Cloning, expression, and characterization of the human eosinophil eotaxin receptor
Daugherty, B L, Siciliano, S J, DeMartino, J A, Malkowitz, L, Sirotina, A, Springer, M S
Published in The Journal of experimental medicine (01.05.1996)
Published in The Journal of experimental medicine (01.05.1996)
Get full text
Journal Article
Two-Site Binding of C5a by its Receptor: An Alternative Binding Paradigm for G Protein-Coupled Receptors
Siciliano, Salvatore J., Rollins, Thomas E., DeMartino, Julie, Konteatis, Zenon, Malkowitz, Lorraine, Van Riper, Gail, Bondy, Steven, Rosen, Hugh, Springer, Martin S.
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.1994)
Get full text
Journal Article
Mitochondrial benzodiazepine receptors mediate inhibition of mitochondrial respiratory control
HIRSCH, J. D, BEYER, C. F, MALKOWITZ, L, BEER, B, BLUME, A. J
Published in Molecular pharmacology (01.01.1989)
Get full text
Published in Molecular pharmacology (01.01.1989)
Journal Article
Characterization of ligand binding to mitochondrial benzodiazepine receptors
HIRSCH, J. D, BEYER, C. F, MALKOWITZ, L, LOULLIS, C. C, BLUME, A. J
Published in Molecular pharmacology (01.01.1989)
Get full text
Published in Molecular pharmacology (01.01.1989)
Journal Article
A nonpeptidic agonist ligand of the human C5a receptor: Synthesis, binding affinity optimization and functional characterization
de Laszlo, S.E., Allen, E.E., Li, B., Ondeyka, D., Rivero, R., Malkowitz, L., Molineaux, C., Siciliano, S.J., Springer, M.S., Greenlee, W.J., Mantlo, N.
Published in Bioorganic & medicinal chemistry letters (21.01.1997)
Published in Bioorganic & medicinal chemistry letters (21.01.1997)
Get full text
Journal Article
Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties
Kim, Dooseop, Wang, Liping, Hale, Jeffrey J., Lynch, Christopher L., Budhu, Richard J., MacCoss, Malcolm, Mills, Sander G., Malkowitz, Lorraine, Gould, Sandra L., DeMartino, Julie A., Springer, Martin S., Hazuda, Daria, Miller, Michael, Kessler, Joseph, Hrin, Renee C., Carver, Gwen, Carella, Anthony, Henry, Karen, Lineberger, Janet, Schleif, William A., Emini, Emilio A.
Published in Bioorganic & medicinal chemistry letters (15.04.2005)
Published in Bioorganic & medicinal chemistry letters (15.04.2005)
Get full text
Journal Article
Two-site binding of C5a by its receptor: analternative binding paradigm for G protein-coupled receptors
Siciliano, S J, Rollins, T E, DeMartino, J, Konteatis, Z, Malkowitz, L, Van Riper, G, Bondy, S, Rosen, H, Springer, M S
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.1994)
Get full text
Journal Article
CCR5, CXCR4, and CD4 Are Clustered and Closely Apposed on Microvilli of Human Macrophages and T Cells
Singer, I I, Scott, S, Kawka, D W, Chin, J, Daugherty, B L, DeMartino, J A, DiSalvo, J, Gould, S L, Lineberger, J E, Malkowitz, L, Miller, M D, Mitnaul, L, Siciliano, S J, Staruch, M J, Williams, H R, Zweerink, H J, Springer, M S
Published in Journal of Virology (01.04.2001)
Published in Journal of Virology (01.04.2001)
Get full text
Journal Article
Isolation and Structure of Antagonists of Chemokine Receptor (CCR5)
Jayasuriya, Hiranthi, Herath, Kithsiri B, Ondeyka, John G, Polishook, Jon D, Bills, Gerald F, Dombrowski, Anne W, Springer, Marty S, Siciliano, Sal, Malkowitz, Lorraine, Sanchez, Manuel, Guan, Ziqiang, Tiwari, Suroojnauth, Stevenson, Dennis W, Borris, Robert P, Singh, Sheo B
Published in Journal of natural products (Washington, D.C.) (01.06.2004)
Published in Journal of natural products (Washington, D.C.) (01.06.2004)
Get full text
Journal Article
Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 4: synthesis and structure–Activity relationships for 1-[ N-(Methyl)- N-(phenylsulfonyl)amino]-2-(phenyl)-4-(4-( N-(alkyl)- N-(benzyloxycarbonyl)amino)piperidin-1-yl)butanes
Finke, Paul E., Oates, Bryan, Mills, Sander G., MacCoss, Malcolm, Malkowitz, Lorraine, Springer, Martin S., Gould, Sandra L., DeMartino, Julie A., Carella, Anthony, Carver, Gwen, Holmes, Karen, Danzeisen, Renee, Hazuda, Daria, Kessler, Joseph, Lineberger, Janet, Miller, Michael, Schleif, William A., Emini, Emilio A.
Published in Bioorganic & medicinal chemistry letters (17.09.2001)
Published in Bioorganic & medicinal chemistry letters (17.09.2001)
Get full text
Journal Article
Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 1: Discovery and initial structure-activity relationships for 1-amino-2-phenyl-4-(piperidin-1-yl)butanes
DORN, Conrad P, FINKE, Paul E, DEMARTINO, Julie A, SICILIANO, Salvatore J, CARELLA, Anthony, CARVER, Gwen, HOLMES, Karen, DANZEISEN, Renee, HAZUDA, Daria, KESSLER, Joseph, LINEBERGER, Janet, MILLER, Michael, OATES, Bryan, SCHLEIF, William A, EMINI, Emilio A, BUDHU, Richard J, MILLS, Sander G, MACCOSS, Malcolm, MALKOWITZ, Lorraine, SPRINGER, Martin S, DAUGHERTY, Bruce L, GOULD, Sandra L
Published in Bioorganic & medicinal chemistry letters (22.01.2001)
Published in Bioorganic & medicinal chemistry letters (22.01.2001)
Get full text
Journal Article
Diabetes and renal calcium binding protein in the rat
Schedl, H P, Christakos, S, Wilson, H D, Malkowitz, L, Horst, R L
Published in Proceedings of the Society for Experimental Biology and Medicine (01.10.1984)
Published in Proceedings of the Society for Experimental Biology and Medicine (01.10.1984)
Get more information
Journal Article
Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 1: Discovery and sar study of 4-pyrazolylpiperidine side chains
SHEN, Dong-Ming, MIN SHU, CARELLA, Anthony, CARVER, Gwen, HOLMES, Karen, SCHLEIF, William A, DANZEISEN, Renee, HAZUDA, Daria, KESSLER, Joseph, LINEBERGER, Janet, MILLER, Michael D, EMINI, Emilio A, MILLS, Sander G, CHAPMAN, Kevin T, MALKOWITZ, Lorraine, SPRINGER, Martin S, GOULD, Sandra L, DEMARTINO, Julie A, SICILIANO, Salvatore J, KWEI, Gloria Y
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
Get full text
Journal Article
1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 1: discovery of the pyrrolidine scaffold and determination of its stereochemical requirements
Hale, Jeffrey J., Budhu, Richard J., Mills, Sander G., MacCoss, Malcolm, Malkowitz, Lorraine, Siciliano, Salvatore, Gould, Sandra L., DeMartino, Julie A., Springer, Martin S.
Published in Bioorganic & medicinal chemistry letters (04.06.2001)
Published in Bioorganic & medicinal chemistry letters (04.06.2001)
Get full text
Journal Article
Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 2: Structure-activity relationships for substituted 2-aryl-1-[N-(methyl)-N-(phenylsulfonyl)amino]-4-(piperidin-1-yl)butanes
FINKE, Paul E, MEURER, Laura C, SICILIANO, Salvatore J, CARELLA, Anthony, CARVER, Gwen, HOLMES, Karen, DANZEISEN, Renee, HAZUDA, Daria, KESSLER, Joseph, LINEBERGER, Janet, MILLER, Michael, SCHLEIF, William A, OATES, Bryan, EMINI, Emilio A, MILLS, Sander G, MACCOSS, Malcolm, MALKOWITZ, Lorraine, SPRINGER, Martin S, DAUGHERTY, Bruce L, GOULD, Sandra L, DEMARTINO, Julie A
Published in Bioorganic & medicinal chemistry letters (22.01.2001)
Published in Bioorganic & medicinal chemistry letters (22.01.2001)
Get full text
Journal Article
Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 2: Discovery of potent, selective, and orally bioavailable compounds
SHEN, Dong-Ming, MIN SHU, GOULD, Sandra L, DEMARTINO, Julie A, SICILIANO, Salvatore J, LYONS, Kathy, PIVNICHNY, James V, KWEI, Gloria Y, CARELLA, Anthony, CARVER, Gwen, HOLMES, Karen, SCHLEIF, William A, WILLOUGHBY, Christopher A, DANZEISEN, Renee, HAZUDA, Daria, KESSLER, Joseph, LINEBERGER, Janet, MILLER, Michael D, EMINI, Emilio A, SHAH, Shrenik, LYNCH, Christopher L, HALE, Jeffrey J, MILLS, Sander G, CHAPMAN, Kevin T, MALKOWITZ, Lorraine, SPRINGER, Martin S
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
Get full text
Journal Article
1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 2: lead optimization affording selective, orally bioavailable compounds with potent Anti-HIV activity
Hale, Jeffrey J., Budhu, Richard J., Holson, Edward B., Finke, Paul E., Oates, Bryan, Mills, Sander G., MacCoss, Malcolm, Gould, Sandra L., DeMartino, Julie A., Springer, Martin S., Siciliano, Salvatore, Malkowitz, Lorraine, Schleif, William A., Hazuda, Daria, Miller, Michael, Kessler, Joseph, Danzeisen, Renee, Holmes, Karen, Lineberger, Janet, Carella, Anthony, Carver, Gwen, Emini, Emilio
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
Get full text
Journal Article
Synthesis and evaluation of CCR5 antagonists containing modified 4-piperidinyl-2-phenyl-1-(phenylsulfonylamino)-butane
Shah, Shrenik K., Chen, Natalie, Guthikonda, Ravindra N., Mills, Sander G., Malkowitz, Lorraine, Springer, Martin S., Gould, Sandra L., DeMartino, Julie A., Carella, Anthony, Carver, Gwen, Holmes, Karen, Schleif, William A., Danzeisen, Renee, Hazuda, Daria, Kessler, Joseph, Lineberger, Janet, Miller, Michael, Emini, Emilio A., MacCoss, Malcolm
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
Get full text
Journal Article
Combinatorial synthesis of CCR5 antagonists
Willoughby, Christopher A, Berk, Scott C, Rosauer, Keith G, Degrado, Silvia, Chapman, Kevin T, Gould, Sandra L, Springer, Martin S, Malkowitz, Lorraine, Schleif, William A, Hazuda, Daria, Miller, Michael, Kessler, Joseph, Danzeisen, Renee, Holmes, Karen, Lineberger, Janet, Carella, Anthony, Carver, Gwen, Emini, Emilio A
Published in Bioorganic & medicinal chemistry letters (17.12.2001)
Published in Bioorganic & medicinal chemistry letters (17.12.2001)
Get full text
Journal Article
Combinatorial synthesis of 3-(Amidoalkyl) and 3-(Aminoalkyl)-2-arylindole derivatives: discovery of potent ligands for a variety of G-protein coupled receptors
Willoughby, Christopher A, Hutchins, Steven M, Rosauer, Keith G, Dhar, Madhumeeta J, Chapman, Kevin T, Chicchi, Gary G, Sadowski, Sharon, Weinberg, David H, Patel, Smita, Malkowitz, Lorraine, Di Salvo, Jerry, Pacholok, Stephen G, Cheng, Kang
Published in Bioorganic & medicinal chemistry letters (07.01.2002)
Published in Bioorganic & medicinal chemistry letters (07.01.2002)
Get full text
Journal Article