01.06.2002)
Published in Biometrics (01.06.2002)
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Journal Article
Behavioral Power Amplifier Model considering Memory Effects dedicated to radar system simulation
Maziere, C., Gapillout, D., Gasseling, T., Decaesteke, T., Mancuso, Y.
Published in 2014 International Radar Conference (01.10.2014)
Published in 2014 International Radar Conference (01.10.2014)
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Conference Proceeding
Dispersion analysis of packaged MMIC amplifiers using the compression approach
Lesage, J.-M., Loison, R., Gillard, R., Barbier, T., Mancuso, Y.
Published in 34th European Microwave Conference, 2004 (2004)
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Published in 34th European Microwave Conference, 2004 (2004)
Conference Proceeding
T/R- Modules Technological and Technical Trends for Phased Array Antennas
Mancuso, Y., Gremillet, P., Lacomme, P.
Published in 2006 IEEE MTT-S International Microwave Symposium Digest (01.06.2006)
Published in 2006 IEEE MTT-S International Microwave Symposium Digest (01.06.2006)
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Conference Proceeding