CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites
Jayavaradhan, Rajeswari, Pillis, Devin M., Goodman, Michael, Zhang, Fan, Zhang, Yue, Andreassen, Paul R., Malik, Punam
Published in Nature communications (28.06.2019)
Published in Nature communications (28.06.2019)
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Journal Article
Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia
Niss, Omar, Fleck, Robert, Makue, Fowe, Alsaied, Tarek, Desai, Payal, Towbin, Jeffrey A., Malik, Punam, Taylor, Michael D., Quinn, Charles T.
Published in Blood (13.07.2017)
Published in Blood (13.07.2017)
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Journal Article
Strategies for precise gene edits in mammalian cells
Fichter, Katye M., Setayesh, Tahereh, Malik, Punam
Published in Molecular therapy. Nucleic acids (13.06.2023)
Published in Molecular therapy. Nucleic acids (13.06.2023)
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Journal Article
Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease
George, Alex, Pushkaran, Suvarnamala, Konstantinidis, Diamantis G., Koochaki, Sebastian, Malik, Punam, Mohandas, Narla, Zheng, Yi, Joiner, Clinton H., Kalfa, Theodosia A.
Published in Blood (14.03.2013)
Published in Blood (14.03.2013)
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Journal Article
Cardiac pathophysiology in sickle cell disease
Gbotosho, Oluwabukola Temitope, Taylor, Michael, Malik, Punam
Published in Journal of thrombosis and thrombolysis (01.07.2021)
Published in Journal of thrombosis and thrombolysis (01.07.2021)
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Journal Article
G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment
Chen, Xiaoji, Skutt-Kakaria, Kyobi, Davison, Jerry, Ou, Yang-Li, Choi, Edward, Malik, Punam, Loeb, Keith, Wood, Brent, Georges, George, Torok-Storb, Beverly, Paddison, Patrick J
Published in Genes & development (15.11.2012)
Published in Genes & development (15.11.2012)
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Journal Article
Cardiomyopathy With Restrictive Physiology in Sickle Cell Disease
Niss, Omar, MD, Quinn, Charles T., MD, MS, Lane, Adam, PhD, Daily, Joshua, MD, Khoury, Philip R., MS, Bakeer, Nihal, MD, Kimball, Thomas R., MD, Towbin, Jeffrey A., MD, Malik, Punam, MD, Taylor, Michael D., MD, PhD
Published in JACC. Cardiovascular imaging (01.03.2016)
Published in JACC. Cardiovascular imaging (01.03.2016)
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Journal Article
p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation
Hinge, Ashwini, Xu, Juying, Javier, Jose, Mose, Eucabeth, Kumar, Sachin, Kapur, Reuben, Srour, Edward F., Malik, Punam, Aronow, Bruce J., Filippi, Marie-Dominique
Published in Nature communications (08.02.2017)
Published in Nature communications (08.02.2017)
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Journal Article
Left atrial dysfunction in sickle cell anemia is associated with diffuse myocardial fibrosis, increased right ventricular pressure and reduced exercise capacity
Alsaied, Tarek, Niss, Omar, Tretter, Justin T., Powell, Adam W., Chin, Clifford, Fleck, Robert J., Cnota, James F., Malik, Punam, Quinn, Charles T., Nagueh, Sherif F., Taylor, Michael D., Mazur, Wojciech M.
Published in Scientific reports (04.02.2020)
Published in Scientific reports (04.02.2020)
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Journal Article
Use of induced pluripotent stem cells to recapitulate pulmonary alveolar proteinosis pathogenesis
Suzuki, Takuji, Mayhew, Christopher, Sallese, Anthony, Chalk, Claudia, Carey, Brenna C, Malik, Punam, Wood, Robert E, Trapnell, Bruce C
Published in American journal of respiratory and critical care medicine (15.01.2014)
Published in American journal of respiratory and critical care medicine (15.01.2014)
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Journal Article
A novel human gamma-globin gene vector for genetic correction of sickle cell anemia in a humanized sickle mouse model: critical determinants for successful correction
Perumbeti, Ajay, Higashimoto, Tomoyasu, Urbinati, Fabrizia, Franco, Robert, Meiselman, Herbert J., Witte, David, Malik, Punam
Published in Blood (06.08.2009)
Published in Blood (06.08.2009)
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Journal Article
Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium
Salomonis, Nathan, Dexheimer, Phillip J., Omberg, Larsson, Schroll, Robin, Bush, Stacy, Huo, Jeffrey, Schriml, Lynn, Ho Sui, Shannan, Keddache, Mehdi, Mayhew, Christopher, Shanmukhappa, Shiva Kumar, Wells, James, Daily, Kenneth, Hubler, Shane, Wang, Yuliang, Zambidis, Elias, Margolin, Adam, Hide, Winston, Hatzopoulos, Antonis K., Malik, Punam, Cancelas, Jose A., Aronow, Bruce J., Lutzko, Carolyn
Published in Stem cell reports (12.07.2016)
Published in Stem cell reports (12.07.2016)
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Journal Article
Patient Perspectives on Gene Transfer Therapy for Sickle Cell Disease
Strong, Heather, Mitchell, Monica J., Goldstein-Leever, Alana, Shook, Lisa, Malik, Punam, Crosby, Lori E.
Published in Advances in therapy (01.08.2017)
Published in Advances in therapy (01.08.2017)
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Journal Article
Foamy Virus Vector Carries a Strong Insulator in Its Long Terminal Repeat Which Reduces Its Genotoxic Potential
Goodman, Michael Aaron, Arumugam, Paritha, Pillis, Devin Marie, Loberg, Anastacia, Nasimuzzaman, Mohammed, Lynn, Danielle, van der Loo, Johannes Christiaan Maria, Dexheimer, Phillip Joseph, Keddache, Mehdi, Bauer, Jr, Thomas Roy, Hickstein, Dennis Durand, Russell, David William, Malik, Punam
Published in Journal of virology (01.01.2018)
Published in Journal of virology (01.01.2018)
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Journal Article
Effective hematopoietic stem cell-based gene therapy in a murine model of hereditary pulmonary alveolar proteinosis
Hetzel, Miriam, Lopez-Rodriguez, Elena, Mucci, Adele, Nguyen, Ariane Hai Ha, Suzuki, Takuji, Shima, Kenjiro, Buchegger, Theresa, Dettmer, Sabine, Rodt, Thomas, Bankstahl, Jens P, Malik, Punam, Knudsen, Lars, Schambach, Axel, Hansen, Gesine, Trapnell, Bruce C, Lachmann, Nico, Moritz, Thomas
Published in Haematologica (Roma) (01.04.2020)
Published in Haematologica (Roma) (01.04.2020)
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Journal Article
Beyond the Definitions of the Phenotypic Complications of Sickle Cell Disease : An Update on Management
Kesen, Muge R., Ballas, Samir K., Goldberg, Morton F., Lutty, Gerard A., Dampier, Carlton, Osunkwo, Ifeyinwa, Wang, Winfred C., Hoppe, Carolyn, Hagar, Ward, Darbari, Deepika S., Malik, Punam
Published in TheScientificWorld (01.01.2012)
Published in TheScientificWorld (01.01.2012)
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