Turning a Quinoline-based Steroidal Anticancer Agent into Fluorescent Dye for its Tracking by Cell Imaging
Maltais, René, Roy, Jenny, Poirier, Donald
Published in ACS medicinal chemistry letters (13.05.2021)
Published in ACS medicinal chemistry letters (13.05.2021)
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Journal Article
Antisulfatase, Osteogenic, and Anticancer Activities of Steroid Sulfatase Inhibitor EO-33 in Mice
Poirier, Donald, Roy, Jenny, Maltais, René, Ayan, Diana
Published in Journal of medicinal chemistry (13.06.2019)
Published in Journal of medicinal chemistry (13.06.2019)
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Journal Article
Targeting Cytochrome P450 (CYP) 1B1 Enzyme with Four Series of A‑Ring Substituted Estrane Derivatives: Design, Synthesis, Inhibitory Activity, and Selectivity
Dutour, Raphaël, Roy, Jenny, Cortés-Benítez, Francisco, Maltais, René, Poirier, Donald
Published in Journal of medicinal chemistry (25.10.2018)
Published in Journal of medicinal chemistry (25.10.2018)
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Journal Article
Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone
Ngueta, Adrien Djiemeny, Roy, Jenny, Maltais, René, Poirier, Donald
Published in Molecules (Basel, Switzerland) (07.01.2023)
Published in Molecules (Basel, Switzerland) (07.01.2023)
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Journal Article
Minor chemical modifications of the aminosteroid derivative RM-581 lead to major impact on its anticancer activity, metabolic stability and aqueous solubility
Maltais, René, Perreault, Martin, Roy, Jenny, Poirier, Donald
Published in European journal of medicinal chemistry (15.02.2020)
Published in European journal of medicinal chemistry (15.02.2020)
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Journal Article
Total Synthesis of the Antidiabetic (Type 2) Lipid Mediator Protectin DX/PDX
Sancéau, Jean-Yves, Maltais, René, Poirier, Donald, Marette, André
Published in Journal of organic chemistry (18.01.2019)
Published in Journal of organic chemistry (18.01.2019)
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Journal Article
Formation of 5α-dihydrotestosterone from 5α-androstane-3α,17β-diol in prostate cancer LAPC-4 cells – Identifying inhibitors of non-classical pathways producing the most potent androgen
Boutin, Sophie, Roy, Jenny, Maltais, René, Poirier, Donald
Published in Bioorganic & medicinal chemistry letters (15.01.2020)
Published in Bioorganic & medicinal chemistry letters (15.01.2020)
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Journal Article
A- and D‑Ring Structural Modifications of an Androsterone Derivative Inhibiting 17β-Hydroxysteroid Dehydrogenase Type 3: Chemical Synthesis and Structure–Activity Relationships
Cortés-Benítez, Francisco, Roy, Jenny, Perreault, Martin, Maltais, René, Poirier, Donald
Published in Journal of medicinal chemistry (08.08.2019)
Published in Journal of medicinal chemistry (08.08.2019)
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Journal Article
16-Picolyl-androsterone derivative exhibits potent 17β-HSD3 inhibitory activity, improved metabolic stability and cytotoxic effect on various cancer cells: Synthesis, homology modeling and docking studies
Cortés-Benítez, Francisco, Roy, Jenny, Perreault, Martin, Maltais, René, Poirier, Donald
Published in The Journal of steroid biochemistry and molecular biology (01.06.2021)
Published in The Journal of steroid biochemistry and molecular biology (01.06.2021)
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Journal Article
Induction of Endoplasmic Reticulum Stress-Mediated Apoptosis by Aminosteroid RM-581 Efficiently Blocks the Growth of PC-3 Cancer Cells and Tumors Resistant or Not to Docetaxel
Maltais, René, Roy, Jenny, Perreault, Martin, Sato, Sachiko, Lévesque, Julie-Christine, Poirier, Donald
Published in International journal of molecular sciences (17.10.2021)
Published in International journal of molecular sciences (17.10.2021)
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Journal Article
A new nonestrogenic steroidal inhibitor of 17β-hydroxysteroid dehydrogenase type I blocks the estrogen-dependent breast cancer tumor growth induced by estrone
Ayan, Diana, Maltais, René, Roy, Jenny, Poirier, Donald
Published in Molecular cancer therapeutics (01.10.2012)
Published in Molecular cancer therapeutics (01.10.2012)
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Journal Article
Identification of steroidal derivatives inhibiting the transformations of allopregnanolone and estradiol by 17β-hydroxysteroid dehydrogenase type 10
Boutin, Sophie, Roy, Jenny, Maltais, René, Alata, Wael, Calon, Frédéric, Poirier, Donald
Published in Bioorganic & medicinal chemistry letters (01.12.2018)
Published in Bioorganic & medicinal chemistry letters (01.12.2018)
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Journal Article
Pharmacokinetic profile of PBRM in rodents, a first selective covalent inhibitor of 17β-HSD1 for breast cancer and endometriosis treatments
Maltais, René, Trottier, Alexandre, Roy, Jenny, Ayan, Diana, Bertrand, Nicolas, Poirier, Donald
Published in The Journal of steroid biochemistry and molecular biology (01.04.2018)
Published in The Journal of steroid biochemistry and molecular biology (01.04.2018)
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Journal Article