Pharmacokinetics, efficacy and toxicity of different pegylated liposomal doxorubicin formulations in preclinical models: is a conventional bioequivalence approach sufficient to ensure therapeutic equivalence of pegylated liposomal doxorubicin products?
Mamidi, Rao N. V. S., Weng, Steve, Stellar, Susan, Wang, Charles, Yu, Ning, Huang, Tony, Tonelli, Alfred P., Kelley, Michael F., Angiuoli, Anthony, Fung, Man-Cheong
Published in Cancer chemotherapy and pharmacology (01.11.2010)
Published in Cancer chemotherapy and pharmacology (01.11.2010)
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In vitro and physiologically‐based pharmacokinetic based assessment of drug–drug interaction potential of canagliflozin
Mamidi, Rao N. V. S., Dallas, Shannon, Sensenhauser, Carlo, Lim, Heng Keang, Scheers, Ellen, Verboven, Peter, Cuyckens, Filip, Leclercq, Laurent, Evans, David C., Kelley, Michael F., Johnson, Mark D., Snoeys, Jan
Published in British journal of clinical pharmacology (01.05.2017)
Published in British journal of clinical pharmacology (01.05.2017)
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Niraparib with androgen receptor-axis-targeted therapy in patients with metastatic castration-resistant prostate cancer: safety and pharmacokinetic results from a phase 1b study (BEDIVERE)
Saad, Fred, Chi, Kim N., Shore, Neal D., Graff, Julie N., Posadas, Edwin M., Lattouf, Jean-Baptiste, Espina, Byron M., Zhu, Eugene, Yu, Alex, Hazra, Anasuya, De Meulder, Marc, Mamidi, Rao N. V. S., Bradic, Branislav, Francis, Peter, Hayreh, Vinny, Rezazadeh Kalebasty, Arash
Published in Cancer chemotherapy and pharmacology (01.07.2021)
Published in Cancer chemotherapy and pharmacology (01.07.2021)
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Prediction of the drug–drug interaction potential of the α1‐acid glycoprotein bound, CYP3A4/CYP2C9 metabolized oncology drug, erdafitinib
De Zwart, Loeckie, Snoeys, Jan, Jacobs, Frank, Li, Lilian Y., Poggesi, Italo, Verboven, Peter, Goris, Ivo, Scheers, Ellen, Wynant, Inneke, Monshouwer, Mario, Mamidi, Rao N. V. S.
Published in CPT: pharmacometrics and systems pharmacology (01.09.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.09.2021)
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Metabolism and Excretion of RWJ-333369 [1,2-Ethanediol, 1-(2-Chlorophenyl)-, 2-carbamate, (S)-] in Mice, Rats, Rabbits, and Dogs
MAMIDI, Rao N. V. S, MANNENS, Geert, ANNAERT, Pieter, HENDRICKX, Jan, GORIS, Ivo, BOCKX, Mark, JANSSEN, Cor G. M, KAO, Mark, KELLEY, Michael F, MEULDERMANS, Willem
Published in Drug metabolism and disposition (01.04.2007)
Published in Drug metabolism and disposition (01.04.2007)
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De-risking bio-therapeutics for possible drug interactions using cryopreserved human hepatocytes
Dallas, Shannon, Sensenhauser, Carlo, Batheja, Ameesha, Singer, Monica, Markowska, Maria, Zakszewski, Cindy, Mamidi, Rao N V S, McMillia, Michael, Han, Chao, Zhou, Honghui, Silva, Jose
Published in Current drug metabolism (01.09.2012)
Published in Current drug metabolism (01.09.2012)
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Tissue distribution and depletion kinetics of bortezomib and bortezomib-related radioactivity in male rats after single and repeated intravenous injection of 14C-bortezomib
HEMERYCK, Alex, GEERTS, Rita, DE COSTER, Roland, MONBALIU, Johan, HASSIER, Stephan, VERHAEGHE, Tom, DIELS, Luc, VERLUYTEN, Willy, VAN BEIJSTERVELDT, Ludy, MAMIDI, Rao N. V. S, JANSSEN, Cor
Published in Cancer chemotherapy and pharmacology (01.11.2007)
Published in Cancer chemotherapy and pharmacology (01.11.2007)
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Journal Article
Synthesis and Cyclooxygenase-2 Inhibiting Property of 1,5-Diarylpyrazoles with Substituted Benzenesulfonamide Moiety as Pharmacophore: Preparation of Sodium Salt for Injectable Formulation
Pal, Manojit, Madan, Manjula, Padakanti, Srinivas, Pattabiraman, Vijaya R, Kalleda, Srinivas, Vanguri, Akhila, Mullangi, Ramesh, Rao Mamidi, N. V. S, Casturi, Seshagiri R, Malde, Alpeshkumar, Gopalakrishnan, B, Yeleswarapu, Koteswar R
Published in Journal of medicinal chemistry (11.09.2003)
Published in Journal of medicinal chemistry (11.09.2003)
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Substituent activity relationship studies on new azolo benzoxazepinyl oxazolidinones
Das, Jagattaran, Sitaram Kumar, M., Subrahmanyam, D., Sastry, T.V.R.S., Prasad Narasimhulu, C., Laxman Rao, C.V., Kannan, M., Roshaiah, M., Awasthi, Riti, Patil, Santosh N., Sarnaik, H.M., Rao Mamidi, N.V.S., Selvakumar, N., Iqbal, Javed
Published in Bioorganic & medicinal chemistry (01.12.2006)
Published in Bioorganic & medicinal chemistry (01.12.2006)
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Synthesis of Conformationally Constrained Analogues of Linezolid: Structure−Activity Relationship (SAR) Studies on Selected Novel Tricyclic Oxazolidinones
Selvakumar, Natesan, Srinivas, Deekonda, Khera, Manoj Kumar, Kumar, Magadi Sitaram, Mamidi, Rao N. V. S, Sarnaik, Hemanth, Charavaryamath, Chandrashekar, Rao, Bonthu Srinivasa, Raheem, Mohammed A, Das, Jagattaran, Iqbal, Javed, Rajagopalan, Ramanujam
Published in Journal of medicinal chemistry (29.08.2002)
Published in Journal of medicinal chemistry (29.08.2002)
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Novel Antidiabetic and Hypolipidemic Agents. 5. Hydroxyl versus Benzyloxy Containing Chroman Derivatives
Reddy, K. Anji, Lohray, B. B, Bhushan, V, Reddy, A. Sekar, Mamidi, N. V. S. Rao, Reddy, P. Papi, Saibaba, V, Reddy, N. Jaipal, Suryaprakash, A, Misra, Parimal, Vikramadithyan, Reeba K, Rajagopalan, R
Published in Journal of medicinal chemistry (26.08.1999)
Published in Journal of medicinal chemistry (26.08.1999)
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In vitro metabolism of canagliflozin in human liver, kidney, intestine microsomes, and recombinant uridine diphosphate glucuronosyltransferases (UGT) and the effect of genetic variability of UGT enzymes on the pharmacokinetics of canagliflozin in humans
Francke, Stephan, Mamidi, Rao N V S, Solanki, Bhavna, Scheers, Ellen, Jadwin, Andrew, Favis, Reyna, Devineni, Damayanthi
Published in Journal of clinical pharmacology (01.09.2015)
Published in Journal of clinical pharmacology (01.09.2015)
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Niraparib Shows Superior Tissue Distribution and Efficacy in a Prostate Cancer Bone Metastasis Model Compared with Other PARP Inhibitors
Snyder, Linda A., Damle, Rajendra, Patel, Shefali, Bohrer, Jared, Fiorella, Anna, Driscoll, Jenny, Hawkins, Rebecca, Stratton, Christopher F., Manning, Carol D., Tatikola, Kanaka, Tryputsen, Volha, Packman, Kathryn, Mamidi, Rao N.V.S.
Published in Molecular cancer therapeutics (05.07.2022)
Published in Molecular cancer therapeutics (05.07.2022)
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Journal Article
Metabolism and disposition in rats, dogs, and humans of erdafitinib, an orally administered potent pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor
Scheers, Ellen, Borgmans, Carine, Keung, Chi, Bohets, Hilde, Wynant, Inneke, Poggesi, Italo, Cuyckens, Filip, Leclercq, Laurent, Mamidi, Rao N. V. S.
Published in Xenobiotica (01.02.2021)
Published in Xenobiotica (01.02.2021)
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Journal Article
Effect of ultraviolet B (302 nm) irradiation on viability, metabolic and detoxification functions of goat hepatocytes--in vitro study
Shakeel, Naseem Begum, Venkateshan, Vijayalakshmi, Parveen, Capoor, Adarsh K, Habeeb, Mohammed Aejaz, Khan, Ansar Ali, Muzeeb, Syed, Mamidi, N V S Rao, Khan, Aleem Ahmed, Habibullah, Chittoor Mohammed
Published in Molecular and cellular biochemistry (01.09.2005)
Published in Molecular and cellular biochemistry (01.09.2005)
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Journal Article
Metabolism and excretion of canagliflozin in mice, rats, dogs, and humans
Mamidi, Rao N V S, Cuyckens, Filip, Chen, Jie, Scheers, Ellen, Kalamaridis, Dennis, Lin, Ronghui, Silva, Jose, Sha, Sue, Evans, David C, Kelley, Michael F, Devineni, Damayanthi, Johnson, Mark D, Lim, Heng Keang
Published in Drug metabolism and disposition (01.05.2014)
Published in Drug metabolism and disposition (01.05.2014)
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Journal Article
Carcinogenicity in rats of the SGLT2 inhibitor canagliflozin
De Jonghe, Sandra, Proctor, Jim, Vinken, Petra, Feyen, Bianca, Wynant, Inneke, Marien, Dirk, Geys, Helena, Mamidi, Rao N.V.S., Johnson, Mark D.
Published in Chemico-biological interactions (05.12.2014)
Published in Chemico-biological interactions (05.12.2014)
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Journal Article
Effect of Fluconazole and Itraconazole on the Pharmacokinetics of Erdafitinib in Healthy Adults: A Randomized, Open-Label, Drug–Drug Interaction Study
Poggesi, Italo, Li, Lilian Y., Jiao, James, Hellemans, Peter, Rasschaert, Freya, de Zwart, Loeckie, Snoeys, Jan, De Meulder, Marc, Mamidi, Rao N. V. S., Ouellet, Daniele
Published in European journal of drug metabolism and pharmacokinetics (01.02.2020)
Published in European journal of drug metabolism and pharmacokinetics (01.02.2020)
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Novel indolo[2,1- b]quinazoline analogues as cytostatic agents: synthesis, biological evaluation and structure–activity relationship
Sharma, Vedula M., Prasanna, P., Adi Seshu, K.V., Renuka, B., Laxman Rao, C.V., Sunil Kumar, G., Narasimhulu, C.Prasad, Aravind Babu, P., Puranik, R.C., Subramanyam, D., Venkateswarlu, A., Rajagopal, Sriram, Kumar, K.B.Sunil, Rao, C.Seshagiri, Mamidi, N.V.S.Rao, Deevi, Dhanvanthri S., Ajaykumar, R., Rajagopalan, R.
Published in Bioorganic & medicinal chemistry letters (02.09.2002)
Published in Bioorganic & medicinal chemistry letters (02.09.2002)
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