Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming
Solé-Boldo, Llorenç, Raddatz, Günter, Schütz, Sabrina, Mallm, Jan-Philipp, Rippe, Karsten, Lonsdorf, Anke S, Rodríguez-Paredes, Manuel, Lyko, Frank
Published in Communications biology (23.04.2020)
Published in Communications biology (23.04.2020)
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Journal Article
Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single-cell transcriptomics
Tirier, Stephan M, Mallm, Jan-Philipp, Steiger, Simon, Poos, Alexandra M, Awwad, Mohamed H S, Giesen, Nicola, Casiraghi, Nicola, Susak, Hana, Bauer, Katharina, Baumann, Anja, John, Lukas, Seckinger, Anja, Hose, Dirk, Müller-Tidow, Carsten, Goldschmidt, Hartmut, Stegle, Oliver, Hundemer, Michael, Weinhold, Niels, Raab, Marc S, Rippe, Karsten
Published in Nature communications (29.11.2021)
Published in Nature communications (29.11.2021)
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Journal Article
Haematopoietic stem cells in perisinusoidal niches are protected from ageing
Saçma, Mehmet, Pospiech, Johannes, Bogeska, Ruzhica, de Back, Walter, Mallm, Jan-Philipp, Sakk, Vadim, Soller, Karin, Marka, Gina, Vollmer, Angelika, Karns, Rebekah, Cabezas-Wallscheid, Nina, Trumpp, Andreas, Méndez-Ferrer, Simón, Milsom, Michael D, Mulaw, Medhanie A, Geiger, Hartmut, Florian, Maria Carolina
Published in Nature cell biology (01.11.2019)
Published in Nature cell biology (01.11.2019)
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Journal Article
Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF
Delacher, Michael, Imbusch, Charles D., Hotz-Wagenblatt, Agnes, Mallm, Jan-Philipp, Bauer, Katharina, Simon, Malte, Riegel, Dania, Rendeiro, André F., Bittner, Sebastian, Sanderink, Lieke, Pant, Asmita, Schmidleithner, Lisa, Braband, Kathrin L., Echtenachter, Bernd, Fischer, Alexander, Giunchiglia, Valentina, Hoffmann, Petra, Edinger, Matthias, Bock, Christoph, Rehli, Michael, Brors, Benedikt, Schmidl, Christian, Feuerer, Markus
Published in Immunity (Cambridge, Mass.) (18.02.2020)
Published in Immunity (Cambridge, Mass.) (18.02.2020)
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Journal Article
Glioblastoma initiating cells are sensitive to histone demethylase inhibition due to epigenetic deregulation
Mallm, Jan‐Philipp, Windisch, Paul, Biran, Alva, Gal, Zoltan, Schumacher, Sabrina, Glass, Rainer, Herold‐Mende, Christel, Meshorer, Eran, Barbus, Martje, Rippe, Karsten
Published in International journal of cancer (01.03.2020)
Published in International journal of cancer (01.03.2020)
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Journal Article
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
Brocks, David, Schmidt, Christopher R, Daskalakis, Michael, Jang, Hyo Sik, Shah, Nakul M, Li, Daofeng, Li, Jing, Zhang, Bo, Hou, Yiran, Laudato, Sara, Lipka, Daniel B, Schott, Johanna, Bierhoff, Holger, Assenov, Yassen, Helf, Monika, Ressnerova, Alzbeta, Islam, Md Saiful, Lindroth, Anders M, Haas, Simon, Essers, Marieke, Imbusch, Charles D, Brors, Benedikt, Oehme, Ina, Witt, Olaf, Lübbert, Michael, Mallm, Jan-Philipp, Rippe, Karsten, Will, Rainer, Weichenhan, Dieter, Stoecklin, Georg, Gerhäuser, Clarissa, Oakes, Christopher C, Wang, Ting, Plass, Christoph
Published in Nature genetics (01.07.2017)
Published in Nature genetics (01.07.2017)
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Journal Article
Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels
Roider, Tobias, Seufert, Julian, Uvarovskii, Alexey, Frauhammer, Felix, Bordas, Marie, Abedpour, Nima, Stolarczyk, Marta
Published in Nature cell biology (01.07.2020)
Published in Nature cell biology (01.07.2020)
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Journal Article
Specificity, propagation, and memory of pericentric heterochromatin
Müller‐Ott, Katharina, Erdel, Fabian, Matveeva, Anna, Mallm, Jan‐Philipp, Rademacher, Anne, Hahn, Matthias, Bauer, Caroline, Zhang, Qin, Kaltofen, Sabine, Schotta, Gunnar, Höfer, Thomas, Rippe, Karsten
Published in Molecular systems biology (01.08.2014)
Published in Molecular systems biology (01.08.2014)
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Journal Article
Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children
Bauer, Tobias, Trump, Saskia, Ishaque, Naveed, Thürmann, Loreen, Gu, Lei, Bauer, Mario, Bieg, Matthias, Gu, Zuguang, Weichenhan, Dieter, Mallm, Jan‐Philipp, Röder, Stefan, Herberth, Gunda, Takada, Eiko, Mücke, Oliver, Winter, Marcus, Junge, Kristin M, Grützmann, Konrad, Rolle‐Kampczyk, Ulrike, Wang, Qi, Lawerenz, Christian, Borte, Michael, Polte, Tobias, Schlesner, Matthias, Schanne, Michaela, Wiemann, Stefan, Geörg, Christina, Stunnenberg, Hendrik G, Plass, Christoph, Rippe, Karsten, Mizuguchi, Junichiro, Herrmann, Carl, Eils, Roland, Lehmann, Irina
Published in Molecular systems biology (01.03.2016)
Published in Molecular systems biology (01.03.2016)
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Journal Article
HP1 Is Involved in Regulating the Global Impact of DNA Methylation on Alternative Splicing
Yearim, Ahuvi, Gelfman, Sahar, Shayevitch, Ronna, Melcer, Shai, Glaich, Ohad, Mallm, Jan-Philipp, Nissim-Rafinia, Malka, Cohen, Ayelet-Hashahar S., Rippe, Karsten, Meshorer, Eran, Ast, Gil
Published in Cell reports (Cambridge) (24.02.2015)
Published in Cell reports (Cambridge) (24.02.2015)
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Journal Article
Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation
Erkek, Serap, Johann, Pascal D., Finetti, Martina A., Drosos, Yiannis, Chou, Hsien-Chao, Zapatka, Marc, Sturm, Dominik, Jones, David T.W., Korshunov, Andrey, Rhyzova, Marina, Wolf, Stephan, Mallm, Jan-Philipp, Beck, Katja, Witt, Olaf, Kulozik, Andreas E., Frühwald, Michael C., Northcott, Paul A., Korbel, Jan O., Lichter, Peter, Eils, Roland, Gajjar, Amar, Roberts, Charles W.M., Williamson, Daniel, Hasselblatt, Martin, Chavez, Lukas, Pfister, Stefan M., Kool, Marcel
Published in Cancer cell (14.01.2019)
Published in Cancer cell (14.01.2019)
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Journal Article
Differentiation‐related epigenomic changes define clinically distinct keratinocyte cancer subclasses
Solé‐Boldo, Llorenç, Raddatz, Günter, Gutekunst, Julian, Gilliam, Oliver, Bormann, Felix, Liberio, Michelle S, Hasche, Daniel, Antonopoulos, Wiebke, Mallm, Jan‐Philipp, Lonsdorf, Anke S, Rodríguez‐Paredes, Manuel, Lyko, Frank
Published in Molecular systems biology (01.09.2022)
Published in Molecular systems biology (01.09.2022)
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Journal Article
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
Mallm, Jan‐Philipp, Iskar, Murat, Ishaque, Naveed, Klett, Lara C, Kugler, Sabrina J, Muino, Jose M, Teif, Vladimir B, Poos, Alexandra M, Großmann, Sebastian, Erdel, Fabian, Tavernari, Daniele, Koser, Sandra D, Schumacher, Sabrina, Brors, Benedikt, König, Rainer, Remondini, Daniel, Vingron, Martin, Stilgenbauer, Stephan, Lichter, Peter, Zapatka, Marc, Mertens, Daniel, Rippe, Karsten
Published in Molecular systems biology (01.05.2019)
Published in Molecular systems biology (01.05.2019)
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Journal Article
scSNPdemux: a sensitive demultiplexing pipeline using single nucleotide polymorphisms for improved pooled single-cell RNA sequencing analysis
Wong, John K. L, Jassowicz, Lena, Herold-Mende, Christel, Seiffert, Martina, Mallm, Jan-Philipp, Lichter, Peter, Zapatka, Marc
Published in BMC bioinformatics (31.08.2023)
Published in BMC bioinformatics (31.08.2023)
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Journal Article
Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia
Vu, Therese, Straube, Jasmin, Porter, Amy H, Bywater, Megan, Song, Axia, Ling, Victoria, Cooper, Leanne, Pali, Gabor, Bruedigam, Claudia, Jacquelin, Sebastien, Green, Joanne, Magor, Graham, Perkins, Andrew, Chalk, Alistair M, Walkley, Carl R, Heidel, Florian H, Mukhopadhyay, Pamela, Cloonan, Nicole, Gröschel, Stefan, Mallm, Jan-Philipp, Fröhling, Stefan, Scholl, Claudia, Lane, Steven W
Published in Nature communications (15.06.2020)
Published in Nature communications (15.06.2020)
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Journal Article
Retrieving Chromatin Patterns from Deep Sequencing Data Using Correlation Functions
Molitor, Jana, Mallm, Jan-Philipp, Rippe, Karsten, Erdel, Fabian
Published in Biophysical journal (07.02.2017)
Published in Biophysical journal (07.02.2017)
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Journal Article
Pheno-seq - linking visual features and gene expression in 3D cell culture systems
Tirier, Stephan M, Park, Jeongbin, Preußer, Friedrich, Amrhein, Lisa, Gu, Zuguang, Steiger, Simon, Mallm, Jan-Philipp, Krieger, Teresa, Waschow, Marcel, Eismann, Björn, Gut, Marta, Gut, Ivo G, Rippe, Karsten, Schlesner, Matthias, Theis, Fabian, Fuchs, Christiane, Ball, Claudia R, Glimm, Hanno, Eils, Roland, Conrad, Christian
Published in Scientific reports (26.08.2019)
Published in Scientific reports (26.08.2019)
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Journal Article
Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells
Mattout, Anna, Aaronson, Yair, Sailaja, Badi Sri, Raghu Ram, Edupuganti V, Harikumar, Arigela, Mallm, Jan-Philipp, Sim, Kae Hwan, Nissim-Rafinia, Malka, Supper, Emmanuelle, Singh, Prim B, Sze, Siu Kwan, Gasser, Susan M, Rippe, Karsten, Meshorer, Eran
Published in Genome Biology (28.09.2015)
Published in Genome Biology (28.09.2015)
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Journal Article
Increased vitamin D levels at birth and in early infancy increase offspring allergy risk—evidence for involvement of epigenetic mechanisms
Junge, Kristin M., PhD, Bauer, Tobias, PhD, Geissler, Stefanie, PhD, Hirche, Frank, PhD, Thürmann, Loreen, MSc, Bauer, Mario, MD, Trump, Saskia, PhD, Bieg, Matthias, MSc, Weichenhan, Dieter, PhD, Gu, Lei, PhD, Mallm, Jan-Philipp, PhD, Ishaque, Naveed, PhD, Mücke, Oliver, Röder, Stefan, PhD, Herberth, Gunda, PhD, Diez, Ulrike, MD, Borte, Michael, MD, Rippe, Karsten, PhD, Plass, Christoph, PhD, Hermann, Carl, PhD, Stangl, Gabriele I., PhD, Eils, Roland, PhD, Lehmann, Irina, PhD
Published in Journal of allergy and clinical immunology (01.02.2016)
Published in Journal of allergy and clinical immunology (01.02.2016)
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Journal Article