Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin
KER YU, TORAL-BARZA, Lourdes, COLE, Derek C, ELLINGBOE, John, AYRAL-KALOUSTIAN, Semiramis, MANSOUR, Tarek S, GIBBONS, James J, ABRAHAM, Robert T, NOWAK, Pawel, ZASK, Arie, SHI, Celine, ZHANG, Wei-Guo, LUCAS, Judy, SHOR, Boris, KIM, Jamie, VERHEIJEN, Jeroen, CURRAN, Kevin, MALWITZ, David J
Published in Cancer research (Chicago, Ill.) (01.08.2009)
Published in Cancer research (Chicago, Ill.) (01.08.2009)
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ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin: Design and Synthesis of Highly Potent and Selective Pyrazolopyrimidines
Zask, Arie, Verheijen, Jeroen C, Curran, Kevin, Kaplan, Joshua, Richard, David J, Nowak, Pawel, Malwitz, David J, Brooijmans, Natasja, Bard, Joel, Svenson, Kristine, Lucas, Judy, Toral-Barza, Lourdes, Zhang, Wei-Guo, Hollander, Irwin, Gibbons, James J, Abraham, Robert T, Ayral-Kaloustian, Semiramis, Mansour, Tarek S, Yu, Ker
Published in Journal of medicinal chemistry (27.08.2009)
Published in Journal of medicinal chemistry (27.08.2009)
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Discovery of 4-Morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as Highly Potent and Selective ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin (mTOR): Optimization of the 6-Aryl Substituent
Verheijen, Jeroen C, Richard, David J, Curran, Kevin, Kaplan, Joshua, Lefever, Mark, Nowak, Pawel, Malwitz, David J, Brooijmans, Natasja, Toral-Barza, Lourdes, Zhang, Wei-Guo, Lucas, Judy, Hollander, Irwin, Ayral-Kaloustian, Semiramis, Mansour, Tarek S, Yu, Ker, Zask, Arie
Published in Journal of medicinal chemistry (24.12.2009)
Published in Journal of medicinal chemistry (24.12.2009)
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Discovery of Potent and Selective Inhibitors of the Mammalian Target of Rapamycin (mTOR) Kinase
Nowak, Pawel, Cole, Derek C, Brooijmans, Natasja, Bursavich, Matthew G, Curran, Kevin J, Ellingboe, John W, Gibbons, James J, Hollander, Irwin, Hu, YongBo, Kaplan, Joshua, Malwitz, David J, Toral-Barza, Lourdes, Verheijen, Jeroen C, Zask, Arie, Zhang, Wei-Guo, Yu, Ker
Published in Journal of medicinal chemistry (26.11.2009)
Published in Journal of medicinal chemistry (26.11.2009)
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Discovery of 4-Morpholino-6-aryl-1 H -pyrazolo[3,4- d ]pyrimidines as Highly Potent and Selective ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin (mTOR): Optimization of the 6-Aryl Substituent
Verheijen, Jeroen C., Richard, David J., Curran, Kevin, Kaplan, Joshua, Lefever, Mark, Nowak, Pawel, Malwitz, David J., Brooijmans, Natasja, Toral-Barza, Lourdes, Zhang, Wei-Guo, Lucas, Judy, Hollander, Irwin, Ayral-Kaloustian, Semiramis, Mansour, Tarek S., Yu, Ker, Zask, Arie
Published in Journal of medicinal chemistry (24.12.2009)
Published in Journal of medicinal chemistry (24.12.2009)
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N , N -Dimethyl-1-phenylsulfonyl-1 H -pyrrole-3-sulfonamide
Grossie, David A., Malwitz, David J., Ketcha, Daniel M.
Published in Acta crystallographica. Section E, Structure reports online (15.03.2006)
Published in Acta crystallographica. Section E, Structure reports online (15.03.2006)
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N,N‐Dimethyl‐1‐phenylsulfonyl‐1H‐pyrrole‐3‐sulfonamide
Grossie, David A., Malwitz, David J., Ketcha, Daniel M.
Published in Acta crystallographica. Section E, Structure reports online (01.03.2006)
Published in Acta crystallographica. Section E, Structure reports online (01.03.2006)
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COMPUESTOS DERIVADOS DE 1H-PIRAZOLO(3,4-D) PIRIMIDINA, INHIBIDORES DE CINASA mTOR Y CINASA PI3; PROCEDIMIENTO DE PREPARACION; COMPOSICION FARMACEUTICA QUE COMPRENDE A DICHOS COMPUESTOS; Y SU USO PARA EL TRATAMIENTO DE LA ATEROSCLEROSIS, TRASTORNOS OS
ZASK, ARIE; NOWAK, PAWEL WOJCIECH; VERHEIJEN, JEROEN; CURRAN, KEVIN J.; KAPLAN, JOSHUA; MALWITZ, DAVID; BURSAVICH, MATTH
Year of Publication 30.05.2008
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Year of Publication 30.05.2008
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