Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)
Penning, Thomas D, Talley, John J, Bertenshaw, Stephen R, Carter, Jeffery S, Collins, Paul W, Docter, Stephen, Graneto, Matthew J, Lee, Len F, Malecha, James W, Miyashiro, Julie M, Rogers, Roland S, Rogier, D. J, Yu, Stella S, Anderson, Gary D, Burton, Earl G, Cogburn, J. Nita, Gregory, Susan A, Koboldt, Carol M, Perkins, William E, Seibert, Karen, Veenhuizen, Amy W, Zhang, Yan Y, Isakson, Peter C
Published in Journal of medicinal chemistry (25.04.1997)
Published in Journal of medicinal chemistry (25.04.1997)
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Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib)
Penning, T D, Talley, J J, Bertenshaw, S R, Carter, J S, Collins, P W, Docter, S, Graneto, M J, Lee, L F, Malecha, J W, Miyashiro, J M, Rogers, R S, Rogier, D J, Yu, S S, AndersonGD, Burton, E G, Cogburn, J N, Gregory, S A, Koboldt, C M, Perkins, W E, Seibert, K, Veenhuizen, A W, Zhang, Y Y, Isakson, P C
Published in Journal of medicinal chemistry (25.04.1997)
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Published in Journal of medicinal chemistry (25.04.1997)
Journal Article
Synthesis of potent leukotriene A(4) hydrolase inhibitors. identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid
Penning, TD, Russell, MA, Chen, BB, Chen, HY, Liang, CD, Mahoney, MW, Malecha, JW, Miyashiro, JM, Yu, SS, Askonas, LJ, Gierse, JK, Harding, EI, Highkin, MK, Kachur, JF, Kim, SH, Villani-Price, D, Pyla, EY, Ghoreishi-Haack, NS, Smith, WG
Published in Journal of medicinal chemistry (01.08.2002)
Published in Journal of medicinal chemistry (01.08.2002)
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Applications of crotyldiisopinocampheylboranes in synthesis: a formal total synthesis of (+)-calyculin A
Anderson, OP, Barrett, AGM, Edmunds, JJ, Hachiya, SI, Hendrix, JA, Horita, K, Malecha, JW, Parkinson, CJ, VanSickle, A
Published in Canadian journal of chemistry (01.11.2001)
Published in Canadian journal of chemistry (01.11.2001)
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Synthesis of cinnamic acids and related isosteres as potent and selective alpha v beta 3 receptor antagonists
Penning, Thomas D, Russell, Mark A, Chen, Barbara B, Chen, Helen Y, Desai, Bipin N, Docter, Stephen H, Edwards, David J, Gesicki, Glen J, Liang, Chi-Dean, Malecha, James W, Yu, Stella S, Engleman, V Wayne, Freeman, Sandra K, Hanneke, Melanie L, Shannon, Kristen E, Westlin, Marisa M, Nickols, G Allen
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
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Applications of crotyldiisopinocampheylboranes in synthesis: a formal total synthesis of (+)-calyculin A
Anderson, Oren P, Barrett, Anthony GM, Edmunds, Jeremy J, Hachiya, Shun-Ichiro, Hendrix, James A, Horita, Kiyoshi, Malecha, James W, Parkinson, Christopher J, VanSickle, Andrew
Published in Canadian journal of chemistry (01.11.2001)
Published in Canadian journal of chemistry (01.11.2001)
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Substituted pyrazolyl benzenesulfonamides for the treatment of inflamation
TALLEY JOHN J.,PENNING THOMAS D.,COLLINS PAUL W.,ROGIER DONALD J. JR.,MALECHA JAMES W.,MIYASHIRO JULIE M.,BERTENSHAW STEPHEN R.,KHANNA ISH K.,GRANETOMATTHEW J.,ROGERS ROLAND S.,CARTER JEFFERY S.,DOCT
Year of Publication 23.11.2005
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Year of Publication 23.11.2005
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