Epigenetic upregulation of Schlafen11 renders WNT- and SHH-activated medulloblastomas sensitive to cisplatin
Nakata, Satoshi, Murai, Junko, Okada, Masayasu, Takahashi, Haruhiko, Findlay, Tyler H, Malebranche, Kristen, Parthasarathy, Akhila, Miyashita, Satoshi, Gabdulkhaev, Ramil, Benkimoun, Ilan, Druillennec, Sabine, Chabi, Sara, Hawkins, Eleanor, Miyahara, Hiroaki, Tateishi, Kensuke, Yamashita, Shinji, Yamada, Shiori, Saito, Taiki, On, Jotaro, Watanabe, Jun, Tsukamoto, Yoshihiro, Yoshimura, Junichi, Oishi, Makoto, Nakano, Toshimichi, Imamura, Masaru, Imai, Chihaya, Yamamoto, Tetsuya, Takeshima, Hideo, Sasaki, Atsuo T, Rodriguez, Fausto J, Nobusawa, Sumihito, Varlet, Pascale, Pouponnot, Celio, Osuka, Satoru, Pommier, Yves, Kakita, Akiyoshi, Fujii, Yukihiko, Raabe, Eric H, Eberhart, Charles G, Natsumeda, Manabu
Published in Neuro-oncology (Charlottesville, Va.) (04.05.2023)
Published in Neuro-oncology (Charlottesville, Va.) (04.05.2023)
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Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors
Parkhurst, Ashlyn, Wang, Sabrina Z., Findlay, Tyler R., Malebranche, Kristen J., Odabas, Arman, Alt, Jesse, Maxwell, Micah J., Kaur, Harpreet, Peer, Cody J., Figg, William D., Warren, Katherine E., Slusher, Barbara S., Eberhart, Charles G., Raabe, Eric H., Rubens, Jeffrey A.
Published in Cell death & disease (28.04.2022)
Published in Cell death & disease (28.04.2022)
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ATRT-26. The PI3k inhibitor Paxalisib combines with the novel HDAC1/3 inhibitor RG2833 to improve survival in mice bearing orthotopic xenografts of atypical teratoid/rhabdoid tumors
Findlay, Tyler, Malebranche, Kristen, Raabe, Eric, Eberhart, Charles, Rubens, Jeffrey
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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ATRT-15. COMBINING THE PI3K INHIBITOR PAXALISIB WITH NUCLEOSIDE ANALOG GEMCITABINE TO IMPROVE SURVIVAL OF ATYPICAL TERATOID/RHABDOID TUMORS
Findlay, Tyler, Malebranche, Kristen, Geethadevi, Anupa, Eberhart, Charles, Rubens, Jeffrey, Raabe, Eric
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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ATRT-17. INHIBITING THE MAP KINASE PATHWAY WITH MEK INHIBITOR MIRDAMETINIB SUPPRESSES CANCER GROWTH IN ATYPICAL TERATOID/RHABDOID TUMORS
Deng, Yiming, Malebranche, Kristen, Findlay, Tyler, Geethadevi, Anupa, Eberhart, Charles, Rubens, Jeffrey, Raabe, Eric
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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ATRT-16. THE PI3K INHIBITOR PAXALISIB COMBINES SYNERGISTICALLY WITH THE MEK INHIBITOR MIRDAMETINIB TO TARGET ATYPICAL TERATOID/RHABDOID TUMORS
Malebranche, Kristen, Findlay, Tyler, Geethadevi, Anupa, Eberhart, Charles, Raabe, Eric, Rubens, Jeffrey
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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ATRT-09. COMBINATION OF THE PI3K INHIBITOR PAXALISIB WITH THE NUCLEOSIDE ANALOG GEMCITABINE ACTIVATES THE INTEGRATED STRESS RESPONSE AND EXTENDS SURVIVAL IN ORTHOTOPIC MODELS OF ATYPICAL TERATOID/RHABDOID TUMORS
Findlay, Tyler, Malebranche, Kristen, Geethadevi, Anupa, Eberhart, Charles, Raabe, Eric, Rubens, Jeffrey
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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ATRT-04. TARGETING THE COREST COMPLEX HELPS REPROGRAM AT/RT’S ABNORMAL EPIGENETIC LANDSCAPE TOWARD A DIFFERENTIATION PHENOTYPE
Geethadevi, Anupa, Collard, Marianne, Vaidya, Nikhil, Findlay, Tyler, Malebranche, Kristen, Eberhart, Charles, Raabe, Eric, Cole, Philip, Alani, Rhoda, Rubens, Jeffrey
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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Abstract 5226: The PI3K inhibitor Paxalisib combines synergistically with the pan-Raf inhibitor TAK580 (DAY 101) to extend survival in orthotopic xenograft models of atypical teratoid/rhabdoid tumors
Malebranche, Kristen, Findlay, Tyler, Eberhart, Charles, Raabe, Eric, Rubens, Jeffrey
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 5225: The PI3K inhibitor Paxalisib combines with the novel HDAC1/3 inhibitor RG2833 to improve survival in mice bearing orthotopic xenografts of atypical teratoid/rhabdoid tumors
Findlay, Tyler, Malebranche, Kristen, Eberhart, Charles, Raabe, Eric, Rubens, Jeffrey
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 6565: Improving survival of atypical teratoid/rhabdoid tumor orthotopic xenografts through the combination of PI3K inhibitor paxalisib and nucleoside analog gemcitabine
Findlay, Tyler, Malebranche, Kristen, Geethadevi, Anupa, Eberhart, Charles, Rubens, Jeffrey, Raabe, Eric
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 6498: MEK inhibitor mirdametinib suppresses MAP kinase pathway activity and inhibits tumor growth in atypical teratoid/rhabdoid tumors
Deng, Yiming, Malebranche, Kristen, Findlay, Tyler, Geethadevi, Anupa, Eberhart, Charles, Rubens, Jeffrey, Raabe, Eric
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 5490: Combination of the PI3k inhibitor Paxalisib with the nucleoside analog Gemcitabine over-activates the integrated stress response and induces atypical teratoid/rhabdoid tumor cell death
Findlay, Tyler, Malebranche, Kristen, Geethadevi, Anupa, Raabe, Eric, Eberhart, Charles, Rubens, Jeffrey
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 5509: The PI3K inhibitor Paxalisib combines synergistically with the MEK inhibitor Mirdametinib to target atypical teratoid/rhabdoid tumors
Malebranche, Kristen J., Findlay, Tyler, Geethadevi, Anupa, Eberhart, Charles, Raabe, Eric, Rubens, Jeffrey
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 1141: The CoREST complex as a novel target to disrupt AT/RT’s abnormal epigenetic landscape
Geethadevi, Anupa, Collard, Marianne, Vaidya, Nikhil, Findlay, Tyler, Malebranche, Kristen, Eberhart, Charles, Raabe, Eric, Cole, Philip, Alani, Rhoda, Rubens, Jeffrey
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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