SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids
Pellegrini, Laura, Albecka, Anna, Mallery, Donna L., Kellner, Max J., Paul, David, Carter, Andrew P., James, Leo C., Lancaster, Madeline A.
Published in Cell Stem Cell (03.12.2020)
Published in Cell Stem Cell (03.12.2020)
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Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion
Papa, Guido, Mallery, Donna L, Albecka, Anna, Welch, Lawrence G, Cattin-Ortolá, Jérôme, Luptak, Jakub, Paul, David, McMahon, Harvey T, Goodfellow, Ian G, Carter, Andrew, Munro, Sean, James, Leo C
Published in PLoS pathogens (25.01.2021)
Published in PLoS pathogens (25.01.2021)
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BRCA1 Is a Histone-H2A-Specific Ubiquitin Ligase
Kalb, Reinhard, Mallery, Donna L., Larkin, Conor, Huang, Jeffrey T.J., Hiom, Kevin
Published in Cell reports (Cambridge) (21.08.2014)
Published in Cell reports (Cambridge) (21.08.2014)
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Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21
McEwan, William A, Tam, Jerry C H, Watkinson, Ruth E, Bidgood, Susanna R, Mallery, Donna L, James, Leo C
Published in Nature immunology (01.04.2013)
Published in Nature immunology (01.04.2013)
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Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)
Mallery, Donna L., McEwan, William A., Bidgood, Susanna R., Towers, Greg J., Johnson, Chris M., James, Leo C., Fearon, Douglas T.
Published in Proceedings of the National Academy of Sciences - PNAS (16.11.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (16.11.2010)
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A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly
Renner, Nadine, Mallery, Donna L, Faysal, K M Rifat, Peng, Wang, Jacques, David A, Böcking, Till, James, Leo C
Published in PLoS pathogens (01.02.2021)
Published in PLoS pathogens (01.02.2021)
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Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21
Fletcher, Adam J., Mallery, Donna L., Watkinson, Ruth E., Dickson, Claire F., James, Leo C.
Published in Proceedings of the National Academy of Sciences - PNAS (11.08.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (11.08.2015)
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IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis
Mallery, Donna L, Márquez, Chantal L, McEwan, William A, Dickson, Claire F, Jacques, David A, Anandapadamanaban, Madhanagopal, Bichel, Katsiaryna, Towers, Gregory J, Saiardi, Adolfo, Böcking, Till, James, Leo C
Published in eLife (31.05.2018)
Published in eLife (31.05.2018)
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A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases
Kiss, Leo, Zeng, Jingwei, Dickson, Claire F., Mallery, Donna L., Yang, Ji-Chun, McLaughlin, Stephen H., Boland, Andreas, Neuhaus, David, James, Leo C.
Published in Nature communications (03.10.2019)
Published in Nature communications (03.10.2019)
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Cellular IP6 Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP6 Are Attenuated for Infection and Replication
Mallery, Donna L., Faysal, K.M. Rifat, Kleinpeter, Alex, Wilson, Miranda S.C., Vaysburd, Marina, Fletcher, Adam J., Novikova, Mariia, Böcking, Till, Freed, Eric O., Saiardi, Adolfo, James, Leo C.
Published in Cell reports (Cambridge) (17.12.2019)
Published in Cell reports (Cambridge) (17.12.2019)
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Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21
Dickson, Claire, Fletcher, Adam J, Vaysburd, Marina, Yang, Ji-Chun, Mallery, Donna L, Zeng, Jingwei, Johnson, Christopher M, McLaughlin, Stephen H, Skehel, Mark, Maslen, Sarah, Cruickshank, James, Huguenin-Dezot, Nicolas, Chin, Jason W, Neuhaus, David, James, Leo C
Published in eLife (18.04.2018)
Published in eLife (18.04.2018)
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TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing
Luptak, Jakub, Mallery, Donna L, Jahun, Aminu S, Albecka, Anna, Clift, Dean, Ather, Osaid, Slodkowicz, Greg, Goodfellow, Ian, James, Leo C
Published in Viruses (23.07.2022)
Published in Viruses (23.07.2022)
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Intracellular antibody-mediated immunity and the role of TRIM21
McEwan, William A., Mallery, Donna L., Rhodes, David A., Trowsdale, John, James, Leo C.
Published in BioEssays (01.11.2011)
Published in BioEssays (01.11.2011)
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A Phosphorylated Form of Mel-18 Targets the Ring1B Histone H2A Ubiquitin Ligase to Chromatin
Elderkin, Sarah, Maertens, Goedele N., Endoh, Mitsuhiro, Mallery, Donna L., Morrice, Nick, Koseki, Haruhiko, Peters, Gordon, Brockdorff, Neil, Hiom, Kevin
Published in Molecular cell (12.10.2007)
Published in Molecular cell (12.10.2007)
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HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly
Renner, Nadine, Kleinpeter, Alex, Mallery, Donna L., Albecka, Anna, Rifat Faysal, K. M., Böcking, Till, Saiardi, Adolfo, Freed, Eric O., James, Leo C.
Published in Nature structural & molecular biology (01.03.2023)
Published in Nature structural & molecular biology (01.03.2023)
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The Effect of Inositol Hexakisphosphate on HIV-1 Particle Production and Infectivity can be Modulated by Mutations that Affect the Stability of the Immature Gag Lattice
Kleinpeter, Alex B., Zhu, Yanan, Mallery, Donna L., Ablan, Sherimay D., Chen, Long, Hardenbrook, Nathan, Saiardi, Adolfo, James, Leo C., Zhang, Peijun, Freed, Eric O.
Published in Journal of molecular biology (01.06.2023)
Published in Journal of molecular biology (01.06.2023)
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